Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates

Biomaterials

Volumn 27, Issue 8, 2006, Pages 1646-1655

  Eliyahu, Hagit ^a,b   Siani, Shahar ^a   Azzam, Tony ^b   Domb, Abraham J ^b   Barenholz, Yechezkel ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Dextran; Fluorescence; Gene delivery; Proton sponge

Indexed keywords

AMINO ACIDS; BIODEGRADATION; COMPOSITION; DEXTROSE; FLUORESCENCE; NUCLEIC ACIDS; OXIDATION; PH EFFECTS; SYNTHESIS (CHEMICAL);

GENE DELIVERY; POLYSACCHARIDE-SPERMINE CONJUGATES; PROTON SPONGE; TRANSFECTION EFFICIENCY;

POLYSACCHARIDES;

AMINO ACID DERIVATIVE; ARABINOGALACTAN; DEXTRAN; N OLEYL DEXTRAN SPERMINE; NITROGEN; NUCLEIC ACID; PLASMID DNA; POLYCATION; POLYSACCHARIDE; SPERMINE; SPERMINE DERIVATIVE; UMBELLIFERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHEMICAL BOND; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONJUGATE; CONJUGATION; CONTROLLED STUDY; CROSS LINKING; ENDOSOME; GENETIC TRANSFECTION; MOUSE; NONHUMAN; OXIDATION KINETICS; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURFACE CHARGE; SURFACE PROPERTY; TITRIMETRY; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; DNA; ELECTROSTATICS; KINETICS; MICE; NIH 3T3 CELLS; PLASMIDS; POLYAMINES; POLYSACCHARIDES; SPERMINE; THERMODYNAMICS; TRANSFECTION;

ANIMALIA;

EID: 28444448090     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2005.09.005     Document Type: Article

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