Synthesis of linear polyamines with different amine spacings and their ability to form dsDNA/siRNA complexes suitable for transfection

Macromolecular Bioscience

Volumn 10, Issue 9, 2010, Pages 1073-1083

  Fischer, Wiebke ^a   Brissault, Blandine ^a   Prévost, Sylvain ^c,d   Kopaczynska, Marta ^a   Andreou, Ioanna ^b   Janosch, Andrea ^b   Gradzielski, Michael ^c   Haag, Rainer ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b QIAGEN GMBH   (Germany)

^c TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^d HAHN MEITNER INSTITUT   (Germany)

Author keywords

Atomic force microscopy (AFM); Cytotoxicity; DNA polyplex; Gene transfection; Linear polyamines

Indexed keywords

AFM IMAGE; DNA COMPLEX; GENE TRANSFECTION; PHOSPHATE GROUP; POLY(PROPYLENE IMINE); POLYAMINES; POLYETHYLENEIMINE; POLYPLEXES; SMALL-ANGLE NEUTRON SCATTERING; SPHERICAL AGGREGATES; TRANSFECTION EFFICIENCY;

AMINES; ATOMIC FORCE MICROSCOPY; ATOMS; BUTENES; DNA; ETHYLENE; GENES; NEUTRON SCATTERING; NUCLEIC ACIDS; PHOSPHORUS; PROPYLENE;

COMPLEXATION;

DOUBLE STRANDED DNA; NITROGEN; PHOSPHATE; PHOSPHORUS; POLYAMINE; SMALL INTERFERING RNA;

ANALYTIC METHOD; ARTICLE; ATOMIC FORCE MICROSCOPY; COMPLEX FORMATION; CYTOTOXICITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NEUTRON SCATTERING; SYNTHESIS;

DNA; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ATOMIC FORCE; NANOPARTICLES; NEUTRON DIFFRACTION; POLYAMINES; RNA, SMALL INTERFERING; SCATTERING, SMALL ANGLE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 77956629693     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201000082     Document Type: Article

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