Polymers for gene delivery: Charged for success

Nature Materials

Volumn 11, Issue 1, 2012, Pages 10-12

  Mastrobattista, Enrico ^a   Hennink, Wim E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHARGE DENSITY; DNA; ESTERS; GENE TRANSFER; GENES; HYDROPHOBICITY; MOLECULAR BIOLOGY; MOLECULAR WEIGHT;

CATIONIC POLYMERS; HIGH MOLECULAR WEIGHT; HIGHER EFFICIENCY; HYDROPHOBIC GROUPS; POSITIVE SURFACE CHARGE; SYNTHESIZED POLYMERS; TRANSFECTION ACTIVITY; TRANSFECTION AGENTS;

BIODEGRADABLE POLYMERS;

POLYAMINE; POLYMER;

ANIMAL; CHEMISTRY; FEMALE; GENE TRANSFER; HUMAN; NOTE;

ANIMALS; FEMALE; GENE TRANSFER TECHNIQUES; HUMANS; POLYAMINES; POLYMERS;

EID: 83655211651     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat3209     Document Type: Short Survey

References (7)

1. Edelstein, M. L. et al. J. Gene Med. 9, 833-842 (2007).
2. Li, S. D. et al. J. Control. Release 123, 181-183 (2007).
3. Mastrobattista, E. et al. Nature Rev. Drug Discov. 5, 115-121 (2006).
4. Mintzer M. A. et al. Chem. Rev. 109, 259-302 (2009).
5. Zhou, J. et al. Nature Mater. 11, 82-90 (2012).
6. Kurisawa, M., Yokoyama, M. & Okano, T. J. Control. Release 68, 1-8 (2000).
7. Van Gaal E. V. B. et al. J. Control. Release 154, 218-232 (2011).