-
1
-
-
0011481429
-
The "ancient history" of bone
-
PMID:13982627
-
Romer AS. The "ancient history" of bone. Ann N Y Acad Sci 1963; 109:168-76; PMID:13982627; http://dx.doi.org/10.1111/j.1749-6632.1963.tb13466.x
-
(1963)
Ann N Y Acad Sci
, vol.109
, pp. 168-76
-
-
Romer, A.S.1
-
2
-
-
84855987634
-
The contribution of bone to whole-organism physiology
-
PMID:22258610
-
Karsenty G, Ferron M. The contribution of bone to whole-organism physiology. Nature 2012; 481:31420; PMID:22258610; http://dx.doi.org/10.1038/ nature10763
-
(2012)
Nature
, vol.481
, pp. 31420
-
-
Karsenty, G.1
Ferron, M.2
-
3
-
-
0038188450
-
Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases
-
Boyce BF, Xing L, Shakespeare W, Wang Y, Dalgarno D, Iuliucci J, Sawyer T. Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases. Kidney Int Suppl 2003; 85:S2-5; PMID:12753255; http://dx.doi.org/10.1046/j.1523-1755.63.s85.2.x (Pubitemid 36605852)
-
(2003)
Kidney International, Supplement
, vol.63
, Issue.85
-
-
Boyce, B.F.1
Xing, L.2
Shakespeare, W.3
Wang, Y.4
Dalgarno, D.5
Iuliucci, J.6
Sawyer, T.7
-
4
-
-
77954701060
-
Pathwaybased genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius bmd
-
PMID:20200951
-
Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, et al. Pathwaybased genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. J Bone Miner Res 2010; 25:1572-80; PMID:20200951; http://dx.doi.org/10.1002/jbmr.36
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1572-80
-
-
Zhang, L.1
Guo, Y.F.2
Liu, Y.Z.3
Liu, Y.J.4
Xiong, D.H.5
Liu, X.G.6
Wang, L.7
Yang, T.L.8
Lei, S.F.9
Guo, Y.10
-
5
-
-
80055083021
-
Sympathetic control of bone mass regulated by osteopontin
-
PMID:21990347
-
Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, et al. Sympathetic control of bone mass regulated by osteopontin. Proc Natl Acad Sci U S A 2011; 108:1776772; PMID:21990347; http://dx.doi.org/10.1073/pnas.1109402108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1776772
-
-
Nagao, M.1
Feinstein, T.N.2
Ezura, Y.3
Hayata, T.4
Notomi, T.5
Saita, Y.6
Hanyu, R.7
Hemmi, H.8
Izu, Y.9
Takeda, S.10
-
6
-
-
21344437987
-
BMP antagonists: Their roles in development and involvement in pathophysiology
-
DOI 10.1016/j.cytogfr.2005.02.007, PII S1359610105000407
-
Yanagita M. BMP antagonists: their roles in development and involvement in pathophysiology. Cytokine Growth Factor Rev 2005; 16:309-17; PMID:15951218; http://dx.doi.org/10.1016/j.cytogfr.2005.02.007 (Pubitemid 40910320)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.3 SPEC. ISS.
, pp. 309-317
-
-
Yanagita, M.1
-
7
-
-
84874113882
-
Noggin attenuates cerulein-induced acute pancreatitis and impaired autophagy
-
PMID:22850625
-
Cao Y, Yang W, Tyler MA, Gao X, Duan C, Kim SO, Aronson JF, Popov V, Takahashi H, Saito H, et al. Noggin attenuates cerulein-induced acute pancreatitis and impaired autophagy. Pancreas 2013; 42:3017; PMID:22850625; http://dx.doi.org/10.1097/MPA.0b013e31825b9f2c
-
(2013)
Pancreas
, vol.42
, pp. 3017
-
-
Cao, Y.1
Yang, W.2
Tyler, M.A.3
Gao, X.4
Duan, C.5
Kim, S.O.6
Aronson, J.F.7
Popov, V.8
Takahashi, H.9
Saito, H.10
-
8
-
-
77955172368
-
Autophagy negatively regulates wnt signalling by promoting dishevelled degradation
-
PMID:20639871
-
Gao C, Cao W, Bao L, Zuo W, Xie G, Cai T, Fu W, Zhang J, Wu W, Zhang X, et al. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol 2010; 12:78190; PMID:20639871; http://dx.doi.org/10. 1038/ncb2082
-
(2010)
Nat Cell Biol
, vol.20
, pp. 78190
-
-
Gao, C.1
Cao, W.2
Bao, L.3
Zuo, W.4
Xie, G.5
Cai, T.6
Fu, W.7
Zhang, J.8
Wu, W.9
Zhang, X.10
-
9
-
-
77957659422
-
Autophagic receptors nbr1 and p62 coregulate skeletal remodeling
-
PMID:20814249
-
Waters S, Marchbank K, Solomon E, Whitehouse CA. Autophagic receptors Nbr1 and p62 coregulate skeletal remodeling. Autophagy 2010; 6:9813; PMID:20814249; http://dx.doi.org/10.4161/auto.6.7.13155
-
(2010)
Autophagy
, vol.16
, pp. 9813
-
-
Waters, S.1
Marchbank, K.2
Solomon, E.3
Whitehouse, C.A.4
-
10
-
-
77955626805
-
Neighbor of brca1 gene (nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 mapk activity
-
PMID:20616007
-
Whitehouse CA, Waters S, Marchbank K, Horner A, McGowan NW, Jovanovic JV, Xavier GM, Kashima TG, Cobourne MT, Richards GO, et al. Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity. Proc Natl Acad Sci U S A 2010; 107:12913-8; PMID:20616007; http://dx.doi.org/10.1073/pnas.0913058107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12913-8
-
-
Whitehouse, C.A.1
Waters, S.2
Marchbank, K.3
Horner, A.4
McGowan, N.W.5
Jovanovic, J.V.6
Xavier, G.M.7
Kashima, T.G.8
Cobourne, M.T.9
Richards, G.O.10
-
11
-
-
78650918920
-
Foxo/4e-bp signaling in drosophila muscles regulates organismwide proteostasis during aging
-
PMID:21111239
-
Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organismwide proteostasis during aging. Cell 2010; 143:813-25; PMID:21111239; http://dx.doi.org/10.1016/j.cell.2010.10.007
-
(2010)
Cell
, vol.143
, pp. 813-25
-
-
Demontis, F.1
Perrimon, N.2
-
12
-
-
84881253436
-
Signalling pathways regulating muscle mass in ageing skeletal muscle
-
PMID:23686362
-
Sandri M, Barberi L, Bijlsma AY, Blaauw B, Dyar KA, Milan G, Mammucari C, Meskers CG, Pallafacchina G, Paoli A, et al. Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway. Biogerontology 2013; 14:303-23; PMID:23686362; http://dx.doi.org/10. 1007/s10522-013-9432-9
-
(2013)
The role of the IGF1-Akt-mTOR-FoxO pathway. Biogerontology
, vol.14
, pp. 303-23
-
-
Sandri, M.1
Barberi, L.2
Bijlsma, A.Y.3
Blaauw, B.4
Dyar, K.A.5
Milan, G.6
Mammucari, C.7
Meskers, C.G.8
Pallafacchina, G.9
Paoli, A.10
-
13
-
-
79960575561
-
Unraveling the role of foxos in bone-insights from mouse models
-
PMID:21664311
-
Almeida M. Unraveling the role of FoxOs in bone-insights from mouse models. Bone 2011; 49:31927; PMID:21664311; http://dx.doi.org/10.1016/j.bone. 2011.05.023
-
(2011)
Bone
, vol.49
, pp. 31927
-
-
Almeida, M.1
-
14
-
-
84879874726
-
Glucosamine activates autophagy in vitro and in vivo
-
PMID:23606170
-
Carames B, Kiosses WB, Akasaki Y, Brinson DC, Eap W, Koziol J, Lotz MK. Glucosamine activates autophagy in vitro and in vivo. Arthritis Rheum 2013; 65:1843-52; PMID:23606170; http://dx.doi.org/10.1002/art.37977
-
(2013)
Arthritis Rheum
, vol.65
, pp. 1843-52
-
-
Carames, B.1
Kiosses, W.B.2
Akasaki, Y.3
Brinson, D.C.4
Eap, W.5
Koziol, J.6
Lotz, M.K.7
-
15
-
-
8744224520
-
ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells
-
DOI 10.1074/jbc.M410010200
-
Yang X, Karsenty G. ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in nonosteoblastic cells. J Biol Chem 2004; 279:47109-14; PMID:15377660; http://dx.doi.org/10.1074/jbc. M410010200 (Pubitemid 39518367)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 47109-47114
-
-
Yang, X.1
Karsenty, G.2
-
16
-
-
33751412300
-
ATF4 mediation of NF1 functions in osteoblast revealsa nutritional basis for congenital skeletal dysplasiae
-
DOI 10.1016/j.cmet.2006.10.010, PII S1550413106003391
-
Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab 2006; 4:441-51; PMID:17141628; http://dx.doi.org/10.1016/j.cmet.2006.10.010 (Pubitemid 44817348)
-
(2006)
Cell Metabolism
, vol.4
, Issue.6
, pp. 441-451
-
-
Elefteriou, F.1
Benson, M.D.2
Sowa, H.3
Starbuck, M.4
Liu, X.5
Ron, D.6
Parada, LuisF.7
Karsenty, G.8
-
17
-
-
80051786264
-
Bone cell autophagy is regulated by environmental factors
-
PMID:21597271
-
Zahm AM, Bohensky J, Adams CS, Shapiro IM, Srinivas V. Bone cell autophagy is regulated by environmental factors. Cells Tissues Organs 2011; 194:274-8; PMID:21597271; http://dx.doi.org/10.1159/000324647
-
(2011)
Cells Tissues Organs
, vol.194
, pp. 274-8
-
-
Zahm, A.M.1
Bohensky, J.2
Adams, C.S.3
Shapiro, I.M.4
Srinivas, V.5
-
18
-
-
80053931553
-
Glucocorticoid dose determines osteocyte cell fate
-
PMID:21705669
-
Jia J, Yao W, Guan M, Dai W, Shahnazari M, Kar R, Bonewald L, Jiang JX, Lane NE. Glucocorticoid dose determines osteocyte cell fate. FASEB J 2011; 25:3366-76; PMID:21705669; http://dx.doi.org/10.1096/fj.11-182519
-
(2011)
FASEB J
, vol.25
, pp. 3366-76
-
-
Jia, J.1
Yao, W.2
Guan, M.3
Dai, W.4
Shahnazari, M.5
Kar, R.6
Bonewald, L.7
Jiang, J.X.8
Lane, N.E.9
-
19
-
-
78349253795
-
Glucocorticoid-induced autophagy in osteocytes
-
PMID:20564240
-
Xia X, Kar R, Gluhak-Heinrich J, Yao W, Lane NE, Bonewald LF, Biswas SK, Lo WK, Jiang JX. Glucocorticoid-induced autophagy in osteocytes. J Bone Miner Res 2010; 25:2479-88; PMID:20564240; http://dx.doi.org/10.1002/jbmr.160
-
(2010)
J Bone Miner Res
, vol.25
, pp. 2479-88
-
-
Xia, X.1
Kar, R.2
Gluhak-Heinrich, J.3
Yao, W.4
Lane, N.E.5
Bonewald, L.F.6
Biswas, S.K.7
Lo, W.K.8
Jiang, J.X.9
-
20
-
-
83755225707
-
The osteoclast and its unique cytoskeleton
-
PMID:22172034
-
Teitelbaum SL. The osteoclast and its unique cytoskeleton. Ann N Y Acad Sci 2011; 1240:14-7; PMID:22172034; http://dx.doi.org/10.1111/j.1749-6632.2011. 06283.x
-
(2011)
Ann N Y Acad Sci
, vol.1240
, pp. 14-7
-
-
Teitelbaum, S.L.1
-
21
-
-
34447538519
-
Osteoclast differentiation and gene regulation
-
PMID:17127260
-
Zhao Q, Shao J, Chen W, Li YP. Osteoclast differentiation and gene regulation. Front Biosci 2007; 12:2519-29; PMID:17127260; http://dx.doi.org/10. 2741/2252
-
(2007)
Front Biosci
, vol.20
, pp. 2519-29
-
-
Zhao, Q.1
Shao, J.2
Chen, W.3
Li, Y.P.4
-
22
-
-
84865956047
-
Fusion and fission" unveils remarkable insights into osteoclast plasticity
-
author reply 159; PMID:22752618
-
Pavlos NJ, Ng PY. "Fusion and fission" unveils remarkable insights into osteoclast plasticity. Calcif Tissue Int 2012; 91:157-8, author reply 159; PMID:22752618; http://dx.doi.org/10.1007/s00223-012-9620-7
-
(2012)
Calcif Tissue Int
, vol.91
, pp. 157-8
-
-
Pavlos, N.J.1
Ng, P.Y.2
-
23
-
-
58549115903
-
Regulation of bone formation by osteoclasts involves wnt/bmp signaling and the chemokine sphingosine-1-phosphate
-
PMID:19075223
-
Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ. Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci U S A 2008; 105:20764-9; PMID:19075223; http://dx.doi.org/10.1073/pnas.0805133106
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20764-9
-
-
Pederson, L.1
Ruan, M.2
Westendorf, J.J.3
Khosla, S.4
Oursler, M.J.5
-
24
-
-
84868549658
-
Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis
-
PMID:22691949
-
Ishii M, Kikuta J. Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis. Biochim Biophys Acta 2013; 1831:223-7; PMID:22691949; http://dx.doi.org/10.1016/j.bbalip.2012.06.002
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 223-7
-
-
Ishii, M.1
Kikuta, J.2
-
25
-
-
84864823667
-
Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans
-
PMID:22679064
-
Lee SH, Lee SY, Lee YS, Kim BJ, Lim KH, Cho EH, Kim SW, Koh JM, Kim GS. Higher circulating sphingosine 1-phosphate levels are associated with lower bone mineral density and higher bone resorption marker in humans. J Clin Endocrinol Metab 2012; 97:E1421-8; PMID:22679064; http://dx.doi.org/10.1210/jc.2012-1044
-
(2012)
J Clin Endocrinol Meta
, vol.97
-
-
Lee, S.H.1
Lee, S.Y.2
Lee, Y.S.3
Kim, B.J.4
Lim, K.H.5
Cho, E.H.6
Kim, S.W.7
Koh, J.M.8
Kim, G.S.9
-
26
-
-
0037608771
-
Hypoxia is a major stimulator of osteoclast formation and bone resorption
-
DOI 10.1002/jcp.10321
-
Arnett TR, Gibbons DC, Utting JC, Orriss IR, Hoebertz A, Rosendaal M, Meghji S. Hypoxia is a major stimulator of osteoclast formation and bone resorption. J Cell Physiol 2003; 196:2-8; PMID:12767036; http://dx.doi.org/10. 1002/jcp.10321 (Pubitemid 36676438)
-
(2003)
Journal of Cellular Physiology
, vol.196
, Issue.1
, pp. 2-8
-
-
Arnett, T.R.1
Gibbons, D.C.2
Utting, J.C.3
Orriss, I.R.4
Hoebertz, A.5
Rosendaal, M.6
Meghji, S.7
-
27
-
-
80052589570
-
Autophagy regulates hypoxia-induced osteoclastogenesis through the hif-1a/bnip3 signaling pathway
-
PMID:21465467
-
Zhao Y, Chen G, Zhang W, Xu N, Zhu JY, Jia J, Sun ZJ, Wang YN, Zhao YF. Autophagy regulates hypoxia-induced osteoclastogenesis through the HIF-1a/BNIP3 signaling pathway. J Cell Physiol 2012; 227:639-48; PMID:21465467; http://dx.doi.org/10.1002/jcp.22768
-
(2012)
J Cell Physiol
, vol.227
, pp. 639-48
-
-
Zhao, Y.1
Chen, G.2
Zhang, W.3
Xu, N.4
Zhu, J.Y.5
Jia, J.6
Sun, Z.J.7
Wang, Y.N.8
Zhao, Y.F.9
-
28
-
-
83455173649
-
Autophagy proteins regulate the secretory component of osteoclastic bone resorption
-
PMID:22055344
-
DeSelm CJ, Miller BC, Zou W, Beatty WL, van Meel E, Takahata Y, Klumperman J, Tooze SA, Teitelbaum SL, Virgin HW. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell 2011; 21:966-74; PMID:22055344; http://dx.doi.org/10.1016/j.devcel.2011.08.016
-
(2011)
Dev Cell
, vol.21
, pp. 966-74
-
-
DeSelm, C.J.1
Miller, B.C.2
Zou, W.3
Beatty, W.L.4
Van Meel, E.5
Takahata, Y.6
Klumperman, J.7
Tooze, S.A.8
Teitelbaum, S.L.9
Virgin, H.W.10
-
29
-
-
84860307467
-
Microtubule-associated protein light chain 3 regulates cdc42-dependent actin ring formation in osteoclast
-
PMID:22465708
-
Chung YH, Yoon SY, Choi B, Sohn DH, Yoon KH, Kim WJ, Kim DH, Chang EJ. Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in osteoclast. Int J Biochem Cell Biol 2012; 44:989-97; PMID:22465708; http://dx.doi.org/10.1016/j.biocel.2012.03.007
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 989-97
-
-
Chung, Y.H.1
Yoon, S.Y.2
Choi, B.3
Sohn, D.H.4
Yoon, K.H.5
Kim, W.J.6
Kim, D.H.7
Chang, E.J.8
-
30
-
-
33746805387
-
Signaling, polyubiquitination, trafficking, and inclusions: Sequestosome 1/p62's role in neurodegenerative disease
-
PMID:17047309
-
Wooten MW, Hu X, Babu JR, Seibenhener ML, Geetha T, Paine MG, Wooten MC. Signaling, polyubiquitination, trafficking, and inclusions: sequestosome 1/p62's role in neurodegenerative disease. J Biomed Biotechnol 2006; 2006:62079; PMID:17047309; http://dx.doi.org/10.1155/JBB/2006/62079
-
(2006)
J Biomed Biotechnol
, vol.2006
, pp. 62079
-
-
Wooten, M.W.1
Hu, X.2
Babu, J.R.3
Seibenhener, M.L.4
Geetha, T.5
Paine, M.G.6
Wooten, M.C.7
-
31
-
-
84871000478
-
The role of alfy in selective autophagy
-
PMID:22653340
-
Isakson P, Holland P, Simonsen A. The role of ALFY in selective autophagy. Cell Death Differ 2013; 20:12-20; PMID:22653340; http://dx.doi.org/ 10.1038/cdd.2012.66
-
(2013)
Cell Death Differ
, vol.20
, pp. 12-20
-
-
Isakson, P.1
Holland, P.2
Simonsen, A.3
-
32
-
-
78549251353
-
Functional interaction between sequestosome-1/p62 and autophagy-linked fyvecontaining protein wdfy3 in human osteoclasts
-
PMID:20971078
-
Hocking LJ, Mellis DJ, McCabe PS, Helfrich MH, Rogers MJ. Functional interaction between sequestosome-1/p62 and autophagy-linked FYVEcontaining protein WDFY3 in human osteoclasts. Biochem Biophys Res Commun 2010; 402:5438; PMID:20971078; http://dx.doi.org/10.1016/j.bbrc.2010.10.076
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 5438
-
-
Hocking, L.J.1
Mellis, D.J.2
McCabe, P.S.3
Helfrich, M.H.4
Rogers, M.J.5
-
33
-
-
77950903972
-
The selective macroautophagic degradation of aggregated proteins requires the pi3p-binding protein alfy
-
PMID:20417604
-
Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, et al. The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy. Mol Cell 2010; 38:26579; PMID:20417604; http://dx.doi.org/10.1016/ j.molcel.2010.04.007
-
(2010)
Mol Cell
, vol.38
, pp. 26579
-
-
Filimonenko, M.1
Isakson, P.2
Finley, K.D.3
Anderson, M.4
Jeong, H.5
Melia, T.J.6
Bartlett, B.J.7
Myers, K.M.8
Birkeland, H.C.9
Lamark, T.10
-
34
-
-
84859423325
-
Paget's disease of bone: Evidence for complex pathogenetic interactions
-
PMID:21959292
-
Chung PY, Van Hul W. Paget's disease of bone: evidence for complex pathogenetic interactions. Semin Arthritis Rheum 2012; 41:619-41; PMID:21959292; http://dx.doi.org/10.1016/j.semarthrit.2011.07.005
-
(2012)
Semin Arthritis Rheum
, vol.41
, pp. 619-41
-
-
Chung, P.Y.1
Van Hul, W.2
-
35
-
-
84866001357
-
Pathogenesis of paget disease of bone
-
PMID:22543925
-
Ralston SH, Layfield R. Pathogenesis of Paget disease of bone. Calcif Tissue Int 2012; 91:97-113; PMID:22543925; http://dx.doi.org/10.1007/s00223-012- 9599-0
-
(2012)
Calcif Tissue Int
, vol.91
, pp. 97-113
-
-
Ralston, S.H.1
Layfield, R.2
-
36
-
-
70349764552
-
The p62 p392l mutation linked to paget's disease induces activation of human osteoclasts
-
PMID:19589897
-
Chamoux E, Couture J, Bisson M, Morissette J, Brown JP, Roux S. The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts. Mol Endocrinol 2009; 23:1668-80; PMID:19589897; http://dx.doi.org/10.1210/me.2009-0066
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1668-80
-
-
Chamoux, E.1
Couture, J.2
Bisson, M.3
Morissette, J.4
Brown, J.P.5
Roux, S.6
-
37
-
-
0018774333
-
Billiard-player's fingers: An unusual case of Paget's disease of bone
-
Solomon LR. Billiard-player's fingers: an unusual case of Paget's disease of bone. Br Med J 1979; 1:931; PMID:435885; http://dx.doi.org/10.1136/bmj.1. 6168.931 (Pubitemid 9148199)
-
(1979)
British Medical Journal
, vol.1
, Issue.6168
, pp. 931
-
-
Solomon, L.R.1
-
38
-
-
0036755763
-
Paget's disease of bone in lancashire and arsenic pesticide in cotton mill wastewater: A speculative hypothesis
-
PMID:12231419
-
Lever JH. Paget's disease of bone in Lancashire and arsenic pesticide in cotton mill wastewater: a speculative hypothesis. Bone 2002; 31:4346; PMID:12231419; http://dx.doi.org/10.1016/S8756-3282(02)00833-5
-
(2002)
Bone
, vol.31
, pp. 4346
-
-
Lever, J.H.1
-
39
-
-
84863219886
-
Epidemiogenetic study of french families with paget's disease of bone
-
PMID:21962384
-
Michou L, Collet C, Morissette J, Audran M, Thomas T, Gagnon E, Launay JM, Laplanche JL, Brown JP, Orcel P. Epidemiogenetic study of French families with Paget's disease of bone. Joint Bone Spine 2012; 79:393-8; PMID:21962384; http://dx.doi.org/10.1016/j.jbspin.2011.07.005
-
(2012)
Joint Bone Spine
, vol.79
, pp. 393-8
-
-
Michou, L.1
Collet, C.2
Morissette, J.3
Audran, M.4
Thomas, T.5
Gagnon, E.6
Launay, J.M.7
Laplanche, J.L.8
Brown, J.P.9
Orcel, P.10
-
40
-
-
77950664208
-
Insights into the pathogenesis of paget's disease
-
PMID:20392234
-
Roodman GD. Insights into the pathogenesis of Paget's disease. Ann N Y Acad Sci 2010; 1192:176-80; PMID:20392234; http://dx.doi.org/10.1111/j.1749- 6632.2009.05214.x
-
(2010)
Ann N Y Acad Sci
, vol.1192
, pp. 176-80
-
-
Roodman, G.D.1
-
41
-
-
0028914326
-
Frequency and characteristics of familial aggregation of paget's disease of bone
-
PMID:7610939
-
Morales-Piga AA, Rey-Rey JS, Corres-González J, García-Sagredo JM, López-Abente G. Frequency and characteristics of familial aggregation of Paget's disease of bone. J Bone Miner Res 1995; 10:66370; PMID:7610939; http://dx.doi.org/10.1002/jbmr.5650100421
-
(1995)
J Bone Miner Res
, vol.10
, pp. 66370
-
-
Morales-Piga, A.A.1
Rey-Rey, J.S.2
Corres-González, J.3
García-Sagredo, J.M.4
López-Abente, G.5
-
42
-
-
0037108914
-
Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's diease
-
Hocking LJ, Lucas GJ, Daroszewska A, Mangion J, Olavesen M, Cundy T, Nicholson GC, Ward L, Bennett ST, Wuyts W, et al. Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease. Hum Mol Genet 2002; 11:2735-9; PMID:12374763; http://dx.doi.org/10.1093/hmg/11.22.2735 (Pubitemid 35214900)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.22
, pp. 2735-2739
-
-
Hocking, L.J.1
Lucas, G.J.A.2
Daroszewska, A.3
Mangion, J.4
Olavesen, M.5
Cundy, T.6
Nicholson, G.C.7
Ward, L.8
Bennett, S.T.9
Wuyts, W.10
Van Hul, W.11
Ralston, S.H.12
-
43
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy[S]
-
DOI 10.1074/jbc.M702824200
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45; PMID:17580304; http://dx.doi.org/10.1074/jbc. M702824200 (Pubitemid 47328003)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.33
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.-A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
44
-
-
77952914565
-
P62/sqstm1 and alfy interact to facilitate the formation of p62 bodies/alis and their degradation by autophagy
-
PMID:20168092
-
Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Overvatn A, Stenmark H, Bjorkoy G, Simonsen A, et al. p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy. Autophagy 2010; 6:330-44; PMID:20168092; http://dx.doi.org/10.4161/auto.6.3. 11226
-
(2010)
Autophagy
, vol.16
, pp. 330-44
-
-
Clausen, T.H.1
Lamark, T.2
Isakson, P.3
Finley, K.4
Larsen, K.B.5
Brech, A.6
Overvatn, A.7
Stenmark, H.8
Bjorkoy, G.9
Simonsen, A.10
-
45
-
-
77952781968
-
Physical and functional interaction of sequestosome 1 with keap1 regulates the keap1-nrf2 cell defense pathway
-
PMID:20378532
-
Copple IM, Lister A, Obeng AD, Kitteringham NR, Jenkins RE, Layfield R, Foster BJ, Goldring CE, Park BK. Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway. J Biol Chem 2010; 285:16782-8; PMID:20378532; http://dx.doi.org/10.1074/jbc. M109.096545
-
(2010)
J Biol Chem
, vol.285
, pp. 16782-8
-
-
Copple, I.M.1
Lister, A.2
Obeng, A.D.3
Kitteringham, N.R.4
Jenkins, R.E.5
Layfield, R.6
Foster, B.J.7
Goldring, C.E.8
Park, B.K.9
-
46
-
-
84865287281
-
Keap1 degradation by autophagy for the maintenance of redox homeostasis
-
PMID:22872865
-
Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, Yamamoto M. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc Natl Acad Sci U S A 2012; 109:13561-6; PMID:22872865; http://dx.doi.org/10.1073/pnas.1121572109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13561-6
-
-
Taguchi, K.1
Fujikawa, N.2
Komatsu, M.3
Ishii, T.4
Unno, M.5
Akaike, T.6
Motohashi, H.7
Yamamoto, M.8
-
47
-
-
33745871571
-
Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation
-
DOI 10.1074/jbc.M600603200
-
Hinoi E, Fujimori S, Wang L, Hojo H, Uno K, Yoneda Y. Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation. J Biol Chem 2006; 281:18015-24; PMID:16613847; http://dx.doi.org/10.1074/jbc. M600603200 (Pubitemid 44035601)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.26
, pp. 18015-18024
-
-
Hinoi, E.1
Fujimori, S.2
Wang, L.3
Hojo, H.4
Uno, K.5
Yoneda, Y.6
-
48
-
-
77955653742
-
Suppression of nf-kappab signaling by keap1 regulation of ikkbeta activity through autophagic degradation and inhibition of phosphorylation
-
PMID:20600852
-
Kim JE, You DJ, Lee C, Ahn C, Seong JY, Hwang JI. Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation. Cell Signal 2010; 22:1645-54; PMID:20600852; http://dx.doi.org/10.1016/j.cellsig.2010.06.004
-
(2010)
Cell Signal
, vol.22
, pp. 1645-54
-
-
Kim, J.E.1
You, D.J.2
Lee, C.3
Ahn, C.4
Seong, J.Y.5
Hwang, J.I.6
-
49
-
-
80053586265
-
P62 is a key regulator of nutrient sensing in the mtorc1 pathway
-
PMID:21981924
-
Duran A, Amanchy R, Linares JF, Joshi J, AbuBaker S, Porollo A, Hansen M, Moscat J, Diaz-Meco MT. p62 is a key regulator of nutrient sensing in the mTORC1 pathway. Mol Cell 2011; 44:13446; PMID:21981924; http://dx.doi.org/10. 1016/j.molcel.2011.06.038
-
(2011)
Mol Cell
, vol.44
, pp. 13446
-
-
Duran, A.1
Amanchy, R.2
Linares, J.F.3
Joshi, J.4
AbuBaker, S.5
Porollo, A.6
Hansen, M.7
Moscat, J.8
Diaz-Meco, M.T.9
-
50
-
-
82455172117
-
Serine 403 phosphorylation of p62/sqstm1 regulates selective autophagic clearance of ubiquitinated proteins
-
PMID:22017874
-
Matsumoto G, Wada K, Okuno M, Kurosawa M, Nukina N. Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Mol Cell 2011; 44:27989; PMID:22017874; http://dx.doi.org/10.1016/j.molcel.2011.07.039
-
(2011)
Mol Cell
, vol.44
, pp. 27989
-
-
Matsumoto, G.1
Wada, K.2
Okuno, M.3
Kurosawa, M.4
Nukina, N.5
-
51
-
-
15344339092
-
Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations
-
DOI 10.1359/JBMR.041205
-
Cavey JR, Ralston SH, Hocking LJ, Sheppard PW, Ciani B, Searle MS, Layfield R. Loss of ubiquitinbinding associated with Paget's disease of bone p62 (SQSTM1) mutations. J Bone Miner Res 2005; 20:619-24; PMID:15765181; http://dx.doi.org/10.1359/JBMR.041205 (Pubitemid 40393070)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.4
, pp. 619-624
-
-
Cavey, J.R.1
Ralston, S.H.2
Hocking, L.J.3
Sheppard, P.W.4
Ciani, B.5
Searle, M.S.6
Layfield, R.7
-
52
-
-
33646597289
-
Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone
-
DOI 10.1007/s00223-005-1299-6
-
Cavey JR, Ralston SH, Sheppard PW, Ciani B, Gallagher TR, Long JE, Searle MS, Layfield R. Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone. Calcif Tissue Int 2006; 78:271-7; PMID:16691492; http://dx.doi.org/10.1007/s00223-005-1299-6 (Pubitemid 43725186)
-
(2006)
Calcified Tissue International
, vol.78
, Issue.5
, pp. 271-277
-
-
Cavey, J.R.1
Ralston, S.H.2
Sheppard, P.W.3
Ciani, B.4
Gallagher, T.R.A.5
Long, J.E.6
Searle, M.S.7
Layfield, R.8
-
53
-
-
65549140668
-
Characterization of a non-uba domain missense mutation of sequestosome 1 (sqstm1) in paget's disease of bone
-
PMID:19049332
-
Najat D, Garner T, Hagen T, Shaw B, Sheppard PW, Falchetti A, Marini F, Brandi ML, Long JE, Cavey JR, et al. Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone. J Bone Miner Res 2009; 24:632-42; PMID:19049332; http://dx.doi.org/10.1359/jbmr.081204
-
(2009)
J Bone Miner Res
, vol.24
, pp. 632-42
-
-
Najat, D.1
Garner, T.2
Hagen, T.3
Shaw, B.4
Sheppard, P.W.5
Falchetti, A.6
Marini, F.7
Brandi, M.L.8
Long, J.E.9
Cavey, J.R.10
-
54
-
-
70349101680
-
Sequestosome 1 mutations in paget's disease of bone in australia: Prevalence, genotype/phenotype correlation, and a novel non-uba domain mutation (p364s) associated with increased nf-kappab signaling without loss of ubiquitin binding
-
PMID:19257822
-
Rea SL, Walsh JP, Ward L, Magno AL, Ward BK, Shaw B, Layfield R, Kent GN, Xu J, Ratajczak T. Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding. J Bone Miner Res 2009; 24:1216-23; PMID:19257822; http://dx.doi.org/10.1359/jbmr.090214
-
(2009)
J Bone Miner Res
, vol.24
, pp. 1216-23
-
-
Rea, S.L.1
Walsh, J.P.2
Ward, L.3
Magno, A.L.4
Ward, B.K.5
Shaw, B.6
Layfield, R.7
Kent, G.N.8
Xu, J.9
Ratajczak, T.10
-
55
-
-
84862495658
-
Autophagy: A new player in skeletal maintenance?
-
PMID:22706899
-
Hocking LJ, Whitehouse C, Helfrich MH. Autophagy: a new player in skeletal maintenance? J Bone Miner Res 2012; 27:1439-47; PMID:22706899; http://dx.doi.org/10.1002/jbmr.1668
-
(2012)
J Bone Miner Res
, vol.27
, pp. 1439-47
-
-
Hocking, L.J.1
Whitehouse, C.2
Helfrich, M.H.3
-
56
-
-
77953858790
-
Traf6 and a20 regulate lysine 63-linked ubiquitination of beclin-1 to control tlr4-induced autophagy
-
PMID:20501938
-
Shi CS, Kehrl JH. TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci Signal 2010; 3:ra42; PMID:20501938; http://dx.doi.org/10.1126/scisignal.2000751
-
(2010)
Sci Signal
, vol.3
-
-
Shi, C.S.1
Kehrl, J.H.2
-
57
-
-
84857657829
-
Regulation of toll-like receptor signaling by ndp52-mediated selective autophagy is normally inactivated by a20
-
PMID:21964925
-
Inomata M, Niida S, Shibata K, Into T. Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20. Cell Mol Life Sci 2012; 69:963-79; PMID:21964925; http://dx.doi.org/10.1007/ s00018-011-0819-y
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 963-79
-
-
Inomata, M.1
Niida, S.2
Shibata, K.3
Into, T.4
-
58
-
-
76349090912
-
The ikk complex contributes to the induction of autophagy
-
PMID:19959994
-
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, et al. The IKK complex contributes to the induction of autophagy. EMBO J 2010; 29:61931; PMID:19959994; http://dx.doi.org/10.1038/emboj.2009.364
-
(2010)
EMBO J
, vol.29
, pp. 61931
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
Kepp, O.7
Tasdemir, E.8
Galluzzi, L.9
Shen, S.10
-
59
-
-
79959536377
-
Autophagosomal ikappab alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappab (nf-kappab) activity
-
PMID:21454695
-
Colleran A, Ryan A, O'Gorman A, Mureau C, Liptrot C, Dockery P, Fearnhead H, Egan LJ. Autophagosomal IkappaB alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappaB (NF-kappaB) activity. J Biol Chem 2011; 286:2288693; PMID:21454695; http://dx.doi.org/10.1074/jbc. M110.199950
-
(2011)
J Biol Chem
, vol.286
, pp. 2288693
-
-
Colleran, A.1
Ryan, A.2
O'Gorman, A.3
Mureau, C.4
Liptrot, C.5
Dockery, P.6
Fearnhead, H.7
Egan, L.J.8
-
60
-
-
83555168258
-
Inhibition of autophagy by tab2 and tab3
-
PMID:22081109
-
Criollo A, Niso-Santano M, Malik SA, Michaud M, Morselli E, Marino G, Lachkar S, Arkhipenko AV, Harper F, Pierron G, et al. Inhibition of autophagy by TAB2 and TAB3. EMBO J 2011; 30:490820; PMID:22081109; http://dx.doi.org/10. 1038/emboj.2011.413
-
(2011)
EMBO J
, vol.30
, pp. 490820
-
-
Criollo, A.1
Niso-Santano, M.2
Malik, S.A.3
Michaud, M.4
Morselli, E.5
Marino, G.6
Lachkar, S.7
Arkhipenko, A.V.8
Harper, F.9
Pierron, G.10
-
61
-
-
84857305639
-
Direct molecular interactions between beclin 1 and the canonical nfb activation pathway
-
PMID:22301997
-
Niso-Santano M, Criollo A, Malik SA, Michaud M, Morselli E, Mari?o G, Lachkar S, Galluzzi L, Maiuri MC, Kroemer G. Direct molecular interactions between Beclin 1 and the canonical NF?B activation pathway. Autophagy 2012; 8:268-70; PMID:22301997; http://dx.doi.org/10.4161/auto.8.2.18845
-
(2012)
Autophagy
, vol.8
, pp. 268-70
-
-
Niso-Santano, M.1
Criollo, A.2
Malik, S.A.3
Michaud, M.4
Morselli, E.5
Marino, G.6
Lachkar, S.7
Galluzzi, L.8
Maiuri, M.C.9
Kroemer, G.10
-
62
-
-
84864928990
-
Context-dependent regulation of autophagy by ikk-nf-kappab signaling: Impact on the aging process
-
PMID:22899934
-
Salminen A, Hyttinen JM, Kauppinen A, Kaarniranta K. Context-dependent regulation of autophagy by IKK-NF-kappaB signaling: impact on the aging process. Int J Cell Biol 2012; 2012:849541; PMID:22899934; http://dx.doi.org/10.1155/ 2012/849541
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 849541
-
-
Salminen, A.1
Hyttinen, J.M.2
Kauppinen, A.3
Kaarniranta, K.4
-
63
-
-
0036094026
-
Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in paget disease of bone
-
DOI 10.1086/340731
-
Laurin N, Brown JP, Morissette J, Raymond V. Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Am J Hum Genet 2002; 70:1582-8; PMID:11992264; http://dx.doi.org/10.1086/340731 (Pubitemid 34533906)
-
(2002)
American Journal of Human Genetics
, vol.70
, Issue.6
, pp. 1582-1588
-
-
Laurin, N.1
Brown, J.P.2
Morissette, J.3
Raymond, V.4
-
64
-
-
58149280230
-
Genepage project. Genetic epidemiology of paget's disease of bone in italy: Sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial italian cases of paget's disease of bone
-
PMID:19067022
-
Falchetti A, Di Stefano M, Marini F, Ortolani S, Ulivieri MF, Bergui S, Masi L, Cepollaro C, Benucci M, Di Munno O, et al.; GenePage Project. Genetic epidemiology of Paget's disease of bone in italy: sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget's disease of bone. Calcif Tissue Int 2009; 84:2037; PMID:19067022; http://dx.doi.org/10.1007/s00223-008-9192-8
-
(2009)
Calcif Tissue Int
, vol.84
, pp. 2037
-
-
Falchetti, A.1
Di Stefano, M.2
Marini, F.3
Ortolani, S.4
Ulivieri, M.F.5
Bergui, S.6
Masi, L.7
Cepollaro, C.8
Benucci, M.9
Di Munno, O.10
-
65
-
-
79751527853
-
Novel sqstm1 mutations in patients with paget's disease of bone in an unrelated multiethnic american population
-
PMID:21073987
-
Michou L, Morissette J, Gagnon ER, Marquis A, Dellabadia M, Brown JP, Siris ES. Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population. Bone 2011; 48:456-60; PMID:21073987; http://dx.doi.org/10.1016/j.bone.2010.11.004
-
(2011)
Bone
, vol.48
, pp. 456-60
-
-
Michou, L.1
Morissette, J.2
Gagnon, E.R.3
Marquis, A.4
Dellabadia, M.5
Brown, J.P.6
Siris, E.S.7
-
66
-
-
33846479861
-
Paget's disease of bone in the French population: Novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations
-
DOI 10.1359/jbmr.061106
-
Collet C, Michou L, Audran M, Chasseigneaux S, Hilliquin P, Bardin T, Lemaire I, Cornelis F, Launay JM, Orcel P, et al. Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations. J Bone Miner Res 2007; 22:310-7; PMID:17129171; http://dx.doi.org/10.1359/jbmr.061106 (Pubitemid 46167801)
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.2
, pp. 310-317
-
-
Collet, C.1
Michou, L.2
Audran, M.3
Chasseigneaux, S.4
Hilliquin, P.5
Bardin, T.6
Lemaire, I.7
Cornelis, F.8
Launay, J.-M.9
Orcel, P.10
Laplanche, J.-L.11
-
67
-
-
79959810997
-
A point mutation in the ubiquitin-associated domain of sqsmt1 is sufficient to cause a paget's disease-like disorder in mice
-
PMID:21515589
-
Daroszewska A, van 't Hof RJ, Rojas JA, Layfield R, Landao-Basonga E, Rose L, Rose K, Ralston SH. A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice. Hum Mol Genet 2011; 20:2734-44; PMID:21515589; http://dx.doi.org/10.1093/hmg/ddr172
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2734-44
-
-
Daroszewska, A.1
Van 't Hof, R.J.2
Rojas, J.A.3
Layfield, R.4
Landao-Basonga, E.5
Rose, L.6
Rose, K.7
Ralston, S.H.8
-
68
-
-
84862499477
-
Paget's diseasecausing mutations in sequestosome-1 impair autophagic protein degradation
-
Abstr 1081
-
Azzam E, Helfrich MH, Hocking LJ. Paget's diseasecausing mutations in Sequestosome-1 impair autophagic protein degradation. J Bone Miner Res 2011; 26:Abstr 1081
-
(2011)
J Bone Miner Res
, vol.26
-
-
Azzam, E.1
Helfrich, M.H.2
Hocking, L.J.3
-
69
-
-
84855860820
-
Ubqln2/p62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia
-
PMID:22246868
-
Fecto F, Siddique T. UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia. Muscle Nerve 2012; 45:15762; PMID:22246868; http://dx.doi.org/10.1002/mus.23278
-
(2012)
Muscle Nerve
, vol.45
, pp. 15762
-
-
Fecto, F.1
Siddique, T.2
-
70
-
-
84867543551
-
Sqstm1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
TODEM Study Group PMID:22972638
-
Rubino E, Rainero I, Chió A, Rogaeva E, Galimberti D, Fenoglio P, Grinberg Y, Isaia G, Calvo A, Gentile S, et al.; TODEM Study Group. SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Neurology 2012; 79:1556-62; PMID:22972638; http://dx.doi.org/10.1212/ WNL.0b013e31826e25df
-
(2012)
Neurology
, vol.79
, pp. 1556-62
-
-
Rubino, E.1
Rainero, I.2
Chió, A.3
Rogaeva, E.4
Galimberti, D.5
Fenoglio, P.6
Grinberg, Y.7
Isaia, G.8
Calvo, A.9
Gentile, S.10
-
71
-
-
77952533111
-
Vcp/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause ibmpfd
-
PMID:20104022
-
Tresse E, Salomons FA, Vesa J, Bott LC, Kimonis V, Yao TP, Dantuma NP, Taylor JP. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy 2010; 6:217-27; PMID:20104022; http://dx.doi.org/10.4161/auto.6.2. 11014
-
(2010)
Autophagy
, vol.6
, pp. 217-27
-
-
Tresse, E.1
Salomons, F.A.2
Vesa, J.3
Bott, L.C.4
Kimonis, V.5
Yao, T.P.6
Dantuma, N.P.7
Taylor, J.P.8
-
72
-
-
74049124412
-
Valosin-containing protein (vcp) is required for autophagy and is disrupted in vcp disease
-
PMID:20008565
-
Ju JS, Fuentealba RA, Miller SE, Jackson E, PiwnicaWorms D, Baloh RH, Weihl CC. Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease. J Cell Biol 2009; 187:87588; PMID:20008565; http://dx.doi.org/10.1083/jcb.200908115
-
(2009)
J Cell Biol
, vol.187
, pp. 87588
-
-
Ju, J.S.1
Fuentealba, R.A.2
Miller, S.E.3
Jackson, E.4
PiwnicaWorms, D.5
Baloh, R.H.6
Weihl, C.C.7
-
73
-
-
78049244477
-
Vcp associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease
-
PMID:20957154
-
Badadani M, Nalbandian A, Watts GD, Vesa J, Kitazawa M, Su H, Tanaja J, Dec E, Wallace DC, Mukherjee J, et al. VCP associated inclusion body myopathy and paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS One 2010; 5:e13183; PMID:20957154; http://dx.doi.org/10. 1371/journal.pone.0013183
-
(2010)
PLoS One
, vol.5
-
-
Badadani, M.1
Nalbandian, A.2
Watts, G.D.3
Vesa, J.4
Kitazawa, M.5
Su, H.6
Tanaja, J.7
Dec, E.8
Wallace, D.C.9
Mukherjee, J.10
-
74
-
-
77952884683
-
Genome-wide association study identifies variants at csf1, optn and tnfrsf11a as genetic risk factors for paget's disease of bone
-
PMID:20436471
-
Albagha OM, Visconti MR, Alonso N, Langston AL, Cundy T, Dargie R, Dunlop MG, Fraser WD, Hooper MJ, Isaia G, et al. Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone. Nat Genet 2010; 42:520-4; PMID:20436471; http://dx.doi.org/10.1038/ng.562
-
(2010)
Nat Genet
, vol.42
, pp. 520-4
-
-
Albagha, O.M.1
Visconti, M.R.2
Alonso, N.3
Langston, A.L.4
Cundy, T.5
Dargie, R.6
Dunlop, M.G.7
Fraser, W.D.8
Hooper, M.J.9
Isaia, G.10
-
75
-
-
84894492663
-
Optn negatively regulates osteoclast formation in vitro
-
Obaid R, Wani S, Ralston SH, Albagha OM. OPTN negatively regulates osteoclast formation in vitro. Bone 2012; 50(Suppl 1):S92-3; http://dx.doi.org/10.1016/j.bone.2012.02.276
-
(2012)
Bone
, vol.50
, Issue.SUPPL. 1
-
-
Obaid, R.1
Wani, S.2
Ralston, S.H.3
Albagha, O.M.4
-
76
-
-
55449122852
-
Age and pattern of the onset of differential growth among growth plates in rats
-
PMID:18404738
-
Wilsman NJ, Bernardini ES, Leiferman E, Noonan K, Farnum CE. Age and pattern of the onset of differential growth among growth plates in rats. J Orthop Res 2008; 26:1457-65; PMID:18404738; http://dx.doi.org/10.1002/jor.20547
-
(2008)
J Orthop Res
, vol.26
, pp. 1457-65
-
-
Wilsman, N.J.1
Bernardini, E.S.2
Leiferman, E.3
Noonan, K.4
Farnum, C.E.5
-
77
-
-
19544379935
-
The role of matrix vesicles in growth plate development and biomineralization
-
PMID:15569622
-
Anderson HC, Garimella R, Tague SE. The role of matrix vesicles in growth plate development and biomineralization. Front Biosci 2005; 10:822-37; PMID:15569622; http://dx.doi.org/10.2741/1576
-
(2005)
Front Biosci
, vol.10
, pp. 822-37
-
-
Anderson, H.C.1
Garimella, R.2
Tague, S.E.3
-
78
-
-
84859508642
-
Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate
-
PMID:22493717
-
Alvarez-García O, García-López E, Loredo V, GilPena H, Mejía-Gaviria N, Rodríguez-Suárez J, Ordónez FA, Santos F. Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate. PLoS One 2012; 7:e34788; PMID:22493717; http://dx.doi.org/10.1371/ journal.pone.0034788
-
(2012)
PLoS One
, vol.7
-
-
Alvarez-García, O.1
García-López, E.2
Loredo, V.3
GilPena, H.4
Mejía-Gaviria, N.5
Rodríguez-Suárez, J.6
Ordónez, F.A.7
Santos, F.8
-
79
-
-
32644441951
-
Fate of the hypertrophic chondrocyte: Microenvironmental perspectives on apoptosis and survival in the epiphyseal growth plate
-
DOI 10.1002/bdrc.20057
-
Shapiro IM, Adams CS, Freeman T, Srinivas V. Fate of the hypertrophic chondrocyte: microenvironmental perspectives on apoptosis and survival in the epiphyseal growth plate. Birth Defects Res C Embryo Today 2005; 75:330-9; PMID:16425255; http://dx.doi.org/10.1002/bdrc.20057 (Pubitemid 43244621)
-
(2005)
Birth Defects Research Part C - Embryo Today: Reviews
, vol.75
, Issue.4
, pp. 330-339
-
-
Shapiro, I.M.1
Adams, C.S.2
Freeman, T.3
Srinivas, V.4
-
80
-
-
33744764558
-
PTHrP and skeletal development
-
DOI 10.1196/annals.1346.002
-
Kronenberg HM. PTHrP and skeletal development. Ann N Y Acad Sci 2006; 1068:1-13; PMID:16831900; http://dx.doi.org/10.1196/annals.1346.002 (Pubitemid 43824131)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1068
, Issue.1
, pp. 1-13
-
-
Kronenberg, H.M.1
-
81
-
-
59449103444
-
Autophagy in mineralizing tissues: Microenvironmental perspectives
-
PMID:19177014
-
Srinivas V, Bohensky J, Zahm AM, Shapiro IM. Autophagy in mineralizing tissues: microenvironmental perspectives. Cell Cycle 2009; 8:3913; PMID:19177014; http://dx.doi.org/10.4161/cc.8.3.7545
-
(2009)
Cell Cycle
, vol.8
, pp. 3913
-
-
Srinivas, V.1
Bohensky, J.2
Zahm, A.M.3
Shapiro, I.M.4
-
82
-
-
0035499204
-
Hypoxia in cartilage: HIF-1 is essential for chondrocyte growth arrest and survival
-
Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, Johnson RS. Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev 2001; 15:2865-76; PMID:11691837 (Pubitemid 33042056)
-
(2001)
Genes and Development
, vol.15
, Issue.21
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
Johnson, R.S.6
-
83
-
-
33846631265
-
Metabolic consideration of epiphyseal growth: Survival responses in a taxing environment
-
DOI 10.1016/j.bone.2006.09.030, PII S8756328206007071
-
Shapiro IM, Srinivas V. Metabolic consideration of epiphyseal growth: survival responses in a taxing environment. Bone 2007; 40:561-7; PMID:17157572; http://dx.doi.org/10.1016/j.bone.2006.09.030 (Pubitemid 46187214)
-
(2007)
Bone
, vol.40
, Issue.3
, pp. 561-567
-
-
Shapiro, I.M.1
Srinivas, V.2
-
84
-
-
34248532510
-
HIF-1 regulation of chondrocyte apoptosis: Induction of the autophagic pathway
-
Bohensky J, Shapiro IM, Leshinsky S, Terkhorn SP, Adams CS, Srinivas V. HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway. Autophagy 2007; 3:207-14; PMID:17224629 (Pubitemid 46752680)
-
(2007)
Autophagy
, vol.3
, Issue.3
, pp. 207-214
-
-
Bohensky, J.1
Shapiro, I.M.2
Leshinsky, S.3
Terkhorn, S.P.4
Adams, C.S.5
Srinivas, V.6
-
85
-
-
77951259001
-
Chondrocyte autophagy is stimulated by hif-1 dependent ampk activation and mtor suppression
-
PMID:19830459
-
Bohensky J, Leshinsky S, Srinivas V, Shapiro IM. Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression Pediatr Nephrol 2010; 25, 633-42;PMID:19830459;http://dx.doi.org/10.1007/s00467-009- 1310-y
-
(2010)
Pediatr Nephrol
, vol.25
, pp. 633-42
-
-
Bohensky, J.1
Leshinsky, S.2
Srinivas, V.3
Shapiro, I.M.4
-
86
-
-
84856800302
-
Role of ampk-mtor-ulk1/2 in the regulation of autophagy: Cross talk, shortcuts, and feedbacks
-
PMID
-
Alers S, Loffler AS, Wesselborg S, Stork B Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks Mol Cell Biol 2012; 32 2-11; PMID:
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2-11
-
-
Alers, S.1
Loffler, A.S.2
Wesselborg, S.3
Stork, B.4
-
87
-
-
33845425409
-
Expression of HIF prolyl hydroxylase isozymes in growth plate chondrocytes: Relationship between maturation and apoptotic sensitivity
-
DOI 10.1002/jcp.20873
-
Terkhorn SP, Bohensky J, Shapiro IM, Koyama E, Srinivas V. Expression of HIF prolyl hydroxylase isozymes in growth plate chondrocytes: relationship between maturation and apoptotic sensitivity. J Cell Physiol 2007; 210:257-65; PMID:17044072; http://dx.doi.org/10.1002/jcp.20873 (Pubitemid 44904720)
-
(2007)
Journal of Cellular Physiology
, vol.210
, Issue.1
, pp. 257-265
-
-
Terkhorn, S.P.1
Bohensky, J.2
Shapiro, I.M.3
Koyama, E.4
Srinivas, V.5
-
89
-
-
84855577104
-
Overview of the mucopolysaccharidoses
-
PMID:22210669
-
Muenzer J. Overview of the mucopolysaccharidoses. Rheumatology (Oxford) 2011; 50(Suppl 5):v412; PMID:22210669; http://dx.doi.org/10.1093/rheumatology/ ker394
-
(2011)
Rheumatology (Oxford)
, vol.50
, Issue.SUPPL. 5
-
-
Muenzer, J.1
-
90
-
-
0037509873
-
The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases
-
DOI 10.1016/S0092-8674(03)00348-9
-
Cosma MP, Pepe S, Annunziata I, Newbold RF, Grompe M, Parenti G, Ballabio A. The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell 2003; 113:445-56; PMID:12757706; http://dx.doi.org/10.1016/S0092-8674(03)00348-9 (Pubitemid 36588748)
-
(2003)
Cell
, vol.113
, Issue.4
, pp. 445-456
-
-
Cosma, M.P.1
Pepe, S.2
Annunziata, I.3
Newbold, R.F.4
Grompe, M.5
Parenti, G.6
Ballabio, A.7
-
91
-
-
62949116803
-
Lysosomal disorders: From storage to cellular damage
-
PMID:19111581
-
Ballabio A, Gieselmann V. Lysosomal disorders: from storage to cellular damage. Biochim Biophys Acta 2009; 1793:684-96; PMID:19111581; http://dx.doi.org/10.1016/j.bbamcr.2008.12.001
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 684-96
-
-
Ballabio, A.1
Gieselmann, V.2
-
92
-
-
34248353120
-
Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency
-
PMID:17360554
-
Settembre C, Annunziata I, Spampanato C, Zarcone D, Cobellis G, Nusco E, Zito E, Tacchetti C, Cosma MP, Ballabio A. Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency. Proc Natl Acad Sci U S A 2007; 104:450611; PMID:17360554; http://dx.doi.org/10.1073/pnas. 0700382104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 450611
-
-
Settembre, C.1
Annunziata, I.2
Spampanato, C.3
Zarcone, D.4
Cobellis, G.5
Nusco, E.6
Zito, E.7
Tacchetti, C.8
Cosma, M.P.9
Ballabio, A.10
-
93
-
-
53549132810
-
Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of fgf signaling during endochondral ossification
-
PMID:18832069
-
Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G. Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev 2008; 22:2645-50; PMID:18832069; http://dx.doi.org/10. 1101/gad.1711308
-
(2008)
Genes Dev
, vol.22
, pp. 2645-50
-
-
Settembre, C.1
Arteaga-Solis, E.2
McKee, M.D.3
De Pablo, R.4
Al Awqati, Q.5
Ballabio, A.6
Karsenty, G.7
-
94
-
-
84862610496
-
Autophagy contributes to lysosomal storage disorders
-
PMID:22617443
-
Shimada Y, Klionsky DJ. Autophagy contributes to lysosomal storage disorders. Autophagy 2012; 8:7156; PMID:22617443; http://dx.doi.org/10.4161/ auto.19920
-
(2012)
Autophagy
, vol.8
, pp. 7156
-
-
Shimada, Y.1
Klionsky, D.J.2
-
95
-
-
84862602473
-
Autophagy in lysosomal storage disorders
-
PMID:22647656
-
Lieberman AP, Puertollano R, Raben N, Slaugenhaupt S, Walkley SU, Ballabio A. Autophagy in lysosomal storage disorders. Autophagy 2012; 8:71930; PMID:22647656; http://dx.doi.org/10.4161/auto.19469
-
(2012)
Autophagy
, vol.8
, pp. 71930
-
-
Lieberman, A.P.1
Puertollano, R.2
Raben, N.3
Slaugenhaupt, S.4
Walkley, S.U.5
Ballabio, A.6
-
96
-
-
78149282263
-
Lysosomal fusion and snare function are impaired by cholesterol accumulation in lysosomal storage disorders
-
PMID:20871593
-
Fraldi A, Annunziata F, Lombardi A, Kaiser HJ, Medina DL, Spampanato C, Fedele AO, Polishchuk R, Sorrentino NC, Simons K, et al. Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders. EMBO J 2010; 29:3607-20; PMID:20871593; http://dx.doi.org/10.1038/ emboj.2010.237
-
(2010)
EMBO J
, vol.29
, pp. 3607-20
-
-
Fraldi, A.1
Annunziata, F.2
Lombardi, A.3
Kaiser, H.J.4
Medina, D.L.5
Spampanato, C.6
Fedele, A.O.7
Polishchuk, R.8
Sorrentino, N.C.9
Simons, K.10
-
97
-
-
84861994775
-
Effects of aging on articular cartilage homeostasis
-
PMID:22487298
-
Lotz M, Loeser RF. Effects of aging on articular cartilage homeostasis. Bone 2012; 51:241-8; PMID:22487298; http://dx.doi.org/10.1016/j.bone.2012.03.023
-
(2012)
Bone
, vol.51
, pp. 241-8
-
-
Lotz, M.1
Loeser, R.F.2
-
98
-
-
77953536591
-
Macroscopic assessment of cartilage shear: Effects of counter-surface roughness, synovial fluid lubricant, and compression offset
-
PMID:20189572
-
Nguyen QT, Wong BL, Chun J, Yoon YC, Talke FE, Sah RL. Macroscopic assessment of cartilage shear: effects of counter-surface roughness, synovial fluid lubricant, and compression offset. J Biomech 2010; 43:1787-93; PMID:20189572; http://dx.doi.org/10.1016/j.jbiomech.2010.02.014
-
(2010)
J Biomech
, vol.43
, pp. 1787-93
-
-
Nguyen, Q.T.1
Wong, B.L.2
Chun, J.3
Yoon, Y.C.4
Talke, F.E.5
Sah, R.L.6
-
99
-
-
0028839263
-
Damage to type ii collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration
-
PMID:8675657
-
Hollander AP, Pidoux I, Reiner A, Rorabeck C, Bourne R, Poole AR. Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995; 96:2859-69; PMID:8675657; http://dx.doi.org/10.1172/JCI118357
-
(1995)
J Clin Invest
, vol.96
, pp. 2859-69
-
-
Hollander, A.P.1
Pidoux, I.2
Reiner, A.3
Rorabeck, C.4
Bourne, R.5
Poole, A.R.6
-
100
-
-
77955343925
-
Cartilage cell clusters
-
PMID:20506158
-
Lotz MK, Otsuki S, Grogan SP, Sah R, Terkeltaub R, D'Lima D. Cartilage cell clusters. Arthritis Rheum 2010; 62:2206-18; PMID:20506158; http://dx.doi.org/10.1002/art.27528
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2206-18
-
-
Lotz, M.K.1
Otsuki, S.2
Grogan, S.P.3
Sah, R.4
Terkeltaub, R.5
D'Lima, D.6
-
101
-
-
77951666929
-
Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of osteoarthritis within an experimental model
-
PMID:20091349
-
Almonte-Becerril M, Navarro-Garcia F, GonzalezRobles A, Vega-Lopez MA, Lavalle C, Kouri JB. Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model. Apoptosis 2010; 15:631-8; PMID:20091349; http://dx.doi.org/10.1007/s10495-010-0458-z
-
(2010)
Apoptosis
, vol.15
, pp. 631-8
-
-
Almonte-Becerril, M.1
Navarro-Garcia, F.2
GonzalezRobles, A.3
Vega-Lopez, M.A.4
Lavalle, C.5
Kouri, J.B.6
-
102
-
-
66049155861
-
Regulation of autophagy in human and murine cartilage: Hypoxia-inducible factor 2 suppresses chondrocyte autophagy
-
140615 PMID
-
Bohensky J, Terkhorn SP, Freeman TA, Adams CS, Garcia JA, Shapiro IM, Srinivas V. Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy. Arthritis Rheum 2009; 60:140615; PMID:19404942; http://dx.doi.org/10.1002/art.24444
-
(2009)
Arthritis Rheum
, vol.60
-
-
Bohensky, J.1
Terkhorn, S.P.2
Freeman, T.A.3
Adams, C.S.4
Garcia, J.A.5
Shapiro, I.M.6
Srinivas, V.7
-
103
-
-
0034613294
-
Age-related decline in chaperonemediated autophagy
-
PMID:10806201
-
Cuervo AM, Dice JF. Age-related decline in chaperonemediated autophagy. J Biol Chem 2000; 275:31505-13; PMID:10806201; http://dx.doi.org/10.1074/jbc. M002102200
-
(2000)
J Biol Chem
, vol.275
, pp. 31505-13
-
-
Cuervo, A.M.1
Dice, J.F.2
-
104
-
-
79952451523
-
The role of mitochondria in osteoarthritis
-
PMID:21200395
-
Blanco FJ, Rego I, Ruiz-Romero C. The role of mitochondria in osteoarthritis. Nat Rev Rheumatol 2011; 7:161-9; PMID:21200395; http://dx.doi.org/10.1038/nrrheum.2010.213
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 161-9
-
-
Blanco, F.J.1
Rego, I.2
Ruiz-Romero, C.3
-
105
-
-
76549113814
-
Mitochondrial dna damage is involved in apoptosis caused by pro-inflammatory cytokines in human oa chondrocytes
-
PMID:19822235
-
Kim J, Xu M, Xo R, Mates A, Wilson GL, Pearsall AW 4th, Grishko V. Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes. Osteoarthritis Cartilage 2010; 18:424-32; PMID:19822235; http://dx.doi.org/10.1016/j.joca.2009.09.008
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 424-32
-
-
Kim, J.1
Xu, M.2
Xo, R.3
Mates, A.4
Wilson, G.L.5
Pearsall IV, A.W.6
Grishko, V.7
-
106
-
-
79955161193
-
Mitochondria: Sovereign of inflammation?
-
PMID:21469137
-
Tschopp J. Mitochondria: Sovereign of inflammation? Eur J Immunol 2011; 41:1196-202; PMID:21469137; http://dx.doi.org/10.1002/eji.201141436
-
(2011)
Eur J Immunol
, vol.41
, pp. 1196-202
-
-
Tschopp, J.1
-
107
-
-
84861830188
-
Autophagy modulates osteoarthritisrelated gene expression in human chondrocytes
-
PMID:22147463
-
Sasaki H, Takayama K, Matsushita T, Ishida K, Kubo S, Matsumoto T, Fujita N, Oka S, Kurosaka M, Kuroda R. Autophagy modulates osteoarthritisrelated gene expression in human chondrocytes. Arthritis Rheum 2012; 64:1920-8; PMID:22147463; http://dx.doi.org/10.1002/art.34323
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1920-1928
-
-
Sasaki, H.1
Takayama, K.2
Matsushita, T.3
Ishida, K.4
Kubo, S.5
Matsumoto, T.6
Fujita, N.7
Oka, S.8
Kurosaka, M.9
Kuroda, R.10
-
108
-
-
76549113814
-
Mitochondrial dna damage is involved in apoptosis caused by pro-inflammatory cytokines in human oa chondrocytes
-
PMID:19822235
-
Kim J, Xu M, Xo R, Mates A, Wilson GL, Pearsall AW 4th, Grishko V. Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes. Osteoarthritis Cartilage 2010; 18:424-32; PMID:19822235; http://dx.doi.org/10.1016/j.joca.2009.09.008
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 424-32
-
-
Kim, J.1
Xu, M.2
Xo, R.3
Mates, A.4
Wilson, G.L.5
Pearsall IV, A.W.6
Grishko, V.7
-
109
-
-
77953208836
-
Transcriptional regulation of endochondral ossification by hif-2alpha during skeletal growth and osteoarthritis development
-
PMID:20495570
-
Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, et al. Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat Med 2010; 16:67886; PMID:20495570; http://dx.doi.org/10.1038/ nm.2146
-
(2010)
Nat Med
, vol.16
, pp. 67886
-
-
Saito, T.1
Fukai, A.2
Mabuchi, A.3
Ikeda, T.4
Yano, F.5
Ohba, S.6
Nishida, N.7
Akune, T.8
Yoshimura, N.9
Nakagawa, T.10
-
110
-
-
77953183739
-
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
-
PMID:20495569
-
Yang S, Kim J, Ryu JH, Oh H, Chun CH, Kim BJ, Min BH, Chun JS. Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. Nat Med 2010; 16:687-93; PMID:20495569; http://dx.doi.org/10.1038/nm.2153
-
(2010)
Nat Med
, vol.16
, pp. 687-93
-
-
Yang, S.1
Kim, J.2
Ryu, J.H.3
Oh, H.4
Chun, C.H.5
Kim, B.J.6
Min, B.H.7
Chun, J.S.8
-
112
-
-
84862545919
-
Insights on biology and pathology of hif1a/-2a, tgfβ/bmp, wnt/β-catenin, and nf-b pathways in osteoarthritis
-
PMID:22646092
-
Wu L, Huang X, Li L, Huang H, Xu R, Luyten W. Insights on biology and pathology of HIF1a/-2a, TGFβ/BMP, Wnt/β-catenin, and NF-B pathways in osteoarthritis. Curr Pharm Des 2012; 18:3293-312; PMID:22646092; http://dx.doi.org/10.2174/1381612811209023293
-
(2012)
Curr Pharm Des
, vol.18
, pp. 3293-312
-
-
Wu, L.1
Huang, X.2
Li, L.3
Huang, H.4
Xu, R.5
Luyten, W.6
-
113
-
-
77953183739
-
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
-
PMID:20495569
-
Yang S, Kim J, Ryu JH, Oh H, Chun CH, Kim BJ, Min BH, Chun JS. Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. Nat Med 2010; 16:687-93; PMID:20495569; http://dx.doi.org/10.1038/nm.2153
-
(2010)
Nat Med
, vol.16
, pp. 687-93
-
-
Yang, S.1
Kim, J.2
Ryu, J.H.3
Oh, H.4
Chun, C.H.5
Kim, B.J.6
Min, B.H.7
Chun, J.S.8
-
114
-
-
84863989011
-
Tnfa-mediated apoptosis in human osteoarthritic chondrocytes sensitized by pi3knfb inhibitor, not mtor inhibitor
-
PMID:21479603
-
Li D, Wu Z, Duan Y, Hao D, Zhang X, Luo H, Chen B, Qiu G. TNFa-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3KNF?B inhibitor, not mTOR inhibitor. Rheumatol Int 2012; 32:2017-22; PMID:21479603; http://dx.doi.org/10.1007/s00296-011-1929-4
-
(2012)
Rheumatol Int
, vol.32
, pp. 2017-22
-
-
Li, D.1
Wu, Z.2
Duan, Y.3
Hao, D.4
Zhang, X.5
Luo, H.6
Chen, B.7
Qiu, G.8
-
115
-
-
77956923738
-
Analysis of receptor tyrosine kinases (rtks) and downstream pathways in chordomas
-
PMID:20164240
-
Tamborini E, Virdis E, Negri T, Orsenigo M, Brich S, Conca E, Gronchi A, Stacchiotti S, Manenti G, Casali PG, et al. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol 2010; 12:776-89; PMID:20164240; http://dx.doi.org/10.1093/neuonc/noq003
-
(2010)
Neuro Oncol
, vol.20
, pp. 776-89
-
-
Tamborini, E.1
Virdis, E.2
Negri, T.3
Orsenigo, M.4
Brich, S.5
Conca, E.6
Gronchi, A.7
Stacchiotti, S.8
Manenti, G.9
Casali, P.G.10
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