Chitosan-graft-spermine as a gene carrier in vitro and in vivo

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 1, 2011, Pages 36-42

  Jiang, Hu Lin ^a   Lim, Hwang Tae ^a   Kim, You Kyoung ^a   Arote, Rohidas ^a   Shin, Ji Young ^a   Kwon, Jung Taek ^a   Kim, Ji Eun ^a   Kim, Ji Hye ^a   Kim, Duyeol ^a   Chae, Chanhee ^a   Nah, Jae Woon ^b   Choi, Yun Jaie ^a   Cho, Chong Su ^a   Cho, Myung Haing ^a  

^a Seoul National University   (South Korea)

^b Sunchon National University   (South Korea)

Author keywords

Aerosol delivery; Chitosan; Cytotoxicity; Gene therapy; Non viral gene delivery; Spermine

Indexed keywords

CHITOSAN; CHITOSAN GRAFT SPERMINE; COPOLYMER; PLASMID DNA; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DNA BINDING; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; NONVIRAL GENE DELIVERY SYSTEM;

ADMINISTRATION, INHALATION; ANIMALS; CELL LINE; CELL SURVIVAL; CHITOSAN; GENE THERAPY; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HUMANS; LUNG; MALE; MICE; MICE, INBRED C57BL; NANOPARTICLES; PHYSICOCHEMICAL PHENOMENA; PLASMIDS; POLYMERS; RANDOM ALLOCATION; SPERMINE; TOXICITY TESTS;

EID: 78650695293     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.09.014     Document Type: Article

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