-
1
-
-
0029030051
-
Medical aerosol inhalers: Past, present, and future
-
Clark A. - Medical aerosol inhalers: past, present, and future. - Aerosol Sci. Technol., 22, 374-391, 1995.
-
(1995)
Aerosol Sci. Technol.
, vol.22
, pp. 374-391
-
-
Clark, A.1
-
2
-
-
33645034817
-
Nanoencapsulation. I. Methods for preparation of drug-loaded polymeric nanoparticles
-
Pinto Reis C., Neufeld R., Ribeiro A., Veiga F. - Nanoencapsulation. I. Methods for preparation of drug-loaded polymeric nanoparticles. - Nanomedicine, 2, 8-21, 2006.
-
(2006)
Nanomedicine
, vol.2
, pp. 8-21
-
-
Pinto Reis, C.1
Neufeld, R.2
Ribeiro, A.3
Veiga, F.4
-
3
-
-
42049094490
-
Pharmaceutical particle engineering via spray drying
-
Vehring R. - Pharmaceutical particle engineering via spray drying. - Pharm. Res., 25, 999-1022, 2008.
-
(2008)
Pharm. Res.
, vol.25
, pp. 999-1022
-
-
Vehring, R.1
-
4
-
-
20444459212
-
Pegylated poly(lactide) and poly(lactide-coglycolide) nanoparticles: Preparation, properties and possible applications in drug delivery
-
Avgoustakis K. - Pegylated poly(lactide) and poly(lactide-coglycolide) nanoparticles: preparation, properties and possible applications in drug delivery. - Curr. Drug Delivery, 1, 321-333, 2004.
-
(2004)
Curr. Drug Delivery
, vol.1
, pp. 321-333
-
-
Avgoustakis, K.1
-
5
-
-
55649104973
-
Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles
-
Wischke C., Schwendeman S. - Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles. - Int. J. Pharm., 364, 298-327, 2008.
-
(2008)
Int. J. Pharm.
, vol.364
, pp. 298-327
-
-
Wischke, C.1
Schwendeman, S.2
-
6
-
-
0032901219
-
Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method
-
Barichello J.M., Morishita M., Takayama K., Nagai T. - Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method. - Drug Dev. Ind. Pharm., 25, 471-476, 1999.
-
(1999)
Drug Dev. Ind. Pharm.
, vol.25
, pp. 471-476
-
-
Barichello, J.M.1
Morishita, M.2
Takayama, K.3
Nagai, T.4
-
8
-
-
0026813472
-
Allometric relationships of cell numbers and size in the mammalian lung
-
Stone K., Mercer R., Gehr P., Stockstill B., Crapo J. - Allometric relationships of cell numbers and size in the mammalian lung. - Am. J. Respir. Cell Mol. Biol., 6, 235, 1992.
-
(1992)
Am. J. Respir. Cell Mol. Biol.
, vol.6
, pp. 235
-
-
Stone, K.1
Mercer, R.2
Gehr, P.3
Stockstill, B.4
Crapo, J.5
-
9
-
-
0022889862
-
DEPOSITION of PARTICLES in the HUMAN RESPIRATORY TRACT in the SIZE RANGE 0. 005-15 mu m
-
DOI 10.1016/0021-8502(86)90035-2
-
Heyder J., Gebhart J., Rudolf G., Schiller C., Stahlofen W. - Deposition of particles in the human respiratory tract in the size range 0, 005-15 m. - J. Aerosol. Sci., 17, 811-825, 1986. (Pubitemid 17492310)
-
(1986)
Journal of Aerosol Science
, vol.17
, Issue.5
, pp. 811-825
-
-
Heyder, J.1
Gebhart, J.2
Rudolf, G.3
Schiller, C.F.4
Stahlhofen, W.5
-
10
-
-
0027937427
-
The new ICRP model for the respiratory tract
-
Bailey M.R. - The new ICRP model for the respiratory tract. - Radiat. Prot. Dosim., 53, 107-114, 1994.
-
(1994)
Radiat. Prot. Dosim.
, vol.53
, pp. 107-114
-
-
Bailey, M.R.1
-
11
-
-
60849111087
-
Airway mucus: The good, the bad, the sticky
-
Evans C., Koo J. - Airway mucus: the good, the bad, the sticky. - Pharmacol. Ther., 121, 332-348, 2009.
-
(2009)
Pharmacol. Ther.
, vol.121
, pp. 332-348
-
-
Evans, C.1
Koo, J.2
-
12
-
-
33847127477
-
Particle engineering for pulmonary drug delivery
-
Chow A., Tong H., Chattopadhyay P., Shekunov B. - Particle engineering for pulmonary drug delivery. - Pharm. Res., 24, 411-437, 2007.
-
(2007)
Pharm. Res.
, vol.24
, pp. 411-437
-
-
Chow, A.1
Tong, H.2
Chattopadhyay, P.3
Shekunov, B.4
-
13
-
-
33845906339
-
Inhaling medicines: Delivering drugs to the body through the lungs
-
Patton J., Byron R - Inhaling medicines: delivering drugs to the body through the lungs. - Nat. Rev. Drug Discov., 6, 67-74, 2007.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 67-74
-
-
Patton, J.1
Byron, R.2
-
14
-
-
45949097539
-
Inhaled prostanoids in the therapy of pulmonary hypertension
-
Gessler T., Seeger W., Schmehl T. - Inhaled prostanoids in the therapy of pulmonary hypertension. - J. Aerosol Med. Pulm. Drug Deliv., 21, 1-12, 2008.
-
(2008)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.21
, pp. 1-12
-
-
Gessler, T.1
Seeger, W.2
Schmehl, T.3
-
15
-
-
10044290890
-
The role of branched polyesters and their modifications in the development of modern drug delivery vehicles
-
Dailey L., Wittmar M., Kissel T. - The role of branched polyesters and their modifications in the development of modern drug delivery vehicles. - J. Control. Rel., 101, 137-149, 2005.
-
(2005)
J. Control. Rel.
, vol.101
, pp. 137-149
-
-
Dailey, L.1
Wittmar, M.2
Kissel, T.3
-
16
-
-
47349122617
-
Biodegradable polymeric nanocarriers for pulmonary drug delivery
-
Rytting E., Nguyen J., Wang X., Kissel T. - Biodegradable polymeric nanocarriers for pulmonary drug delivery. - Expert Opin. Drug Deliv., 5, 629-639, 2008.
-
(2008)
Expert Opin. Drug Deliv.
, vol.5
, pp. 629-639
-
-
Rytting, E.1
Nguyen, J.2
Wang, X.3
Kissel, T.4
-
17
-
-
47949094123
-
The surface characterisation and comparison of two potential sub-micron, sugar bulking excipients for use in low-dose, suspension formulations in metered dose inhalers
-
James J., Crean B., Davies M., Toon R., Jinks P., Roberts C. - The surface characterisation and comparison of two potential sub-micron, sugar bulking excipients for use in low-dose, suspension formulations in metered dose inhalers. - Int. J. Pharm., 361, 209-221, 2008.
-
(2008)
Int. J. Pharm.
, vol.361
, pp. 209-221
-
-
James, J.1
Crean, B.2
Davies, M.3
Toon, R.4
Jinks, P.5
Roberts, C.6
-
18
-
-
57749181307
-
Templated open flocs of nanorods for enhanced pulmonary delivery with pressurized metered dose inhalers
-
Engstrom J., Tam J., Miller M., Williams R., Johnston K. -Templated open flocs of nanorods for enhanced pulmonary delivery with pressurized metered dose inhalers. - Pharm. Res., 26, 101-117, 2009.
-
(2009)
Pharm. Res.
, vol.26
, pp. 101-117
-
-
Engstrom, J.1
Tam, J.2
Miller, M.3
Williams, R.4
Johnston, K.5
-
19
-
-
67349241928
-
Insulin nanoparticles: Stability and aerosolization from pressurized metered dose inhalers
-
Nyambura B.K., Kellaway I.W., Taylor K.M.G. - Insulin nanoparticles: stability and aerosolization from pressurized metered dose inhalers. - Int. J. Pharm., 375, 114-122, 2009.
-
(2009)
Int. J. Pharm.
, vol.375
, pp. 114-122
-
-
Nyambura, B.K.1
Kellaway, I.W.2
Taylor, K.M.G.3
-
20
-
-
64149116680
-
The processing of nanoparticles containing protein for suspension in hydrofluoroalkane propellents
-
Nyambura B.K., Kellaway I.W., Taylor K.M.G. - The processing of nanoparticles containing protein for suspension in hydrofluoroalkane propellents. - Int. J. Pharm., 372, 140-146, 2009.
-
(2009)
Int. J. Pharm.
, vol.372
, pp. 140-146
-
-
Nyambura, B.K.1
Kellaway, I.W.2
Taylor, K.M.G.3
-
21
-
-
0343407048
-
Spray-drying of solid lipid nanoparticles (SLN(TM))
-
DOI 10.1016/S0939-6411(97)00172-0, PII S0939641197001720
-
Freitas C., Müller R. - Spray-drying of Solid Lipid Nanoparticles (SLN™) - Eur. J. Pharm. Biopharm., 46, 145-151, 1998. (Pubitemid 28414472)
-
(1998)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.46
, Issue.2
, pp. 145-151
-
-
Freitas, C.1
Muller, R.H.2
-
22
-
-
0347360189
-
Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung
-
Sham J.O.H., Zhang Y., Finlay W.H., Roa W.H., Lobenberg R. - Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung. - Int. J. Pharm., 269, 457-467, 2004.
-
(2004)
Int. J. Pharm.
, vol.269
, pp. 457-467
-
-
Sham, J.O.H.1
Zhang, Y.2
Finlay, W.H.3
Roa, W.H.4
Lobenberg, R.5
-
23
-
-
33846496876
-
Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterisation
-
Tewa-Tagne P., Briançon S., Fessi H. - Preparation of redispersible dry nanocapsules by means of spray-drying: development and characterisation. - Eur. J. Pharm. Sci., 30, 124-135, 2007.
-
(2007)
Eur. J. Pharm. Sci.
, vol.30
, pp. 124-135
-
-
Tewa-Tagne, P.1
Briançon, S.2
Fessi, H.3
-
24
-
-
34547554369
-
Engineering of poly (DL-lactic-co-glycolic acid) nanocomposite particles for dry powder inhalation dosage forms of insulin with the spray-fluidized bed granulating system
-
Yamamoto H., Hoshina W., Kurashima H., Takeuchi H., Kawashima Y., Yokoyama T., Tsujimoto H. - Engineering of poly (DL-lactic-co-glycolic acid) nanocomposite particles for dry powder inhalation dosage forms of insulin with the spray-fluidized bed granulating system. - Adv. Powder Technol., 18, 215-228, 2007.
-
(2007)
Adv. Powder Technol.
, vol.18
, pp. 215-228
-
-
Yamamoto, H.1
Hoshina, W.2
Kurashima, H.3
Takeuchi, H.4
Kawashima, Y.5
Yokoyama, T.6
Tsujimoto, H.7
-
25
-
-
0037426696
-
Nebulization of biodegradable nanoparticles: Impact of nebulizer technology and nanoparticle characteristics on aerosol features
-
Dailey L.A., Schmehl T., Gessler T., Wittmar M., Grimminger F., Seeger W., Kissel T. - Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. - J. Control. Rel., 86, 131-144, 2003.
-
(2003)
J. Control. Rel.
, vol.86
, pp. 131-144
-
-
Dailey, L.A.1
Schmehl, T.2
Gessler, T.3
Wittmar, M.4
Grimminger, F.5
Seeger, W.6
Kissel, T.7
-
26
-
-
57749177461
-
Stabilization of aerosolizable nano-carriers by freeze-drying
-
Packhaeuser C., Lahnstein K., Sitterberg J., Schmehl T., Gessler T., Bakowsky U., Seeger W., Kissel T. - Stabilization of aerosolizable nano-carriers by freeze-drying. - Pharm. Res., 26, 129-138, 2009.
-
(2009)
Pharm. Res.
, vol.26
, pp. 129-138
-
-
Packhaeuser, C.1
Lahnstein, K.2
Sitterberg, J.3
Schmehl, T.4
Gessler, T.5
Bakowsky, U.6
Seeger, W.7
Kissel, T.8
-
27
-
-
23744500104
-
Cystic fibrosis: Disease mechanisms and therapeutic targets
-
McKone E., Aitken M. - Cystic fibrosis: disease mechanisms and therapeutic targets. - Drug Discov. Today Dis. Mech., 1, 137-143, 2004.
-
(2004)
Drug Discov. Today Dis. Mech.
, vol.1
, pp. 137-143
-
-
McKone, E.1
Aitken, M.2
-
28
-
-
34249662628
-
Cystic fibrosis: A disease of vulnerability to airway surface dehydration
-
Boucher R. - Cystic fibrosis: a disease of vulnerability to airway surface dehydration. - Trends Mol. Med, 13, 231-240, 2007.
-
(2007)
Trends Mol. Med
, vol.13
, pp. 231-240
-
-
Boucher, R.1
-
29
-
-
60149110687
-
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles
-
Suk J., Lai S., Wang Y., Ensign L., Zeitlin P., Boyle M., Hanes J. - The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles. - Biomaterials, 30, 2591-2597, 2009.
-
(2009)
Biomaterials
, vol.30
, pp. 2591-2597
-
-
Suk, J.1
Lai, S.2
Wang, Y.3
Ensign, L.4
Zeitlin, P.5
Boyle, M.6
Hanes, J.7
-
30
-
-
73349140554
-
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
-
Tang B., Dawson M., Lai S., Wang Y., Suk J., Yang M., Zeitlin P., Boyle M., Fu J., Hanes J. - Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. - Proc. Nat. Acad. Sci., 106, 19268-19273, 2009.
-
(2009)
Proc. Nat. Acad. Sci.
, vol.106
, pp. 19268-19273
-
-
Tang, B.1
Dawson, M.2
Lai, S.3
Wang, Y.4
Suk, J.5
Yang, M.6
Zeitlin, P.7
Boyle, M.8
Fu, J.9
Hanes, J.10
-
31
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
Bateman E., Hurd S., Barnes P., Bousquet J., Drazen J., FitzGerald M., Gibson P., Ohta K., O'Byrne P., Pedersen S. - Global strategy for asthma management and prevention: GINA executive summary. - Eur. Resp. J., 31, 143, 2008.
-
(2008)
Eur. Resp. J.
, vol.31
, pp. 143
-
-
Bateman, E.1
Hurd, S.2
Barnes, P.3
Bousquet, J.4
Drazen, J.5
Fitzgerald, M.6
Gibson, P.7
Ohta, K.8
O'Byrne, P.9
Pedersen, S.10
-
32
-
-
35349012074
-
The use of household cleaning sprays and adult asthma: An international longitudinal study
-
Zock J.-P., Plana E., Jarvis D., Anto J.M., Kromhout H., Kennedy S.M., Kunzli N., Villani S., Olivieri M., Toren K., Radon K., Sunyer J., Dahlman-Hoglund A., Norback D., Kogevinas M. - The use of household cleaning sprays and adult asthma: an international longitudinal study. - Am. J. Respir. Crit. Care Med., 176, 735-741, 2007.
-
(2007)
Am. J. Respir. Crit. Care Med.
, vol.176
, pp. 735-741
-
-
Zock, J.-P.1
Plana, E.2
Jarvis, D.3
Anto, J.M.4
Kromhout, H.5
Kennedy, S.M.6
Kunzli, N.7
Villani, S.8
Olivieri, M.9
Toren, K.10
Radon, K.11
Sunyer, J.12
Dahlman-Hoglund, A.13
Norback, D.14
Kogevinas, M.15
-
33
-
-
1842552109
-
Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper
-
Celli B., MacNee W., Agusti A., Anzueto A., Berg B., Buist A., Calverley P., Chavannes N., Dillard T., Fahy B. - Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. - Eur. Resp. J., 23, 932-946, 2004.
-
(2004)
Eur. Resp. J.
, vol.23
, pp. 932-946
-
-
Celli, B.1
MacNee, W.2
Agusti, A.3
Anzueto, A.4
Berg, B.5
Buist, A.6
Calverley, P.7
Chavannes, N.8
Dillard, T.9
Fahy, B.10
-
34
-
-
34447530157
-
Chronic obstructive pulmonary disease: Histopathology, inflammation and potential therapies
-
Molfino N., Jeffery P. - Chronic obstructive pulmonary disease: histopathology, inflammation and potential therapies. - Pulm. Pharmacol. Ther., 20, 462-472, 2007.
-
(2007)
Pulm. Pharmacol. Ther.
, vol.20
, pp. 462-472
-
-
Molfino, N.1
Jeffery, P.2
-
35
-
-
47049104141
-
Drugs (including oxygen) in severe COPD
-
Albert P., Calverley P. - Drugs (including oxygen) in severe COPD. - Eur. Resp. J., 31, 1114, 2008.
-
(2008)
Eur. Resp. J.
, vol.31
, pp. 1114
-
-
Albert, P.1
Calverley, P.2
-
36
-
-
70849084242
-
In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles
-
Rytting E., Bur M., Cartier R., Bouyssou T., Wang X., Krüger M., Lehr C.-M., Kissel T. - In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles - J. Control. Rel., 141, 101-107, 2009.
-
(2009)
J. Control. Rel.
, vol.141
, pp. 101-107
-
-
Rytting, E.1
Bur, M.2
Cartier, R.3
Bouyssou, T.4
Wang, X.5
Krüger, M.6
Lehr, C.-M.7
Kissel, T.8
-
37
-
-
76649145422
-
Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles
-
Beck-Broichsitter M., Gauss J., Gessler T., Seeger W., Kissel T., Schmehl T. - Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles. - J. Aerosol Med. Pulm. Drug Deliv., 23, 47-57, 2010.
-
(2010)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.23
, pp. 47-57
-
-
Beck-Broichsitter, M.1
Gauss, J.2
Gessler, T.3
Seeger, W.4
Kissel, T.5
Schmehl, T.6
-
38
-
-
67349147683
-
Global tuberculosis control: Epidemiology, strategy, financing
-
World Health Organization. Publication No. WHO/HTM/TB/2009.411, Geneva
-
World Health Organization. - Global tuberculosis control: epidemiology, strategy, financing: WHO report 2009. - Publication No. WHO/HTM/TB/2009.411, Geneva, 2009.
-
(2009)
WHO Report 2009
-
-
-
39
-
-
0347519282
-
Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis
-
Pandey R., Sharma A., Zahoor A., Sharma S., Khuller G.K., Prasad B. - Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis. - J. Antimicrob. Chemother., 52, 981-986, 2003.
-
(2003)
J. Antimicrob. Chemother.
, vol.52
, pp. 981-986
-
-
Pandey, R.1
Sharma, A.2
Zahoor, A.3
Sharma, S.4
Khuller, G.K.5
Prasad, B.6
-
40
-
-
34948817275
-
New molecularly targeted therapies for lung cancer
-
Sun S., Schiller J.H., Spinola M., Minna J.D. - New molecularly targeted therapies for lung cancer. - J. Clin. Invest., 117, 2740-2750, 2007.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2740-2750
-
-
Sun, S.1
Schiller, J.H.2
Spinola, M.3
Minna, J.D.4
-
41
-
-
34547672749
-
Targeted delivery of magnetic aerosol droplets to the lung
-
Dames P., Gleich B., Flemmer A., Hajek K., Seidl N., Wiekhorst F., Eberbeck D., Bittmann I., Bergemann C., Weyh T., Trahms L., Rosenecker J., Rudolph C. - Targeted delivery of magnetic aerosol droplets to the lung. - Nat. Nanotechnol., 2, 495-499, 2007.
-
(2007)
Nat. Nanotechnol.
, vol.2
, pp. 495-499
-
-
Dames, P.1
Gleich, B.2
Flemmer, A.3
Hajek, K.4
Seidl, N.5
Wiekhorst, F.6
Eberbeck, D.7
Bittmann, I.8
Bergemann, C.9
Weyh, T.10
Trahms, L.11
Rosenecker, J.12
Rudolph, C.13
-
42
-
-
41949104810
-
Pulmonary arterial hypertension
-
Chin K.M., Rubin L.J. - Pulmonary arterial hypertension. - J. Am. Coll. Cardiol., 51, 1527-1538, 2008.
-
(2008)
J. Am. Coll. Cardiol.
, vol.51
, pp. 1527-1538
-
-
Chin, K.M.1
Rubin, L.J.2
-
43
-
-
67649970063
-
Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases
-
Smola M., Vandamme T., Sokolowski A. - Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases. - Int. J. Nanomed., 3, 1-19, 2008.
-
(2008)
Int. J. Nanomed.
, vol.3
, pp. 1-19
-
-
Smola, M.1
Vandamme, T.2
Sokolowski, A.3
-
44
-
-
0023753559
-
Long-lasting effects of tobacco smoking on pulmonary drug-metabolizing enzymes: A case-control study on lung cancer patients
-
Petruzzelli S., Camus A.-M., Carrozzi L., Ghelarducci L., Rindi M., Menconi G., Angeletti C.A., Ahotupa M., Hietanen E., Aitio A., Saracci R., Bartsch H., Giuntini C. - Long-lasting effects of tobacco smoking on pulmonary drug-metabolizing enzymes: a case-control study on lung cancer patients. - Cancer Res., 48, 4695-4700, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 4695-4700
-
-
Petruzzelli, S.1
Camus, A.-M.2
Carrozzi, L.3
Ghelarducci, L.4
Rindi, M.5
Menconi, G.6
Angeletti, C.A.7
Ahotupa, M.8
Hietanen, E.9
Aitio, A.10
Saracci, R.11
Bartsch, H.12
Giuntini, C.13
-
45
-
-
33750845387
-
In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery
-
Sakagami M. - In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery. - Adv. Drug Deliv. Rev., 58, 1030-1060, 2006.
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 1030-1060
-
-
Sakagami, M.1
-
46
-
-
0028306077
-
Adult respiratory distress syndrome: Model systems using isolated perfused rabbit lungs
-
Seeger W., Walmrath D., Grimminger F., Rosseau S., Schütte H., Krämer H., Ermert L., Kiss L. - Adult respiratory distress syndrome: model systems using isolated perfused rabbit lungs. - Methods Enzymol., 233, 549-584, 1994.
-
(1994)
Methods Enzymol.
, vol.233
, pp. 549-584
-
-
Seeger, W.1
Walmrath, D.2
Grimminger, F.3
Rosseau, S.4
Schütte, H.5
Krämer, H.6
Ermert, L.7
Kiss, L.8
-
47
-
-
58249113936
-
Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model
-
Beck-Broichsitter M., Gauss J., Packhaeuser C., Lahnstein K., Schmehl T., Seeger W., Kissel T., Gessler T. - Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model. - Int. J. Pharm., 367, 169-178, 2009.
-
(2009)
Int. J. Pharm.
, vol.367
, pp. 169-178
-
-
Beck-Broichsitter, M.1
Gauss, J.2
Packhaeuser, C.3
Lahnstein, K.4
Schmehl, T.5
Seeger, W.6
Kissel, T.7
Gessler, T.8
-
48
-
-
70350183750
-
Influence of perfusate composition on drug disposition in the in situ perfused rat lung
-
Liu X., Wang J.Y., Khlentzos A.M., Fontaine F., Nikolovski J., Goh L.-A., Roberts M.S. - Influence of perfusate composition on drug disposition in the in situ perfused rat lung. - Int. J. Pharm., 382, 192-197, 2009.
-
(2009)
Int. J. Pharm.
, vol.382
, pp. 192-197
-
-
Liu, X.1
Wang, J.Y.2
Khlentzos, A.M.3
Fontaine, F.4
Nikolovski, J.5
Goh, L.-A.6
Roberts, M.S.7
-
49
-
-
70450221930
-
Biodegradable polymeric nanoparticles based drug delivery systems
-
Kumari A., Yadav S.K., Yadav S.C. - Biodegradable polymeric nanoparticles based drug delivery systems. - Colloid Surf. B-Biointerfaces, 75, 1-18, 2009.
-
(2009)
Colloid Surf. B-Biointerfaces
, vol.75
, pp. 1-18
-
-
Kumari, A.1
Yadav, S.K.2
Yadav, S.C.3
-
50
-
-
0343247711
-
Biodegradation and biocompatibility of PLA and PLGA microspheres
-
Anderson J., Shive M. - Biodegradation and biocompatibility of PLA and PLGA microspheres. - Adv. Drug Deliv. Rev., 28, 5-24, 1997.
-
(1997)
Adv. Drug Deliv. Rev.
, vol.28
, pp. 5-24
-
-
Anderson, J.1
Shive, M.2
-
51
-
-
66049113578
-
Quantifying drug release from PLGA nanoparticulates
-
Corrigan O., Li X. - Quantifying drug release from PLGA nanoparticulates. - Eur. J. Pharm. Sci., 37, 477-485, 2009.
-
(2009)
Eur. J. Pharm. Sci.
, vol.37
, pp. 477-485
-
-
Corrigan, O.1
Li, X.2
-
52
-
-
0141853257
-
Polymer degradation and in vitro release of a model protein from poly(lactide-co-glycolide) nano- And microparticles
-
Panyam J., Dali M.M., Sahoo S.K., Ma W., Chakravarthi S.S., Amidon G.L., Levy R.J., Labhasetwar V. - Polymer degradation and in vitro release of a model protein from poly(lactide-co-glycolide) nano- and microparticles - J. Control. Rel., 92, 173-187, 2003.
-
(2003)
J. Control. Rel.
, vol.92
, pp. 173-187
-
-
Panyam, J.1
Dali, M.M.2
Sahoo, S.K.3
Ma, W.4
Chakravarthi, S.S.5
Amidon, G.L.6
Levy, R.J.7
Labhasetwar, V.8
-
53
-
-
40049094540
-
Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate- co-vinyl acetate-co-vinyl alcohol]-graft-poly(d,l-lactide-co-glycolide): Effects of polymer structure on in vitro degradation behaviour
-
Unger F., Wittmar M., Morell F., Kissel T. - Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(d,l-lactide-co-glycolide): effects of polymer structure on in vitro degradation behaviour. - Biomaterials, 29, 2007-2014, 2008.
-
(2008)
Biomaterials
, vol.29
, pp. 2007-2014
-
-
Unger, F.1
Wittmar, M.2
Morell, F.3
Kissel, T.4
-
54
-
-
0028127992
-
Influence of enzymes on the stability of polybutylcyanoacrylate nanoparticles
-
Scherer D., Robinson J.R., Kreuter J. - Influence of enzymes on the stability of polybutylcyanoacrylate nanoparticles. - Int. J. Pharm., 101, 165-168, 1994.
-
(1994)
Int. J. Pharm.
, vol.101
, pp. 165-168
-
-
Scherer, D.1
Robinson, J.R.2
Kreuter, J.3
-
55
-
-
75149147526
-
Biodegradation, biodistribution and toxicity of chitosan
-
Kean T., Thanou M. - Biodegradation, biodistribution and toxicity of chitosan. - Adv. Drug Deliv. Rev., 62, 3-11, 2010.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 3-11
-
-
Kean, T.1
Thanou, M.2
-
56
-
-
0032472388
-
Tumor accumulation of poly(vinyl alcohol) of different sizes after intravenous injection
-
Tabata Y., Murakami Y., Ikada Y. - Tumor accumulation of poly(vinyl alcohol) of different sizes after intravenous injection. - J. Control. Release, 50, 123-133, 1998.
-
(1998)
J. Control. Release
, vol.50
, pp. 123-133
-
-
Tabata, Y.1
Murakami, Y.2
Ikada, Y.3
-
57
-
-
0034601237
-
Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-coglycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres
-
Jung T., Breitenbach A., Kissel T. - Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-coglycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres. - J. Control. Rel., 67, 157-169, 2000.
-
(2000)
J. Control. Rel.
, vol.67
, pp. 157-169
-
-
Jung, T.1
Breitenbach, A.2
Kissel, T.3
-
58
-
-
62649139973
-
ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells
-
Chittasupho C., Xie S., Baoum A., Yakovleva T., Siahaan T., Berkland C. - ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells. - Eur. J. Pharm. Sci., 37, 141-150, 2009.
-
(2009)
Eur. J. Pharm. Sci.
, vol.37
, pp. 141-150
-
-
Chittasupho, C.1
Xie, S.2
Baoum, A.3
Yakovleva, T.4
Siahaan, T.5
Berkland, C.6
-
59
-
-
67349255031
-
The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalation
-
Tseng C., Su W., Yen K., Yang K., Lin F. - The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalation. - Biomaterials, 30, 3476-3485, 2009.
-
(2009)
Biomaterials
, vol.30
, pp. 3476-3485
-
-
Tseng, C.1
Su, W.2
Yen, K.3
Yang, K.4
Lin, F.5
-
60
-
-
67349106708
-
Preparation and properties of inhalable nanocomposite particles for treatment of lung cancer
-
Tomoda K., Ohkoshi T., Hirota K., Sonavane G., Nakajima T., Terada H., Komuro M., Kitazato K., Makino K. - Preparation and properties of inhalable nanocomposite particles for treatment of lung cancer. - Colloid Surf. B-Biointerfaces, 71, 177-182, 2009.
-
(2009)
Colloid Surf. B-Biointerfaces
, vol.71
, pp. 177-182
-
-
Tomoda, K.1
Ohkoshi, T.2
Hirota, K.3
Sonavane, G.4
Nakajima, T.5
Terada, H.6
Komuro, M.7
Kitazato, K.8
Makino, K.9
-
61
-
-
67650093219
-
Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery
-
Sung J., Padilla D., Garcia-Contreras L., VerBerkmoes J., Durbin D., Peloquin C., Elbert K., Hickey A., Edwards D. - Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery. - Pharm. Res., 26, 1847-1855, 2009.
-
(2009)
Pharm. Res.
, vol.26
, pp. 1847-1855
-
-
Sung, J.1
Padilla, D.2
Garcia-Contreras, L.3
VerBerkmoes, J.4
Durbin, D.5
Peloquin, C.6
Elbert, K.7
Hickey, A.8
Edwards, D.9
-
62
-
-
61649118970
-
One-step preparation of rifampicin/poly (lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis
-
Ohashi K., Kabasawa T., Ozeki T., Okada H. - One-step preparation of rifampicin/poly (lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis. - J. Control. Rel., 135, 19-24, 2009.
-
(2009)
J. Control. Rel.
, vol.135
, pp. 19-24
-
-
Ohashi, K.1
Kabasawa, T.2
Ozeki, T.3
Okada, H.4
-
63
-
-
0036001389
-
Transfer of lipophilic markers from PLGA and polystyrene nanoparticles to Caco-2 monolayers mimics particle uptake
-
Pietzonka P., Rothen-Rutishauser B., Langguth P., Wunderli-Allenspach H., Walter E., Merkle H. - Transfer of lipophilic markers from PLGA and polystyrene nanoparticles to Caco-2 monolayers mimics particle uptake. - Pharm. Res., 19, 595-601, 2002.
-
(2002)
Pharm. Res.
, vol.19
, pp. 595-601
-
-
Pietzonka, P.1
Rothen-Rutishauser, B.2
Langguth, P.3
Wunderli-Allenspach, H.4
Walter, E.5
Merkle, H.6
-
64
-
-
33847261116
-
Effervescent dry powder for respiratory drug delivery
-
Ely L., Roa W., Finlay W., Löbenberg R. - Effervescent dry powder for respiratory drug delivery. - Eur. J. Pharm. Biopharm., 65, 346-353, 2007.
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.65
, pp. 346-353
-
-
Ely, L.1
Roa, W.2
Finlay, W.3
Löbenberg, R.4
-
65
-
-
52149095437
-
Formulation and in vivo evaluation of effervescent inhalable carrier particles for pulmonary delivery of nanoparticles
-
Azarmi S., Löbenberg R., Roa W., Tai S., Finlay W. - Formulation and in vivo evaluation of effervescent inhalable carrier particles for pulmonary delivery of nanoparticles. - Drug Dev. Ind. Pharm., 34, 943-947, 2008.
-
(2008)
Drug Dev. Ind. Pharm.
, vol.34
, pp. 943-947
-
-
Azarmi, S.1
Löbenberg, R.2
Roa, W.3
Tai, S.4
Finlay, W.5
-
66
-
-
60549086379
-
In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application
-
Beyerle A., Höbel S., Czubayko F., Schulz H., Kissel T., Aigner A., Stoeger T. - In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application. - Toxicol. Vitro, 23, 500-508, 2009.
-
(2009)
Toxicol. Vitro
, vol.23
, pp. 500-508
-
-
Beyerle, A.1
Höbel, S.2
Czubayko, F.3
Schulz, H.4
Kissel, T.5
Aigner, A.6
Stoeger, T.7
-
67
-
-
52449086630
-
Cospray dried antibiotics for dry powder lung delivery
-
Adi H., Young P., Chan H., Stewart P., Agus H., Traini D. - Cospray dried antibiotics for dry powder lung delivery. - J. Pharm. Sci., 97, 3356-3366, 2008.
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 3356-3366
-
-
Adi, H.1
Young, P.2
Chan, H.3
Stewart, P.4
Agus, H.5
Traini, D.6
-
68
-
-
43249086246
-
Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation. 1. Influence of polymer concentration on physical and in vitro characteristics
-
Salama R., Hoe S., Chan H., Traini D., Young P. - Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation. 1. Influence of polymer concentration on physical and in vitro characteristics - Eur. J. Pharm. Biopharm., 69, 486-495, 2008.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.69
, pp. 486-495
-
-
Salama, R.1
Hoe, S.2
Chan, H.3
Traini, D.4
Young, P.5
-
69
-
-
50149083441
-
Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation. 2. Evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols
-
Salama R.O., Traini D., Chan H.-K., Young P.M. - Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation. 2. Evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols. - Eur. J. Pharm. Biopharm., 70, 145-152, 2008.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, pp. 145-152
-
-
Salama, R.O.1
Traini, D.2
Chan, H.-K.3
Young, P.M.4
-
70
-
-
70350608232
-
A poly (vinyl alcohol) nanoparticle platform for kinetic studies of inhaled particles
-
Gul M., Jones S., Dailey L., Nacer H., Ma Y., Sadouki F., Hider R., Araman A., Forbes B. - A poly (vinyl alcohol) nanoparticle platform for kinetic studies of inhaled particles. - Inhal. Toxicol., 21, 631-640, 2009.
-
(2009)
Inhal. Toxicol.
, vol.21
, pp. 631-640
-
-
Gul, M.1
Jones, S.2
Dailey, L.3
Nacer, H.4
Ma, Y.5
Sadouki, F.6
Hider, R.7
Araman, A.8
Forbes, B.9
-
71
-
-
67349179948
-
Poly (vinyl alcohol) nanoparticle stability in biological media and uptake in respiratory epithelial cell layers in vitro
-
Madlova M., Jones S., Zwerschke I., Ma Y., Hider R., Forbes B. - Poly (vinyl alcohol) nanoparticle stability in biological media and uptake in respiratory epithelial cell layers in vitro. - Eur. J. Pharm. Biopharm., 72, 438-443, 2009.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.72
, pp. 438-443
-
-
Madlova, M.1
Jones, S.2
Zwerschke, I.3
Ma, Y.4
Hider, R.5
Forbes, B.6
-
72
-
-
0032863681
-
Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect
-
Kawashima Y., Yamamoto H., Takeuchi H., Fujioka S., Hino T. - Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect. - J. Control. Release, 62, 279-287, 1999.
-
(1999)
J. Control. Release
, vol.62
, pp. 279-287
-
-
Kawashima, Y.1
Yamamoto, H.2
Takeuchi, H.3
Fujioka, S.4
Hino, T.5
-
73
-
-
20744434748
-
Microencapsulated chitosan nanoparticles for lung protein delivery
-
Grenha A., Seijo B., Remuñán-López C. - Microencapsulated chitosan nanoparticles for lung protein delivery. - Eur. J. Pharm. Sci., 25, 427-437, 2005.
-
(2005)
Eur. J. Pharm. Sci.
, vol.25
, pp. 427-437
-
-
Grenha, A.1
Seijo, B.2
Remuñán-López, C.3
-
74
-
-
37849051886
-
Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery
-
Amidi M., Pellikaan H., de Boer A., Crommelin D., Hennink W., Jiskoot W. - Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery. - Eur. J. Pharm. Biopharm., 68, 191-200, 2008.
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.68
, pp. 191-200
-
-
Amidi, M.1
Pellikaan, H.2
De Boer, A.3
Crommelin, D.4
Hennink, W.5
Jiskoot, W.6
-
75
-
-
11844282711
-
Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions
-
Yamamoto H., Kuno Y., Sugimoto S., Takeuchi H., Kawashima Y. - Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions. - J. Control. Release, 102, 373-381, 2005.
-
(2005)
J. Control. Release
, vol.102
, pp. 373-381
-
-
Yamamoto, H.1
Kuno, Y.2
Sugimoto, S.3
Takeuchi, H.4
Kawashima, Y.5
-
76
-
-
0035821406
-
Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats
-
Zhang Q., Shen Z., Nagai T. - Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats. - Int. J. Pharm., 218, 75-80, 2001.
-
(2001)
Int. J. Pharm.
, vol.218
, pp. 75-80
-
-
Zhang, Q.1
Shen, Z.2
Nagai, T.3
-
77
-
-
20444377785
-
Polyethylenimine-based non-viral gene delivery systems
-
Lungwitz U., Breunig M., Blunk T., Göpferich A. - Polyethylenimine-based non-viral gene delivery systems. - Eur. J. Pharm. Biopharm., 60, 247-266, 2005.
-
(2005)
Eur. J. Pharm. Biopharm.
, vol.60
, pp. 247-266
-
-
Lungwitz, U.1
Breunig, M.2
Blunk, T.3
Göpferich, A.4
-
78
-
-
34250881578
-
Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library
-
Thomas M., Lu J., Zhang C., Chen J., Klibanov A. - Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library. - Pharm. Res., 24, 1564-1571, 2007.
-
(2007)
Pharm. Res.
, vol.24
, pp. 1564-1571
-
-
Thomas, M.1
Lu, J.2
Zhang, C.3
Chen, J.4
Klibanov, A.5
-
79
-
-
40949100345
-
Poly (β-amino ester) as a carrier for si/shRNA delivery in lung cancer cells
-
Jere D., Xu C., Arote R., Yun C., Cho M., Cho C. - Poly (β-amino ester) as a carrier for si/shRNA delivery in lung cancer cells. - Biomaterials, 29, 2535-2547, 2008.
-
(2008)
Biomaterials
, vol.29
, pp. 2535-2547
-
-
Jere, D.1
Xu, C.2
Arote, R.3
Yun, C.4
Cho, M.5
Cho, C.6
-
80
-
-
33750465842
-
A biodegradable poly (ester amine) based on polycaprolactone and polyethylenimine as a gene carrier
-
Arote R., Kim T., Kim Y., Hwang S., Jiang H., Song H., Nah J., Cho M., Cho C. - A biodegradable poly (ester amine) based on polycaprolactone and polyethylenimine as a gene carrier. - Biomaterials, 28, 735-744, 2007.
-
(2007)
Biomaterials
, vol.28
, pp. 735-744
-
-
Arote, R.1
Kim, T.2
Kim, Y.3
Hwang, S.4
Jiang, H.5
Song, H.6
Nah, J.7
Cho, M.8
Cho, C.9
-
81
-
-
37349101929
-
Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol- graft-trimethyl chitosan block copolymers: Establishment of structure-activity relationships in vitro
-
Germershaus O., Mao S., Sitterberg J., Bakowsky U., Kissel T. - Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. - J. Control. Rel., 125, 145-154, 2008.
-
(2008)
J. Control. Rel.
, vol.125
, pp. 145-154
-
-
Germershaus, O.1
Mao, S.2
Sitterberg, J.3
Bakowsky, U.4
Kissel, T.5
-
82
-
-
0032484162
-
Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery
-
MacLaughlin F., Mumper R., Wang J., Tagliaferri J., Gill I., Hinchcliffe M., Rolland A. - Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. - J. Control. Rel., 56, 259-272, 1998.
-
(1998)
J. Control. Rel.
, vol.56
, pp. 259-272
-
-
MacLaughlin, F.1
Mumper, R.2
Wang, J.3
Tagliaferri, J.4
Gill, I.5
Hinchcliffe, M.6
Rolland, A.7
-
83
-
-
0034786764
-
Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
-
Köping-Höggård M., Tubulekas I., Guan H., Edwards K., Nilsson M., Vårum K., Artursson P. - Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. - Gene Ther., 8, 1108-1121, 2001.
-
(2001)
Gene Ther.
, vol.8
, pp. 1108-1121
-
-
Köping-Höggård, M.1
Tubulekas, I.2
Guan, H.3
Edwards, K.4
Nilsson, M.5
Vårum, K.6
Artursson, P.7
-
84
-
-
5444267326
-
Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers
-
Köping-Höggård M., Vårum K., Issa M., Danielsen S., Christensen B., Stokke B., Artursson P. - Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers. - Gene Ther., 11, 1441-1452, 2004.
-
(2004)
Gene Ther.
, vol.11
, pp. 1441-1452
-
-
Köping-Höggård, M.1
Vårum, K.2
Issa, M.3
Danielsen, S.4
Christensen, B.5
Stokke, B.6
Artursson, P.7
-
85
-
-
33748054817
-
RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
-
Howard K., Rahbek U., Liu X., Damgaard C., Glud S., Andersen M., Hovgaard M., Schmitz A., Nyengaard J., Besenbacher F. - RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. - Mol. Ther., 14, 476-484, 2006.
-
(2006)
Mol. Ther.
, vol.14
, pp. 476-484
-
-
Howard, K.1
Rahbek, U.2
Liu, X.3
Damgaard, C.4
Glud, S.5
Andersen, M.6
Hovgaard, M.7
Schmitz, A.8
Nyengaard, J.9
Besenbacher, F.10
-
86
-
-
33751419974
-
The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing
-
DOI 10.1016/j.biomaterials.2006.11.004, PII S0142961206009501
-
Liu X., Howard K., Dong M., Andersen M., Rahbek U., Johnsen M., Hansen O., Besenbacher F., Kjems J. - The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. - Biomaterials, 28, 1280-1288, 2007. (Pubitemid 44816373)
-
(2007)
Biomaterials
, vol.28
, Issue.6
, pp. 1280-1288
-
-
Liu, X.1
Howard, K.A.2
Dong, M.3
Andersen, M.O.4
Rahbek, U.L.5
Johnsen, M.G.6
Hansen, O.C.7
Besenbacher, F.8
Kjems, J.9
-
87
-
-
67650608146
-
Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells
-
Jere D., Jiang H., Kim Y., Arote R., Choi Y., Yun C., Cho M., Cho C. - Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells. - Int. J. Pharm., 378, 194-200, 2009.
-
(2009)
Int. J. Pharm.
, vol.378
, pp. 194-200
-
-
Jere, D.1
Jiang, H.2
Kim, Y.3
Arote, R.4
Choi, Y.5
Yun, C.6
Cho, M.7
Cho, C.8
-
88
-
-
61349092292
-
Studies on bioadhesive PLGA nanoparticles: A promising gene delivery system for efficient gene therapy to lung cancer
-
Zou W., Liu C., Chen Z., Zhang N. - Studies on bioadhesive PLGA nanoparticles: a promising gene delivery system for efficient gene therapy to lung cancer - Int. J. Pharm., 370, 187-195, 2009.
-
(2009)
Int. J. Pharm.
, vol.370
, pp. 187-195
-
-
Zou, W.1
Liu, C.2
Chen, Z.3
Zhang, N.4
-
89
-
-
77649186723
-
Chitosan-modified poly(d,l-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects
-
Tahara K., Yamamoto H., Hirashima N., Kawashima Y. - Chitosan-modified poly(d,l-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects. - Eur. J. Pharm. Biopharm., 74, 421-426, 2010.
-
(2010)
Eur. J. Pharm. Biopharm.
, vol.74
, pp. 421-426
-
-
Tahara, K.1
Yamamoto, H.2
Hirashima, N.3
Kawashima, Y.4
-
90
-
-
34548244065
-
Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: Effect of the formulation parameters on complexation and transfection of antisense oligonucleotides
-
Nafee N., Taetz S., Schneider M., Schaefer U., Lehr C. - Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides. - Nanomedicine, 3, 173-183, 2007.
-
(2007)
Nanomedicine
, vol.3
, pp. 173-183
-
-
Nafee, N.1
Taetz, S.2
Schneider, M.3
Schaefer, U.4
Lehr, C.5
-
91
-
-
77951276022
-
Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells
-
Baoum A., Dhillon N., Buch S., Berkland C. - Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells. - J. Pharm. Sci., 99, 2413-2422, 2010.
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 2413-2422
-
-
Baoum, A.1
Dhillon, N.2
Buch, S.3
Berkland, C.4
-
92
-
-
56849117151
-
Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy
-
Nguyen J., Steele T., Merkel O., Reul R., Kissel T. - Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy. - J. Control. Release, 132, 243-251, 2008.
-
(2008)
J. Control. Release
, vol.132
, pp. 243-251
-
-
Nguyen, J.1
Steele, T.2
Merkel, O.3
Reul, R.4
Kissel, T.5
-
93
-
-
70349826234
-
Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells
-
Nguyen J., Reul R., Betz T., Dayyoub E., Schmehl T., Gessler T., Bakowsky U., Seeger W., Kissel T. - Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells. - J. Control. Rel., 140, 47-54, 2009.
-
(2009)
J. Control. Rel.
, vol.140
, pp. 47-54
-
-
Nguyen, J.1
Reul, R.2
Betz, T.3
Dayyoub, E.4
Schmehl, T.5
Gessler, T.6
Bakowsky, U.7
Seeger, W.8
Kissel, T.9
-
94
-
-
68549083357
-
Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems
-
Reul R., Nguyen J., Kissel T. - Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems. - Biomaterials, 30, 5815-5824, 2009.
-
(2009)
Biomaterials
, vol.30
, pp. 5815-5824
-
-
Reul, R.1
Nguyen, J.2
Kissel, T.3
-
95
-
-
34748868940
-
Computational analyses of a pressurized metered dose inhaler and a new drug-aerosol targeting methodology
-
Kleinstreuer C., Shi H., Zhang Z. - Computational analyses of a pressurized metered dose inhaler and a new drug-aerosol targeting methodology. - J. Aerosol Med. Pulm. Drug Deliv., 20, 294-309, 2007.
-
(2007)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.20
, pp. 294-309
-
-
Kleinstreuer, C.1
Shi, H.2
Zhang, Z.3
-
96
-
-
67650679365
-
Non-viral vectors in cystic fibrosis gene therapy: Recent developments and future prospects
-
Pringle I., Hyde S., Gill D. - Non-viral vectors in cystic fibrosis gene therapy: recent developments and future prospects. - Expert Opin. Biol. Ther., 9, 991-1003, 2009.
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, pp. 991-1003
-
-
Pringle, I.1
Hyde, S.2
Gill, D.3
-
97
-
-
51049084639
-
Inhalable siRNA: Potential as a therapeutic agent in the lungs
-
Durcan N., Murphy C., Cryan S. - Inhalable siRNA: potential as a therapeutic agent in the lungs. - Mol. Pharm., 5, 559-566, 2008.
-
(2008)
Mol. Pharm.
, vol.5
, pp. 559-566
-
-
Durcan, N.1
Murphy, C.2
Cryan, S.3
-
98
-
-
41449090371
-
Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme
-
Sci S., Wegmann M., Dicke T., Henke W., Yildirim A., Renz H., Garn H. - Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme. - Journal of Allergy and Clinical Immunology, 121, 910-916, 2008.
-
(2008)
Journal of Allergy and Clinical Immunology
, vol.121
, pp. 910-916
-
-
Sci, S.1
Wegmann, M.2
Dicke, T.3
Henke, W.4
Yildirim, A.5
Renz, H.6
Garn, H.7
-
99
-
-
33947585368
-
Current drug targets and future therapy of pulmonary arterial hypertension
-
Ito T., Ozawa K., Shimada K. - Current drug targets and future therapy of pulmonary arterial hypertension. - Curr. Med. Chem., 14, 719-733, 2007.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 719-733
-
-
Ito, T.1
Ozawa, K.2
Shimada, K.3
-
100
-
-
73949141209
-
Biodegradable polyelectrolyte microcapsules: Antigen delivery tools with Th17 skewing activity after pulmonary delivery
-
De Koker S., Naessens T., De Geest B.G., Bogaert P., Demeester J., De Smedt S., Grooten J. - Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery. - J. Immunol., 184, 203-211.
-
J. Immunol.
, vol.184
, pp. 203-211
-
-
De Koker, S.1
Naessens, T.2
De Geest, B.G.3
Bogaert, P.4
Demeester, J.5
De Smedt, S.6
Grooten, J.7
-
101
-
-
85007764407
-
Why is Exubera being withdrawn?
-
Bailey C., Barnett A. - Why is Exubera being withdrawn? - Br. Med. J., 335, 1156, 2007.
-
(2007)
Br. Med. J.
, vol.335
, pp. 1156
-
-
Bailey, C.1
Barnett, A.2
-
102
-
-
75549083827
-
EGFR signaling and drug discovery
-
Lurje G., Lenz H. - EGFR signaling and drug discovery. - Oncology, 77, 400-410, 2009.
-
(2009)
Oncology
, vol.77
, pp. 400-410
-
-
Lurje, G.1
Lenz, H.2
|