Influence of oligospermines architecture on their suitability for siRNA delivery

Biomacromolecules

Volumn 15, Issue 4, 2014, Pages 1299-1310

  Elsayed, Maha ^a   Corrand, Vincent ^a   Kolhatkar, Vidula ^b   Xie, Yuran ^a   Kim, Na Hyung ^a   Kolhatkar, Rohit ^b   Merkel, Olivia M ^a,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c KARMANOS CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; CELL CULTURE; EFFICIENCY; GENE EXPRESSION; RNA;

ACIDIC ENVIRONMENT; LOW MOLECULAR WEIGHT; MOLECULAR ARCHITECTURE; NON-SMALL CELL LUNG CARCINOMATA; NONVIRAL VECTORS; POLYETHYLENIMINES; PROTEIN EXPRESSION LEVELS; STRUCTURE ACTIVITY RELATIONSHIPS;

ARCHITECTURE;

DENDRITIC TETRASPERMINE; HEPARIN; LINEAR BISSPERMINE; LINEAR TETRASPERMINE; POLYANION; POLYETHYLENEIMINE; POLYMER; SMALL INTERFERING RNA; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG; ANION; SPERMINE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CANCER CELL CULTURE; CELL MEMBRANE; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENDOSOME; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDRODYNAMICS; LUNG NON SMALL CELL CANCER; MOLECULAR WEIGHT; MTT ASSAY; NOMENCLATURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; STATIC ELECTRICITY; STRUCTURE ACTIVITY RELATION; SURFACE CHARGE; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; GENE VECTOR; GENETICS; LUNG TUMOR; METABOLISM; NON SMALL CELL LUNG CANCER; PHARMACOKINETICS; TOXICITY; TOXICITY TESTING;

ANIONS; BINDING, COMPETITIVE; CARCINOMA, NON-SMALL-CELL LUNG; CHEMISTRY TECHNIQUES, SYNTHETIC; FLOW CYTOMETRY; GENE KNOCKDOWN TECHNIQUES; GENETIC VECTORS; HEPARIN; HUMANS; LUNG NEOPLASMS; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR STRUCTURE; RNA, SMALL INTERFERING; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TOXICITY TESTS;

EID: 84898611826     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm401849d     Document Type: Article

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