Structural and functional basis of CXCL12 (stromal cell-derived factor-1α) binding to heparin

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 10018-10027

  Murphy, James W ^a   Cho, Yoonsang ^a   Sachpatzidis, Aristidis ^a   Fan, Chengpeng ^a   Hodsdon, Michael E ^a   Lolis, Elias ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CELLS; DRUG PRODUCTS; MOLECULAR INTERACTIONS; MOLECULAR STRUCTURE; MUTAGENESIS;

DISACCHARIDES; HEPARAN SULFATE; UNSATURATED HEPARIN;

LIGANDS;

ALANINE; ALPHA CHEMOKINE; ARGININE; ASPARTIC ACID; CHEMOKINE RECEPTOR CXCR4; DIMER; DISACCHARIDE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; HISTIDINE; LYSINE; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CHEMOTAXIS; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; X RAY CRYSTALLOGRAPHY; CHEMISTRY; COMPARATIVE STUDY; DIMERIZATION; GENETICS; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CELL LINE, TUMOR; CHEMOKINES, CXC; CHEMOTAXIS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; GLYCOSAMINOGLYCANS; HEPARIN; HUMANS; PROTEIN BINDING; RECEPTORS, CXCR4;

EID: 34248168879     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608796200     Document Type: Article

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