Norchloro-fluoro-homoepibatidine (NCFHEB) - A promising radioligand for neuroimaging nicotinic acetylcholine receptors with PET

European Neuropsychopharmacology

Volumn 18, Issue 3, 2008, Pages 222-229

  Deuther Conrad, W ^a   Patt, J T ^a   Lockman, P R ^c   Allen, D D ^d   Patt, M ^b   Schildan, A ^b   Ganapathy, V ^e   Steinbach, J ^a   Sabri, O ^b   Brust, P ^a  

^a Institute of Interdisciplinary Isotope Research   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c TEXAS TECH UNIVERSITY   (United States)

^d NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Blood brain barrier; Epibatidine; Positron emission tomography; Stereoselectivity; Subtype specificity

Indexed keywords

3 (2 AZETIDINYLMETHOXY)PYRIDINE; EPIBATIDINE; FLUORINE 18; NICOTINIC RECEPTOR; NORCHLOROFLUOROHOMOEPIBATIDINE; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERMETHOD COMPARISON; ISOTOPE LABELING; LIGAND BINDING; MOUSE; NEUROIMAGING; NEUROTRANSMISSION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ANIMALS; AZETIDINES; BENZAMIDES; BICYCLO COMPOUNDS, HETEROCYCLIC; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD-BRAIN BARRIER; CHOLINE; FEMALE; INDICATORS AND REAGENTS; ISOTOPE LABELING; MALE; MICE; PERFUSION; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, NICOTINIC; STEREOISOMERISM; TISSUE DISTRIBUTION;

EID: 38149021383     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2007.07.002     Document Type: Article

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