Novel cholesterol spermine conjugates provide efficient cellular delivery of plasmid DNA and small interfering RNA

Journal of Controlled Release

Volumn 160, Issue 2, 2012, Pages 182-193

  Maslov, Mikhail A ^a   Kabilova, Tatyana O ^b   Petukhov, Ivan A ^a   Morozova, Nina G ^a   Serebrennikova, Galina A ^a   Vlassov, Valentine V ^b   Zenkova, Marina A ^b  

^a MIREA RUSSIAN TECHNOLOGICAL UNIVERSITY   (Russian Federation)

^b INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

Cationic lipids; Gemini surfactants; Liposomes; Non viral delivery system; siRNA; Transfection

Indexed keywords

CATIONIC LIPIDS; DELIVERY SYSTEMS; GEMINI SURFACTANT; SIRNA; TRANSFECTION;

BIOMOLECULES; CATIONIC SURFACTANTS; CHOLESTEROL; COMPLEXATION; DYES; GENE TRANSFER; LIPOSOMES; OLIGONUCLEOTIDES; RNA;

LIPIDS;

AMPHOPHILE; CARBAMIC ACID; CARBENE; CHOLESTEROL; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; ENHANCED GREEN FLUORESCENT PROTEIN; ESTER; FLUORESCEIN ISOTHIOCYANATE; LIPID; LIPOFECTAMINE; LIPOSOME; NUCLEIC ACID; OLIGONUCLEOTIDE; PLASMID DNA; POLYAMINE; POLYCATION; SMALL INTERFERING RNA; SPERMINE;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ZETA POTENTIAL;

ANIMALS; CELL SURVIVAL; CHOLESTEROL; CRICETINAE; DNA; DRUG CARRIERS; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; LIPOSOMES; MOLECULAR STRUCTURE; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; RNA, SMALL INTERFERING; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 84861678053     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.023     Document Type: Article

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