Polymerized spermine as a novel polycationic nucleic acid carrier system

International Journal of Pharmaceutics

Volumn 434, Issue 1-2, 2012, Pages 437-443

  Du, Zixiu ^a   Chen, Moying ^a   He, Qianqian ^a   Zhou, Yi ^a   Jin, Tuo ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Cytotoxicity; Gene delivery; Gene silencing; Polyspermine; Transfection

Indexed keywords

BUFFER; DNA; LUCIFERASE; NANOPARTICLE; NUCLEIC ACID; POLYCATION; POLYMER; POLYSPERMINE AMIDE; POLYSPERMINE CARBAMATE; POLYSPERMINE IMINE; SMALL INTERFERING RNA; SPERMINE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CELL STRAIN COS7; CELL STRAIN HEPG2; CELL VIABILITY; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG DEGRADATION; DRUG HALF LIFE; GENE SILENCING; GENETIC LINKAGE; GENETIC TRANSFECTION; HYDROLYSIS; INCUBATION TEMPERATURE; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; NUCLEIC ACID TRANSPORT; PARTICLE SIZE; PLASMID; POLYMERIZATION; PRIORITY JOURNAL; ZETA POTENTIAL;

AMIDES; ANIMALS; CARBAMATES; CATIONS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; COS CELLS; DNA; GENE SILENCING; GENE TRANSFER TECHNIQUES; HALF-LIFE; HEP G2 CELLS; HUMANS; IMINES; NANOPARTICLES; PARTICLE SIZE; PLASMIDS; POLYMERS; RNA, SMALL INTERFERING; SPERMINE; TRANSFECTION;

EID: 84864136506     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.05.065     Document Type: Article

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