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Volumn 62, Issue 21, 2002, Pages 6304-6311

Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CHEMOKINE RECEPTOR CXCR4; IMATINIB; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; S6 KINASE; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; STROMAL CELL DERIVED FACTOR 1ALPHA;

EID: 0036830045     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (268)

References (48)
  • 1
    • 0028097472 scopus 로고
    • Pharmaceutical research in molecular oncology
    • Gibbs, J. B., and Oliff, A. Pharmaceutical research in molecular oncology. Cell. 79: 193-198, 1994.
    • (1994) Cell , vol.79 , pp. 193-198
    • Gibbs, J.B.1    Oliff, A.2
  • 2
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Levitzki, A., and Gazit, A. Tyrosine kinase inhibition: An approach to drug development. Science (Wash. DC), 267: 1782-1788, 1995.
    • (1995) Science (Wash. DC) , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 3
    • 0032857449 scopus 로고    scopus 로고
    • The biology of stem cell factor and its receptor C-kit
    • Ashman, L. K. The biology of stem cell factor and its receptor C-kit. Int. J. Biochem. Cell Biol., 31: 1037-1051, 1999.
    • (1999) Int. J. Biochem. Cell Biol. , vol.31 , pp. 1037-1051
    • Ashman, L.K.1
  • 4
    • 0032828882 scopus 로고    scopus 로고
    • Early signaling pathways activated by c-Kit in hematopoietic cells
    • Linnekin, D. Early signaling pathways activated by c-Kit in hematopoietic cells. Int. J. Biochem. Cell Biol., 31: 1053-1074, 1999.
    • (1999) Int. J. Biochem. Cell Biol. , vol.31 , pp. 1053-1074
    • Linnekin, D.1
  • 5
    • 0025770646 scopus 로고
    • A receptor tyrosine kinase specific to hematopoietic stern and progenitor cell-enriched populations
    • Matthews, W., Jordan, C. T., Wiegand, G. W., Pardoll, D., and Lemischka, I. R. A receptor tyrosine kinase specific to hematopoietic stern and progenitor cell-enriched populations. Cell, 65: 1143-1152, 1991.
    • (1991) Cell , vol.65 , pp. 1143-1152
    • Matthews, W.1    Jordan, C.T.2    Wiegand, G.W.3    Pardoll, D.4    Lemischka, I.R.5
  • 6
    • 0026318821 scopus 로고
    • Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer
    • Hibi, K., Takahashi, T., Sekido, Y., Ueda, R., Hida, T., Ariyoshi, Y., and Takagi, H. Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer. Oncogene, 6: 2291-2296, 1991.
    • (1991) Oncogene , vol.6 , pp. 2291-2296
    • Hibi, K.1    Takahashi, T.2    Sekido, Y.3    Ueda, R.4    Hida, T.5    Ariyoshi, Y.6    Takagi, H.7
  • 8
    • 0027390395 scopus 로고
    • Expression of the protooncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts
    • Rygaard, K., Nakamura, T., and Spang-Thomsen, M. Expression of the protooncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts. Br. J. Cancer, 67: 37-46, 1993.
    • (1993) Br. J. Cancer , vol.67 , pp. 37-46
    • Rygaard, K.1    Nakamura, T.2    Spang-Thomsen, M.3
  • 9
    • 0027418615 scopus 로고
    • Recombinant human stem cell factor mediates chemotaxis of small-cell lung cancer cell lines aberrantly expressing the c-kit protooncogene
    • Sekido, Y., Takahashi, T., Ueda, R., Takahashi, M., Suzuki, H., Nishida, K., Tsukamoto, T., Hida, T., Shimokata, K., Zsebo, K. M., et al. Recombinant human stem cell factor mediates chemotaxis of small-cell lung cancer cell lines aberrantly expressing the c-kit protooncogene. Cancer Res., 53: 1709-1714, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1709-1714
    • Sekido, Y.1    Takahashi, T.2    Ueda, R.3    Takahashi, M.4    Suzuki, H.5    Nishida, K.6    Tsukamoto, T.7    Hida, T.8    Shimokata, K.9    Zsebo, K.M.10
  • 10
    • 0027818682 scopus 로고
    • c-myc expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines
    • Plummer, H., 3rd, Catlett, J., Leftwich, J., Armstrong, B., Carlson, P., Huff, T., and Krystal, G. c-myc expression correlates with suppression of c-kit protooncogene expression in small cell lung cancer cell lines. Cancer Res., 53: 4337-4342, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4337-4342
    • Plummer H. III1    Catlett, J.2    Leftwich, J.3    Armstrong, B.4    Carlson, P.5    Huff, T.6    Krystal, G.7
  • 11
    • 0030069519 scopus 로고    scopus 로고
    • Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor
    • Krystal, G. W., Hines, S. J., and Organ, C. P. Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor. Cancer Res., 56: 370-376, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 370-376
    • Krystal, G.W.1    Hines, S.J.2    Organ, C.P.3
  • 12
    • 0029952728 scopus 로고    scopus 로고
    • Specific growth inhibition of small-cell lung cancer cells by adenovirus vector expressing antisense c-kit transcripts
    • Yamanishi, Y., Maeda, H., Hiyama, K., Ishiolka, S., and Yamakido, M. Specific growth inhibition of small-cell lung cancer cells by adenovirus vector expressing antisense c-kit transcripts. Jpn. J. Cancer Res., 87: 534-542, 1996.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 534-542
    • Yamanishi, Y.1    Maeda, H.2    Hiyama, K.3    Ishiolka, S.4    Yamakido, M.5
  • 13
    • 0030980383 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins
    • Krystal, G. W., Carlson, P., and Litz, J. Induction of apoptosis and inhibition of small cell lung cancer growth by the quinoxaline tyrphostins. Cancer Res., 57: 2203-2208, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2203-2208
    • Krystal, G.W.1    Carlson, P.2    Litz, J.3
  • 14
    • 0034691761 scopus 로고    scopus 로고
    • Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571
    • Wang, W. L., Healy, M. E., Sattler, M., Verma, S., Lin, J., Maulik, G., Stiles, C. D., Griffin, J. D., Johnson, B. E., and Salgia, R. Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571. Oncogene, 19: 3521-3528, 2000.
    • (2000) Oncogene , vol.19 , pp. 3521-3528
    • Wang, W.L.1    Healy, M.E.2    Sattler, M.3    Verma, S.4    Lin, J.5    Maulik, G.6    Stiles, C.D.7    Griffin, J.D.8    Johnson, B.E.9    Salgia, R.10
  • 15
    • 0033883653 scopus 로고    scopus 로고
    • The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth
    • Krystal, G. W., Honsawek, S., Litz, J., and Buchdunger, E. The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth. Clin. Cancer Res., 6: 3319-3326, 2000.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3319-3326
    • Krystal, G.W.1    Honsawek, S.2    Litz, J.3    Buchdunger, E.4
  • 16
    • 0035899418 scopus 로고    scopus 로고
    • STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications
    • Tuveson, D. A., Willis, N. A., Jacks, T., Griffin, J. D., Singer, S., Fletcher, C. D., Fletcher, J. A., and Demetri, G. D. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: Biological and clinical implications. Oncogene, 20: 5054-5058, 2001.
    • (2001) Oncogene , vol.20 , pp. 5054-5058
    • Tuveson, D.A.1    Willis, N.A.2    Jacks, T.3    Griffin, J.D.4    Singer, S.5    Fletcher, C.D.6    Fletcher, J.A.7    Demetri, G.D.8
  • 17
    • 0035328851 scopus 로고    scopus 로고
    • Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells
    • Krystal, G. W., Honsawek, S., Kiewlich, D., Liang, C., Vasile, S., Sun, L., McMahon, G., and Lipson, K. E. Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells. Cancer Res., 61: 3660-3668, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3660-3668
    • Krystal, G.W.1    Honsawek, S.2    Kiewlich, D.3    Liang, C.4    Vasile, S.5    Sun, L.6    McMahon, G.7    Lipson, K.E.8
  • 18
    • 0032193739 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 α and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: A potential mechanism for cooperative induction of chemotaxis
    • Dutt, P., Wang, J. F., and Groopman, J. E. Stromal cell-derived factor-1 α and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: A potential mechanism for cooperative induction of chemotaxis. J Immunol., 161: 3652-3658, 1998.
    • (1998) J. Immunol. , vol.161 , pp. 3652-3658
    • Dutt, P.1    Wang, J.F.2    Groopman, J.E.3
  • 19
    • 0031985282 scopus 로고    scopus 로고
    • In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: Stromal cell-derived factor-1, steel factor, and the bone marrow environment
    • Kim, C. H., and Broxmeyer, H. E. In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood, 91: 100-110, 1998.
    • (1998) Blood , vol.91 , pp. 100-110
    • Kim, C.H.1    Broxmeyer, H.E.2
  • 21
    • 0034141444 scopus 로고    scopus 로고
    • Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: Possible role in progenitor survival
    • Lataillade, J. J., Clay, D., Dupuy, C., Rigal, S., Jasmin, C., Bourin, P., and Le Bousse-Kerdiles, M. C. Chemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood, 95: 756-768, 2000.
    • (2000) Blood , vol.95 , pp. 756-768
    • Lataillade, J.J.1    Clay, D.2    Dupuy, C.3    Rigal, S.4    Jasmin, C.5    Bourin, P.6    Le Bousse-Kerdiles, M.C.7
  • 22
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi, D., and Zlomik, A. The biology of chemokines and their receptors. Annu. Rev. Immunol., 18: 217-242, 2000.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 217-242
    • Rossi, D.1    Zlomik, A.2
  • 23
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik, A., and Yoshie, O. Chemokines: A new classification system and their role in immunity. Immunity, 12: 121-127, 2000.
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 24
    • 0029906582 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin
    • Nagasawa, T., Nakajima, T., Tachibana, K., Iizasa, H., Bleul, C. C., Yoshie, O., Matsushima, K., Yoshida, N., Springer, T. A., and Kishimoto, T. Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc. Natl. Acad. Sci. USA, 93: 14726-14729, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14726-14729
    • Nagasawa, T.1    Nakajima, T.2    Tachibana, K.3    Iizasa, H.4    Bleul, C.C.5    Yoshie, O.6    Matsushima, K.7    Yoshida, N.8    Springer, T.A.9    Kishimoto, T.10
  • 25
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane. G protein-coupled receptor
    • Feng, Y., Broder, C. C., Kennedy, P. E., and Berger, E. A. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane. G protein-coupled receptor, Science (Wash. DC), 272: 872-877, 1996.
    • (1996) Science (Wash. DC) , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 27
    • 0028324454 scopus 로고
    • Molecular cloning and structure of a pre-B-cell growth-stimulating factor
    • Nagasawa, T., Kikutani, H., and Kishimoto, T. Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc. Natl. Acad. Sci. USA, 91: 2305-2309, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2305-2309
    • Nagasawa, T.1    Kikutani, H.2    Kishimoto, T.3
  • 28
    • 0031026475 scopus 로고    scopus 로고
    • The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
    • Aiuti, A., Webb, I. J., Bleul, C., Springer, T., and Gutierrez- Ramos, J. C. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J. Exp. Med., 185: 111-120, 1997.
    • (1997) J. Exp. Med. , vol.185 , pp. 111-120
    • Aiuti, A.1    Webb, I.J.2    Bleul, C.3    Springer, T.4    Gutierrez-Ramos, J.C.5
  • 29
    • 0033989027 scopus 로고    scopus 로고
    • Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1
    • Jo, D. Y., Rafii, S., Hamada, T., and Moore, M. A. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1. J Clin Investig., 105: 101-111, 2000.
    • (2000) J Clin Investig. , vol.105 , pp. 101-111
    • Jo, D.Y.1    Rafii, S.2    Hamada, T.3    Moore, M.A.4
  • 31
    • 0035393583 scopus 로고    scopus 로고
    • Epithelial cancer cell migration: A role for chemokine receptors?
    • Scotton, C. J., Wilson, J. L., Milliken, D., Stamp, G., and Balkwill. F. R. Epithelial cancer cell migration: A role for chemokine receptors? Cancer Res., 61: 4961-4965, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 4961-4965
    • Scotton, C.J.1    Wilson, J.L.2    Milliken, D.3    Stamp, G.4    Balkwill, F.R.5
  • 32
    • 0030999238 scopus 로고    scopus 로고
    • Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)
    • Sattler, M., Salgia, R., Shrikhande, G., Verma, S., Pisick, E., Prasad, K. V., and Griffin, J. D. Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL). J. Biol. Chem., 272: 10248-10253, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10248-10253
    • Sattler, M.1    Salgia, R.2    Shrikhande, G.3    Verma, S.4    Pisick, E.5    Prasad, K.V.6    Griffin, J.D.7
  • 35
    • 0032483419 scopus 로고    scopus 로고
    • The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    • Ganju, R. K., Brubaker, S. A., Meyer, J., Dutt, P., Yang, Y., Qin, S., Newman, W., and Groopman, J. E. The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J. Biol. Chem., 273: 23169-23175, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3    Dutt, P.4    Yang, Y.5    Qin, S.6    Newman, W.7    Groopman, J.E.8
  • 37
    • 0034656351 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: Roles of phosphoinositide-3 kinase and protein kinase C
    • Wang, J. F., Park, I. W., and Groopman, J. E. Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: Roles of phosphoinositide-3 kinase and protein kinase C. Blood. 95: 2505-2513, 2000.
    • (2000) Blood , vol.95 , pp. 2505-2513
    • Wang, J.F.1    Park, I.W.2    Groopman, J.E.3
  • 38
    • 0035383788 scopus 로고    scopus 로고
    • Janus kinase 2 is involved in stromal cell-derived factor-1α-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells
    • Zhang, X. F., Wang, J. F., Matczak, E., Proper, J. A., and Groopman, J. E. Janus kinase 2 is involved in stromal cell-derived factor-1α-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood, 97: 3342-3348, 2001.
    • (2001) Blood , vol.97 , pp. 3342-3348
    • Zhang, X.F.1    Wang, J.F.2    Matczak, E.3    Proper, J.A.4    Groopman, J.E.5
  • 39
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke, T. F., Kaplan, D. R., and Cantley, L. C. PI3K: Downstream AKTion blocks apoptosis. Cell, 88: 435-437, 1997.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 40
    • 0030740005 scopus 로고    scopus 로고
    • The modular phosphorylation and activation of p70s6k
    • Pullen, N., and Thomas, G. The modular phosphorylation and activation of p70s6k. FEBS Lett., 410: 78-82, 1997.
    • (1997) FEBS Lett. , vol.410 , pp. 78-82
    • Pullen, N.1    Thomas, G.2
  • 47
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery.
    • Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell, 91: 231-241, 1997.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7


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