Radiosyntheses using fluorine-18: The art and science of late stage fluorination

Current Topics in Medicinal Chemistry

Volumn 14, Issue 7, 2014, Pages 875-900

  Cole, Erin L ^a   Stewart, Megan N ^b   Littich, Ryan ^a   Hoareau, Raphael ^a   Scott, Peter J H ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Fluorine 18; PET imaging; Positron emission tomography; Radiochemistry; Radiopharmaceutical synthesis

Indexed keywords

2 FLUORO L TYROSINE F18; 3 (2 AZETIDINYLMETHOXY)PYRIDINE; 4 FLUORO M TYROSINE F18; 6 FLUORODOPAMINE F18; 6 FLUOROMETARAMINOL F18; CARBON 11; DIAZEPAM; DIETHYLAMINOSULFUR TRIFLUORIDE F18; FLUOROANTIPYRINE F18; FLUORODEOXYGLUCOSE F 18; FLUOROTYROSINE F18; FLUOROURACIL F18; GERMANIUM; GLUCOSE TRANSPORTER; L 3,4 DIHYDROXY 6 FLUOROPHENYLALANINE F18; LEVODOPA; METARAMINOL; N FLUORO N ALKYLSULFONAMIDE F 18; N FLUORO PYRIDONE F18; N FLUOROBENZENESULFONAMIDE F18; N FLUOROPYRIDINIUM TRIFLATE F 18; N FLUOROPYRIDONE F18; NITROGEN 13; NITROSYL FLUORIDE F18; OXYGEN 15; OXYGEN 18; PERCHLORYL FLUORIDE F 18; RADIOPHARMACEUTICAL AGENT; SELECTFLUOR BIS(TRIFLATE) F18; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENON DIFLUORIDE F18;

ALZHEIMER DISEASE; ARTICLE; BLOOD BRAIN BARRIER; DRUG SYNTHESIS; ELECTROPHILIC FLUORINATION; ELECTROPHILICITY; FLUORINATION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; NUCLEOPHILIC ALIPHATIC FLUORINATION; NUCLEOPHILICITY; PARKINSON DISEASE; PHOTOCHEMISTRY; POSITRON EMISSION TOMOGRAPHY; RADIOSYNTHESIS;

ANIMALS; DRUG DESIGN; FLUORINE RADIOISOTOPES; HALOGENATION; HUMANS; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RADIOPHARMACEUTICALS;

EID: 84897448248     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666140202205035     Document Type: Article

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