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Volumn 91, Issue 2, 2012, Pages 97-113

Pathogenesis of paget disease of bone

Author keywords

Cartilage; Osteoclast; Paget disease of bone

Indexed keywords

OSTEOPROTEGERIN; PROTEIN P62; PROTEIN P97; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

EID: 84866001357     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-012-9599-0     Document Type: Review
Times cited : (113)

References (160)
  • 2
    • 0018968492 scopus 로고
    • Bone histomorphometry in paget's disease. Quantitative and dynamic analysis of pagetic and nonpagetic bone tissue
    • Meunier PJ, Coindre JM, Edouard CM, Arlot ME (1980) Bone histomorphometry in Paget's disease. Quantitative and dynamic analysis of pagetic and nonpagetic bone tissue. Arthritis Rheum 23:1095-1103
    • (1980) Arthritis Rheum , vol.23 , pp. 1095-1103
    • Meunier, P.J.1    Coindre, J.M.2    Edouard, C.M.3    Arlot, M.E.4
  • 3
    • 70349764552 scopus 로고    scopus 로고
    • The p62 p392l mutation linked to paget's disease induces activation of human osteoclasts
    • Chamoux E, Couture J, BissonM,Morissette J, Brown JP, Roux S (2009) The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts. Mol Endocrinol 23:1668-1680
    • (2009) Mol Endocrinol , vol.23 , pp. 1668-1680
    • Chamoux, E.1    Couture, J.2    Bisson, M.3    Morissette, J.4    Brown, J.P.5    Roux, S.6
  • 5
    • 53349165206 scopus 로고    scopus 로고
    • Pathogenesis of paget's disease of bone
    • Ralston SH (2008) Pathogenesis of Paget's disease of bone. Bone 43:819-825
    • (2008) Bone , vol.43 , pp. 819-825
    • Ralston, S.H.1
  • 6
    • 0021622917 scopus 로고
    • The epidemiology of paget's disease of bone
    • Barker DJ (1984) The epidemiology of Paget's disease of bone. Br Med Bull 40:396-400
    • (1984) Br Med Bull , vol.40 , pp. 396-400
    • Barker, D.J.1
  • 7
    • 0019965276 scopus 로고
    • European distribution of paget's disease of bone
    • Detheridge FM, Guyer PB, Barker DJ (1982) European distribution of Paget's disease of bone. Br Med J 285:1005-1008
    • (1982) Br Med J , vol.285 , pp. 1005-1008
    • Detheridge, F.M.1    Guyer, P.B.2    Barker, D.J.3
  • 10
    • 77955750436 scopus 로고    scopus 로고
    • Archaeological skeletons support a northwest european origin for paget's disease of bone
    • Mays S (2010) Archaeological skeletons support a northwest European origin for Paget's disease of bone. J Bone Miner Res 25:1839-1841
    • (2010) J Bone Miner Res , vol.25 , pp. 1839-1841
    • Mays, S.1
  • 13
    • 0036861114 scopus 로고    scopus 로고
    • Paget's disease in new zealand: Evidence for declining prevalence
    • Doyle T, Gunn J, Anderson G, Gill M, Cundy T (2002) Paget's disease in New Zealand: evidence for declining prevalence. Bone 31:616-619
    • (2002) Bone , vol.31 , pp. 616-619
    • Doyle, T.1    Gunn, J.2    Anderson, G.3    Gill, M.4    Cundy, T.5
  • 14
    • 33749250010 scopus 로고    scopus 로고
    • Epidemiology of paget's disease in europe: The prevalence is decreasing
    • Poor G, Donath J, Fornet B, Cooper C (2006) Epidemiology of Paget's disease in Europe: the prevalence is decreasing. J Bone Miner Res 21:1545-1549
    • (2006) J Bone Miner Res , vol.21 , pp. 1545-1549
    • Poor, G.1    Donath, J.2    Fornet, B.3    Cooper, C.4
  • 15
    • 11944270643 scopus 로고    scopus 로고
    • Paget's disease of bone in new zealand: Continued decline in disease severity
    • Cundy HR, Gamble G, Wattie D, Rutland M, Cundy T (2004) Paget's disease of bone in New Zealand: continued decline in disease severity. Calcif Tissue Int 75:358-364
    • (2004) Calcif Tissue Int , vol.75 , pp. 358-364
    • Cundy, H.R.1    Gamble, G.2    Wattie, D.3    Rutland, M.4    Cundy, T.5
  • 19
    • 0033827275 scopus 로고    scopus 로고
    • Long-term trends in the incidence of paget's disease of bone
    • Tiegs RD, Lohse CM, Wollan PC, Melton LJ (2000) Long-term trends in the incidence of Paget's disease of bone. Bone 27: 423-427
    • (2000) Bone , vol.27 , pp. 423-427
    • Tiegs, R.D.1    Lohse, C.M.2    Wollan, P.C.3    Melton, L.J.4
  • 20
    • 0028221605 scopus 로고
    • Epidemiological aspects of paget's disease: Family history and relationship to other medical conditions
    • Siris ES (1994) Epidemiological aspects of Paget's disease: family history and relationship to other medical conditions. Semin Arthritis Rheum 23:222-225
    • (1994) Semin Arthritis Rheum , vol.23 , pp. 222-225
    • Siris, E.S.1
  • 21
    • 0016264708 scopus 로고
    • Distribution of paget's diease in england, wales and scotland and a possible relationship with vitaminddeficiency in childhood
    • Barker DJ, Gardner MJ (1974) Distribution of Paget's diease in England, Wales and Scotland and a possible relationship with vitaminDdeficiency in childhood. Br J Prev Soc Med 28:226-232
    • (1974) Br J Prev Soc Med , vol.28 , pp. 226-232
    • Barker, D.J.1    Gardner, M.J.2
  • 22
    • 0036755763 scopus 로고    scopus 로고
    • Paget's disease of bone in lancashire and arsenic pesticide in cotton mill wastewater: A speculative hypothesis
    • Lever JH (2002) Paget's disease of bone in Lancashire and arsenic pesticide in cotton mill wastewater: a speculative hypothesis. Bone 31:434-436
    • (2002) Bone , vol.31 , pp. 434-436
    • Lever, J.H.1
  • 23
    • 0018774333 scopus 로고
    • Billiard-player's fingers: An unusual case of paget's disease of bone
    • Solomon LR (1979) Billiard-player's fingers: an unusual case of Paget's disease of bone. Br Med J 1:931
    • (1979) Br Med J , vol.1 , pp. 931
    • Solomon, L.R.1
  • 24
    • 0018782027 scopus 로고
    • Paget's disease in a treadle machine operator [letter]
    • Gasper TM (1979) Paget's disease in a treadle machine operator [letter]. Br Med J 1:1217-1218
    • (1979) Br Med J , vol.1 , pp. 1217-1218
    • Gasper, T.M.1
  • 28
    • 0021337486 scopus 로고
    • Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with paget's disease of bone
    • Mills BG, Singer FR, Weiner LP, Suffin SC, Stabile E, Holst P (1984) Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin Orthop Relat Res 183:303-311
    • (1984) Clin Orthop Relat Res , vol.183 , pp. 303-311
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Suffin, S.C.4    Stabile, E.5    Holst, P.6
  • 29
    • 0022414463 scopus 로고
    • Past pets and paget's disease
    • O'Driscoll JB, Anderson DC (1985) Past pets and Paget's disease. Lancet 2:919-921
    • (1985) Lancet , vol.2 , pp. 919-921
    • O'Driscoll, J.B.1    Anderson, D.C.2
  • 30
    • 34249704670 scopus 로고    scopus 로고
    • Multicenter blinded analysis of rt-pcr detection methods for paramyxoviruses in relation to paget's disease of bone
    • Ralston SH, Afzal MA, Helfrich MH, Fraser WD, Gallagher JA, Mee A, Rima B (2007) Multicenter blinded analysis of RT-PCR detection methods for paramyxoviruses in relation to Paget's disease of bone. J Bone Miner Res 22:569-577
    • (2007) J Bone Miner Res , vol.22 , pp. 569-577
    • Ralston, S.H.1    Afzal, M.A.2    Helfrich, M.H.3    Fraser, W.D.4    Gallagher, J.A.5    Mee, A.6    Rima, B.7
  • 35
    • 0023787752 scopus 로고
    • Osteoclasts in human osteopetrosis contain viral-nucleocapsid-like nuclear inclusions
    • Mills BG, Yabe H, Singer FR (1988) Osteoclasts in human osteopetrosis contain viral-nucleocapsid-like nuclear inclusions. J Bone Miner Res 3:101-106
    • (1988) J Bone Miner Res , vol.3 , pp. 101-106
    • Mills, B.G.1    Yabe, H.2    Singer, F.R.3
  • 36
    • 0026488211 scopus 로고
    • Paramyxovirus-like nuclear inclusions identical to those of paget's disease of bone detected in giant cells of primary oxalosis
    • Bianco P, Silvestrini G, Ballanti P, Bonucci E (1992) Paramyxovirus-like nuclear inclusions identical to those of Paget's disease of bone detected in giant cells of primary oxalosis. Virchows Arch Pathol Anat Histopathol 421:427-433
    • (1992) Virchows Arch Pathol Anat Histopathol , vol.421 , pp. 427-433
    • Bianco, P.1    Silvestrini, G.2    Ballanti, P.3    Bonucci, E.4
  • 38
    • 0033037919 scopus 로고    scopus 로고
    • Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
    • Sieradzan KA, Mechan AO, Jones L, Wanker EE, Nukina N, Mann DM (1999) Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein. Exp Neurol 156:92-99
    • (1999) Exp Neurol , vol.156 , pp. 92-99
    • Sieradzan, K.A.1    Mechan, A.O.2    Jones, L.3    Wanker, E.E.4    Nukina, N.5    Mann, D.M.6
  • 40
    • 0033827136 scopus 로고    scopus 로고
    • Osteoclast differentiation from circulating mononuclear precursors in paget's disease is hypersensitive to 1,25-dihydroxyvitamin d3 and rankl
    • Neale SD, Smith R, Wass JA, Athanasou NA (2000) Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D3 and RANKL. Bone 27:409-416
    • (2000) Bone , vol.27 , pp. 409-416
    • Neale, S.D.1    Smith, R.2    Wass, J.A.3    Athanasou, N.A.4
  • 42
    • 0030895661 scopus 로고    scopus 로고
    • Cellular immunity aspects in elderly subjects with paget's disease of bone
    • Natale VM, Filho WJ, Duarte AJ (1997) Cellular immunity aspects in elderly subjects with Paget's disease of bone. Calcif Tissue Int 60:410-414
    • (1997) Calcif Tissue Int , vol.60 , pp. 410-414
    • Natale, V.M.1    Filho, W.J.2    Duarte, A.J.3
  • 43
    • 0028358344 scopus 로고
    • Cytokine and growth factor expression in paget's disease: Analysis by reverse-transcription/polymerase chain reaction
    • Ralston SH, Hoey SA, Gallacher SJ, Adamson BB, Boyle IT (1994) Cytokine and growth factor expression in Paget's disease: analysis by reverse-transcription/polymerase chain reaction. Br J Rheumatol 33:620-625
    • (1994) Br J Rheumatol , vol.33 , pp. 620-625
    • Ralston, S.H.1    Hoey, S.A.2    Gallacher, S.J.3    Adamson, B.B.4    Boyle, I.T.5
  • 44
    • 38549119003 scopus 로고    scopus 로고
    • Gene expression profiling in paget's disease of bone: Upregulation of interferon signaling pathways in pagetic monocytes and lymphocytes
    • Nagy ZB, Gergely P, Donath J, Borgulya G, Csanad M, Poor G (2008) Gene expression profiling in Paget's disease of bone: upregulation of interferon signaling pathways in pagetic monocytes and lymphocytes. J Bone Miner Res 23:253-259
    • (2008) J Bone Miner Res , vol.23 , pp. 253-259
    • Nagy, Z.B.1    Gergely, P.2    Donath, J.3    Borgulya, G.4    Csanad, M.5    Poor, G.6
  • 46
    • 0034613188 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of nf-kappa b ligand (rankl)
    • Matsumoto M, Sudo T, Saito T, Osada H, Tsujimoto M (2000) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J Biol Chem 275:31155-31161
    • (2000) J Biol Chem , vol.275 , pp. 31155-31161
    • Matsumoto, M.1    Sudo, T.2    Saito, T.3    Osada, H.4    Tsujimoto, M.5
  • 47
    • 69449101599 scopus 로고    scopus 로고
    • Fgf-2 stimulation of rank ligand expression in paget's disease of bone
    • Sundaram K, Senn J, Yuvaraj S, Rao DS, Reddy SV (2009) FGF-2 stimulation of RANK ligand expression in Paget's disease of bone. Mol Endocrinol 23:1445-1454
    • (2009) Mol Endocrinol , vol.23 , pp. 1445-1454
    • Sundaram, K.1    Senn, J.2    Yuvaraj, S.3    Rao, D.S.4    Reddy, S.V.5
  • 48
    • 0036224335 scopus 로고    scopus 로고
    • The influence of serum cytokines and growth factors on osteoclast formation in paget's disease
    • Neale SD, Schulze E, Smith R, Athanasou NA (2002) The influence of serum cytokines and growth factors on osteoclast formation in Paget's disease. QJM 95:233-240
    • (2002) QJM , vol.95 , pp. 233-240
    • Neale, S.D.1    Schulze, E.2    Smith, R.3    Athanasou, N.A.4
  • 50
    • 74949141076 scopus 로고    scopus 로고
    • Dickkopf-1 as a potential therapeutic target in paget's disease of bone
    • McCarthy HS, Marshall MJ (2010) Dickkopf-1 as a potential therapeutic target in Paget's disease of bone. Expert Opin Ther Targets 14:221-230
    • (2010) Expert Opin Ther Targets , vol.14 , pp. 221-230
    • McCarthy, H.S.1    Marshall, M.J.2
  • 52
    • 33745510646 scopus 로고    scopus 로고
    • A novel mutation (k378x) in the sequestosome 1 gene associated with increased nf-kappab signaling and paget's disease of bone with a severe phenotype
    • Rea SL, Walsh JP, Ward L, Yip K, Ward BK, Kent GN, Steer JH, Xu J, Ratajczak T (2006) A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype. J Bone Miner Res 21:1136-1145
    • (2006) J Bone Miner Res , vol.21 , pp. 1136-1145
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3    Yip, K.4    Ward, B.K.5    Kent, G.N.6    Steer, J.H.7    Xu, J.8    Ratajczak, T.9
  • 54
    • 80054885414 scopus 로고    scopus 로고
    • Mutant p62p392l stimulation of osteoclast differentiation in paget's disease of bone
    • Sundaram K, Shanmugarajan S, Rao DS, Reddy SV (2011) Mutant p62P392L stimulation of osteoclast differentiation in Paget's disease of bone. Endocrinology 152:4180-4189
    • (2011) Endocrinology , vol.152 , pp. 4180-4189
    • Sundaram, K.1    Shanmugarajan, S.2    Rao, D.S.3    Reddy, S.V.4
  • 55
    • 0027484047 scopus 로고
    • Abnormalities in osteoclast precursors and marrow accessory cells in paget's disease
    • Demulder A, Takahashi S, Singer FR, Hosking DJ, Roodman GD (1993) Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease. Endocrinology 133:1978-1982
    • (1993) Endocrinology , vol.133 , pp. 1978-1982
    • Demulder, A.1    Takahashi, S.2    Singer, F.R.3    Hosking, D.J.4    Roodman, G.D.5
  • 56
    • 33645987648 scopus 로고    scopus 로고
    • Bone stromal cells in pagetic bone and paget's sarcoma express rankl and support human osteoclast formation
    • Sun SG, Lau YS, Itonaga I, Sabokbar A, Athanasou NA (2006) Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation. J Pathol 209:114-120
    • (2006) J Pathol , vol.209 , pp. 114-120
    • Sun, S.G.1    Lau, Y.S.2    Itonaga, I.3    Sabokbar, A.4    Athanasou, N.A.5
  • 59
    • 34247861003 scopus 로고    scopus 로고
    • Sequestosome 1: Mutation frequencies, haplotypes, and phenotypes in familial paget's disease of bone
    • Morissette J, Laurin N, Brown JP (2006) Sequestosome 1: mutation frequencies, haplotypes, and phenotypes in familial Paget's disease of bone. J Bone Miner Res 21(Suppl 2):38-44
    • (2006) J Bone Miner Res , vol.21 , Issue.SUPPL. 2 , pp. 38-44
    • Morissette, J.1    Laurin, N.2    Brown, J.P.3
  • 60
    • 2342493320 scopus 로고    scopus 로고
    • Familial paget's disease in the netherlands: Occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations
    • Eekhoff EW, Karperien M, Houtsma D, Zwinderman AH, Dragoiescu C, Kneppers AL, Papapoulos SE (2004) Familial Paget's disease in the Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum 50:1650-1654
    • (2004) Arthritis Rheum , vol.50 , pp. 1650-1654
    • Eekhoff, E.W.1    Karperien, M.2    Houtsma, D.3    Zwinderman, A.H.4    Dragoiescu, C.5    Kneppers, A.L.6    Papapoulos, S.E.7
  • 65
    • 0036094026 scopus 로고    scopus 로고
    • Recurrent mutation of the gene encoding sequestosome 1 (sqstm1/p62) in paget disease of bone
    • Laurin N, Brown JP, Morissette J, Raymond V (2002) Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Am J Hum Genet 70:1582-1588
    • (2002) Am J Hum Genet , vol.70 , pp. 1582-1588
    • Laurin, N.1    Brown, J.P.2    Morissette, J.3    Raymond, V.4
  • 69
    • 11944268320 scopus 로고    scopus 로고
    • Sqstm1 and paget's disease of bone
    • Layfield R, Hocking LJ (2004) SQSTM1 and Paget's disease of bone. Calcif Tissue Int 75:347-357
    • (2004) Calcif Tissue Int , vol.75 , pp. 347-357
    • Layfield, R.1    Hocking, L.J.2
  • 70
    • 38949162988 scopus 로고    scopus 로고
    • Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy
    • Tan JM, Wong ES, Dawson VL, Dawson TM, Lim KL (2007) Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy. Autophagy 4:251-253
    • (2007) Autophagy , vol.4 , pp. 251-253
    • Tan, J.M.1    Wong, E.S.2    Dawson, V.L.3    Dawson, T.M.4    Lim, K.L.5
  • 72
    • 27944504351 scopus 로고    scopus 로고
    • P62/sqstm1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171:603-614
    • (2005) J Cell Biol , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6    Stenmark, H.7    Johansen, T.8
  • 75
    • 0027473329 scopus 로고
    • Macrophage colonystimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors
    • Tanaka S, Takahashi N, Udagawa N, Tamura T, Akatsu T, Stanley ER, Kurokawa T, Suda T (1993) Macrophage colonystimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors. J Clin Invest 91: 257-263
    • (1993) J Clin Invest , vol.91 , pp. 257-263
    • Tanaka, S.1    Takahashi, N.2    Udagawa, N.3    Tamura, T.4    Akatsu, T.5    Stanley, E.R.6    Kurokawa, T.7    Suda, T.8
  • 77
    • 0037195141 scopus 로고    scopus 로고
    • The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat csf1 gene: Evidence of a crucial role for csf-1 in osteoclastogenesis and endochondral ossification
    • Van Wesenbeeck L, Odgren PR, MacKay CA, D'Angelo M, Safadi FF, Popoff SN, Van Hul W, Marks SC Jr. (2002) The osteopetrotic mutation toothless (tl) is a loss-of-function frameshift mutation in the rat Csf1 gene: evidence of a crucial role for CSF-1 in osteoclastogenesis and endochondral ossification. Proc Natl Acad Sci USA 99:14303-14308
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14303-14308
    • Van Wesenbeeck, L.1    Odgren, P.R.2    MacKay, C.A.3    D'Angelo, M.4    Safadi, F.F.5    Popoff, S.N.6    Van Hul, W.7    Marks Jr., S.C.8
  • 78
    • 0028201425 scopus 로고
    • Macrophage colony-stimulating factor restores bone resorption in op/op bone in vitro in conjunction with parathyroid hormone or 1,25-dihydroxyvitamin d3
    • Morohashi T, Corboz VA, Fleisch H, Cecchini MG, Felix R (1994) Macrophage colony-stimulating factor restores bone resorption in op/op bone in vitro in conjunction with parathyroid hormone or 1,25-dihydroxyvitamin D3. J Bone Miner Res 9: 401-407
    • (1994) J Bone Miner Res , vol.9 , pp. 401-407
    • Morohashi, T.1    Corboz, V.A.2    Fleisch, H.3    Cecchini, M.G.4    Felix, R.5
  • 84
    • 0038643034 scopus 로고    scopus 로고
    • Phenotypic characterization of early onset paget's disease of bone caused by a 27 bp duplication in the tnfrsf11a gene
    • Nakatsuka K, Nishizawa Y, Ralston SH (2003) Phenotypic characterization of early onset Paget's disease of bone caused by a 27 bp duplication in the TNFRSF11A gene. J Bone Miner Res 18:1381-1385
    • (2003) J Bone Miner Res , vol.18 , pp. 1381-1385
    • Nakatsuka, K.1    Nishizawa, Y.2    Ralston, S.H.3
  • 85
    • 0036133351 scopus 로고    scopus 로고
    • Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in tnfrsf11a encoding rank and is allelic to familial expansile osteolysis
    • Whyte MP, Hughes AE (2002) Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis. J Bone Miner Res 17:26-29
    • (2002) J Bone Miner Res , vol.17 , pp. 26-29
    • Whyte, M.P.1    Hughes, A.E.2
  • 92
    • 34547924464 scopus 로고    scopus 로고
    • Optineurin negatively regulates tnfalpha-induced nf-kappab activation by competing with nemo for ubiquitinated rip
    • Zhu G, Wu CJ, Zhao Y, Ashwell JD (2007) Optineurin negatively regulates TNFalpha-induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP. Curr Biol 17: 1438-1443
    • (2007) Curr Biol , vol.17 , pp. 1438-1443
    • Zhu, G.1    Wu, C.J.2    Zhao, Y.3    Ashwell, J.D.4
  • 98
    • 79952325263 scopus 로고    scopus 로고
    • Optineurin is required for cyld-dependent inhibition of tnfalpha-induced nf-kappab activation
    • Nagabhushana A, Bansal M, Swarup G (2011) Optineurin is required for CYLD-dependent inhibition of TNFalpha-induced NF-kappaB activation. PLoS ONE 6:e17477
    • (2011) PLoS ONE , vol.6
    • Nagabhushana, A.1    Bansal, M.2    Swarup, G.3
  • 104
    • 0030824317 scopus 로고    scopus 로고
    • Nup93, a vertebrate homologue of yeast nic96p, forms a complex with a novel 205 kda protein and is required for correct nuclear pore assembly
    • Grandi P, Dang T, Pane N, Shevchenko A, Mann M, Forbes D, Hurt E (1997) Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205 kDa protein and is required for correct nuclear pore assembly. Mol Biol Cell 8:2017-2038
    • (1997) Mol Biol Cell , vol.8 , pp. 2017-2038
    • Grandi, P.1    Dang, T.2    Pane, N.3    Shevchenko, A.4    Mann, M.5    Forbes, D.6    Hurt, E.7
  • 105
    • 0037169341 scopus 로고    scopus 로고
    • The role of pml in tumor suppression
    • Salomoni P, Pandolfi PP (2002) The role of PML in tumor suppression. Cell 108:165-170
    • (2002) Cell , vol.108 , pp. 165-170
    • Salomoni, P.1    Pandolfi, P.P.2
  • 106
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • Watts GD, Wymer J, Kovach MJ, Mehta SG, Mumm S, Darvish D, Pestronk A, Whyte MP, Kimonis VE (2004) Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat Genet 36:377-381
    • (2004) Nat Genet , vol.36 , pp. 377-381
    • Watts, G.D.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6    Pestronk, A.7    Whyte, M.P.8    Kimonis, V.E.9
  • 108
    • 0034532113 scopus 로고    scopus 로고
    • Clinical and molecular studies in a unique family with autosomal dominant limb-girdle muscular dystrophy and paget disease of bone
    • Kimonis VE, Kovach MJ, Waggoner B, Leal S, Salam A, Rimer L, Davis K, Khardori R, Gelber D (2000) Clinical and molecular studies in a unique family with autosomal dominant limb-girdle muscular dystrophy and Paget disease of bone. Genet Med 2:232-241
    • (2000) Genet Med , vol.2 , pp. 232-241
    • Kimonis, V.E.1    Kovach, M.J.2    Waggoner, B.3    Leal, S.4    Salam, A.5    Rimer, L.6    Davis, K.7    Khardori, R.8    Gelber, D.9
  • 109
    • 84856474838 scopus 로고    scopus 로고
    • Emerging functions of the vcp/p97 aaa-atpase in the ubiquitin system
    • Meyer H, Bug M, Bremer S (2012) Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat Cell Biol 14:117-123
    • (2012) Nat Cell Biol , vol.14 , pp. 117-123
    • Meyer, H.1    Bug, M.2    Bremer, S.3
  • 110
    • 11844263929 scopus 로고    scopus 로고
    • A series of ubiquitin binding factors connects cdc48/p97 to substrate multiubiquitylation and proteasomal targeting
    • Richly H, Rape M, Braun S, Rumpf S, Hoege C, Jentsch S (2005) A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting. Cell 120:73-84
    • (2005) Cell , vol.120 , pp. 73-84
    • Richly, H.1    Rape, M.2    Braun, S.3    Rumpf, S.4    Hoege, C.5    Jentsch, S.6
  • 111
    • 2342511583 scopus 로고    scopus 로고
    • The ubx2 and ubx3 cofactors direct cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes
    • Hartmann-Petersen R, Wallace M, Hofmann K, Koch G, Johnsen AH, Hendil KB, Gordon C (2004) The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes. Curr Biol 14:824-828
    • (2004) Curr Biol , vol.14 , pp. 824-828
    • Hartmann-Petersen, R.1    Wallace, M.2    Hofmann, K.3    Koch, G.4    Johnsen, A.H.5    Hendil, K.B.6    Gordon, C.7
  • 112
    • 8544263881 scopus 로고    scopus 로고
    • Aaa atpase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation
    • Zhong X, Shen Y, Ballar P, Apostolou A, Agami R, Fang S (2004) AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation. J Biol Chem 279:45676-45684
    • (2004) J Biol Chem , vol.279 , pp. 45676-45684
    • Zhong, X.1    Shen, Y.2    Ballar, P.3    Apostolou, A.4    Agami, R.5    Fang, S.6
  • 113
    • 77952533111 scopus 로고    scopus 로고
    • Vcp/p97 is essential formaturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause ibmpfd
    • Tresse E, Salomons FA, Vesa J, Bott LC, Kimonis V, Yao TP, DantumaNP, Taylor JP (2010)VCP/p97 is essential formaturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy 6:217-227
    • (2010) Autophagy , vol.6 , pp. 217-227
    • Tresse, E.1    Salomons, F.A.2    Vesa, J.3    Bott, L.C.4    Kimonis, V.5    Yao, T.P.6    Dantuma, N.P.7    Taylor, J.P.8
  • 114
    • 34447093377 scopus 로고    scopus 로고
    • Transgenic expression of inclusion body myopathy associated mutant p97/vcp causes weakness and ubiquitinated protein inclusions in mice
    • Weihl CC, Miller SE, Hanson PI, Pestronk A (2007) Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice. Hum Mol Genet 16:919-928
    • (2007) Hum Mol Genet , vol.16 , pp. 919-928
    • Weihl, C.C.1    Miller, S.E.2    Hanson, P.I.3    Pestronk, A.4
  • 116
    • 31144470450 scopus 로고    scopus 로고
    • Inclusion body myopathy-associated mutations in p97/vcp impair endoplasmic reticulum-associated degradation
    • Weihl CC, Dalal S, Pestronk A, Hanson PI (2006) Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation. Hum Mol Genet 15: 189-199
    • (2006) Hum Mol Genet , vol.15 , pp. 189-199
    • Weihl, C.C.1    Dalal, S.2    Pestronk, A.3    Hanson, P.I.4
  • 121
    • 0027525968 scopus 로고
    • Paget's disease of bone
    • Ralston SH (1993) Paget's disease of bone. Br Med J 306: 332-333
    • (1993) Br Med J , vol.306 , pp. 332-333
    • Ralston, S.H.1
  • 124
    • 77749301510 scopus 로고    scopus 로고
    • Recent advances in understanding the molecular basis of paget disease of bone
    • Goode A, Layfield R (2010) Recent advances in understanding the molecular basis of Paget disease of bone. J Clin Pathol 63:199-203
    • (2010) J Clin Pathol , vol.63 , pp. 199-203
    • Goode, A.1    Layfield, R.2
  • 128
    • 67650234499 scopus 로고    scopus 로고
    • Nbr1 cooperates with p62 in selective autophagy of ubiquitinated targets
    • Kirkin V, Lamark T, Johansen T, Dikic I (2009) NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets. Autophagy 5:732-733
    • (2009) Autophagy , vol.5 , pp. 732-733
    • Kirkin, V.1    Lamark, T.2    Johansen, T.3    Dikic, I.4
  • 132
    • 0017114175 scopus 로고
    • Nuclear inclusions in paget's disease of bone
    • Mills BG, Singer FR (1976) Nuclear inclusions in Paget's disease of bone. Science 194:201-202
    • (1976) Science , vol.194 , pp. 201-202
    • Mills, B.G.1    Singer, F.R.2
  • 133
    • 0028283338 scopus 로고
    • Multinucleated cells formed in vitro from paget's bone marrow express viral antigens
    • Mills BG, Frausto A, Singer FR, Ohsaki Y, Demulder A, Roodman GD (1994) Multinucleated cells formed in vitro from Paget's bone marrow express viral antigens. Bone 15:443-448
    • (1994) Bone , vol.15 , pp. 443-448
    • Mills, B.G.1    Frausto, A.2    Singer, F.R.3    Ohsaki, Y.4    Demulder, A.5    Roodman, G.D.6
  • 135
    • 0019508461 scopus 로고
    • Immunohistological demonstration of respiratory syncytial virus antigens in paget's disease of bone
    • Mills BG, Singer FR, Weiner LP, Holst PA (1981) Immunohistological demonstration of respiratory syncytial virus antigens in Paget's disease of bone. Proc Natl Acad Sci USA 78:1209-1212
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 1209-1212
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Holst, P.A.4
  • 137
    • 0025282325 scopus 로고
    • Paget's disease of bone and previous pet ownership in the united states: Dogs exonerated
    • Siris ES, Kelsey JL, Flaster E, Parker S (1990) Paget's disease of bone and previous pet ownership in the United States: dogs exonerated. Int J Epidemiol 19:455-458
    • (1990) Int J Epidemiol , vol.19 , pp. 455-458
    • Siris, E.S.1    Kelsey, J.L.2    Flaster, E.3    Parker, S.4
  • 138
    • 0025742622 scopus 로고
    • Canine distemper virus localised in bone cells of patients with paget's disease
    • Gordon MT, Anderson DC, Sharpe PT (1991) Canine distemper virus localised in bone cells of patients with Paget's disease. Bone 12:195-201
    • (1991) Bone , vol.12 , pp. 195-201
    • Gordon, M.T.1    Anderson, D.C.2    Sharpe, P.T.3
  • 139
    • 0032146198 scopus 로고    scopus 로고
    • Detection of canine distemper virus in 100% of paget's disease samples by in situ-reverse transcriptase polymerase chain reaction
    • Mee AP, Dixon JA, Hoyland JA, Davies M, Selby PL, Mawer EB (1998) Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase polymerase chain reaction. Bone 23:171-175
    • (1998) Bone , vol.23 , pp. 171-175
    • Mee, A.P.1    Dixon, J.A.2    Hoyland, J.A.3    Davies, M.4    Selby, P.L.5    Mawer, E.B.6
  • 140
  • 141
    • 0022548561 scopus 로고
    • Measles virus rna detected in paget's disease bone tissue by in situ hybridization
    • Basle MF, Fournier JG, Rozenblatt S, Rebel A, Bouteille M (1986) Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization. J Gen Virol 67(Pt 5):907-913
    • (1986) J Gen Virol , vol.67 , Issue.PART 5 , pp. 907-913
    • Basle, M.F.1    Fournier, J.G.2    Rozenblatt, S.3    Rebel, A.4    Bouteille, M.5
  • 142
    • 0032883330 scopus 로고    scopus 로고
    • Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with paget's disease of bone
    • Reddy SV, Menaa C, Singer FR, Cundy T, Cornish J, Whyte MP, Roodman GD (1999) Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone. Exp Hematol 27:1528-1532
    • (1999) Exp Hematol , vol.27 , pp. 1528-1532
    • Reddy, S.V.1    Menaa, C.2    Singer, F.R.3    Cundy, T.4    Cornish, J.5    Whyte, M.P.6    Roodman, G.D.7
  • 143
    • 0025720792 scopus 로고
    • Failure to detect paramyxovirus sequences in paget's disease of bone using the polymerase chain reaction
    • Ralston SH, DiGiovine FS, Gallacher SJ, Boyle IT, Duff GW (1991) Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction. J Bone Miner Res 6:1243-1248
    • (1991) J Bone Miner Res , vol.6 , pp. 1243-1248
    • Ralston, S.H.1    DiGiovine, F.S.2    Gallacher, S.J.3    Boyle, I.T.4    Duff, G.W.5
  • 145
    • 0033831096 scopus 로고    scopus 로고
    • Absence of measles virus and canine distemper virus transcripts in longterm bone marrow cultures from patients with paget's disease of bone
    • Ooi CG, Walsh CA, Gallagher JA, Fraser WD (2000) Absence of measles virus and canine distemper virus transcripts in longterm bone marrow cultures from patients with Paget's disease of bone. Bone 27:417-421
    • (2000) Bone , vol.27 , pp. 417-421
    • Ooi, C.G.1    Walsh, C.A.2    Gallagher, J.A.3    Fraser, W.D.4
  • 146
    • 0026956388 scopus 로고
    • In situ analysis of paget's disease of bone for measlesspecific pcr-amplified cdna
    • Nuovo MA, Nuovo GJ, MacConnell P, Forde A, Steiner GC (1992) In situ analysis of Paget's disease of bone for measlesspecific PCR-amplified cDNA. Diagn Mol Pathol 1:256-265
    • (1992) Diagn Mol Pathol , vol.1 , pp. 256-265
    • Nuovo, M.A.1    Nuovo, G.J.2    MacConnell, P.3    Forde, A.4    Steiner, G.C.5
  • 149
    • 0029116734 scopus 로고
    • Generation of multinucleated osteoclast-like cells from canine bone marrow: Effects of canine distemper virus
    • Mee AP, May C, Bennett D, Sharpe PT (1995) Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus. Bone 17:47-55
    • (1995) Bone , vol.17 , pp. 47-55
    • Mee, A.P.1    May, C.2    Bennett, D.3    Sharpe, P.T.4
  • 150
    • 0034989963 scopus 로고    scopus 로고
    • Osteoclasts formed by measles virus-infected osteoclast precursors from hcd46 transgenic mice express characteristics of pagetic osteoclasts
    • Reddy SV, Kurihara N, Menaa C, Landucci G, Forthal D, Koop BA, Windle JJ, Roodman GD (2001) Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts. Endocrinology 142:2898-2905
    • (2001) Endocrinology , vol.142 , pp. 2898-2905
    • Reddy, S.V.1    Kurihara, N.2    Menaa, C.3    Landucci, G.4    Forthal, D.5    Koop, B.A.6    Windle, J.J.7    Roodman, G.D.8
  • 151
    • 0034104393 scopus 로고    scopus 로고
    • Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype
    • Kurihara N, Reddy SV, Menaa C, Anderson D, Roodman GD (2000) Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. J Clin Invest 105:607-614
    • (2000) J Clin Invest , vol.105 , pp. 607-614
    • Kurihara, N.1    Reddy, S.V.2    Menaa, C.3    Anderson, D.4    Roodman, G.D.5
  • 154
    • 0027359196 scopus 로고
    • Mice transgenic for htlv-i ltr-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover
    • Ruddle NH, Li CB, Horne WC, Santiago P, Troiano N, Jay G, Horowitz Baron R (1993) Mice transgenic for HTLV-I LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover. Virology 197:196-204
    • (1993) Virology , vol.197 , pp. 196-204
    • Ruddle, N.H.1    Li, C.B.2    Horne, W.C.3    Santiago, P.4    Troiano, N.5    Jay, G.6    Horowitz Baron, R.7
  • 156
    • 77952486387 scopus 로고    scopus 로고
    • Transgenic mice expressing mutant forms vcp/p97 recapitulate the full spectrum of ibmpfd including degeneration in muscle, brain and bone
    • Custer SK, Neumann M, Lu H, Wright AC, Taylor JP (2010) Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone. Hum Mol Genet 19:1741-1755
    • (2010) Hum Mol Genet , vol.19 , pp. 1741-1755
    • Custer, S.K.1    Neumann, M.2    Lu, H.3    Wright, A.C.4    Taylor, J.P.5
  • 157
    • 70349101680 scopus 로고    scopus 로고
    • Sequestosome 1 mutations in paget's disease of bone in australia: Prevalence, genotype/phenotype correlation and a novel non-uba domain mutation (p364s) associated with increased nf-kappab signaling without loss of ubiquitin-binding
    • Rea SL, Walsh JP, Ward L, Magno AL, Ward BK, Shaw B, Layfield R, Kent GN, Xu J, Ratajczak T (2009) Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin-binding. J Bone Miner Res 24: 1216-1223
    • (2009) J Bone Miner Res , vol.24 , pp. 1216-1223
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3    Magno, A.L.4    Ward, B.K.5    Shaw, B.6    Layfield, R.7    Kent, G.N.8    Xu, J.9    Ratajczak, T.10


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