-
1
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger, E. A., P. M. Murphy, and J. M. Farber. 1999. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17:657-700.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
2
-
-
0037799237
-
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle
-
Blanpain, C., B. J. Doranz, A. Bondne, C. Govaerts, A. De Leener, G. Vassart, R. W. Doms, A. Proudfoot, and M. Parmentier. 2003. The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle. J. Biol. Chem. 278:5179-5187.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5179-5187
-
-
Blanpain, C.1
Doranz, B.J.2
Bondne, A.3
Govaerts, C.4
De Leener, A.5
Vassart, G.6
Doms, R.W.7
Proudfoot, A.8
Parmentier, M.9
-
3
-
-
0029775576
-
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
-
Bleul, C. C., M. Farzan, H. Choe, C. Parolin, I. Clark-Lewis, and J. Sodroski. 1996. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382:829-833.
-
(1996)
Nature
, vol.382
, pp. 829-833
-
-
Bleul, C.C.1
Farzan, M.2
Choe, H.3
Parolin, C.4
Clark-Lewis, I.5
Sodroski, J.6
-
4
-
-
0034604709
-
Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities
-
Brelot, A., N. Heveker, M. Montes, and M. Alizon. 2000. Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities. J. Biol. Chem. 275:23736-23744.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23736-23744
-
-
Brelot, A.1
Heveker, N.2
Montes, M.3
Alizon, M.4
-
5
-
-
0030925290
-
Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity
-
Brelot, A., N. Heveker, O. Pleskoff, N. Sol, and M. Alizon. 1997. Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity. J. Virol. 71:4744-4751.
-
(1997)
J. Virol.
, vol.71
, pp. 4744-4751
-
-
Brelot, A.1
Heveker, N.2
Pleskoff, O.3
Sol, N.4
Alizon, M.5
-
6
-
-
0032768487
-
Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates
-
Chabot, D. J., P. F. Zhang, G. V. Quinnan, and C. C. Broder. 1999. Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates. J. Virol. 73:6598-6609.
-
(1999)
J. Virol.
, vol.73
, pp. 6598-6609
-
-
Chabot, D.J.1
Zhang, P.F.2
Quinnan, G.V.3
Broder, C.C.4
-
7
-
-
0030683638
-
Solution structure and basis for functional activity of stromal cell-derived factor-1: Dissociation of CXCR4 activation from binding and inhibition of HIV-1
-
Crump, M. P., J. H. Gong, P. Loetscher, K. Rajarathnam, A. Amara, F. Arenzana-Seisdedos, J. L. Virelizier, M. Baggiolini, B. D. Sykes, and I. Clark-Lewis. 1997. Solution structure and basis for functional activity of stromal cell-derived factor-1: dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J. 16:6996-7007.
-
(1997)
EMBO J.
, vol.16
, pp. 6996-7007
-
-
Crump, M.P.1
Gong, J.H.2
Loetscher, P.3
Rajarathnam, K.4
Amara, A.5
Arenzana-Seisdedos, F.6
Virelizier, J.L.7
Baggiolini, M.8
Sykes, B.D.9
Clark-Lewis, I.10
-
8
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
Donzella, G. A., D. Schols, S. W. Lin, J. A. Este, K. A. Nagashima, P. J. Maddon, G. P. Allaway, T. P. Sakmar, G. Henson, E. De Clercq, and J. P. Moore. 1998. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat. Med. 4:72-77.
-
(1998)
Nat. Med.
, vol.4
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
Este, J.A.4
Nagashima, K.A.5
Maddon, P.J.6
Allaway, G.P.7
Sakmar, T.P.8
Henson, G.9
De Clercq, E.10
Moore, J.P.11
-
9
-
-
0033050190
-
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
-
Doranz, B., M. Orsini, J. Turner, T. Hoffman, J. Berson, J. Hoxie, S. Peiper, L. Brass, and R. Doms. 1999. Identification of CXCR4 domains that support coreceptor and chemokine receptor functions. J. Virol. 73:2752-2761.
-
(1999)
J. Virol.
, vol.73
, pp. 2752-2761
-
-
Doranz, B.1
Orsini, M.2
Turner, J.3
Hoffman, T.4
Berson, J.5
Hoxie, J.6
Peiper, S.7
Brass, L.8
Doms, R.9
-
10
-
-
0030773515
-
A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor
-
Doranz, B. J., K. Grovit-Ferbas, M. P. Sharron, S. H. Mao, M. B. Goetz, E. S. Daar, R. W. Doms, and W. A. O'Brien. 1997. A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor. J. Exp. Med. 186:1395-1400.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1395-1400
-
-
Doranz, B.J.1
Grovit-Ferbas, K.2
Sharron, M.P.3
Mao, S.H.4
Goetz, M.B.5
Daar, E.S.6
Doms, R.W.7
O'Brien, W.A.8
-
11
-
-
0029805203
-
Host factors and the pathogenesis of HIV-induced disease
-
Fauci, A. S. 1996. Host factors and the pathogenesis of HIV-induced disease. Nature 384:529-534.
-
(1996)
Nature
, vol.384
, pp. 529-534
-
-
Fauci, A.S.1
-
12
-
-
0034915340
-
A peptide derived from bee venom-secreted phospholipase A2 inhibits replication of T-cell tropic HIV-1 strains via interaction with the CXCR4 chemokine receptor
-
Fenard, D., G. Lambeau, T. Maurin, J. C. Lefebvre, and A. Doglio. 2001. A peptide derived from bee venom-secreted phospholipase A2 inhibits replication of T-cell tropic HIV-1 strains via interaction with the CXCR4 chemokine receptor. Mol. Pharmacol. 60:341-347.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 341-347
-
-
Fenard, D.1
Lambeau, G.2
Maurin, T.3
Lefebvre, J.C.4
Doglio, A.5
-
14
-
-
0035423565
-
Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: Implications for development of selective CXCR4 antagonists
-
Gupta, S. K., K. Pillarisetti, R. A. Thomas, and N. Aiyar. 2001. Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists, Immunol. Lett. 78:29-34.
-
(2001)
Immunol. Lett.
, vol.78
, pp. 29-34
-
-
Gupta, S.K.1
Pillarisetti, K.2
Thomas, R.A.3
Aiyar, N.4
-
15
-
-
0029610599
-
Conformational compatibility as a basis of differential affinities of tachykinins for the neurokinin-1 receptor
-
Huang, R. R., D. Huang, C. D. Strader, and T. M. Fong. 1994. Conformational compatibility as a basis of differential affinities of tachykinins for the neurokinin-1 receptor. Biochemistry 34:16467-16472.
-
(1994)
Biochemistry
, vol.34
, pp. 16467-16472
-
-
Huang, R.R.1
Huang, D.2
Strader, C.D.3
Fong, T.M.4
-
16
-
-
0029165752
-
Identification of residues involved in ligand binding to the neurokinin-2 receptor
-
Huaug, R. R., P. P. Vicario, C. D. Strader, and T. M. Fong. 1995. Identification of residues involved in ligand binding to the neurokinin-2 receptor. Biochemistry 34:10048-10055.
-
(1995)
Biochemistry
, vol.34
, pp. 10048-10055
-
-
Huang, R.R.1
Vicario, P.P.2
Strader, C.D.3
Fong, T.M.4
-
17
-
-
0034608195
-
Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4
-
Kajumo, F., D. A. Thompson, V. Guo, and T. Dragic. 2000. Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4. Virology 271:240-247.
-
(2000)
Virology
, vol.271
, pp. 240-247
-
-
Kajumo, F.1
Thompson, D.A.2
Guo, V.3
Dragic, T.4
-
18
-
-
12644288298
-
Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains
-
Lu, Z., J. F. Berson, Y. Chen, J. D. Turner, T. Zhang, M. Sharron, M. H. Jenks, Z. Wang, J. Kim, J. Rucker, J. A. Hoxie, S. C. Peiper, and R. W. Doms. 1997. Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains. Proc. Natl. Acad. Sci. USA 94:6426-6431.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6426-6431
-
-
Lu, Z.1
Berson, J.F.2
Chen, Y.3
Turner, J.D.4
Zhang, T.5
Sharron, M.6
Jenks, M.H.7
Wang, Z.8
Kim, J.9
Rucker, J.10
Hoxie, J.A.11
Peiper, S.C.12
Doms, R.W.13
-
19
-
-
0033938778
-
Molecular characterization of the melanin-concentrating hormone/receptor complex: Identification of critical residues involved in binding and activation
-
Macdonald, D., N. Murgolo, R. Zhang, J. P. Durkin, X. Yao, C. D. Strader, and M. P. Graziano. 2000. Molecular characterization of the melanin-concentrating hormone/receptor complex: identification of critical residues involved in binding and activation. Mol. Pharmacol. 58:217-225.
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 217-225
-
-
Macdonald, D.1
Murgolo, N.2
Zhang, R.3
Durkin, J.P.4
Yao, X.5
Strader, C.D.6
Graziano, M.P.7
-
21
-
-
0028202481
-
The molecular biology of leukocyte chemoattractant receptors
-
Murphy, P. M. 1994. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12:593-633.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 593-633
-
-
Murphy, P.M.1
-
22
-
-
0029758113
-
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
-
Nagasawa, T., S. Hirota, K. Tachibana, N. Takakura, S. Nishikawa, Y. Kitamura, N. Yoshida, H. Kikutani, and T. Kishimoto. 1996. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature 382:635-638.
-
(1996)
Nature
, vol.382
, pp. 635-638
-
-
Nagasawa, T.1
Hirota, S.2
Tachibana, K.3
Takakura, N.4
Nishikawa, S.5
Kitamura, Y.6
Yoshida, N.7
Kikutani, H.8
Kishimoto, T.9
-
23
-
-
0028129959
-
Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation
-
Nussbaum, O., C. C. Broder, and E. A. Berger. 1994. Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation. J. Virol. 68:5411-5422.
-
(1994)
J. Virol.
, vol.68
, pp. 5411-5422
-
-
Nussbaum, O.1
Broder, C.C.2
Berger, E.A.3
-
24
-
-
16044370087
-
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
-
Oberlin, E., A. Amara, F. Bachelerie, C. Bessia, J. L. Virelizier, F. Arenzana-Seisdedos, O. Schwartz, J. M. Heard, I. Clark-Lewis, D. F. Legler, M. Loetscher, M. Baggiolini, and B. Moser. 1996. The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 382:833-835.
-
(1996)
Nature
, vol.382
, pp. 833-835
-
-
Oberlin, E.1
Amara, A.2
Bachelerie, F.3
Bessia, C.4
Virelizier, J.L.5
Arenzana-Seisdedos, F.6
Schwartz, O.7
Heard, J.M.8
Clark-Lewis, I.9
Legler, D.F.10
Loetscher, M.11
Baggiolini, M.12
Moser, B.13
-
25
-
-
0030630237
-
Cell-cell fusion assay to study role of chemokine receptors in human immunodeficiency virus type 1 entry
-
Rucker, J., B. Doranz, A. Edinger, D. Long, J. Berson, and R. Doms. 1997. Cell-cell fusion assay to study role of chemokine receptors in human immunodeficiency virus type 1 entry. Methods Enzymol. 288:118-133.
-
(1997)
Methods Enzymol.
, vol.288
, pp. 118-133
-
-
Rucker, J.1
Doranz, B.2
Edinger, A.3
Long, D.4
Berson, J.5
Doms, R.6
-
26
-
-
0037428443
-
Identification of allosteric peptide agonists of CXCR4
-
Sachpatzidis, A., B. K. Benton, J. P. Manfredi, H. Wang, A. Hamilton, H. G. Dohlman, and E. Lolis. 2003. Identification of allosteric peptide agonists of CXCR4. J. Biol. Chem. 278:896-907.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 896-907
-
-
Sachpatzidis, A.1
Benton, B.K.2
Manfredi, J.P.3
Wang, H.4
Hamilton, A.5
Dohlman, H.G.6
Lolis, E.7
-
27
-
-
0028289513
-
Structure and function of G protein-coupled receptors
-
Strader, C. D., T. M. Fong, M. R. Tota, and D. Underwood. 1994. Structure and function of G protein-coupled receptors. Annu. Rev. Biochem. 63:101-132.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 101-132
-
-
Strader, C.D.1
Fong, T.M.2
Tota, M.R.3
Underwood, D.4
-
28
-
-
0032508033
-
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
-
Tachibana, K., S. Hirota, H. Iizasa, H. Yoshida, K. Kawahata, Y. Kataoka, Y. Kitamura, K. Matsushima, N. Yoshida, S. Nishikawa, T. Kishimoto, and T. Nagasawa. 1998. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393:591-594.
-
(1998)
Nature
, vol.393
, pp. 591-594
-
-
Tachibana, K.1
Hirota, S.2
Iizasa, H.3
Yoshida, H.4
Kawahata, K.5
Kataoka, Y.6
Kitamura, Y.7
Matsushima, K.8
Yoshida, N.9
Nishikawa, S.10
Kishimoto, T.11
Nagasawa, T.12
-
29
-
-
0028575843
-
Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex
-
Wild, C., J. W. Dubay, T. Greenwell, T. J. Baird, T. C. Oas, C. McDanal, E. Hunter, and T. Matthews. 1994. Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex. Proc. Natl. Acad. Sci. USA 91:12676-12680.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12676-12680
-
-
Wild, C.1
Dubay, J.W.2
Greenwell, T.3
Baird, T.J.4
Oas, T.C.5
McDanal, C.6
Hunter, E.7
Matthews, T.8
-
30
-
-
0027959493
-
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
-
Wild, C. T., D. C. Shugars, T. K. Greenwell, C. B. McDanal, and T. J. Matthews. 1994. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. Proc. Natl. Acad. Sci. USA 91:9770-9774.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9770-9774
-
-
Wild, C.T.1
Shugars, D.C.2
Greenwell, T.K.3
McDanal, C.B.4
Matthews, T.J.5
-
31
-
-
0037124101
-
Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines
-
Zhou, N., Z. Luo, J. Luo, X. Fan, M. Cayabyab, M. Hiraoka, D. Liu, X. Han, J. Pesavento, C. Z. Dong, Y. Wang, J. An, H. Kaji, J. G. Sodroski, and Z. Huang. 2002. Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines. J. Biol. Chem. 277:17476-17485.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17476-17485
-
-
Zhou, N.1
Luo, Z.2
Luo, J.3
Fan, X.4
Cayabyab, M.5
Hiraoka, M.6
Liu, D.7
Han, X.8
Pesavento, J.9
Dong, C.Z.10
Wang, Y.11
An, J.12
Kaji, H.13
Sodroski, J.G.14
Huang, Z.15
-
32
-
-
0034603860
-
A novel peptide antagonist of CXCR4 derived from the N-terminus of the viral chemokine vMIP-II
-
Zhou, N., Z. Luo, J. Luo, J. W. Hall, and Z. Huang. 2000. A novel peptide antagonist of CXCR4 derived from the N-terminus of the viral chemokine vMIP-II. Biochemistry 39:3782-3787.
-
(2000)
Biochemistry
, vol.39
, pp. 3782-3787
-
-
Zhou, N.1
Luo, Z.2
Luo, J.3
Hall, J.W.4
Huang, Z.5
-
33
-
-
0035900771
-
Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies
-
Zhou, N., Z. Luo, J. Luo, D. Liu, J. W. Hall, R. J. Pomerantz, and Z. Huang. 2001. Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies. J. Biol. Chem. 276:42826-42833.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42826-42833
-
-
Zhou, N.1
Luo, Z.2
Luo, J.3
Liu, D.4
Hall, J.W.5
Pomerantz, R.J.6
Huang, Z.7
-
34
-
-
0032507962
-
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
-
Zou, Y., A. Kottmann, M. Kuroda, I. Taniuchi, and D. Littman. 1998. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393:595-599.
-
(1998)
Nature
, vol.393
, pp. 595-599
-
-
Zou, Y.1
Kottmann, A.2
Kuroda, M.3
Taniuchi, I.4
Littman, D.5
|