Implementation and validation of an adaptive template registration method for 18F-flutemetamol imaging data

Journal of Nuclear Medicine

Volumn 54, Issue 8, 2013, Pages 1472-1478

  Lundqvist, Roger ^a   Lilja, Johan ^a   Thomas, Benjamin A ^b   Lötjönen, Jyrki ^c   Villemagne, Victor L ^d   Rowe, Christopher C ^d   Thurfjell, Lennart ^a  

^a BIACORE AB   (Sweden)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^d AUSTIN HEALTH   (Australia)

Author keywords

18F flutemetamol; Amyloid imaging; Image registration

Indexed keywords

AMYLOID BETA PROTEIN; CARBON 11; FLUTEMETAMOL F 18;

AMYLOID PLAQUE; ARTICLE; BRAIN MAPPING; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; DRUG UPTAKE; GRAY MATTER; HUMAN; IMAGE ANALYSIS; NEOCORTEX; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STRIATE CORTEX; VASCULAR AMYLOIDOSIS; WHITE MATTER;

18F-FLUTEMETAMOL; AMYLOID IMAGING; IMAGE REGISTRATION;

ADULT; ALZHEIMER DISEASE; ANILINE COMPOUNDS; BENZOTHIAZOLES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; STATISTICS AS TOPIC;

EID: 84881461022     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.112.115006     Document Type: Article

References (28)

1. Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol. 2004;55:306-319.
2. Wong DF, Rosenberg PB, Zhou Y, et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir F 18). J Nucl Med. 2010;51:913-920.
3. Clark CM, Schneider JA, Bedell BJ, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA. 2011;305:275-283.
4. Nelissen N, Van Laere K, Thurfjell L, et al. Phase I study of the PIB derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer's disease. J Nucl Med. 2009;50:1251-1259.
5. Vandenberghe R, Van Laere K, Ivanoiu A, et al. 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial. Ann Neurol. 2010;68:319-329.
6. Barthel H, Gertz HJ, Dresel S, et al. Cerebral amyloid-beta PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study. Lancet Neurol. 2011;10:424-435.
7. Villemagne VL, Ong K, Mulligan RS, et al. Amyloid imaging with 18F-florbetaben in Alzheimer disease and other dementias. J Nucl Med. 2011;52:1210-1217.
8. Lopresti BJ, Klunk WE, Mathis CA, et al. Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med. 2005;46:1959-1972.
9. Klunk WE, Price JC, Chester AM, et al. Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci. 2007;27:6174-6184.
10. 11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain. 2008;131:1845-1853.
11. Rowe CC, Ng S, Ackermann U, et al. Imaging b-amyloid burden in aging and dementia. Neurology. 2007;68:1718-1725.
12. Barthel H, Luthardt J, Becker G, et al. Individualized quantification of brain b-amyloid burden: results of a proof of mechanism phase 0 florbetaben PET trial in patients with Alzheimer's disease and healthy controls. Eur J Nucl Med Mol Imaging. 2011;38:1702-1714.
13. Ashburner J, Friston KJ. Spatial transformation of images. In: Frackowiak RSJ, Friston KJ, Frith C, Dolan R, Mazziotta JC, eds. Human Brain Function. London, U.K.: Academic Press, 1997:43-58.
14. 11C-PiB PET assessment of change in fibrillar amyloid-b load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. Lancet Neurol. 2010;9:363-372.
15. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MR imaging single-subject brain. Neuroimage. 2002;15:273-289.
16. 11C PiB and structural MR imaging provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain. 2008;131:665-680.
17. Fischl B, Salat DH, Busa E, et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron. 2002;33:341-355.
18. Thomas BA, Erlandsson K, Modat M, et al. The importance of appropriate partial volume correction for PET quantification in Alzheimer's disease. Eur J Nucl Med Mol Imaging. 2011;38:1104-1119.
19. Minoshima S, Frey KA, Koeppe RA, Foster NL, Kuhl DE. A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET. J Nucl Med. 1995;36:1238-1248.
20. Herholz K, Salmon E, Perani D, et al. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage. 2002;17:302-316.
21. Maes F, Collignon A, Vandermeulen D, Marchal G, Suetens P. Multimodality image registration by maximization of mutual information. IEEE Trans Med Imaging. 1997;16:187-198.
22. Rowe CC, Ellis KA, Rimajova M, et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging. 2010;31:1275-1283.
23. Evans AC, Collins DL, Millst SR, Brown ED, Kelly RL, Peters TM. 3D statistical neuroanatomical models from 305 MR imaging volumes. IEEE Nucl Sci Symp Conf Rec. 1993:1813-1817.
24. ICBM-152 template. Available at: http://packages.bic.mni.mcgill.ca/tgz/ mni-models- icbm152-lin-1.0.tar.gz. Accessed June 4, 2013.
25. Powell MJD. An efficient method of finding the minimum of a function of several variables without calculating derivatives. Comput J. 1964;7:155-162.
26. Thurfjell L, Bohm C, Greitz T, Eriksson L. Transformations and algorithms in a computerized brain atlas. IEEE Trans Nucl Sci. 1993;40:1187-1191.
27. Villemagne VL, Pike KE, Chételat G, et al. Longitudinal assessment of Ab and cognition in aging and Alzheimer disease. Ann Neurol. 2011;69:181-192.
28. Diedrichsen J. A spatially unbiased atlas template of the human cerebellum. Neuroimage. 2006;33:127-138.