One-step high-radiochemical-yield synthesis of [18F]FP-CIT using a protic solvent system

Nuclear Medicine and Biology

Volumn 34, Issue 4, 2007, Pages 345-351

  Lee, Sang Ju ^a,b   Oh, Seung Jun ^a   Chi, Dae Yoon ^b   Kang, Se Hun ^a   Kil, Hee Seup ^b   Kim, Jae Seung ^a   Moon, Dae Hyuk ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Inha University   (South Korea)

Author keywords

18F FP CIT; Dopamine transporter; Nucleophilic substitution; Parkinson's disease; Protic solvent

Indexed keywords

FLUOROPROPYLCARBOMETHOXYIODOPHENYLNORTROPANE F 18; RADIOPHARMACEUTICAL AGENT; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG PURIFICATION; DRUG SYNTHESIS; ELUTION; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RADIOCHEMISTRY; REPRODUCIBILITY;

AUTOMATION; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; FLUORINE RADIOISOTOPES; INDICATORS AND REAGENTS; ISOTOPE LABELING; QUALITY CONTROL; RADIOPHARMACEUTICALS; SOLVENTS; TROPANES;

EID: 34248185541     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2007.02.007     Document Type: Article

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