A fully-automated one-pot synthesis of [18F]fluoromethylcholine with reduced dimethylaminoethanol contamination via [18F]fluoromethyl tosylate

Applied Radiation and Isotopes

Volumn 78, Issue , 2013, Pages 26-32

  Rodnick, Melissa E ^a   Brooks, Allen F ^a   Hockley, Brian G ^a   Henderson, Bradford D ^a   Scott, Peter J H ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

18F fluoromethylcholine; Fluorine 18; Positron emission tomography; Prostate cancer imaging

Indexed keywords

[18F]FLUOROMETHYLCHOLINE; CRUDE REACTION MIXTURES; FORMULATED PRODUCTS; LIQUID-PHASE SYNTHESIS; ONE-POT SYNTHESIS; PROSTATE-CANCER IMAGING; QUALITY-CONTROL TESTING; SOLID-PHASE EXTRACTION;

FLUORINE; MEDICAL IMAGING; POSITRON EMISSION TOMOGRAPHY; QUALITY CONTROL; SULFUR COMPOUNDS;

SYNTHESIS (CHEMICAL);

DEANOL; FLUORINE 18; FLUOROMETHYL TOSYLATE F 18; FLUOROMETHYLCHOLINE F 18; RADIOISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; FLUORINATION; IONIZATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PURIFICATION; QUALITY CONTROL; RADIATION DOSE; RADIOISOTOPE DECAY; SOLID PHASE EXTRACTION; STOICHIOMETRY; SYNTHESIS;

CHOLINE; DEANOL; DRUG CONTAMINATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; ISOTOPE LABELING; ROBOTICS;

EID: 84877655266     PISSN: 09698043     EISSN: 18729800     Source Type: Journal    
DOI: 10.1016/j.apradiso.2013.04.017     Document Type: Article

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