Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

Biochemical Society Transactions

Volumn 32, Issue 1, 2004, Pages 28-32

  Morikis, D ^a   Soulika, A M ^b   Mallik, B ^a   Klepeis, J L ^c   Floudas, C A ^c   Lambris, J D ^b  

^a University of California Riverside   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Princeton University   (United States)

Author keywords

Complement system; Compstatin; Drug design; Molecular dynamics; NMR; Peptide

Indexed keywords

COMPLEMENT COMPONENT C3 RECEPTOR; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3B; COMPSTATIN; PEPTIDE; STATIN; UNCLASSIFIED DRUG;

CALCULATION; COMBINATORIAL CHEMISTRY; CONFERENCE PAPER; GENE LIBRARY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; PROTEIN TARGETING; SIMULATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPLEMENT C3; DRUG DESIGN; HUMANS; PEPTIDES, CYCLIC;

TRIXIS;

EID: 1442309694     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0320028     Document Type: Conference Paper

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