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Volumn 93, Issue 5, 1999, Pages 1658-1667

Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; DOXORUBICIN; INTEGRIN; MELPHALAN; RECEPTOR; VERY LATE ACTIVATION ANTIGEN 5;

EID: 0033105537     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.5.1658.405a19_1658_1667     Document Type: Article
Times cited : (788)

References (67)
  • 1
    • 0028918796 scopus 로고
    • P-glycoprotein-mediated multidrug resistance in tumor cells: Biochemistry, clinical relevance and modulation
    • London, UK, Elsevier Science
    • Schustik C, Dalton WS, Gros P: P-glycoprotein-mediated multidrug resistance in tumor cells: Biochemistry, clinical relevance and modulation, in: Molecular Aspects of Medicine, vol 16. London, UK, Elsevier Science, 1995, p 1
    • (1995) Molecular Aspects of Medicine , vol.16 , pp. 1
    • Schustik, C.1    Dalton, W.S.2    Gros, P.3
  • 2
    • 0024511372 scopus 로고
    • Immunohistochemical detection and quantification of P-glycoprotein in multiple drug-resistant human myeloma cells: Association with level of drug resistance and drug accumulation
    • Dalton WS, Grogan TM, Rybski JA, Scheper RJ, Richter L, Kailey J, Broxterman HJ, Pinedo HM, Salmon SE: Immunohistochemical detection and quantification of P-glycoprotein in multiple drug-resistant human myeloma cells: Association with level of drug resistance and drug accumulation. Blood 73:747, 1989
    • (1989) Blood , vol.73 , pp. 747
    • Dalton, W.S.1    Grogan, T.M.2    Rybski, J.A.3    Scheper, R.J.4    Richter, L.5    Kailey, J.6    Broxterman, H.J.7    Pinedo, H.M.8    Salmon, S.E.9
  • 3
    • 0015312069 scopus 로고
    • Effects of intercellular contact on repair of radiation damage
    • Durand RE, Sutherland RM: Effects of intercellular contact on repair of radiation damage. Exp Cell Res 71:75, 1972
    • (1972) Exp Cell Res , vol.71 , pp. 75
    • Durand, R.E.1    Sutherland, R.M.2
  • 7
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Hunter F: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124:619, 1994
    • (1994) J Cell Biol , vol.124 , pp. 619
    • Frisch, S.M.1    Hunter, F.2
  • 9
    • 0027306831 scopus 로고
    • Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes
    • Schuetz JD, Schuetz EG: Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes. Cell Growth Diff 4:31, 1993
    • (1993) Cell Growth Diff , vol.4 , pp. 31
    • Schuetz, J.D.1    Schuetz, E.G.2
  • 10
    • 0028846140 scopus 로고    scopus 로고
    • Integrin mediated signal transduction in oncogenesis: An overview
    • Dedhar S: Integrin mediated signal transduction in oncogenesis: An overview. Cancer Metas Rev 14:55, 1996
    • (1996) Cancer Metas Rev , vol.14 , pp. 55
    • Dedhar, S.1
  • 11
    • 0028044834 scopus 로고
    • Signal transduction by integrins and its role in the regulation of tumor growth
    • Juliano R: Signal transduction by integrins and its role in the regulation of tumor growth: Cancer Metas Rev 13:25, 1994
    • (1994) Cancer Metas Rev , vol.13 , pp. 25
    • Juliano, R.1
  • 12
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA, Brugge JS: Integrins and signal transduction pathways: The road taken. Science 268:233, 1995
    • (1995) Science , vol.268 , pp. 233
    • Clark, E.A.1    Brugge, J.S.2
  • 14
    • 0028983407 scopus 로고
    • The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression
    • Zhang Z, Vuori K, Reed JC, Rouslahti E: The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc Natl Acad Sci USA 92(13):6161, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.13 , pp. 6161
    • Zhang, Z.1    Vuori, K.2    Reed, J.C.3    Rouslahti, E.4
  • 15
    • 0031021158 scopus 로고    scopus 로고
    • Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanism
    • Scott G, Cassidy L, Busacco A: Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanism. J Invest Dermatol 108:147, 1997
    • (1997) J Invest Dermatol , vol.108 , pp. 147
    • Scott, G.1    Cassidy, L.2    Busacco, A.3
  • 16
    • 0030990594 scopus 로고    scopus 로고
    • Induction of apoptosis in human neuroblastoma cells by abrogation of integrin-mediated cell adhesion
    • Rozzo C, Chiesa C, Caridi G, Pagnan G, Ponzoni M: Induction of apoptosis in human neuroblastoma cells by abrogation of integrin-mediated cell adhesion. Int J Cancer 70:688, 1997
    • (1997) Int J Cancer , vol.70 , pp. 688
    • Rozzo, C.1    Chiesa, C.2    Caridi, G.3    Pagnan, G.4    Ponzoni, M.5
  • 17
    • 0029830927 scopus 로고    scopus 로고
    • Integrin activation suppresses etoposide-induced DNA strand breakage in cultured murine tumor-derived endothelial cells
    • Hoyt DG, Rusnak JM, Mannix RJ, Modzelewski RA, Johnson CS, Lazo JS: Integrin activation suppresses etoposide-induced DNA strand breakage in cultured murine tumor-derived endothelial cells. Cancer Res 56:2146, 1996
    • (1996) Cancer Res , vol.56 , pp. 2146
    • Hoyt, D.G.1    Rusnak, J.M.2    Mannix, R.J.3    Modzelewski, R.A.4    Johnson, C.S.5    Lazo, J.S.6
  • 19
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO: Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 69:11, 1992
    • (1992) Cell , vol.69 , pp. 11
    • Hynes, R.O.1
  • 20
    • 0027154853 scopus 로고
    • Expression of multiple β1 integrins on circulating monoclonal B cells in patients with multiple myeloma
    • Jensen GS, Belch AR, Mant MJ, Ruether BA, Tacyshyn BR, Pilarsky LM: Expression of multiple β1 integrins on circulating monoclonal B cells in patients with multiple myeloma. Am J Hematol 43:29, 1993
    • (1993) Am J Hematol , vol.43 , pp. 29
    • Jensen, G.S.1    Belch, A.R.2    Mant, M.J.3    Ruether, B.A.4    Tacyshyn, B.R.5    Pilarsky, L.M.6
  • 23
    • 0025161990 scopus 로고
    • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
    • Elices MJ, Osbom L, Takada Y, Crouse C, Lujowskyj S, Hemler ME, Lobb RR: VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60:577, 1990
    • (1990) Cell , vol.60 , pp. 577
    • Elices, M.J.1    Osbom, L.2    Takada, Y.3    Crouse, C.4    Lujowskyj, S.5    Hemler, M.E.6    Lobb, R.R.7
  • 25
    • 0031990830 scopus 로고    scopus 로고
    • Rescue from apoptosis in early (CD34-selected) versus late (non-CD-34-selected) human hematopoietic cells by very later antigen 4- and vascular cell adhesion molecule (VCAM) 1-dependent adhesion to bone marrow stromal cells
    • Wang MW-J, Consoli U, Lane CM, Durett A, Lauppe MJ, Champlin R, Andreeff M, Deisseroth AB: Rescue from apoptosis in early (CD34-selected) versus late (non-CD-34-selected) human hematopoietic cells by very later antigen 4- and vascular cell adhesion molecule (VCAM) 1-dependent adhesion to bone marrow stromal cells. Cell Growth Diff 9:105, 1998
    • (1998) Cell Growth Diff , vol.9 , pp. 105
    • Wang, M.W.-J.1    Consoli, U.2    Lane, C.M.3    Durett, A.4    Lauppe, M.J.5    Champlin, R.6    Andreeff, M.7    Deisseroth, A.B.8
  • 26
    • 0028195006 scopus 로고
    • Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells
    • Koopman G, Keehen RMJ, Lindhout E, Newman W, Shimizu Y, van Seventer GA, de Groot C, Pals ST: Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. J Immunol 152:3760, 1994
    • (1994) J Immunol , vol.152 , pp. 3760
    • Koopman, G.1    Keehen, R.M.J.2    Lindhout, E.3    Newman, W.4    Shimizu, Y.5    Van Seventer, G.A.6    De Groot, C.7    Pals, S.T.8
  • 27
    • 0027461164 scopus 로고
    • Antimetastatic effect by anti-adhesion therapy with cell-adhesive peptide of fibronectin in combination with anticancer drugs
    • Saiki I, Yoneda J, Kobayashi H, Igarashi Y, Komazawa H, Ishizaki Y, Kato I, Azuma I: Antimetastatic effect by anti-adhesion therapy with cell-adhesive peptide of fibronectin in combination with anticancer drugs. Jpn J Cancer Res 84:326, 1993
    • (1993) Jpn J Cancer Res , vol.84 , pp. 326
    • Saiki, I.1    Yoneda, J.2    Kobayashi, H.3    Igarashi, Y.4    Komazawa, H.5    Ishizaki, Y.6    Kato, I.7    Azuma, I.8
  • 29
    • 0026443460 scopus 로고
    • The critical role of IL-6 and macrophage colony stimulating factor in the pathogenesis of bone lesions in multiple myeloma
    • Bataille R, Chappard D, Klein B: The critical role of IL-6 and macrophage colony stimulating factor in the pathogenesis of bone lesions in multiple myeloma. Int J Clin Lab Res 21:283, 1992
    • (1992) Int J Clin Lab Res , vol.21 , pp. 283
    • Bataille, R.1    Chappard, D.2    Klein, B.3
  • 30
    • 0027133422 scopus 로고
    • Adhesion of human myeloma cell lines to bone marrow stromal cells stimulates IL-6 secretion
    • Uchiyama H, Barut BA, Mohrbacher AF, Chauhan D, Anderson KC: Adhesion of human myeloma cell lines to bone marrow stromal cells stimulates IL-6 secretion. Blood 82:3712, 1993
    • (1993) Blood , vol.82 , pp. 3712
    • Uchiyama, H.1    Barut, B.A.2    Mohrbacher, A.F.3    Chauhan, D.4    Anderson, K.C.5
  • 31
    • 0029665081 scopus 로고    scopus 로고
    • Signal transduction through the beta 1 integrin family surface adhesion molecules VLA-4 and VLA-5 of human B-cell precursors activates CD19 receptor-associated protein-tyrosine kinases
    • Xiao J, Messinger Y, Jin J, Myers DE, Bolen JB, Uckun FM: Signal transduction through the beta 1 integrin family surface adhesion molecules VLA-4 and VLA-5 of human B-cell precursors activates CD19 receptor-associated protein-tyrosine kinases. J Biol Chem 271(13): 7659, 1996
    • (1996) J Biol Chem , vol.271 , Issue.13 , pp. 7659
    • Xiao, J.1    Messinger, Y.2    Jin, J.3    Myers, D.E.4    Bolen, J.B.5    Uckun, F.M.6
  • 32
    • 0028925477 scopus 로고
    • FAK) is tyrosine phosphorylated after engagement of α4β1 and α5β1 integrins on human t-lymphoblastic cells
    • FAK) is tyrosine phosphorylated after engagement of α4β1 and α5β1 integrins on human t-lymphoblastic cells. Cell Immunol 161:8, 1995
    • (1995) Cell Immunol , vol.161 , pp. 8
    • Nojima, Y.1    Tachibana, K.2    Sato, T.3    Sclossman, S.F.4    Morimoto, C.5
  • 33
    • 0026476697 scopus 로고
    • FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes
    • FAK): A point of convergence in the action of neuropeptides, integrins, and oncogenes. Cell 71:891, 1992
    • (1992) Cell , vol.71 , pp. 891
    • Zachary, I.1    Rozengurt, E.2
  • 34
    • 0027938974 scopus 로고
    • Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
    • Chen H-C, Guan J-L: Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 91:10148, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10148
    • Chen, H.-C.1    Guan, J.-L.2
  • 35
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124:619, 1994
    • (1994) J Cell Biol , vol.124 , pp. 619
    • Frisch, S.M.1    Francis, H.2
  • 38
    • 0022485356 scopus 로고
    • Characterization of a new drug-resistant human myeloma cell line that expresses P-glycoprotein
    • Dalton WS, Durie BGM, Alberts DS, Gerlach JH, Cress AE: Characterization of a new drug-resistant human myeloma cell line that expresses P-glycoprotein. Cancer Res 46:2125, 1986
    • (1986) Cancer Res , vol.46 , pp. 2125
    • Dalton, W.S.1    Durie, B.G.M.2    Alberts, D.S.3    Gerlach, J.H.4    Cress, A.E.5
  • 39
    • 0026035533 scopus 로고
    • Development and characterization of a melphalan resistant human multiple myeloma cell line
    • Bellamy WT, Dalton WS, Gleason MC, Grogan TM, Trent JM: Development and characterization of a melphalan resistant human multiple myeloma cell line. Cancer Res 51:995, 1991
    • (1991) Cancer Res , vol.51 , pp. 995
    • Bellamy, W.T.1    Dalton, W.S.2    Gleason, M.C.3    Grogan, T.M.4    Trent, J.M.5
  • 40
    • 0029794419 scopus 로고    scopus 로고
    • Upregulated expression of Bcl-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide
    • Tu Y, Xu F, Liu J, Vescio R, Berenson J, Fady C, Lichtenstein A: Upregulated expression of Bcl-2 in multiple myeloma cells induced by exposure to doxorubicin, etoposide, and hydrogen peroxide. Blood 88:1805, 1996
    • (1996) Blood , vol.88 , pp. 1805
    • Tu, Y.1    Xu, F.2    Liu, J.3    Vescio, R.4    Berenson, J.5    Fady, C.6    Lichtenstein, A.7
  • 41
    • 0027240368 scopus 로고
    • Quantitative polymerase chain reaction analysis of MDR1 mRNA in multiple myeloma cell lines and clinical specimens
    • Futscher BW, Blake LL, Gerlach JH, Grogan TM, Dalton WS: Quantitative polymerase chain reaction analysis of MDR1 mRNA in multiple myeloma cell lines and clinical specimens. Anal Biochem 213:414, 1993
    • (1993) Anal Biochem , vol.213 , pp. 414
    • Futscher, B.W.1    Blake, L.L.2    Gerlach, J.H.3    Grogan, T.M.4    Dalton, W.S.5
  • 42
    • 0029888018 scopus 로고    scopus 로고
    • Apoptosis induced by erytheroid differentiation of human leukemia cell lines is inhibited by Bcl-XL
    • Benito A, Silver M, Grillot D, Nunez G, Fernandez-Luna JL: Apoptosis induced by erytheroid differentiation of human leukemia cell lines is inhibited by Bcl-XL. Blood 87:3837, 1996
    • (1996) Blood , vol.87 , pp. 3837
    • Benito, A.1    Silver, M.2    Grillot, D.3    Nunez, G.4    Fernandez-Luna, J.L.5
  • 43
    • 0028025021 scopus 로고
    • Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematapoietic cells
    • Abbaszadegan MR, Futscher BW, Klimecki WT, List A, Dalton WS: Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematapoietic cells. Cancer Res 54:4676, 1994
    • (1994) Cancer Res , vol.54 , pp. 4676
    • Abbaszadegan, M.R.1    Futscher, B.W.2    Klimecki, W.T.3    List, A.4    Dalton, W.S.5
  • 44
    • 0031609164 scopus 로고    scopus 로고
    • Activation of the LRP (lung resistance-associated protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine
    • Komarov P, Shtil A, Holian O, Tee L, Buckingham L, Mechetner E, Roninson I, Coon J: Activation of the LRP (lung resistance-associated protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine. Oncology Res 10:185, 1998
    • (1998) Oncology Res , vol.10 , pp. 185
    • Komarov, P.1    Shtil, A.2    Holian, O.3    Tee, L.4    Buckingham, L.5    Mechetner, E.6    Roninson, I.7    Coon, J.8
  • 45
    • 0024329916 scopus 로고
    • Stimulation of growth in human and murine cells by adriamycin
    • Vichi P, Tritton TR: Stimulation of growth in human and murine cells by adriamycin. Cancer Res 49:2679, 1989
    • (1989) Cancer Res , vol.49 , pp. 2679
    • Vichi, P.1    Tritton, T.R.2
  • 46
    • 0031574304 scopus 로고    scopus 로고
    • Soluble integrin ligands and growth factors independently rescue neuroblastoma cells from apoptosis under nonadherent conditions
    • Bozzo C, Bellomo G, Silengo L, Tarone G, Altruda F: Soluble integrin ligands and growth factors independently rescue neuroblastoma cells from apoptosis under nonadherent conditions. Exp Cell Res 237:326, 1997
    • (1997) Exp Cell Res , vol.237 , pp. 326
    • Bozzo, C.1    Bellomo, G.2    Silengo, L.3    Tarone, G.4    Altruda, F.5
  • 47
    • 0030476060 scopus 로고    scopus 로고
    • Evidence for cytoplasmic P-glycoprotein location associated with increased multidrug resistance and resistance to chemosensisitzers
    • Abbaszadegan MR, Cress AE, Futscher BW, Bellamy WT, Dalton WS: Evidence for cytoplasmic P-glycoprotein location associated with increased multidrug resistance and resistance to chemosensisitzers. Cancer Res 56(23):5435, 1996
    • (1996) Cancer Res , vol.56 , Issue.23 , pp. 5435
    • Abbaszadegan, M.R.1    Cress, A.E.2    Futscher, B.W.3    Bellamy, W.T.4    Dalton, W.S.5
  • 49
    • 0029905923 scopus 로고    scopus 로고
    • Cell surface phenotype and increased penetration of human multidrug-resistant ovarian carcinoma cells into in vitro collagen-fibroblasts matrix
    • Sedlak J, Sedlakova O, Hlavcak P, Hunakova L, Bizik J, Grofova M, Chorvath B: Cell surface phenotype and increased penetration of human multidrug-resistant ovarian carcinoma cells into in vitro collagen-fibroblasts matrix. Neoplasma 43:389, 1996
    • (1996) Neoplasma , vol.43 , pp. 389
    • Sedlak, J.1    Sedlakova, O.2    Hlavcak, P.3    Hunakova, L.4    Bizik, J.5    Grofova, M.6    Chorvath, B.7
  • 51
    • 0030612249 scopus 로고    scopus 로고
    • Functional role of a4b1 and a5b1 integrin fibronectin receptors expressed on adriamycin-resistant MCF-7 human mammary carcinoma cells
    • Nista A, Leonetti C, Bernardini G, Mattoni M, Santoni A: Functional role of a4b1 and a5b1 integrin fibronectin receptors expressed on adriamycin-resistant MCF-7 human mammary carcinoma cells. Int J Cancer 72:133, 1997
    • (1997) Int J Cancer , vol.72 , pp. 133
    • Nista, A.1    Leonetti, C.2    Bernardini, G.3    Mattoni, M.4    Santoni, A.5
  • 53
    • 0028241065 scopus 로고
    • Production of fibronectin and adherence to fibronectin by human myeloma cell lines
    • Van Riet I, De Greef C, Del Favero H, Demanet C, Van Camp B: Production of fibronectin and adherence to fibronectin by human myeloma cell lines. Br J Hematol 87:258, 1994
    • (1994) Br J Hematol , vol.87 , pp. 258
    • Van Riet, I.1    De Greef, C.2    Del Favero, H.3    Demanet, C.4    Van Camp, B.5
  • 54
    • 0025824335 scopus 로고
    • High plasma fibronectin levels in multiple myeloma patients: Possible mechanism and clinical implications
    • Paizi M, Manaster J, Quitt M, Spira G: High plasma fibronectin levels in multiple myeloma patients: Possible mechanism and clinical implications. Scand J Immunol 34:285, 1991
    • (1991) Scand J Immunol , vol.34 , pp. 285
    • Paizi, M.1    Manaster, J.2    Quitt, M.3    Spira, G.4
  • 55
    • 0028968646 scopus 로고
    • Fibronectin expression in human mesangial cell cultures and its alteration by adriamycin
    • Soose M, Wenzel S, Padur A, Oberst D, Stolte H: Fibronectin expression in human mesangial cell cultures and its alteration by adriamycin. Cell Biol Toxicol 11:51, 1995
    • (1995) Cell Biol Toxicol , vol.11 , pp. 51
    • Soose, M.1    Wenzel, S.2    Padur, A.3    Oberst, D.4    Stolte, H.5
  • 56
    • 0030739983 scopus 로고    scopus 로고
    • Detection of multidrug resistance gene expression in multiple myeloma
    • Dalton WS: Detection of multidrug resistance gene expression in multiple myeloma. Leukemia 11(7):1165, 1997
    • (1997) Leukemia , vol.11 , Issue.7 , pp. 1165
    • Dalton, W.S.1
  • 57
    • 0030612602 scopus 로고    scopus 로고
    • Regulation of Bcl-x1 expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor
    • Rodeck U, Jost M, DuHadaway J, Kari C, Jensen PJ, Risse B, Ewert DL: Regulation of Bcl-x1 expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor. Proc Natl Acad Sci USA 94:5067, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5067
    • Rodeck, U.1    Jost, M.2    DuHadaway, J.3    Kari, C.4    Jensen, P.J.5    Risse, B.6    Ewert, D.L.7
  • 58
    • 0029087659 scopus 로고
    • Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation
    • Hurley RW, McCarthy JB, Verfaillie CM: Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest 96:511, 1995
    • (1995) J Clin Invest , vol.96 , pp. 511
    • Hurley, R.W.1    McCarthy, J.B.2    Verfaillie, C.M.3
  • 60
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phophonisositide 3-kinase to cell survival and beyond
    • Marte BM, Downward J: PKB/Akt: Connecting phophonisositide 3-kinase to cell survival and beyond. TIBS 22:355, 1997
    • (1997) TIBS , vol.22 , pp. 355
    • Marte, B.M.1    Downward, J.2
  • 61
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME: Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 92:231, 1997
    • (1997) Cell , vol.92 , pp. 231
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 62
    • 0028834557 scopus 로고
    • Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: Phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating factor
    • Scheid MP, Lauener RW, Duronio V: Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: Phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating factor. Biochem J 312:159, 1995
    • (1995) Biochem J , vol.312 , pp. 159
    • Scheid, M.P.1    Lauener, R.W.2    Duronio, V.3
  • 64
    • 0030839766 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for integrin stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
    • King WG, Mattaliano MD, Chan TO, Tsichlis RN, Brugge JS: Phosphatidylinositol 3-kinase is required for integrin stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol Cell Biol 17(8):4406, 1997
    • (1997) Mol Cell Biol , vol.17 , Issue.8 , pp. 4406
    • King, W.G.1    Mattaliano, M.D.2    Chan, T.O.3    Tsichlis, R.N.4    Brugge, J.S.5
  • 66
    • 0027939187 scopus 로고
    • Integrin-mediated cell adhesion activates mitogen-activated protein kinases
    • Chen Q, Kinch MS, Lin TH, Burridge K, Juliano RL: Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J Biol Chem 269:26602, 1994
    • (1994) J Biol Chem , vol.269 , pp. 26602
    • Chen, Q.1    Kinch, M.S.2    Lin, T.H.3    Burridge, K.4    Juliano, R.L.5
  • 67
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau N, Sympson CJ, Werb Z, Bissell MJ: Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 267(5199): 891, 1995
    • (1995) Science , vol.267 , Issue.5199 , pp. 891
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3    Bissell, M.J.4


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