[18F]-EF5, a marker for PET detection of hypoxia: Synthesis of precursor and a new fluorination procedure

Applied Radiation and Isotopes

Volumn 54, Issue 1, 2001, Pages 73-80

  Dolbier Jr , William R ^a   Li, An Rong ^a   Koch, Cameron J ^b   Shiue, Chyng Yann ^b   Kachur, Alexander V ^b  

^a University of Florida ^*  (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE; 2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE F 18; FLUORINE 18; UNCLASSIFIED DRUG; 2-(2-NITRO-1H-IMIDAZOL-1-YL)-N-(2,2,3,3,3-PENTAFLUOROPROPYL)ACETAMIDE; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; ETANIDAZOLE; FLUORINATED HYDROCARBON; FLUORINE; RADIOPHARMACEUTICAL AGENT;

ARTICLE; FLUORINATION; HYPOXIA; ISOTOPE LABELING; METABOLISM; NONHUMAN; OXYGEN TENSION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; SYNTHESIS; URINARY EXCRETION; ANIMAL; ANOXIA; CHEMISTRY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; SCINTISCANNING;

ANIMALS; ANOXIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETANIDAZOLE; FLUORINE RADIOISOTOPES; HUMANS; HYDROCARBONS, FLUORINATED; INDICATORS AND REAGENTS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

ACETIC ACID; CHEMICAL BONDS; FLUORINE; FLUORINE CONTAINING POLYMERS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIVING SYSTEMS STUDIES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN; POSITRON EMISSION TOMOGRAPHY; SYNTHESIS (CHEMICAL); TISSUE;

BIODISTRIBUTION; ELECTROPHILIC FLUORINATION; FLUORINATED ALKENE BOND; TISSUE HYPOXIA; TRIFLUOROACETIC ACID;

RADIOACTIVE TRACERS;

EID: 0035503276     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8043(00)00102-0     Document Type: Article

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