-
1
-
-
77950362382
-
The inflammasomes
-
Schroder, K. and Tschopp, J., The inflammasomes. Cell 2010. 140: 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
2
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis, B. K., Wen, H. and Ting, J. P.-Y., The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 2011. 29: 707-735.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.-Y.3
-
3
-
-
79955148909
-
A clinical perspective of interleukin-1β as the gatekeeper of inflammation
-
Dinarello, C. A., A clinical perspective of interleukin-1β as the gatekeeper of inflammation Eur. J. Immunol. 2011. 41: 1203-1217.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1203-1217
-
-
Dinarello, C.A.1
-
4
-
-
74549184092
-
The NLRP3 inflammasome: a sensor for metabolic danger?
-
Schroder, K., Zhou, R. and Tschopp, J., The NLRP3 inflammasome: a sensor for metabolic danger? Science 2010. 327: 296-300.
-
(2010)
Science
, vol.327
, pp. 296-300
-
-
Schroder, K.1
Zhou, R.2
Tschopp, J.3
-
5
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A. and Latz, E., Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 2008. 9: 847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
6
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert, C., Petrilli, V., Van Bruggen, R., Steele, C., Mossman, B. T. and Tschopp, J., Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008. 320: 674-677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
7
-
-
70349413073
-
CA-074Me protection against anthrax lethal toxin
-
Newman, Z. L., Leppla, S. H. and Moayeri, M., CA-074Me protection against anthrax lethal toxin. Infect. Immun. 2009. 77: 4327-4336.
-
(2009)
Infect. Immun.
, vol.77
, pp. 4327-4336
-
-
Newman, Z.L.1
Leppla, S.H.2
Moayeri, M.3
-
8
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Pétrilli, V., Papin, S., Dostert, C., Mayor, A., Martinon, F. and Tschopp, J., Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 2007. 14: 1583-1589.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1583-1589
-
-
Pétrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
9
-
-
2942744672
-
Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells
-
Sato, T., Machida, T., Takahashi, S., Iyama, S., Sato, Y., Kuribayashi, K., Takada, K. et al., Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells. J. Immunol. 2004. 173: 285-296.
-
(2004)
J. Immunol.
, vol.173
, pp. 285-296
-
-
Sato, T.1
Machida, T.2
Takahashi, S.3
Iyama, S.4
Sato, Y.5
Kuribayashi, K.6
Takada, K.7
-
10
-
-
77956574503
-
NOX-free inflammasome activation
-
Latz, E., NOX-free inflammasome activation. Blood 2010. 116: 1393-1394.
-
(2010)
Blood
, vol.116
, pp. 1393-1394
-
-
Latz, E.1
-
11
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J. A., Rathinam, V. A., Lee, S. J., Dolinay, T., Lam, H. C., Englert, J. A. et al., Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 2011. 12: 222-230.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
-
12
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A. S., Menu, P. and Tschopp, J., A role for mitochondria in NLRP3 inflammasome activation. Nature 2010. 469: 221-225.
-
(2010)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
13
-
-
0842345400
-
VDAC: the channel at the interface between mitochondria and the cytosol
-
Colombini, M., VDAC: the channel at the interface between mitochondria and the cytosol. Mol. Cell. Biochem. 2004. 256-257: 107-115.
-
(2004)
Mol. Cell. Biochem.
, vol.256-257
, pp. 107-115
-
-
Colombini, M.1
-
14
-
-
59449097391
-
MAM: more than just a housekeeper
-
Hayashi, T., Rizzuto, R., Hajnoczky, G. and Su, T. P., MAM: more than just a housekeeper. Trends Cell Biol. 2009. 19: 81-88.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 81-88
-
-
Hayashi, T.1
Rizzuto, R.2
Hajnoczky, G.3
Su, T.P.4
-
15
-
-
4544235673
-
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
-
Brookes, P. S., Yoon, Y., Robotham, J. L., Anders, M. W. and Sheu, S. S., Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am. J. Physiol. Cell Physiol. 2004. 287: C817-C833.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.S.5
-
16
-
-
67549101188
-
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
-
Zhang, J. and Ney, P. A., Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ. 2009. 16: 939-946.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 939-946
-
-
Zhang, J.1
Ney, P.A.2
-
17
-
-
34247345833
-
The apoptosome: signalling platform of cell death
-
Riedl, S. J. and Salvesen, G. S., The apoptosome: signalling platform of cell death. Nat. Rev. Mol. Cell Biol. 2007. 8: 405-413.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
18
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou, R., Tardivel, A., Thorens, B., Choi, I. and Tschopp, J., Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat. Immunol. 2010. 11: 136-140.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
19
-
-
77950486855
-
Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein
-
Saxena, G., Chen, J. and Shalev, A., Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein. J. Biol. Chem. 2010. 285: 3997-4005.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3997-4005
-
-
Saxena, G.1
Chen, J.2
Shalev, A.3
-
20
-
-
53849116110
-
Lack of TXNIP protects beta-cells against glucotoxicity
-
Shalev, A., Lack of TXNIP protects beta-cells against glucotoxicity. Biochem. Soc. Trans. 2008. 36: 963-965.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 963-965
-
-
Shalev, A.1
-
21
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux, D. and Gabel, C. A., Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 1994. 269: 15195-15203.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
22
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P. et al., Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006. 440: 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
-
23
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve, D. A., Petrilli, V., Zaiss, A. K., White, L. R., Clark, S. A., Ross, P. J., Parks, R. J. and Tschopp, J., The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 2008. 452: 103-107.
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
24
-
-
70449727077
-
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
-
Lamkanfi, M., Mueller, J. L., Vitari, A. C., Misaghi, S., Fedorova, A., Deshayes, K., Lee, W. P. et al., Glyburide inhibits the Cryopyrin/Nalp3 inflammasome. J. Cell Biol. 2009. 187: 61-70.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 61-70
-
-
Lamkanfi, M.1
Mueller, J.L.2
Vitari, A.C.3
Misaghi, S.4
Fedorova, A.5
Deshayes, K.6
Lee, W.P.7
-
25
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
Masters, S. L., Dunne, A., Subramanian, S. L., Hull, R. L., Tannahill, G. M., Sharp, F. A., Becker, C. et al., Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat. Immunol. 2010. 11: 897-904.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
-
26
-
-
0035834691
-
Physiological concentrations of K+inhibit cytochrome c-dependent formation of the apoptosome
-
Cain, K., Langlais, C., Sun, X. M., Brown, D. G. and Cohen, G. M., Physiological concentrations of K+inhibit cytochrome c-dependent formation of the apoptosome. J. Biol. Chem. 2001. 276: 41985-41990.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41985-41990
-
-
Cain, K.1
Langlais, C.2
Sun, X.M.3
Brown, D.G.4
Cohen, G.M.5
-
27
-
-
33846300290
-
Mitochondrial Ca2+-induced K+influx increases respiration and enhances ROS production while maintaining membrane potential
-
Heinen, A., Camara, A. K. S., Aldakkak, M., Rhodes, S. S., Riess, M. L. and Stowe, D. F., Mitochondrial Ca2+-induced K+influx increases respiration and enhances ROS production while maintaining membrane potential. Am. J. Physiol. Cell Physiol. 2007. 292: C148-C156.
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.292
-
-
Heinen, A.1
Camara, A.K.S.2
Aldakkak, M.3
Rhodes, S.S.4
Riess, M.L.5
Stowe, D.F.6
-
28
-
-
17744367054
-
Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis
-
Minn, A. H., Hafele, C. and Shalev, A., Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis. Endocrinology 2005. 146: 2397-2405.
-
(2005)
Endocrinology
, vol.146
, pp. 2397-2405
-
-
Minn, A.H.1
Hafele, C.2
Shalev, A.3
-
29
-
-
34249660144
-
TXNIP regulates peripheral glucose metabolism in humans
-
Parikh, H., Carlsson, E., Chutkow, W. A., Johansson, L. E., Storgaard, H., Poulsen, P., Saxena, R. et al., TXNIP regulates peripheral glucose metabolism in humans. PLoS Med. 2007. 4: e158.
-
(2007)
PLoS Med.
, vol.4
-
-
Parikh, H.1
Carlsson, E.2
Chutkow, W.A.3
Johansson, L.E.4
Storgaard, H.5
Poulsen, P.6
Saxena, R.7
-
30
-
-
41649100341
-
Txnip balances metabolic and growth signaling via PTEN disulfide reduction
-
Hui, S. T., Andres, A. M., Miller, A. K., Spann, N. J., Potter, D. W., Post, N. M., Chen, A. Z. et al., Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc. Natl. Acad. Sci. USA 2008. 105: 3921-3926.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3921-3926
-
-
Hui, S.T.1
Andres, A.M.2
Miller, A.K.3
Spann, N.J.4
Potter, D.W.5
Post, N.M.6
Chen, A.Z.7
-
31
-
-
67649641767
-
Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function
-
Oka, S., Yoshihara, E., Bizen-Abe, A., Liu, W., Watanabe, M., Yodoi, J. and Masutani, H., Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function. Endocrinology 2009. 150: 1225-1234.
-
(2009)
Endocrinology
, vol.150
, pp. 1225-1234
-
-
Oka, S.1
Yoshihara, E.2
Bizen-Abe, A.3
Liu, W.4
Watanabe, M.5
Yodoi, J.6
Masutani, H.7
-
32
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
Stienstra, R., Joosten, L. A., Koenen, T., van Tits, B., van Diepen, J. A., van den Berg, S. A., Rensen, P. C. et al., The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab. 2010. 12: 593-605.
-
(2010)
Cell Metab.
, vol.12
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.A.2
Koenen, T.3
van Tits, B.4
van Diepen, J.A.5
van den Berg, S.A.6
Rensen, P.C.7
-
33
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar, B., Youm, Y. H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E. et al., The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat. Med. 2011. 17: 179-188.
-
(2011)
Nat. Med.
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
-
34
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
Maedler, K., Sergeev, P., Ris, F., Oberholzer, J., Joller-Jemelka, H. I., Spinas, G. A., Kaiser, N. et al., Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J. Clin. Invest. 2002. 110: 851-860.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
Joller-Jemelka, H.I.5
Spinas, G.A.6
Kaiser, N.7
-
35
-
-
37549002511
-
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
Shao, W., Yeretssian, G., Doiron, K., Hussain, S. N. and Saleh, M., The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J. Biol. Chem. 2007. 282: 36321-36329.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
36
-
-
53249131271
-
Medication-induced mitochondrial damage and disease
-
Neustadt, J. and Pieczenik, S. R., Medication-induced mitochondrial damage and disease. Mol. Nutr. Food Res. 2008. 52: 780-788.
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 780-788
-
-
Neustadt, J.1
Pieczenik, S.R.2
-
37
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
Cho, J. H., The genetics and immunopathogenesis of inflammatory bowel disease. Nat. Rev. Immunol. 2008. 8: 458-466.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
38
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
Maeda, S., Hsu, L. C., Liu, H., Bankston, L. A., Iimura, M., Kagnoff, M. F., Eckmann, L. and Karin, M., Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 2005. 307: 734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
39
-
-
0042855191
-
Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice
-
Ishikura, T., Kanai, T., Uraushihara, K., Iiyama, R., Makita, S., Totsuka, T., Yamazaki, M. et al., Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice. J. Gastroenterol. Hepatol. 2003. 18: 960-969.
-
(2003)
J. Gastroenterol. Hepatol.
, vol.18
, pp. 960-969
-
-
Ishikura, T.1
Kanai, T.2
Uraushihara, K.3
Iiyama, R.4
Makita, S.5
Totsuka, T.6
Yamazaki, M.7
-
40
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
Dupaul-Chicoine, J., Yeretssian, G., Doiron, K., Bergstrom, K. S. B., McIntire, C. R., LeBlanc, P. M., Meunier, C. et al., Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity 2010. 32: 367-378.
-
(2010)
Immunity
, vol.32
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
Yeretssian, G.2
Doiron, K.3
Bergstrom, K.S.B.4
McIntire, C.R.5
LeBlanc, P.M.6
Meunier, C.7
-
41
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki, M. H., Boyd, K. L., Vogel, P., Kastan, M. B., Lamkanfi, M., Kanneganti, T. D., The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010. 32: 379-391.
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
42
-
-
77953122347
-
Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease
-
Roberts, R. L., Topless, R. K. G., Phipps-Green, A. J., Gearry, R. B., Barclay, M. L. and Merriman, T. R., Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease. Genes Immun. 2010. 11: 351-356.
-
(2010)
Genes Immun.
, vol.11
, pp. 351-356
-
-
Roberts, R.L.1
Topless, R.K.G.2
Phipps-Green, A.J.3
Gearry, R.B.4
Barclay, M.L.5
Merriman, T.R.6
-
43
-
-
66949174089
-
Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
-
Schoultz, I., Verma, D., Halfvarsson, J., Törkvist, L., Fredrikson, M., Sjöqvist, U., Lördal, M. et al., Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am. J. Gastroenterol. 2009. 104: 1180-1188.
-
(2009)
Am. J. Gastroenterol.
, vol.104
, pp. 1180-1188
-
-
Schoultz, I.1
Verma, D.2
Halfvarsson, J.3
Törkvist, L.4
Fredrikson, M.5
Sjöqvist, U.6
Lördal, M.7
-
44
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos, L., Carneiro, L., Ramjeet, M., Hussey, S., Kim, Y., Magalhães, J., Yuan, L. et al., Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat. Immunol. 2009. 11: 55-62.
-
(2009)
Nat. Immunol.
, vol.11
, pp. 55-62
-
-
Travassos, L.1
Carneiro, L.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.5
Magalhães, J.6
Yuan, L.7
-
45
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh, T., Fujita, N., Jang, M. H., Uematsu, S., Yang, B.-G., Satoh, T., Omori, H. et al., Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008. 456: 264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.-G.5
Satoh, T.6
Omori, H.7
-
46
-
-
34250716407
-
Mitochondrial dysfunction in Parkinson's disease
-
Schapira, A. H., Mitochondrial dysfunction in Parkinson's disease. Cell Death Differ. 2007. 14: 1261-1266.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1261-1266
-
-
Schapira, A.H.1
-
47
-
-
46849088998
-
Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
-
Pott Godoy, M. C., Tarelli, R., Ferrari, C. C., Sarchi, M. I. and Pitossi, F. J., Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease. Brain 2008. 131: 1880-1894.
-
(2008)
Brain
, vol.131
, pp. 1880-1894
-
-
Pott Godoy, M.C.1
Tarelli, R.2
Ferrari, C.C.3
Sarchi, M.I.4
Pitossi, F.J.5
-
48
-
-
34247595320
-
Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism
-
Yi, P.-L., Tsai, C.-H., Lu, M.-K., Liu, H.-J., Chen, Y.-C. and Chang, F.-C., Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism. Sleep 2007. 30: 413-425.
-
(2007)
Sleep
, vol.30
, pp. 413-425
-
-
Yi, P.-L.1
Tsai, C.-H.2
Lu, M.-K.3
Liu, H.-J.4
Chen, Y.-C.5
Chang, F.-C.6
-
49
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell, B. B. and Shulman, G. I., Mitochondrial dysfunction and type 2 diabetes. Science 2005. 307: 384-387.
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
50
-
-
0028558576
-
The development of mitochondrial medicine
-
Luft, R., The development of mitochondrial medicine. Proc. Natl. Acad. Sci. USA 1994. 91: 8731-8738.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8731-8738
-
-
Luft, R.1
-
51
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, T. and Donath, M. Y., Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl. J. Med. 2007. 356: 1517-1526.
-
(2007)
N Engl. J. Med.
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Vølund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
52
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen, I. C., Scull, M. A., Moore, C. B., Holl, E. K., McElvania-TeKippe, E., Taxman, D. J., Guthrie, E. H. et al., The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009. 30: 556-565.
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
Holl, E.K.4
McElvania-TeKippe, E.5
Taxman, D.J.6
Guthrie, E.H.7
-
53
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellular M2 ion channel
-
Ichinohe, T., Pang, I. K. and Iwasaki, A., Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nat. Immunol. 2010. 11: 404-410.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
54
-
-
34548278018
-
Toxicity of influenza A virus matrix protein 2 for mammalian cells is associated with its intrinsic proton-channeling activity
-
Ilyinskii, P. O., Gabai, V. L., Sunyaev, S. R., Thoidis, G. and Shneider, A. M., Toxicity of influenza A virus matrix protein 2 for mammalian cells is associated with its intrinsic proton-channeling activity. Cell Cycle 2007. 6: 2043-2047.
-
(2007)
Cell Cycle
, vol.6
, pp. 2043-2047
-
-
Ilyinskii, P.O.1
Gabai, V.L.2
Sunyaev, S.R.3
Thoidis, G.4
Shneider, A.M.5
|