Metabolic consideration of epiphyseal growth: Survival responses in a taxing environment

Bone

Volumn 40, Issue 3, 2007, Pages 561-567

  Shapiro, Irving M ^a   Srinivas, Vickram ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Akt; AMPK; Chondrocyte; Epiphyseal growth plate; HIF; Metabolism; mTOR; Oxygen; PHD

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

AEROBIC METABOLISM; ARTICULAR CARTILAGE; BONE DEVELOPMENT; BONE TISSUE; CARTILAGE CELL; ENERGY METABOLISM; EPIPHYSEAL CARTILAGE; EXTRACELLULAR MATRIX; GROWTH PLATE; HUMAN; MEDICAL LITERATURE; METABOLIC STRESS; OSSIFICATION; REVIEW; SURVIVAL;

ANIMALS; CELL SURVIVAL; CHONDROCYTES; GROWTH PLATE; HUMANS; OXYGEN;

EID: 33846631265     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.09.030     Document Type: Review

References (30)

1. Farnum C.E., Turgai J., and Wilsman N.J. Visualization of living terminal hypertrophic chondrocytes of growth plate cartilage in situ by differential interference contrast microscopy and time-lapse cinematography. J. Orthop. Res. 8 (1990) 750-763
2. Hunziker E.B. Growth plate structure and function. Pathol. Immunopathol. Res. 7 (1988) 9-13
3. del Valle A.E., and Aledo J.C. What process is glycolytic stoichiometry optimal for?. J. Mol. Evol. 62 (2006) 488-495
4. Farnum C.E., Lenox M., Zipfel W., Horton W., and Williams R. In vivo delivery of fluoresceinated dextrans to the murine growth plate: imaging of three vascular routes by multiphoton microscopy. Anat. Rec. A, Discov. Mol. Cell. Evol. Biol. 288 (2006) 91-103
5. Wirth T., Syed Ali M.M., Rauer C., Suss D., Griss P., and Syed A.S. The blood supply of the growth plate and the epiphysis: a comparative scanning electron microscopy and histological experimental study in growing sheep. Calcif. Tissue Int. 70 (2002) 312-319
6. Brighton C.T., and Heppenstall R.B. Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. J. Bone Joint Surg. Am. 53 (1971) 719-728
7. Shapiro I.M., Mansfield K.D., Evans S.M., Lord E.M., and Koch C.J. Chondrocytes in the endochondral growth cartilage are not hypoxic. Am. J. Physiol. 272 (1997) t-43
8. Schipani E., Ryan H.E., Didrickson S., Kobayashi T., Knight M., and Johnson R.S. Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 15 (2001) 2865-2876
9. Haselgrove J.C., Shapiro I.M., and Silverton S.F. Computer modeling of the oxygen supply and demand of cells of the avian growth cartilage. Am. J. Physiol. 265 (1993) t-506
10. Heywood H.K., Bader D.L., and Lee D.A. Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration. J. Cell. Physiol. 206 (2006) 402-410
11. Hochachka P.W., and Lutz P.L. Mechanism, origin, and evolution of anoxia tolerance in animals. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 130 (2001) 435-459
12. Otte P. Basic Cell Metab.olism of articular cartilage. Z. Rheumatol. 50 5 (1991) 304-312
13. Cryer P.E. Hypoglycaemia: the limiting factor in the glycaemic management of the critically ill?. Diabetologia 49 (2006) 1722-1725
14. Urban J.P. The chondrocyte: a cell under pressure. Br. J. Rheumatol. 33 (1994) 901-908
15. Rutz H.P. A biophysical basis of enhanced interstitial fluid pressure in tumors. Med. Hypotheses 53 (1999) 526-529
16. Schofield C.J., and Ratcliffe P.J. Oxygen sensing by HIF hydroxylases. Nat. Rev. Mol. Cell Biol. 5 (2004) 343-354
17. Schofield C.J., and Ratcliffe P.J. Signalling hypoxia by HIF hydroxylases. Biochem. Biophys. Res. Commun. 338 (2005) 617-626
18. Stolze I.P., Mole D.R., and Ratcliffe P.J. Regulation of HIF: prolyl hydroxylases. Novartis Found. Symp. 272 (2006) 15-25
19. Terkhorn S.P., Bohensky J., Shapiro I.M., Koyoma E., and Srinivas V. Expression of HIF prolyl hydroxylase isozymes in growth plate chondrocytes: relationship between maturation and apoptotic sensitivity. J. Cell Physiol. 210 (2007) 257-265
20. Iliopoulos O., Kibel A., Gray S., and Kaelin Jr. W.G. Tumour suppression by the human von Hippel-Lindau gene product. Nat. Med. 1 (1995) 822-826
21. Pfander D., Kobayashi T., Knight M.C., Zelzer E., Chan D.A., Olsen B.R., et al. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development 131 (2004) 2497-2508
22. Lahiri S., Roy A., Baby S.M., Hoshi T., Semenza G.L., and Prabhakar N.R. Oxygen sensing in the body. Prog. Biophys. Mol. Biol. 91 (2006) 249-286
23. Semenza G.L., Shimoda L.A., and Prabhakar N.R. Regulation of gene expression by HIF-1. Novartis Found. Symp. 272 (2006) 2-8
24. Kim J.W., Tchernyshyov I., Semenza G.L., and Dang C.V. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 3 (2006) 177-185
25. Buzzai M., Bauer D.E., Jones R.G., DeBerardinis R.J., Hatzivassiliou G., Elstrom R.L., et al. The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene 24 (2005) 4165-4173
26. Thompson J.E., and Thompson C.B. Putting the rap on Akt37. J. Clin. Oncol. 22 (2004) 4217-4226
27. Ellisen L.W. Growth control under stress: mTOR regulation through the REDD1-TSC pathway. Cell Cycle 4 (2005) 1500-1502
28. Schwarzer R., Tondera D., Arnold W., Giese K., Klippel A., and Kaufmann J. REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene 24 (2005) 1138-1149
29. Sofer A., Lei K., Johannessen C.M., and Ellisen L.W. Regulation of mTOR and cell growth in response to energy stress by REDD. Mol. Cell. Biol. 25 (2005) 5834-5845
30. Jones R.G., Plas D.R., Kubek S., Buzzai M., Mu J., Xu Y., et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol. Cell 18 (2005) 283-293