메뉴 건너뛰기




Volumn 62, Issue 2, 2014, Pages 87-101

Nicotinic cholinergic signaling in adipose tissue and pancreatic islets biology: Revisited function and therapeutic perspectives

Author keywords

Adipocyte; Diabetes; Islet; nAChR; Nicotine; Obesity

Indexed keywords

ACETYLCHOLINE; BUNGAROTOXIN RECEPTOR; CATION CHANNEL; IONOTROPIC RECEPTOR; NEUROTRANSMITTER; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

EID: 84896544188     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-013-0266-6     Document Type: Review
Times cited : (19)

References (155)
  • 1
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion - implications for health and disease
    • Ahren B (2000) Autonomic regulation of islet hormone secretion - implications for health and disease. Diabetologia 43:393-410
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahren, B.1
  • 2
    • 0022455497 scopus 로고
    • The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog
    • Ahren B, Taborsky GJ Jr (1986) The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog. Endocrinology 118:1551-1557 (Pubitemid 16078534)
    • (1986) Endocrinology , vol.118 , Issue.4 , pp. 1551-1557
    • Ahren, B.1    Taborsky Jr., G.J.2
  • 3
    • 0022552444 scopus 로고
    • Effect and mechanism of vagal nerve stimulation on somatostatin secretion in dogs
    • Ahren B, Paquette TL, Taborsky GJ Jr (1986) Effect and mechanism of vagal nerve stimulation on somatostatin secretion in dogs. Am J Physiol 250(2 Pt 1):E212-E217
    • (1986) Am J Physiol , vol.250 , Issue.2 PART 1
    • Ahren, B.1    Paquette, T.L.2    Taborsky Jr., G.J.3
  • 4
    • 33748071433 scopus 로고    scopus 로고
    • Does maternal smoking during pregnancy have a direct effect on future offspring obesity? Evidence from a prospective birth cohort study
    • DOI 10.1093/aje/kwj209
    • Al Mamun A, Lawlor DA, Alati R et al (2006) Does maternal smoking during pregnancy have a direct effect on future offspring obesity? Evidence from a prospective birth cohort study. Am J Epidemiol 164:317-325 (Pubitemid 44297339)
    • (2006) American Journal of Epidemiology , vol.164 , Issue.4 , pp. 317-325
    • Al, M.A.1    Lawlor, D.A.2    Alati, R.3    O'Callaghan, M.J.4    Williams, G.M.5    Najman, J.M.6
  • 5
    • 0034861532 scopus 로고    scopus 로고
    • Modulation of nicotinic receptor activity in the central nervous system: A novel approach to the treatment of Alzheimer disease
    • Albuquerque EX, Santos MD, Alkondon M et al (2001) Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease. Alzheimer Dis Assoc Disord 15(Suppl 1):S19-S25
    • (2001) Alzheimer Dis Assoc Disord , vol.15 , Issue.SUPPL. 1
    • Albuquerque, E.X.1    Santos, M.D.2    Alkondon, M.3
  • 6
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: From structure to function
    • Albuquerque EX, Pereira EF, Alkondon M et al (2009) Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev 89:73-120
    • (2009) Physiol Rev , vol.89 , pp. 73-120
    • Albuquerque, E.X.1    Pereira, E.F.2    Alkondon, M.3
  • 7
    • 79957563251 scopus 로고    scopus 로고
    • Endocrine disruptors in the etiology of type 2 diabetes mellitus
    • Alonso-Magdalena P, Quesada I, Nadal A (2011) Endocrine disruptors in the etiology of type 2 diabetes mellitus. Nat Rev Endocrinol 7:346-353
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 346-353
    • Alonso-Magdalena, P.1    Quesada, I.2    Nadal, A.3
  • 9
    • 34548501244 scopus 로고    scopus 로고
    • Quantification of PPAR-gamma protein in monocyte/macrophages from healthy smokers and non-smokers: A possible direct effect of nicotine
    • DOI 10.1016/j.lfs.2007.07.017, PII S0024320507005346
    • Amoruso A, Bardelli C, Gunella G et al (2007) Quantification of PPAR-gamma protein in monocyte/macrophages from healthy smokers and non-smokers: a possible direct effect of nicotine. Life Sci 81:906-915 (Pubitemid 47374210)
    • (2007) Life Sciences , vol.81 , Issue.11 , pp. 906-915
    • Amoruso, A.1    Bardelli, C.2    Gunella, G.3    Fresu, L.G.4    Ferrero, V.5    Brunelleschi, S.6
  • 10
    • 34848880141 scopus 로고    scopus 로고
    • Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: A role for oxidant stress
    • DOI 10.1074/jbc.M703701200
    • An Z, Wang H, Song P et al (2007) Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: a role for oxidant stress. J Biol Chem 282:26793-26801 (Pubitemid 47501967)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.37 , pp. 26793-26801
    • An, Z.1    Wang, H.2    Song, P.3    Zhang, M.4    Geng, X.5    Zou, M.-H.6
  • 11
    • 0029084810 scopus 로고
    • Cholinoceptor-mediated effects on glycerol output from human adipose tissue using in situ microdialysis
    • Andersson K, Arner P (1995) Cholinoceptor-mediated effects on glycerol output from human adipose tissue using in situ microdialysis. Br J Pharmacol 115:1155-1162
    • (1995) Br J Pharmacol , vol.115 , pp. 1155-1162
    • Andersson, K.1    Arner, P.2
  • 12
    • 0034896897 scopus 로고    scopus 로고
    • Systemic nicotine stimulates human adipose tissue lipolysis through local cholinergic and catecholaminergic receptors
    • DOI 10.1038/sj.ijo.0801654
    • Andersson K, Arner P (2001) Systemic nicotine stimulates human adipose tissue lipolysis through local cholinergic and catechol-aminergic receptors. Int J Obes Relat Metab Disord 25:1225-1232 (Pubitemid 32721546)
    • (2001) International Journal of Obesity , vol.25 , Issue.8 , pp. 1225-1232
    • Andersson, K.1    Arner, P.2
  • 13
    • 0034988232 scopus 로고    scopus 로고
    • Nicotine infusion alters leptin and uncoupling protein 1 mRNA expression in adipose tissues of rats
    • Arai K, Kim K, Kaneko K et al (2001) Nicotine infusion alters leptin and uncoupling protein 1 mRNA expression in adipose tissues of rats. Am J Physiol Endocrinol Metab 280:E867-E876
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Arai, K.1    Kim, K.2    Kaneko, K.3
  • 15
    • 0018770989 scopus 로고
    • Acute effects of nicotine on plasma free fatty acid concentrations and on the response to cold stress, in lean and obese (genotype ob/ob) mice
    • Batt RA, Topping DL (1979) Acute effects of nicotine on plasma free fatty acid concentrations and on the response to cold stress, in lean and obese (genotype ob/ob) mice. Int J Obes 3:7-13 (Pubitemid 9130052)
    • (1979) International Journal of Obesity , vol.3 , Issue.1 , pp. 7-13
    • Batt, R.A.L.1    Topping, D.L.2
  • 17
    • 1642524372 scopus 로고    scopus 로고
    • Systemic nicotine alters whole-body fat utilization in female rats
    • DOI 10.1016/j.physbeh.2003.10.011
    • Bishop C, Parker GC, Coscina DV (2004) Systemic nicotine alters whole-body fat utilization in female rats. Physiol Behav 80:563-567 (Pubitemid 38117033)
    • (2004) Physiology and Behavior , vol.80 , Issue.4 , pp. 563-567
    • Bishop, C.1    Parker, G.C.2    Coscina, D.V.3
  • 18
    • 21244481615 scopus 로고    scopus 로고
    • Analysis of complex mixtures - Cigarette smoke
    • DOI 10.1016/j.etp.2005.05.010, PII S0940299305000369
    • Borgerding M, Klus H (2005) Analysis of complex mixtures - cigarette smoke. Exp Toxicol Pathol 57(Suppl 1):43-73 (Pubitemid 40884483)
    • (2005) Experimental and Toxicologic Pathology , vol.57 , Issue.SUPPL. 1 , pp. 43-73
    • Borgerding, M.1    Klus, H.2
  • 19
    • 49349093443 scopus 로고    scopus 로고
    • Pharmacological effects of nicotine on norepinephrine metabolism in rat brown adipose tissue: Relevance to nicotinic therapies for smoking cessation
    • Brees DJ, Elwell MR, Tingley FD 3rd et al (2008) Pharmacological effects of nicotine on norepinephrine metabolism in rat brown adipose tissue: relevance to nicotinic therapies for smoking cessation. Toxicol Pathol 36:568-575
    • (2008) Toxicol Pathol , vol.36 , pp. 568-575
    • Brees, D.J.1    Elwell, M.R.2    Tingley III, F.D.3
  • 20
    • 0015848596 scopus 로고
    • Lack of effect of chronic nicotine administration on fatty acid distribution in the liver, testis, and adipose tissue of male Fischer-344 rats
    • Brindis RG, Petersen BJ, Thompson JH et al (1973) Lack of effect of chronic nicotine administration on fatty acid distribution in the liver, testis, and adipose tissue of male Fischer-344 rats. J Lipid Res 14:688-691
    • (1973) J Lipid Res , vol.14 , pp. 688-691
    • Brindis, R.G.1    Petersen, B.J.2    Thompson, J.H.3
  • 21
    • 34547403058 scopus 로고    scopus 로고
    • Fetal and neonatal nicotine exposure and postnatal glucose homeostasis: Identifying critical windows of exposure
    • DOI 10.1677/JOE-07-0050
    • Bruin JE, Kellenberger LD, Gerstein HC et al (2007) Fetal and neonatal nicotine exposure and postnatal glucose homeostasis: identifying critical windows of exposure. J Endocrinol 194:171-178 (Pubitemid 47162896)
    • (2007) Journal of Endocrinology , vol.194 , Issue.1 , pp. 171-178
    • Bruin, J.E.1    Kellenberger, L.D.2    Gerstein, H.C.3    Morrison, K.M.4    Holloway, A.C.5
  • 22
    • 43349101355 scopus 로고    scopus 로고
    • Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria
    • DOI 10.1093/toxsci/kfn012
    • Bruin JE, Gerstein HC, Morrison KM et al (2008a) Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicol Sci 103:362-370 (Pubitemid 351659608)
    • (2008) Toxicological Sciences , vol.103 , Issue.2 , pp. 362-370
    • Bruin, J.E.1    Gerstein, H.C.2    Morrison, K.M.3    Holloway, A.C.4
  • 23
    • 43049176761 scopus 로고    scopus 로고
    • Maternal nicotine exposure increases oxidative stress in the offspring
    • Bruin JE, Petre MA, Lehman MA et al (2008b) Maternal nicotine exposure increases oxidative stress in the offspring. Free Radic Biol Med 44:1919-1925
    • (2008) Free Radic Biol Med , vol.44 , pp. 1919-1925
    • Bruin, J.E.1    Petre, M.A.2    Lehman, M.A.3
  • 24
    • 0037343956 scopus 로고    scopus 로고
    • In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57B1/6J mice
    • DOI 10.1046/j.1471-4159.2003.01640.x
    • Brunzell DH, Russell DS, Picciotto MR (2003) In vivo nicotine treatment regulates mesocorticolimbic CREB and ERK signaling in C57Bl/6 J mice. J Neurochem 84:1431-1441 (Pubitemid 36343609)
    • (2003) Journal of Neurochemistry , vol.84 , Issue.6 , pp. 1431-1441
    • Brunzell, D.H.1    Russell, D.S.2    Picciotto, M.R.3
  • 26
    • 84870998884 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor alpha7 in subcutaneous mature adipocytes: Downregulation in human obesity and modulation by diet-induced weight loss
    • Cancello R, Zulian A, Maestrini S et al (2012) The nicotinic acetylcholine receptor alpha7 in subcutaneous mature adipocytes: downregulation in human obesity and modulation by diet-induced weight loss. Int J Obes 36:1552-1557
    • (2012) Int J Obes , vol.36 , pp. 1552-1557
    • Cancello, R.1    Zulian, A.2    Maestrini, S.3
  • 27
    • 80055002865 scopus 로고    scopus 로고
    • Islet organogenesis, angiogenesis and innervation
    • Cerf ME (2011) Islet organogenesis, angiogenesis and innervation. Cell Biol Int 35:1065-1078
    • (2011) Cell Biol Int , vol.35 , pp. 1065-1078
    • Cerf, M.E.1
  • 28
    • 0023179016 scopus 로고
    • The effect of acute and chronic administration of nicotine on lipoprotein lipase activity
    • Chajek-Shaul T, Friedman G, Dabach Y et al (1987) The effect of acute and chronic administration of nicotine on lipoprotein lipase activity. Int Angiol 6:29-36 (Pubitemid 17110190)
    • (1987) International Angiology , vol.6 , Issue.1 , pp. 29-36
    • Chajek-Shaul, T.1    Friedman, G.2    Dabach, Y.3
  • 29
    • 0025610842 scopus 로고
    • The TiPS lecture. The nicotinic acetylcholine receptor: An allosteric protein prototype of ligand-gated ion channels
    • Changeux JP (1990) The TiPS lecture. The nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels. Trends Pharmacol Sci 11:485-492
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 485-492
    • Changeux, J.P.1
  • 30
    • 84870042685 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor: The founding father of the pentameric ligand-gated ion channel superfamily
    • Changeux JP (2012) The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily. J Biol Chem 287:40207-40215
    • (2012) J Biol Chem , vol.287 , pp. 40207-40215
    • Changeux, J.P.1
  • 31
    • 0014936960 scopus 로고
    • Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine
    • Changeux JP, Kasai M, Huchet M et al (1970) Extraction from electric tissue of gymnotus of a protein presenting several typical properties characteristic of the physiological receptor of acetylcholine. C R Acad Sci Hebd Seances Acad Sci D 270:2864-2867
    • (1970) C R Acad Sci Hebd Seances Acad Sci D , vol.270 , pp. 2864-2867
    • Changeux, J.P.1    Kasai, M.2    Huchet, M.3
  • 33
    • 84865484612 scopus 로고    scopus 로고
    • The adipose organ at a glance
    • Cinti S (2012) The adipose organ at a glance. Dis Mod Mech 5:588-594
    • (2012) Dis Mod Mech , vol.5 , pp. 588-594
    • Cinti, S.1
  • 34
    • 0034732218 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors in non-neuronal cells: New mediators of tobacco toxicity?
    • DOI 10.1016/S0014-2999(00)00036-4, PII S0014299900000364
    • Conti-Fine BM, Navaneetham D, Lei S et al (2000) Neuronal nicotinic receptors in non-neuronal cells: new mediators of tobacco toxicity? Eur J Pharmacol 393:279-294 (Pubitemid 30193427)
    • (2000) European Journal of Pharmacology , vol.393 , Issue.1-3 , pp. 279-294
    • Conti-Fine, B.M.1    Navaneetham, D.2    Lei, S.3    Maus, A.D.J.4
  • 35
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • Cypess AM, Lehman S, Williams G et al (2009) Identification and importance of brown adipose tissue in adult humans. N Engl J Med 360:1509-1517
    • (2009) N Engl J Med , vol.360 , pp. 1509-1517
    • Cypess, A.M.1    Lehman, S.2    Williams, G.3
  • 36
    • 0036488178 scopus 로고    scopus 로고
    • Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones
    • DOI 10.1046/j.0022-3042.2001.00725.x
    • Dajas-Bailador FA, Soliakov L, Wonnacott S (2002) Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurons. J Neurochem 80:520-530 (Pubitemid 36383035)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.3 , pp. 520-530
    • Dajas-Bailador, F.A.1    Soliakov, L.2    Wonnacott, S.3
  • 38
    • 77953816890 scopus 로고    scopus 로고
    • Neonatal nicotine exposure causes insulin and leptin resistance and inhibits hypothalamic leptin signaling in adult rat offspring
    • de Oliveira E, Moura EG, Santos-Silva AP et al (2010) Neonatal nicotine exposure causes insulin and leptin resistance and inhibits hypothalamic leptin signaling in adult rat offspring. J Endocrinol 206:55-63
    • (2010) J Endocrinol , vol.206 , pp. 55-63
    • De Oliveira, E.1    Moura, E.G.2    Santos-Silva, A.P.3
  • 39
    • 84857189813 scopus 로고    scopus 로고
    • Expression of the non-neuronal cholinergic system in rat beta-cells
    • Delbro DS (2012) Expression of the non-neuronal cholinergic system in rat beta-cells. Auton Neurosci 167:75-77
    • (2012) Auton Neurosci , vol.167 , pp. 75-77
    • Delbro, D.S.1
  • 40
    • 84856644589 scopus 로고    scopus 로고
    • Overview of muscarinic receptor subtypes
    • Eglen RM (2012) Overview of muscarinic receptor subtypes. Hand Exp Pharmacol 208:3-28
    • (2012) Hand Exp Pharmacol , vol.208 , pp. 3-28
    • Eglen, R.M.1
  • 41
    • 0024520156 scopus 로고
    • Participation of nicotinic receptor in hormone release from isolated rat islets of Langerhans
    • DOI 10.1016/0168-8227(89)90057-0
    • Ejiri K, Taniguchi H, Baba S (1989) Participation of nicotinic receptor in hormone release from isolated rat islets of Langerhans. Diabetes Res Clin Pract 6:53-59 (Pubitemid 19021835)
    • (1989) Diabetes Research and Clinical Practice , vol.6 , Issue.1 , pp. 53-59
    • Ejiri, K.1    Taniguchi, H.2    Baba, S.3
  • 42
    • 0025318492 scopus 로고
    • Possible involvement of cholinergic nicotinic receptor in insulin release from isolated rat islets
    • DOI 10.1016/0168-8227(90)90117-C
    • Ejiri K, Taniguchi GH, Ishihara K et al (1990) Possible involvement of cholinergic nicotinic receptor in insulin release from isolated rat islets. Diabetes Res Clin Pract 8:193-199 (Pubitemid 20111443)
    • (1990) Diabetes Research and Clinical Practice , vol.8 , Issue.3 , pp. 193-199
    • Ejiri, K.1    Taniguchi, H.2    Ishihara, K.3    Hara, Y.4    Baba, S.5
  • 43
    • 0030855617 scopus 로고    scopus 로고
    • No acute effects of smoking and nicotine nasal spray on lipolysis measured by subcutaneous microdialysis
    • Eliasson B, Smith U, Lonnroth P (1997) No acute effects of smoking and nicotine nasal spray on lipolysis measured by subcutaneous microdialysis. Eur J Clin Investig 27:503-509 (Pubitemid 27288361)
    • (1997) European Journal of Clinical Investigation , vol.27 , Issue.6 , pp. 503-509
    • Eliasson, B.1    Smith, U.2    Lonnroth, P.3
  • 44
    • 77950190436 scopus 로고    scopus 로고
    • Distribution and development of brown adipocytes in the murine and human adipose organ
    • Frontini A, Cinti S (2010) Distribution and development of brown adipocytes in the murine and human adipose organ. Cell Metab 11:253-256
    • (2010) Cell Metab , vol.11 , pp. 253-256
    • Frontini, A.1    Cinti, S.2
  • 45
    • 0035890160 scopus 로고    scopus 로고
    • Norepinephrine secretion in the hypothalamic paraventricular nucleus of rats during unlimited access to self-administered nicotine: An in vivo microdialysis study
    • Fu Y, Matta SG, Brower VG et al (2001) Norepinephrine secretion in the hypothalamic paraventricular nucleus of rats during unlimited access to self-administered nicotine: an in vivo microdialysis study. J Neurosci 21:8979-8989 (Pubitemid 33054859)
    • (2001) Journal of Neuroscience , vol.21 , Issue.22 , pp. 8979-8989
    • Fu, Y.1    Matta, S.G.2    Brower, V.G.3    Sharp, B.M.4
  • 46
    • 33747125503 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells
    • Gahring LC, Rogers SW (2005) Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells. AAPS J 7:E885-E894
    • (2005) AAPS J , vol.7
    • Gahring, L.C.1    Rogers, S.W.2
  • 47
    • 26444508566 scopus 로고    scopus 로고
    • Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function
    • Gao YJ, Holloway AC, Zeng ZH et al (2005) Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function. Obes Res 13:687-692
    • (2005) Obes Res , vol.13 , pp. 687-692
    • Gao, Y.J.1    Holloway, A.C.2    Zeng, Z.H.3
  • 48
    • 84857132887 scopus 로고    scopus 로고
    • 2+ accumulation and cytochrome c release: Study on isolated mitochondria
    • 2+ accumulation and cytochrome c release: study on isolated mitochondria. PLoS ONE 7:e31361
    • (2012) PLoS ONE , vol.7
    • Gergalova, G.1    Lykhmus, O.2    Kalashnyk, O.3
  • 49
    • 0034786750 scopus 로고    scopus 로고
    • Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function
    • DOI 10.1210/er.22.5.565
    • Gilon P, Henquin JC (2001) Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr Rev 22:565-604 (Pubitemid 32958576)
    • (2001) Endocrine Reviews , vol.22 , Issue.5 , pp. 565-604
    • Gilon, P.1    Henquin, J.-C.2
  • 50
    • 1942453708 scopus 로고    scopus 로고
    • The developmental origins of the metabolic syndrome
    • DOI 10.1016/j.tem.2004.03.002, PII S1043276004000578
    • Gluckman PD, Hanson MA (2004) The developmental origins of the metabolic syndrome. Trends Endocrinol Metab 15:183-187 (Pubitemid 38510499)
    • (2004) Trends in Endocrinology and Metabolism , vol.15 , Issue.4 , pp. 183-187
    • Gluckman, P.D.1    Hanson, M.A.2
  • 51
    • 84867898753 scopus 로고    scopus 로고
    • Tnfalpha, Cox2 and AdipoQ adipokine gene expression levels are modulated in murine adipose tissues by both nicotine and nACh receptors containing the beta2 subunit
    • Gochberg-Sarver A, Kedmi M, Gana-Weisz M et al (2012) Tnfalpha, Cox2 and AdipoQ adipokine gene expression levels are modulated in murine adipose tissues by both nicotine and nACh receptors containing the beta2 subunit. Mol Genet Metab 107:561-570
    • (2012) Mol Genet Metab , vol.107 , pp. 561-570
    • Gochberg-Sarver, A.1    Kedmi, M.2    Gana-Weisz, M.3
  • 52
    • 0016774315 scopus 로고
    • Enzymes of the cholinergic system in islets of Langerhans
    • Godfrey DA, Matschinsky FM (1975) Enzymes of the cholinergic system in islets of Langerhans. J Histochem Cytochem 23:645-651
    • (1975) J Histochem Cytochem , vol.23 , pp. 645-651
    • Godfrey, D.A.1    Matschinsky, F.M.2
  • 53
    • 0032424694 scopus 로고    scopus 로고
    • Transcription factor STAT3 in leptin target neurons of the rat hypothalamus
    • Hakansson ML, Meister B (1998) Transcription factor STAT3 in leptin target neurons of the rat hypothalamus. Neuroendocrinology 68:420-427
    • (1998) Neuroendocrinology , vol.68 , pp. 420-427
    • Hakansson, M.L.1    Meister, B.2
  • 54
    • 0026772772 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis
    • Hales CN, Barker DJ (1992) Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35:595-601
    • (1992) Diabetologia , vol.35 , pp. 595-601
    • Hales, C.N.1    Barker, D.J.2
  • 55
    • 84862130670 scopus 로고    scopus 로고
    • The adipocyte as an endocrine organ in the regulation of metabolic homeostasis
    • Harwood HJ Jr (2012) The adipocyte as an endocrine organ in the regulation of metabolic homeostasis. Neuropharmacology 63:57-75
    • (2012) Neuropharmacology , vol.63 , pp. 57-75
    • Harwood Jr., H.J.1
  • 57
    • 28444469821 scopus 로고    scopus 로고
    • Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes
    • DOI 10.1007/s00125-005-0022-5
    • Holloway AC, Lim GE, Petrik JJ et al (2005) Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes. Diabetologia 48:2661-2666 (Pubitemid 41738235)
    • (2005) Diabetologia , vol.48 , Issue.12 , pp. 2661-2666
    • Holloway, A.C.1    Lim, G.E.2    Petrik, J.J.3    Foster, W.G.4    Morrison, K.M.5    Gerstein, H.C.6
  • 58
    • 35348881464 scopus 로고    scopus 로고
    • Transgenerational effects of fetal and neonatal exposure to nicotine
    • DOI 10.1007/s12020-007-0043-6
    • Holloway AC, Cuu DQ, Morrison KM et al (2007) Transgenerational effects of fetal and neonatal exposure to nicotine. Endocrine 31:254-259 (Pubitemid 47574977)
    • (2007) Endocrine , vol.31 , Issue.3 , pp. 254-259
    • Holloway, A.C.1    Cuu, D.Q.2    Morrison, K.M.3    Gerstein, H.C.4    Tarnopolsky, M.A.5
  • 59
    • 80052358867 scopus 로고    scopus 로고
    • Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: Similarities and differences
    • Huang H, Xu Y, van den Pol AN (2011) Nicotine excites hypothalamic arcuate anorexigenic proopiomelanocortin neurons and orexigenic neuropeptide Y neurons: similarities and differences. J Neurophysiol 106:1191-1202
    • (2011) J Neurophysiol , vol.106 , pp. 1191-1202
    • Huang, H.1    Xu, Y.2    Van Den Pol, A.N.3
  • 60
    • 84861074503 scopus 로고    scopus 로고
    • Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase-Akt pathways
    • Huang X, Cheng Z, Su Q et al (2012) Neuroprotection by nicotine against colchicine-induced apoptosis is mediated by PI3-kinase-Akt pathways. Int J Neurosci 122:324-332
    • (2012) Int J Neurosci , vol.122 , pp. 324-332
    • Huang, X.1    Cheng, Z.2    Su, Q.3
  • 61
    • 0015720965 scopus 로고
    • Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue
    • Hucho F, Changeux JP (1973) Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue. FEBS Lett 38:11-15
    • (1973) FEBS Lett , vol.38 , pp. 11-15
    • Hucho, F.1    Changeux, J.P.2
  • 62
    • 84872295116 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors: From basic science to therapeutics
    • Hurst R, Rollema H, Bertrand D (2013) Nicotinic acetylcholine receptors: from basic science to therapeutics. Pharmacol Ther 137:22-54
    • (2013) Pharmacol Ther , vol.137 , pp. 22-54
    • Hurst, R.1    Rollema, H.2    Bertrand, D.3
  • 63
    • 33749440087 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors
    • DOI 10.2174/138161206778522056
    • Ishii M, Kurachi Y (2006) Muscarinic acetylcholine receptors. Curr Pharm Des 12:3573-3581 (Pubitemid 44509627)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.28 , pp. 3573-3581
    • Ishii, M.1    Kurachi, Y.2
  • 64
    • 0037469947 scopus 로고    scopus 로고
    • Nicotine administration decreases neuropeptide Y expression and increases leptin receptor expression in the hypothalamus of food-deprived rats
    • Jang MH, Shin MC, Kim KH et al (2003) Nicotine administration decreases neuropeptide Y expression and increases leptin receptor expression in the hypothalamus of food-deprived rats. Brain Res 964:311-315
    • (2003) Brain Res , vol.964 , pp. 311-315
    • Jang, M.H.1    Shin, M.C.2    Kim, K.H.3
  • 65
    • 0036890823 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated effects on appetite and food intake
    • DOI 10.1002/neu.10147
    • Jo YH, Talmage DA, Role LW (2002) Nicotinic receptor-mediated effects on appetite and food intake. J Neurobiol 53:618-632 (Pubitemid 35375591)
    • (2002) Journal of Neurobiology , vol.53 , Issue.4 , pp. 618-632
    • Jo, Y.-H.1    Talmage, D.A.2    Role, L.W.3
  • 66
    • 29144499110 scopus 로고    scopus 로고
    • Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice
    • DOI 10.1523/JNEUROSCI.3638-05.2005
    • Jo YH, Wiedl D, Role LW (2005) Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice. J Neurosci 25:11133-11144 (Pubitemid 43089558)
    • (2005) Journal of Neuroscience , vol.25 , Issue.48 , pp. 11133-11144
    • Jo, Y.-H.1    Wiedl, D.2    Role, L.W.3
  • 67
    • 0033752964 scopus 로고    scopus 로고
    • Nicotine up-regulates expression of orexin and its receptors in rat brain
    • Kane JK, Parker SL, Matta SG et al (2000) Nicotine up-regulates expression of orexin and its receptors in rat brain. Endocrinology 141:3623-3629
    • (2000) Endocrinology , vol.141 , pp. 3623-3629
    • Kane, J.K.1    Parker, S.L.2    Matta, S.G.3
  • 68
    • 0035951685 scopus 로고    scopus 로고
    • Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat
    • DOI 10.1016/S0304-3940(00)01730-4, PII S0304394000017304
    • Kane JK, Parker SL, Li MD (2001) Hypothalamic orexin-A binding sites are downregulated by chronic nicotine treatment in the rat. Neurosci Lett 298:1-4 (Pubitemid 32057200)
    • (2001) Neuroscience Letters , vol.298 , Issue.1 , pp. 1-4
    • Kane, J.K.1    Parker, S.L.2    Li, M.D.3
  • 69
    • 0035957946 scopus 로고    scopus 로고
    • Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • Kihara T, Shimohama S, Sawada H et al (2001) Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 276:13541-13546
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3
  • 70
    • 50249107978 scopus 로고    scopus 로고
    • Association of CHRNA2 polymorphisms with overweight/obesity and clinical characteristics in a Korean population
    • Kim J (2008) Association of CHRNA2 polymorphisms with overweight/obesity and clinical characteristics in a Korean population. Clin Chem Lab Med 46:1085-1089
    • (2008) Clin Chem Lab Med , vol.46 , pp. 1085-1089
    • Kim, J.1
  • 71
    • 84860845827 scopus 로고    scopus 로고
    • The use of animal models in diabetes research
    • King AJ (2012) The use of animal models in diabetes research. Br J Pharmacol 166:877-894
    • (2012) Br J Pharmacol , vol.166 , pp. 877-894
    • King, A.J.1
  • 72
    • 0031963193 scopus 로고    scopus 로고
    • Immunohistochemical localization of nicotinic acetylcholine receptors in the guinea bowel and pancreas
    • DOI 10.1002/(SICI)1096-9861(19980126)390:4<497::AI
    • Kirchgessner AL, Liu MT (1998) Immunohistochemical localization of nicotinic acetylcholine receptors in the guinea pig bowel and pancreas. J Comp Neurol 390:497-514 (Pubitemid 28055941)
    • (1998) Journal of Comparative Neurology , vol.390 , Issue.4 , pp. 497-514
    • Kirchgessner, A.L.1    Liu, M.-T.2
  • 74
    • 38149101548 scopus 로고    scopus 로고
    • Social and early-life determinants of overweight and obesity in 18-year-old Swedish men
    • Koupil I, Toivanen P (2008) Social and early-life determinants of overweight and obesity in 18-year-old Swedish men. Int J Obes 32:73-81
    • (2008) Int J Obes , vol.32 , pp. 73-81
    • Koupil, I.1    Toivanen, P.2
  • 75
    • 79960891073 scopus 로고    scopus 로고
    • Anti-inflammatory effects of nicotine in obesity and ulcerative colitis
    • Lakhan SE, Kirchgessner A (2011) Anti-inflammatory effects of nicotine in obesity and ulcerative colitis. J Transl Med 9:129
    • (2011) J Transl Med , vol.9 , pp. 129
    • Lakhan, S.E.1    Kirchgessner, A.2
  • 76
    • 33748754785 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells
    • DOI 10.1210/en.2006-0456
    • Laychock SG, Sessanna SM, Lin MH et al (2006) Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells. Endocrinology 147:4705-4712 (Pubitemid 44402178)
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4705-4712
    • Laychock, S.G.1    Sessanna, S.M.2    Lin, M.-H.3    Mastrandrea, L.D.4
  • 77
    • 0028922693 scopus 로고
    • Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
    • Le Novere N, Changeux JP (1995) Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells. J Mol Evol 40:155-172
    • (1995) J Mol Evol , vol.40 , pp. 155-172
    • Le Novere, N.1    Changeux, J.P.2
  • 78
    • 22944485985 scopus 로고    scopus 로고
    • Fetal nicotinic overload, blunted sympathetic responsivity, and obesity
    • Levin ED (2005) Fetal nicotinic overload, blunted sympathetic responsivity, and obesity. Birth Defects Res A Clin Mol Teratol 73:481-484
    • (2005) Birth Defects Res a Clin Mol Teratol , vol.73 , pp. 481-484
    • Levin, E.D.1
  • 79
    • 0142090719 scopus 로고    scopus 로고
    • Effect of nicotine on the expression of leptin and forebrain leptin receptors in the rat
    • DOI 10.1016/j.brainres.2003.08.024
    • Li MD, Kane JK (2003) Effect of nicotine on the expression of leptin and forebrain leptin receptors in the rat. Brain Res 991:222-231 (Pubitemid 37297951)
    • (2003) Brain Research , vol.991 , Issue.1-2 , pp. 222-231
    • Li, M.D.1    Kane, J.K.2
  • 80
    • 0034625462 scopus 로고    scopus 로고
    • Nicotine administration enhances NPY expression in the rat hypothalamus
    • DOI 10.1016/S0006-8993(00)02283-6, PII S0006899300022836
    • Li MD, Kane JK, Parker SL et al (2000a) Nicotine administration enhances NPY expression in the rat hypothalamus. Brain Res 867:157-164 (Pubitemid 30317392)
    • (2000) Brain Research , vol.867 , Issue.1-2 , pp. 157-164
    • Li, M.D.1    Kane, J.K.2    Parker, S.L.3    McAllen, K.4    Matta, S.G.5    Sharp, B.M.6
  • 81
    • 0034971238 scopus 로고    scopus 로고
    • Regulation of feeding-associated peptides and receptors by nicotine
    • Li MD, Parker SL, Kane JK (2000b) Regulation of feeding-associated peptides and receptors by nicotine. Mol Neurobiol 22:143-165
    • (2000) Mol Neurobiol , vol.22 , pp. 143-165
    • Li, M.D.1    Parker, S.L.2    Kane, J.K.3
  • 82
    • 0029690580 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors
    • Lindstrom J (1996) Neuronal nicotinic acetylcholine receptors. Ion Channels 4:377-450
    • (1996) Ion Channels , vol.4 , pp. 377-450
    • Lindstrom, J.1
  • 83
    • 0035187994 scopus 로고    scopus 로고
    • Oral nicotine administration decreases tumor necrosis factor-alpha expression in fat tissues in obese rats
    • DOI 10.1053/meta.2001.19436
    • Liu RH, Kurose T, Matsukura S (2001) Oral nicotine administration decreases tumor necrosis factor-alpha expression in fat tissues in obese rats. Metabolism 50:79-85 (Pubitemid 32058553)
    • (2001) Metabolism: Clinical and Experimental , vol.50 , Issue.1 , pp. 79-85
    • Liu, R.1    Kurose, T.2    Matsukura, S.3
  • 84
    • 0037223501 scopus 로고    scopus 로고
    • Long-term oral nicotine administration reduces insulin resistance in obese rats
    • DOI 10.1016/S0014-2999(02)02726-7, PII S0014299902027267
    • Liu RH, Mizuta M, Matsukura S (2003) Long-term oral nicotine administration reduces insulin resistance in obese rats. Eur J Pharmacol 458:227-234 (Pubitemid 36050724)
    • (2003) European Journal of Pharmacology , vol.458 , Issue.1-2 , pp. 227-234
    • Liu, R.-H.1    Mizuta, M.2    Matsukura, S.3
  • 85
    • 3042548823 scopus 로고    scopus 로고
    • The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes
    • DOI 10.1124/jpet.103.065037
    • Liu RH, Mizuta M, Matsukura S (2004) The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes. J Pharmacol Exp Ther 310:52-58 (Pubitemid 38812694)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.310 , Issue.1 , pp. 52-58
    • Liu, R.-H.1    Mizuta, M.2    Matsukura, S.3
  • 86
    • 0034611678 scopus 로고    scopus 로고
    • Towards a molecular understanding of adaptive thermogenesis
    • Lowell BB, Spiegelman BM (2000) Towards a molecular understanding of adaptive thermogenesis. Nature 404:652-660 (Pubitemid 30205070)
    • (2000) Nature , vol.404 , Issue.6778 , pp. 652-660
    • Lowell, B.B.1    Spiegelman, B.M.2
  • 87
    • 0020375715 scopus 로고
    • Cholinergic muscarinic effects on insulin release in mice
    • Lundquist I (1982) Cholinergic muscarinic effects on insulin release in mice. Pharmacology 25:338-347
    • (1982) Pharmacology , vol.25 , pp. 338-347
    • Lundquist, I.1
  • 88
    • 0023854733 scopus 로고
    • Nicotine increases thermogenesis in brown adipose tissue in rats
    • Lupien JR, Bray GA (1988) Nicotine increases thermogenesis in brown adipose tissue in rats. Pharmacol Biochem Behav 29:33-37 (Pubitemid 18052711)
    • (1988) Pharmacology Biochemistry and Behavior , vol.29 , Issue.1 , pp. 33-37
    • Lupien, J.R.1    Bray, G.A.2
  • 90
    • 63449122226 scopus 로고    scopus 로고
    • Nicotine suppresses energy storage through activation of sympathetic outflow to brown adipose tissue via corticotropin-releasing factor type 1 receptor
    • Mano-Otagiri A, Iwasaki-Sekino A, Ohata H et al (2009) Nicotine suppresses energy storage through activation of sympathetic outflow to brown adipose tissue via corticotropin-releasing factor type 1 receptor. Neurosci Lett 455:26-29
    • (2009) Neurosci Lett , vol.455 , pp. 26-29
    • Mano-Otagiri, A.1    Iwasaki-Sekino, A.2    Ohata, H.3
  • 91
    • 73949111377 scopus 로고    scopus 로고
    • An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes
    • Marrero MB, Lucas R, Salet C et al (2010) An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes. J Pharmacol Exp Ther 332:173-180
    • (2010) J Pharmacol Exp Ther , vol.332 , pp. 173-180
    • Marrero, M.B.1    Lucas, R.2    Salet, C.3
  • 93
    • 84859557325 scopus 로고    scopus 로고
    • Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase
    • Martinez de Morentin PB, Whittle AJ, Ferno J et al (2012) Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes 61:807-817
    • (2012) Diabetes , vol.61 , pp. 807-817
    • Martinez De Morentin, P.B.1    Whittle, A.J.2    Ferno, J.3
  • 94
    • 0033781030 scopus 로고    scopus 로고
    • Hypothalamic dopamine and serotonin in the regulation of food intake
    • Meguid MM, Fetissov SO, Varma M et al (2000) Hypothalamic dopamine and serotonin in the regulation of food intake. Nutrition 16:843-857
    • (2000) Nutrition , vol.16 , pp. 843-857
    • Meguid, M.M.1    Fetissov, S.O.2    Varma, M.3
  • 95
    • 0037192850 scopus 로고    scopus 로고
    • Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor
    • DOI 10.1074/jbc.M106744200
    • Meyer EL, Gahring LC, Rogers SW (2002) Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor. J Biol Chem 277:10869-10875 (Pubitemid 34952841)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.13 , pp. 10869-10875
    • Meyer, E.L.1    Gahring, L.C.2    Rogers, S.W.3
  • 96
    • 0344765458 scopus 로고    scopus 로고
    • Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons
    • DOI 10.1016/S0028-3908(98)00074-4, PII S0028390898000744
    • Minana MD, Montoliu C, Llansola M et al (1998) Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons. Neuropharmacology 37:847-857 (Pubitemid 28375752)
    • (1998) Neuropharmacology , vol.37 , Issue.7 , pp. 847-857
    • Minana, M.-D.1    Montoliu, C.2    Llansola, M.3    Grisolia, S.4    Felipo, V.5
  • 97
    • 79958702575 scopus 로고    scopus 로고
    • Nicotine decreases food intake through activation of POMC neurons
    • Mineur YS, Abizaid A, Rao Y et al (2011) Nicotine decreases food intake through activation of POMC neurons. Science 332:1330-1332
    • (2011) Science , vol.332 , pp. 1330-1332
    • Mineur, Y.S.1    Abizaid, A.2    Rao, Y.3
  • 98
    • 39149140708 scopus 로고    scopus 로고
    • Association of maternal lifestyles including smoking during pregnancy with childhood obesity
    • DOI 10.1038/oby.2007.373
    • Mizutani T, Suzuki K, Kondo N et al (2007) Association of maternal lifestyles including smoking during pregnancy with childhood obesity. Obesity 15:3133-3139 (Pubitemid 351256677)
    • (2007) Obesity , vol.15 , Issue.12 , pp. 3133-3139
    • Mizutani, T.1    Suzuki, K.2    Kondo, N.3    Yamagata, Z.4
  • 99
    • 0037021827 scopus 로고    scopus 로고
    • Smoking during pregnancy and diabetes mellitus in a British longitudinal birth cohort
    • Montgomery SM, Ekbom A (2002) Smoking during pregnancy and diabetes mellitus in a British longitudinal birth cohort. BMJ 324:26-27 (Pubitemid 34048849)
    • (2002) British Medical Journal , vol.324 , Issue.7328 , pp. 26-27
    • Montgomery, S.M.1    Ekbom, A.2
  • 100
    • 16444379113 scopus 로고    scopus 로고
    • Smoking during pregnancy and preterm birth according to obstetric history: French national perinatal surveys
    • Nabet C, Ancel PY, Burguet A et al (2005) Smoking during pregnancy and preterm birth according to obstetric history: French national perinatal surveys. Paediatr Perinat Epidemiol 19:88-96 (Pubitemid 40477229)
    • (2005) Paediatric and Perinatal Epidemiology , vol.19 , Issue.2 , pp. 88-96
    • Nabet, C.1    Ancel, P.-Y.2    Burguet, A.3    Kaminski, M.4
  • 101
    • 0036906212 scopus 로고    scopus 로고
    • Nicotine-induced phosphorylation of Akt through epidermal growth factor receptor and Src in PC12h cells
    • DOI 10.1046/j.1471-4159.2002.01248.x
    • Nakayama H, Numakawa T, Ikeuchi T (2002) Nicotine-induced phosphorylation of Akt through epidermal growth factor receptor and Src in PC12 h cells. J Neurochem 83:1372-1379 (Pubitemid 35477476)
    • (2002) Journal of Neurochemistry , vol.83 , Issue.6 , pp. 1372-1379
    • Nakayama, H.1    Numakawa, T.2    Ikeuchi, T.3
  • 102
    • 0025106279 scopus 로고
    • Prenatal nicotine exposure impairs beta-adrenergic function: Persistent chronotropic subsensitivity despite recovery from deficits in receptor binding
    • DOI 10.1016/0361-9230(90)90066-9
    • Navarro HA, Mills E, Seidler FJ et al (1990) Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding. Brain Res Bull 25:233-237 (Pubitemid 20277310)
    • (1990) Brain Research Bulletin , vol.25 , Issue.2 , pp. 233-237
    • Navarro, H.A.1    Mills, E.2    Seidler, F.J.3    Baker, F.E.4    Lappi, S.E.5    Tayyeb, M.I.6    Spencer, J.R.7    Slotkin, T.A.8
  • 103
    • 82555186955 scopus 로고    scopus 로고
    • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
    • Nguyen KD, Qiu Y, Cui X et al (2011) Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature 480:104-108
    • (2011) Nature , vol.480 , pp. 104-108
    • Nguyen, K.D.1    Qiu, Y.2    Cui, X.3
  • 104
    • 0023274082 scopus 로고
    • Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat
    • Nishi S, Seino Y, Ishida H et al (1987) Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat. J Clin Investig 79:1191-1196 (Pubitemid 17065501)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.4 , pp. 1191-1196
    • Nishi, S.1    Seino, Y.2    Ishida, H.3
  • 106
    • 33644846295 scopus 로고    scopus 로고
    • Mouse beta-TC6 insulinoma cells: High expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release
    • DOI 10.1124/mol.105.014902
    • Ohtani M, Oka T, Badyuk M et al (2006) Mouse beta-TC6 insulinoma cells: high expression of functional alpha3beta4 nicotinic receptors mediating membrane potential, intracellular calcium, and insulin release. Mol Pharmacol 69:899-907 (Pubitemid 43363864)
    • (2006) Molecular Pharmacology , vol.69 , Issue.3 , pp. 899-907
    • Ohtani, M.1    Oka, T.2    Badyuk, M.3    Xiao, Y.4    Kellar, K.J.5    Daly, J.W.6
  • 107
    • 58949098280 scopus 로고    scopus 로고
    • Co-existence of muscarinic and nicotinic receptors and their functional interaction in mouse beta-TC6 cells
    • Ohtani M, Daly JW, Oka T (2009) Co-existence of muscarinic and nicotinic receptors and their functional interaction in mouse beta-TC6 cells. Eur J Pharmacol 604:150-157
    • (2009) Eur J Pharmacol , vol.604 , pp. 150-157
    • Ohtani, M.1    Daly, J.W.2    Oka, T.3
  • 108
    • 69549126289 scopus 로고    scopus 로고
    • The inflammatory reflex and the role of complementary and alternative medical therapies
    • Oke SL, Tracey KJ (2009) The inflammatory reflex and the role of complementary and alternative medical therapies. Ann N Y Acad Sci 1172:172-180
    • (2009) Ann N Y Acad Sci , vol.1172 , pp. 172-180
    • Oke, S.L.1    Tracey, K.J.2
  • 109
    • 0033472747 scopus 로고    scopus 로고
    • The effect of nicotine on developing brain catecholamine systems
    • Oliff HS, Gallardo KA (1999) The effect of nicotine on developing brain catecholamine systems. Front Biosci 4:D883-D897
    • (1999) Front Biosci , vol.4
    • Oliff, H.S.1    Gallardo, K.A.2
  • 110
    • 77950641712 scopus 로고    scopus 로고
    • Nicotine exposure affects mother's and pup's nutritional, biochemical, and hormonal profiles during lactation in rats
    • Oliveira E, Pinheiro CR, Santos-Silva AP et al (2010) Nicotine exposure affects mother's and pup's nutritional, biochemical, and hormonal profiles during lactation in rats. J Endocrinol 205:159-170
    • (2010) J Endocrinol , vol.205 , pp. 159-170
    • Oliveira, E.1    Pinheiro, C.R.2    Santos-Silva, A.P.3
  • 111
    • 85028288395 scopus 로고    scopus 로고
    • Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: Longitudinal birth cohort study and analysis
    • DOI 10.1203/01.PDR.0000036602.81878.6D
    • Ong KK, Preece MA, Emmett PM et al (2002) Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis. Pediatr Res 52:863-867 (Pubitemid 35379465)
    • (2002) Pediatric Research , vol.52 , Issue.6 , pp. 863-867
    • Ong, K.K.L.1    Preece, M.A.2    Emmett, P.M.3    Ahmed, M.L.4    Dunger, D.B.5
  • 112
    • 84860453355 scopus 로고    scopus 로고
    • Novel approaches to study the involvement of alpha7-nAChR in human diseases
    • Palma E, Conti L, Roseti C et al (2012) Novel approaches to study the involvement of alpha7-nAChR in human diseases. Curr Drug Targets 13:579-586
    • (2012) Curr Drug Targets , vol.13 , pp. 579-586
    • Palma, E.1    Conti, L.2    Roseti, C.3
  • 113
    • 77950923285 scopus 로고    scopus 로고
    • Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: Implications for mechanisms of nicotine-induced activation of orexin neurons
    • Pasumarthi RK, Fadel J (2010) Stimulation of lateral hypothalamic glutamate and acetylcholine efflux by nicotine: implications for mechanisms of nicotine-induced activation of orexin neurons. J Neurochem 113:1023-1035
    • (2010) J Neurochem , vol.113 , pp. 1023-1035
    • Pasumarthi, R.K.1    Fadel, J.2
  • 115
    • 0036106163 scopus 로고    scopus 로고
    • Fetal environment and subsequent obesity: A study of maternal smoking
    • Power C, Jefferis BJ (2002) Fetal environment and subsequent obesity: a study of maternal smoking. Int J Epidemiol 31:413-419 (Pubitemid 34537801)
    • (2002) International Journal of Epidemiology , vol.31 , Issue.2 , pp. 413-419
    • Power, C.1    Jefferis, B.J.M.H.2
  • 116
    • 0033616266 scopus 로고    scopus 로고
    • The Nobel chronicles. 1936: Henry Hallett Dale (1875-1968) and Otto Loewi (1873-1961)
    • Raju TN (1999) The Nobel chronicles. 1936: Henry Hallett Dale (1875-1968) and Otto Loewi (1873-1961). Lancet 353:416
    • (1999) Lancet , vol.353 , pp. 416
    • Raju, T.N.1
  • 117
    • 79959987811 scopus 로고    scopus 로고
    • Innervation patterns of autonomic axons in the human endocrine pancreas
    • Rodriguez-Diaz R, Abdulreda MH, Formoso AL et al (2011a) Innervation patterns of autonomic axons in the human endocrine pancreas. Cell Metab 14:45-54
    • (2011) Cell Metab , vol.14 , pp. 45-54
    • Rodriguez-Diaz, R.1    Abdulreda, M.H.2    Formoso, A.L.3
  • 118
    • 79960129197 scopus 로고    scopus 로고
    • Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans
    • Rodriguez-Diaz R, Dando R, Jacques-Silva MC et al (2011b) Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med 17:888-892
    • (2011) Nat Med , vol.17 , pp. 888-892
    • Rodriguez-Diaz, R.1    Dando, R.2    Jacques-Silva, M.C.3
  • 119
    • 84872800015 scopus 로고    scopus 로고
    • Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors
    • Ruiz de Azua I, Gautam D, Jain S et al (2012) Critical metabolic roles of beta-cell M3 muscarinic acetylcholine receptors. Life Sci 91:986-991
    • (2012) Life Sci , vol.91 , pp. 986-991
    • Ruiz De Azua, I.1    Gautam, D.2    Jain, S.3
  • 120
    • 79960740892 scopus 로고    scopus 로고
    • Galantamine alleviates inflammation and other obesity-associated complications in high-fat diet-fed mice
    • Satapathy SK, Ochani M, Dancho M et al (2011) Galantamine alleviates inflammation and other obesity-associated complications in high-fat diet-fed mice. Mol Med 17:599-606
    • (2011) Mol Med , vol.17 , pp. 599-606
    • Satapathy, S.K.1    Ochani, M.2    Dancho, M.3
  • 121
  • 122
    • 0031026681 scopus 로고    scopus 로고
    • Cholinergic transmission in pancreatic ganglia of the cat
    • Sha L, Love JA, Ma RC et al (1997) Cholinergic transmission in pancreatic ganglia of the cat. Pancreas 14:83-93 (Pubitemid 26427263)
    • (1997) Pancreas , vol.14 , Issue.1 , pp. 83-93
    • Sha, L.1    Love, J.A.2    Ma, R.C.3    Szurszewski, J.H.4
  • 123
    • 0036891170 scopus 로고    scopus 로고
    • Nicotinic receptor signaling in nonexcitable cells
    • DOI 10.1002/neu.10114
    • Sharma G, Vijayaraghavan S (2002) Nicotinic receptor signaling in nonexcitable cells. J Neurobiol 53:524-534 (Pubitemid 35375583)
    • (2002) Journal of Neurobiology , vol.53 , Issue.4 , pp. 524-534
    • Sharma, G.1    Vijayaraghavan, S.2
  • 124
    • 0027301754 scopus 로고
    • Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: Dose-dependency and desensitization
    • DOI 10.1210/en.133.1.11
    • Sharp BM, Matta SG (1993) Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: dose-dependency and desensitization. Endocrinology 133:11-19 (Pubitemid 23206368)
    • (1993) Endocrinology , vol.133 , Issue.1 , pp. 11-19
    • Sharp, B.M.1    Matta, S.G.2
  • 125
    • 57349197879 scopus 로고    scopus 로고
    • Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life
    • Somm E, Schwitzgebel VM, Vauthay DM et al (2008) Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life. Endocrinology 149:6289-6299
    • (2008) Endocrinology , vol.149 , pp. 6289-6299
    • Somm, E.1    Schwitzgebel, V.M.2    Vauthay, D.M.3
  • 126
    • 67349190864 scopus 로고    scopus 로고
    • Prenatal nicotine exposure and the programming of metabolic and cardiovascular disorders
    • Somm E, Schwitzgebel VM, Vauthay DM et al (2009) Prenatal nicotine exposure and the programming of metabolic and cardiovascular disorders. Mol Cell Endocrinol 304:69-77
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 69-77
    • Somm, E.1    Schwitzgebel, V.M.2    Vauthay, D.M.3
  • 127
    • 67349083986 scopus 로고    scopus 로고
    • Effect of maternal prenatal smoking on infant growth and development of obesity
    • Sowan NA, Stember ML (2000) Effect of maternal prenatal smoking on infant growth and development of obesity. J Perinat Educ 9:22-29
    • (2000) J Perinat Educ , vol.9 , pp. 22-29
    • Sowan, N.A.1    Stember, M.L.2
  • 128
    • 0022545770 scopus 로고
    • Modulation of insulin secretion by pancreatic ganglionic nicotinic receptors
    • Stagner JI, Samols E (1986) Modulation of insulin secretion by pancreatic ganglionic nicotinic receptors. Diabetes 35:849-854 (Pubitemid 16014434)
    • (1986) Diabetes , vol.35 , Issue.8 , pp. 849-854
    • Stagner, J.I.1    Samols, E.2
  • 129
    • 33846552537 scopus 로고    scopus 로고
    • Reduced nicotinic receptor function in sympathetic ganglia is responsible for the hypothermia in the acetylcholinesterase knockout mouse
    • DOI 10.1113/jphysiol.2006.120147
    • Sun M, Lee CJ, Shin HS (2007) Reduced nicotinic receptor function in sympathetic ganglia is responsible for the hypothermia in the acetylcholinesterase knockout mouse. J Physiol 578(Pt 3):751-764 (Pubitemid 46165507)
    • (2007) Journal of Physiology , vol.578 , Issue.3 , pp. 751-764
    • Sun, M.1    Lee, C.J.2    Shin, H.-S.3
  • 130
    • 0029911662 scopus 로고    scopus 로고
    • Alterations of lipolysis and lipoprotein lipase in chronically nicotine-treated rats
    • Sztalryd C, Hamilton J, Horwitz BA et al (1996) Alterations of lipolysis and lipoprotein lipase in chronically nicotine-treated rats. Am J Physiol 270(2 Pt 1):E215-E223
    • (1996) Am J Physiol , vol.270 , Issue.2 PART 1
    • Sztalryd, C.1    Hamilton, J.2    Horwitz, B.A.3
  • 131
    • 84860461624 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptors: A therapeutic target in the structure era
    • Taly A, Charon S (2012) Alpha7 nicotinic acetylcholine receptors: a therapeutic target in the structure era. Curr Drug Targets 13:695-706
    • (2012) Curr Drug Targets , vol.13 , pp. 695-706
    • Taly, A.1    Charon, S.2
  • 133
    • 0036907282 scopus 로고    scopus 로고
    • Overweight and obesity in 6- to 14-year-old Czech children in 1991: Protective effect of breast-feeding
    • DOI 10.1067/mpd.2002.128890
    • Toschke AM, Vignerova J, Lhotska L et al (2002b) Overweight and obesity in 6- to 14-year-old Czech children in 1991: protective effect of breast-feeding. J Pediatr 141:764-769 (Pubitemid 35471636)
    • (2002) Journal of Pediatrics , vol.141 , Issue.6 , pp. 764-769
    • Tosehke, A.M.1    Vignerova, J.2    Lhotska, L.3    Osancova, K.4    Koletzko, B.5    Von Kries, R.6
  • 134
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • Tracey KJ (2007) Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Investig 117:289-296
    • (2007) J Clin Investig , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 135
    • 13444271681 scopus 로고    scopus 로고
    • Refined structure of the nicotinic acetylcholine receptor at 4A resolution
    • Unwin N (2005) Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol 346:967-989
    • (2005) J Mol Biol , vol.346 , pp. 967-989
    • Unwin, N.1
  • 136
    • 84859914196 scopus 로고    scopus 로고
    • Alpha7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: The search for a Ca(2+) optimum
    • Uteshev VV (2012) Alpha7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimum. Adv Exp Med Biol 740:603-638
    • (2012) Adv Exp Med Biol , vol.740 , pp. 603-638
    • Uteshev, V.V.1
  • 139
    • 0024474491 scopus 로고
    • Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
    • Wada E, Wada K, Boulter J et al (1989) Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. J Comp Neurol 284:314-335 (Pubitemid 19185398)
    • (1989) Journal of Comparative Neurology , vol.284 , Issue.2 , pp. 314-335
    • Wada, E.1    Wada, K.2    Boulter, J.3    Deneris, E.4    Heinemann, S.5    Patrick, J.6    Swanson, L.W.7
  • 140
    • 0036939994 scopus 로고    scopus 로고
    • The role of neuronal nicotinic acetylcholine receptor subunits in autonomic ganglia: Lessons from knockout mice
    • DOI 10.1016/S0301-0082(02)00106-5, PII S0301008202001065
    • Wang N, Orr-Urtreger A, Korczyn AD (2002) The role of neuronal nicotinic acetylcholine receptor subunits in autonomic ganglia: lessons from knockout mice. Prog Neurobiol 68:341-360 (Pubitemid 36071511)
    • (2002) Progress in Neurobiology , vol.68 , Issue.5 , pp. 341-360
    • Wang, N.1    Orr-Urtreger, A.2    Korczyn, A.D.3
  • 142
    • 79951875569 scopus 로고    scopus 로고
    • Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance
    • Wang X, Yang Z, Xue B et al (2011) Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance. Endocrinology 152:836-846
    • (2011) Endocrinology , vol.152 , pp. 836-846
    • Wang, X.1    Yang, Z.2    Xue, B.3
  • 145
    • 0021227320 scopus 로고
    • Maternal adipose tissue response to nicotine administration in the pregnant rat: Effects on fetal body fat and cellularity
    • Williams CM, Kanagasabai T (1984) Maternal adipose tissue response to nicotine administration in the pregnant rat: effects on fetal body fat and cellularity. Br J Nutr 51:7-13 (Pubitemid 14063320)
    • (1984) British Journal of Nutrition , vol.51 , Issue.1 , pp. 7-13
    • Williams, C.M.1    Kanagasabai, T.2
  • 146
    • 0025358818 scopus 로고
    • Effects of nicotine on body weight, food consumption and body composition in male rats
    • DOI 10.1016/0024-3205(90)90425-Q
    • Winders SE, Grunberg NE (1990) Effects of nicotine on body weight, food consumption and body composition in male rats. Life Sci 46:1523-1530 (Pubitemid 20177954)
    • (1990) Life Sciences , vol.46 , Issue.21 , pp. 1523-1530
    • Winders, S.E.1    Grunberg, N.E.2
  • 147
    • 0016166156 scopus 로고
    • Neural control of the endocrine pancreas
    • Woods SC, Porte D Jr (1974) Neural control of the endocrine pancreas. Physiol Rev 54:596-619
    • (1974) Physiol Rev , vol.54 , pp. 596-619
    • Woods, S.C.1    Porte Jr., D.2
  • 149
    • 84871253591 scopus 로고    scopus 로고
    • Chronic exposure to nicotine enhances insulin sensitivity through alpha7 nicotinic acetylcholine receptor-STAT3 pathway
    • Xu TY, Guo LL, Wang P et al (2012) Chronic exposure to nicotine enhances insulin sensitivity through alpha7 nicotinic acetylcholine receptor-STAT3 pathway. PLoS ONE 7:e51217
    • (2012) PLoS ONE , vol.7
    • Xu, T.Y.1    Guo, L.L.2    Wang, P.3
  • 150
    • 0032835468 scopus 로고    scopus 로고
    • Infusion of nicotine into the LHA enhances dopamine and 5-HT release and suppresses food intake
    • DOI 10.1016/S0091-3057(99)00111-2, PII S0091305799001112
    • Yang ZJ, Blaha V, Meguid MM et al (1999) Infusion of nicotine into the LHA enhances dopamine and 5-HT release and suppresses food intake. Pharmacol Biochem Behav 64:155-159 (Pubitemid 29415808)
    • (1999) Pharmacology Biochemistry and Behavior , vol.64 , Issue.1 , pp. 155-159
    • Yang, Z.-J.1    Blaha, V.2    Meguid, M.M.3    Oler, A.4    Miyata, G.5
  • 151
    • 84863211864 scopus 로고    scopus 로고
    • A gene-family analysis of 61 genetic variants in the nicotinic acetylcholine receptor genes for insulin resistance and type 2 diabetes in American Indians
    • Yang J, Zhu Y, Cole SA et al (2012) A gene-family analysis of 61 genetic variants in the nicotinic acetylcholine receptor genes for insulin resistance and type 2 diabetes in American Indians. Diabetes 61:1888-1894
    • (2012) Diabetes , vol.61 , pp. 1888-1894
    • Yang, J.1    Zhu, Y.2    Cole, S.A.3
  • 152
    • 0025038827 scopus 로고
    • Effect of nicotine on norepinephrine turnover and thermogenesis in brown adipose tissue and metabolic rate in MSG obese mice
    • Yoshida T, Yoshioka K, Hiraoka N et al (1990) Effect of nicotine on norepinephrine turnover and thermogenesis in brown adipose tissue and metabolic rate in MSG obese mice. J Nutr Sci Vitaminol 36:123-130 (Pubitemid 20327503)
    • (1990) Journal of Nutritional Science and Vitaminology , vol.36 , Issue.2 , pp. 123-130
    • Yoshida, T.1    Yoshioka, K.2    Hiraoka, N.3    Kondo, M.4
  • 154
    • 12944302589 scopus 로고    scopus 로고
    • Evidence for functional nicotinic receptors on pancreatic beta cells
    • DOI 10.1016/j.metabol.2004.08.020, PII S0026049504003385
    • Yoshikawa H, Hellstrom-Lindahl E, Grill V (2005) Evidence for functional nicotinic receptors on pancreatic beta cells. Metabolism 54:247-254 (Pubitemid 40174855)
    • (2005) Metabolism: Clinical and Experimental , vol.54 , Issue.2 , pp. 247-254
    • Yoshikawa, H.1    Hellstrom-Lindahl, E.2    Grill, V.3
  • 155
    • 84868135296 scopus 로고    scopus 로고
    • Nicotinic regulation of energy homeostasis
    • Zoli M, Picciotto MR (2012) Nicotinic regulation of energy homeostasis. Nicotine Tob Res 14:1270-1290
    • (2012) Nicotine Tob Res , vol.14 , pp. 1270-1290
    • Zoli, M.1    Picciotto, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.