The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 1, 2004, Pages 52-58

  Liu, Run Hua ^a   Mizuta, Masanari ^a   Matsukura, Shigeru ^a,b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b Kishiwada City Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CYTOKINE; FATTY ACID; INSULIN; MESSENGER RNA; NICOTINE; NICOTINIC RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; INSULIN RESISTANCE; INSULIN SENSITIVITY; ISOTOPE LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADIPOCYTES; ADIPONECTIN; ANIMALS; ANTIBODIES; CELLS, CULTURED; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NICOTINE; PROTEIN SUBUNITS; PROTEINS; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRITIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3042548823     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.065037     Document Type: Article

References (40)

1. Albuquerque EX, Alkondon M, Pereira EF, Castro NG, Schrattenholz A, Barbosa CT, Bonfante-Cabarcas R, Aracava Y, Eisenberg HM, and Maelicke A (1997) Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function. J Pharmacol Exp Ther 280:1117-1136.
2. Bencherif M, Fowler K, Lukas RJ, and Lippiello PM (1995) Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain. J Pharmacol Exp Ther 275:987-994.
3. Buonanno A, Mudd J, and Merlie JP (1989) Isolation and characterization of the beta and epsilon subunit genes of mouse muscle acetylcholine receptor. J Biol Chem 264:7611-7616.
4. Didier M, Berman SA, Lindstrom J, and Bursztajn S (1995) Characterization of nicotinic acetylcholine receptors expressed in primary cultures of cerebellar granule cells. Brain Res Mol Brain Res 30:17-28.
5. Fasshauer M, Klein J, Neumann S, Eszlinger M, and Paschke R (2002) Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun 290:1084-1089.
6. Gotti C, Carbonnelle E, Moretti M, Zwart R, and Clementi F (2000) Drugs selective for nicotinic receptor subtypes: a real possibility or a dream? Behav Brain Res 113:183-192.
7. Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS, and Spiegelman BM (1994) Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. Endocrinology 134:264-270.
8. Hoss W, Lin JP, Matchett S, and Davies BD (1986) Characterization of noncholinergic nicotine receptors on human granulocytes. Biochem Pharmacol 35:2367-2372.
9. Hotamisligil SG, Shargill NS, and Spiegelman BM (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (Wash DC) 259:87-97.
10. Hu E, Liang P, and Spiegelman BM (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271:10697-10703.
11. Ke L, Eisenhour CM, Bencherif M, and Lukas RJ (1998) Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. I. Dose- and time-dependent effects of nicotine treatment. J Pharmacol Exp Ther 286:825-840.
12. Kern PA, Di Gregorio GB, Lu T, Rassouli N, and Ranganathan G (2003) Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance and tumor necrosis factor-alpha expression. Diabetes 52:1779-1785.
13. Kreier F, Fliers E, Voshol PJ, Van Eden CG, Havekes LM, Kalsbeek A, Van Heijningen CL, Sluiter AA, Mettenleiter TC, Romijn JA, et al. (2002) Selective parasympathetic innervation of subcutaneous and intra-abdominal fat-functional implications. J Clin Investig 110:1243-1250.
14. LaPolla RJ, Mayne KM, and Davidson N (1984) Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor. Proc Natl Acad Sci USA 81:7970-7974.
15. Lebargy F, Benhammou K, Morin D, Zini R, Urien S, Bree F, Bignon J, Branellee A, and Largue G (1996) Tobacco smoking induces expression of very-high-affinity nicotine binding sites on blood polymorphonuclear cells. Am J Respir Crit Care Med 153:1056-1063.
16. Lindstrom J, Anand R, Peng X, Gerzanich V, Wang F, and Li Y (1995) Neuronal nicotinic receptor subtypes. Ann NY Acad Sci 757:100-116.
17. Liu L, Chang GQ, Jiao YQ, and Simon SA (1998) Neuronal nicotinic acetylcholine receptors in rat trigeminal ganglia. Brain Res 800:238-245.
18. Liu RH, Kurose T, and Matsukura S (2001) Oral nicotine administration decreases tumor necrosis factor-alpha expression in fat tissues in obese rats. Metabolism 50: 79-85.
19. Liu RH, Mizuta M, and Matsukura S (2003) Long-term oral nicotine administration reduces insulin resistance in obese rats. Eur J Pharmacol 458:227-234.
20. Mabley JG, Pacher P, Southan GJ, Salzman AL, and Szabo C (2002) Nicotine reduces the incidence of type I diabetes in mice. J Pharmacol Exp Ther 300:876-881.
21. Madretsma GS, Donze GJ, van Dijk AP, Tak CJ, Wilson JH, and Zijlstra FJ (1996) Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells. Immunopharmacology 35:47-51.
22. Maeda N, Shimomura I, Kishida K, Nishizawa H, Matsuda M, Nagaretani H, Furuyama N, Kondo H, Takahashi M, Arita Y, et al. (2002) Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 8:731-737.
23. Marubio LM and Changeux J-P (2000) Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function. Eur J Pharmacol 393:113-121.
24. Maslinski W, Laskowska-Bozek H, and Ryzewski J (1992) Nicotinic receptors of rat lymphocytes during adjuvant polyarthritis. J Neurosci Res 31:336-340.
25. Matsuzawa Y, Funahashi T, and Nakamura T (1999) Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances. Ann NY Acad Sci 892:146-154.
26. Maus ADJ, Pereira EFR, Karachunski PI, Horton RM, Navaneetham D, Macklin KD, Cortes WS, Albuquerque EY, and Conti-Fine BM (1998) Human and rodent epithelial cells express functional nicotinic acetylcholine receptors. Mol Pharmacol 54:779-788.
27. Mohamed-Ali V, Pinkney JH, and Coppack SW (1998) Adipose tissue as an endocrine and paracrine organ. Int J Obes Relat Metab Disord 22:1145-1158.
28. Nguyen VT, Ndoye A, and Grando SA (2000) Novel human α9 acetylcholine receptor regulating keratinocyte adhesion is targeted by pemphigus vulgaris autoimmunity. Am J Pathol 157:1377-1391.
29. Rohwedel J, Horak V, Hebrok M, Fuchtbauer EM, and Wobus AM (1995) M-twist expression inhibits mouse embryonic stem cell-derived myogenic differentiation in vitro. Exp Cell Res 220:92-100.
30. Rubboli F, Court JA, Sala C, Morris C, Chini B, Perry E, and Clementi F (1994) Distribution of nicotinic receptors in the human hippocampus and thalamus. Eur J Neurosci 6:1596-1604.
31. Saito T, Ohnuki Y, Saeki Y, Nakagawa Y, Ishibashi K, Yanagisawa K, and Yamane A (2002) Postnatal changes in the nicotinic acetylcholine receptor subunits in rat masseter muscle. Arch Oral Biol 47:417-421.
32. Saltiel AR and Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature (Lond) 414:799-806.
33. Tassonyi E, Charpantier E, Muller D, Dumont L, and Bertrand D (2002) The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Res Bull 57:133-150.
34. Tseng J, Kwitek-Black AE, Erbe CB, Popper P, Jacob HJ, and Wackym PA (2001) Radiation hybrid mapping of 11 alpha and beta nicotinic acetylcholine receptor genes in Rattus norvegicus. Brain Res Mol Brain Res 91:169-173.
35. Ukkola O and Santaniemi M (2002) Adiponectin: a link between excess adiposity and associated comorbidities? J Mol Med 80:696-702.
36. Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, Li JH, Wang H, Yang H, Ulloa L, et al. (2003) Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature (Lond) 421:384-388.
37. Witzemann V, Stein E, Barg B, Konno T, Koenen M, Kues W, Criado M, Hofmann M, and Sakmann B (1990) Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle. Eur J Biochem 194:437-448.
38. Wonnacott S (1987) Brain nicotine binding sites. Hum Toxicol 6:343-353.
39. Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, et al. (2003) Globular adiponectin protected ob/ob mice from diabetes and apoE-deficient mice from atherosclerosis. J Biol Chem 278: 2461-2468.
40. Yoshida H, Sakagami H, Yamanaka Y, Amano Y, Yamaguchi M, Yamamura M, Fukuchi K, Gomi K, Ohata H, Momose K, et al. (1998) Induction of DNA fragmentation by nicotine in human myelogenous leukemic cell lines. Anticancer Res 18:2507-2511.