-
1
-
-
56049128160
-
Therapeutic potential of HMGB1- targeting agents in sepsis
-
Wang H, Zhu S, Zhou R, et al. Therapeutic potential of HMGB1- targeting agents in sepsis. Expert Rev Mol Med 2008;10:e32
-
(2008)
Expert Rev Mol Med
, vol.10
-
-
Wang, H.1
Zhu, S.2
Zhou, R.3
-
2
-
-
84874424895
-
Sepsis definitions: Time for change
-
Vincent JL, Opal SM, Marshall JC, et al. Sepsis definitions: time for change. Lancet 2013;381: 774-5 • These authors proposed a new definition for sepsis.
-
(2013)
Lancet
, vol.381
, pp. 774-775
-
-
Vincent, J.L.1
Opal, S.M.2
Marshall, J.C.3
-
3
-
-
37549020378
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock
-
Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock. Crit Care Med 2008;36: 296-327
-
(2008)
Crit Care Med
, vol.36
, pp. 296-327
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
-
4
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29: 1303-10
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
-
5
-
-
30044447736
-
Immune cell migration in inflammation: Present and future therapeutic targets
-
Luster AD, Alon R, von Andrian UH. Immune cell migration in inflammation: present and future therapeutic targets. Nat Immunol 2005;6: 1182-90
-
(2005)
Nat Immunol
, vol.6
, pp. 1182-1190
-
-
Luster, A.D.1
Alon, R.2
Von Andrian, U.H.3
-
6
-
-
0035069871
-
Immunomodulatory approaches to augment phagocytemediated host defense for treatment of infectious diseases
-
Liles WC. Immunomodulatory approaches to augment phagocytemediated host defense for treatment of infectious diseases. Semin Respir Infect 2001;16: 11-17
-
(2001)
Semin Respir Infect
, vol.16
, pp. 11-17
-
-
Liles, W.C.1
-
7
-
-
77749242763
-
TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism
-
Ha T, Lu C, Liu L, et al. TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism. Am J Physiol Heart Circ Physiol 2010;298:H984-91
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Ha, T.1
Lu, C.2
Liu, L.3
-
8
-
-
84864284372
-
Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis
-
Gao M, Ha T, Zhang X, et al. Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis. Crit Care Med 2012;40: 2390-9
-
(2012)
Crit Care Med
, vol.40
, pp. 2390-2399
-
-
Gao, M.1
Ha, T.2
Zhang, X.3
-
9
-
-
0033618562
-
Host defense mechanisms triggered by microbial lipoproteins through tolllike receptors
-
Brightbill HD, Libraty DH, Krutzik SR, et al. Host defense mechanisms triggered by microbial lipoproteins through tolllike receptors. Science 1999;285: 732-6
-
(1999)
Science
, vol.285
, pp. 732-736
-
-
Brightbill, H.D.1
Libraty, D.H.2
Krutzik, S.R.3
-
10
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282: 2085-8
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
11
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000;408: 740-5
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
12
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4: 499-511
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
13
-
-
0033823676
-
Chemokines in inflammation and immunity
-
Baggiolini M, Loetscher P. Chemokines in inflammation and immunity. Immunol Today 2000;21: 418-20
-
(2000)
Immunol Today
, vol.21
, pp. 418-420
-
-
Baggiolini, M.1
Loetscher, P.2
-
14
-
-
0035019373
-
IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line
-
Chan ED, Riches DW. IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line. Am J Physiol Cell Physiol 2001;280:C441-50
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Chan, E.D.1
Riches, D.W.2
-
15
-
-
0028597036
-
Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia
-
Wizemann TM, Gardner CR, Laskin JD, et al. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia. J Leukoc Biol 1994;56: 759-68
-
(1994)
J Leukoc Biol
, vol.56
, pp. 759-768
-
-
Wizemann, T.M.1
Gardner, C.R.2
Laskin, J.D.3
-
16
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang H, Bloom O, Zhang M, et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999;285: 248-51 • These authors made the seminal discovery on the important role of extracellular HMG-1 (now called HMGB1) as a late mediator of lethal systemic inflammation.
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
-
17
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
-
Tracey KJ, Fong Y, Hesse DG, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987;330: 662-4 • These authors first reported a pathogenic role of proinflammatory cytokine in the pathogenesis of lethal infection.
-
(1987)
Nature
, vol.330
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
-
18
-
-
21744439466
-
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis
-
Chen G, Li J, Qiang X, et al. Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis. J Lipid Res 2005;46: 623-7
-
(2005)
J Lipid Res
, vol.46
, pp. 623-627
-
-
Chen, G.1
Li, J.2
Qiang, X.3
-
19
-
-
0142137129
-
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
-
Bonaldi T, Talamo F, Scaffidi P, et al. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003;22: 5551-60
-
(2003)
EMBO J
, vol.22
, pp. 5551-5560
-
-
Bonaldi, T.1
Talamo, F.2
Scaffidi, P.3
-
20
-
-
0037167502
-
At the crossroads of necrosis and apoptosis: Signaling to multiple cellular targets by HMGB1
-
Bustin M. At the crossroads of necrosis and apoptosis: signaling to multiple cellular targets by HMGB1. Sci STKE 2002;2002:E39
-
(2002)
Sci STKE
, vol.2002
-
-
Bustin, M.1
-
21
-
-
34250837518
-
A novel role for HMGB1 in TLR9- mediated inflammatory responses to CpG-DNA
-
Ivanov S, Dragoi AM, Wang X, et al. A novel role for HMGB1 in TLR9- mediated inflammatory responses to CpG-DNA. Blood 2007;110: 1970-81
-
(2007)
Blood
, vol.110
, pp. 1970-1981
-
-
Ivanov, S.1
Dragoi, A.M.2
Wang, X.3
-
22
-
-
84865511926
-
Novel role of PKR in inflammasome activation and HMGB1 release
-
Lu B, Nakamura T, Inouye K, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012;488: 670-4 • These authors made a breakthrough progress in uncovering the molecular mechanisms underlying the regulation of HMGB1 release.
-
(2012)
Nature
, vol.488
, pp. 670-674
-
-
Lu, B.1
Nakamura, T.2
Inouye, K.3
-
23
-
-
0141830087
-
IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism
-
Rendon-Mitchell B, Ochani M, Li J, et al. IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism. J Immunol 2003;170: 3890-7 • These authors first reported the important role of early cytokines in stimulating HMGB1 release.
-
(2003)
J Immunol
, vol.170
, pp. 3890-3897
-
-
Rendon-Mitchell, B.1
Ochani, M.2
Li, J.3
-
24
-
-
0036775236
-
The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesiclemediated secretory pathway
-
Gardella S, Andrei C, Ferrera D, et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesiclemediated secretory pathway. EMBO Rep 2002;3: 955-1001
-
(2002)
EMBO Rep
, vol.3
, pp. 955-1001
-
-
Gardella, S.1
Andrei, C.2
Ferrera, D.3
-
25
-
-
77958125448
-
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
-
Lamkanfi M, Sarkar A, Vande WL, et al. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J Immunol 2010;185: 4385-92 • These authors first reported the important role of inflammasome in the regulation of endotoxin-induced HMGB1 release.
-
(2010)
J Immunol
, vol.185
, pp. 4385-4392
-
-
Lamkanfi, M.1
Sarkar, A.2
Vande, W.L.3
-
26
-
-
0035830853
-
ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage
-
Mehta VB, Hart J, Wewers MD. ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage. J Biol Chem 2001;276: 3820-6
-
(2001)
J Biol Chem
, vol.276
, pp. 3820-3826
-
-
Mehta, V.B.1
Hart, J.2
Wewers, M.D.3
-
28
-
-
0034667943
-
ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood
-
Perregaux DG, McNiff P, Laliberte R, et al. ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood. J Immunol 2000;165: 4615-23
-
(2000)
J Immunol
, vol.165
, pp. 4615-4623
-
-
Perregaux, D.G.1
McNiff, P.2
Laliberte, R.3
-
29
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant A, Rassendren F, Kawashima E, et al. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 1996;272: 735-8
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
-
30
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002;418: 191-5 • These authors first reported that HMGB1 can be released by damaged cells.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
31
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
Tsung A, Sahai R, Tanaka H, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 2005;201: 1135-43 • These authors first reported the extracellular role of HMGB1 as a damage-associated molecular pattern (DAMP) molecule.
-
(2005)
J Exp Med
, vol.201
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
-
32
-
-
42549139329
-
Early release of HMGB-1 from neurons after the onset of brain ischemia
-
Qiu J, Nishimura M, Wang Y, et al. Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab 2008;28: 927-38
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, pp. 927-938
-
-
Qiu, J.1
Nishimura, M.2
Wang, Y.3
-
33
-
-
51649111202
-
High-mobility group box-1 in ischemiareperfusion injury of the heart
-
Andrassy M, Volz HC, Igwe JC, et al. High-mobility group box-1 in ischemiareperfusion injury of the heart. Circulation 2008;117: 3216-26
-
(2008)
Circulation
, vol.117
, pp. 3216-3226
-
-
Andrassy, M.1
Volz, H.C.2
Igwe, J.C.3
-
34
-
-
77950817867
-
Early release of high mobility group box nuclear protein 1 after severe trauma in humans: Role of injury severity and tissue hypoperfusion
-
Cohen MJ, Brohi K, Calfee CS, et al. Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. Crit Care 2009;13:R174
-
(2009)
Crit Care
, vol.13
-
-
Cohen, M.J.1
Brohi, K.2
Calfee, C.S.3
-
35
-
-
67749091145
-
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans
-
Peltz ED, Moore EE, Eckels PC, et al. HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans. Shock 2009;32: 17-22
-
(2009)
Shock
, vol.32
, pp. 17-22
-
-
Peltz, E.D.1
Moore, E.E.2
Eckels, P.C.3
-
36
-
-
77958590167
-
Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma
-
Manganelli V, Signore M, Pacini I, et al. Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma. Crit Care 2010;14:R197
-
(2010)
Crit Care
, vol.14
-
-
Manganelli, V.1
Signore, M.2
Pacini, I.3
-
37
-
-
84862203898
-
High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury
-
Zhou RR, Liu HB, Peng JP, et al. High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury. Exp Mol Pathol 2012;93: 213-19
-
(2012)
Exp Mol Pathol
, vol.93
, pp. 213-219
-
-
Zhou, R.R.1
Liu, H.B.2
Peng, J.P.3
-
38
-
-
78649535273
-
Protective effect of high-mobility group box 1 blockade on acute liver failure in rats
-
Takano K, Shinoda M, Tanabe M, et al. Protective effect of high-mobility group box 1 blockade on acute liver failure in rats. Shock 2010;34: 573-9
-
(2010)
Shock
, vol.34
, pp. 573-579
-
-
Takano, K.1
Shinoda, M.2
Tanabe, M.3
-
39
-
-
84860632523
-
High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity
-
Yang R, Zhang S, Cotoia A, et al. High mobility group B1 impairs hepatocyte regeneration in acetaminophen hepatotoxicity. BMC Gastroenterol 2012;12: 45
-
(2012)
BMC Gastroenterol
, vol.12
, pp. 45
-
-
Yang, R.1
Zhang, S.2
Cotoia, A.3
-
40
-
-
84881027019
-
Mechanistic biomarkers provide early and sensitive detection of acetaminopheninduced acute liver injury at first presentation to hospital
-
Antoine DJ, Dear JW, Lewis PS, et al. Mechanistic biomarkers provide early and sensitive detection of acetaminopheninduced acute liver injury at first presentation to hospital. Hepatology 2013;58: 777-87
-
(2013)
Hepatology
, vol.58
, pp. 777-787
-
-
Antoine, D.J.1
Dear, J.W.2
Lewis, P.S.3
-
41
-
-
84889050421
-
HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol induced parenchymal cell injury
-
Epub ahead of print
-
Seo YS, Kwon JH, Yaqoob U, et al. HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol induced parenchymal cell injury. Am J Physiol Gastrointest Liver Physiol 2013; Epub ahead of print
-
(2013)
Am J Physiol Gastrointest Liver Physiol
-
-
Seo, Y.S.1
Kwon, J.H.2
Yaqoob, U.3
-
42
-
-
79953066407
-
HMGB1 is a therapeutic target for sterile inflammation and infection
-
Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 2011;29: 139-62
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 139-162
-
-
Andersson, U.1
Tracey, K.J.2
-
43
-
-
77949409236
-
High mobility group box 1 protein as a potential drug target for infection- and injury-elicited inflammation
-
Zhu S, Li W, Ward MF, et al. High mobility group box 1 protein as a potential drug target for infection- and injury-elicited inflammation. Inflamm Allergy Drug Targets 2010;9: 60-72
-
(2010)
Inflamm Allergy Drug Targets
, vol.9
, pp. 60-72
-
-
Zhu, S.1
Li, W.2
Ward, M.F.3
-
44
-
-
84871954753
-
Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in nonhuman primates
-
Sursal T, Stearns-Kurosawa DJ, Itagaki K, et al. Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in nonhuman primates. Shock 2013;39: 55-62
-
(2013)
Shock
, vol.39
, pp. 55-62
-
-
Sursal, T.1
Stearns-Kurosawa, D.J.2
Itagaki, K.3
-
45
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, Raoof M, Chen Y, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010;464: 104-7 • These authors first reported that mtDNA functions as a DAMP molecule that orchestrate injuryelicited inflammatory responses.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
-
46
-
-
38749099112
-
Dengue virus infection induces passive release of high mobility group box 1 protein by epithelial cells
-
Chen LC, Yeh TM, Wu HN, et al. Dengue virus infection induces passive release of high mobility group box 1 protein by epithelial cells. J Infect 2008;56: 143-50 • These authors first reported the passive release of HMGB1 from virus infected cells.
-
(2008)
J Infect
, vol.56
, pp. 143-150
-
-
Chen, L.C.1
Yeh, T.M.2
Wu, H.N.3
-
47
-
-
49049090421
-
Systemic release of high mobility group box 1 protein during severe murine influenza
-
Alleva LM, Budd AC, Clark IA. Systemic release of high mobility group box 1 protein during severe murine influenza. J Immunol 2008;181: 1454-9
-
(2008)
J Immunol
, vol.181
, pp. 1454-1459
-
-
Alleva, L.M.1
Budd, A.C.2
Clark, I.A.3
-
48
-
-
84887431193
-
Vaccinia virus induces programmed necrosis in ovarian cancer cells
-
Whilding LM, Archibald KM, Kulbe H, et al. Vaccinia virus induces programmed necrosis in ovarian cancer cells. Mol Ther 2013;21(11): 2074-86
-
(2013)
Mol Ther
, vol.21
, Issue.11
, pp. 2074-2086
-
-
Whilding, L.M.1
Archibald, K.M.2
Kulbe, H.3
-
49
-
-
36949021094
-
High mobility group box 1 protein induction by Mycobacterium bovis BCG
-
Hofner P, Seprenyi G, Miczak A, et al. High mobility group box 1 protein induction by Mycobacterium bovis BCG. Mediators Inflamm 2007;2007: 53805
-
(2007)
Mediators Inflamm
, vol.2007
, pp. 53805
-
-
Hofner, P.1
Seprenyi, G.2
Miczak, A.3
-
50
-
-
43449096032
-
Mycobacterial infection induces the secretion of high-mobility group box 1 protein
-
Grover A, Taylor J, Troudt J, et al. Mycobacterial infection induces the secretion of high-mobility group box 1 protein. Cell Microbiol 2008;10: 1390-404
-
(2008)
Cell Microbiol
, vol.10
, pp. 1390-1404
-
-
Grover, A.1
Taylor, J.2
Troudt, J.3
-
51
-
-
33645473273
-
Potential role of high mobility group box 1 in viral infectious diseases
-
Wang H, Ward MF, Fan XG, et al. Potential role of high mobility group box 1 in viral infectious diseases. Viral Immunol 2006;19: 3-9
-
(2006)
Viral Immunol
, vol.19
, pp. 3-9
-
-
Wang, H.1
Ward, M.F.2
Fan, X.G.3
-
52
-
-
67650469076
-
Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers
-
Zhu S, Ashok M, Li J, et al. Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers. Mol Med 2009;15: 275-82
-
(2009)
Mol Med
, vol.15
, pp. 275-282
-
-
Zhu, S.1
Ashok, M.2
Li, J.3
-
53
-
-
0034698830
-
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
-
Andersson U, Wang H, Palmblad K, et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000;192: 565-70 • These authors first reported the proinflammatory activities of extracellular HMGB1.
-
(2000)
J Exp Med
, vol.192
, pp. 565-570
-
-
Andersson, U.1
Wang, H.2
Palmblad, K.3
-
54
-
-
33845885124
-
High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin
-
Yang D, Chen Q, Yang H, et al. High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. J Leukoc Biol 2007;81: 59-66 • These authors first reported the chemokine activities of extracellular HMGB1.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 59-66
-
-
Yang, D.1
Chen, Q.2
Yang, H.3
-
55
-
-
33845875971
-
The secretion of HMGB1 is required for the migration of maturing dendritic cells
-
Dumitriu IE, Bianchi ME, Bacci M, et al. The secretion of HMGB1 is required for the migration of maturing dendritic cells. J Leukoc Biol 2007;81: 84-91
-
(2007)
J Leukoc Biol
, vol.81
, pp. 84-91
-
-
Dumitriu, I.E.1
Bianchi, M.E.2
Bacci, M.3
-
56
-
-
33847193122
-
A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
-
Orlova VV, Choi EY, Xie C, et al. A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin. EMBO J 2007;26: 1129-39
-
(2007)
EMBO J
, vol.26
, pp. 1129-1139
-
-
Orlova, V.V.1
Choi, E.Y.2
Xie, C.3
-
57
-
-
0035911959
-
The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
-
Degryse B, Bonaldi T, Scaffidi P, et al. The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol 2001;152: 1197-206
-
(2001)
J Cell Biol
, vol.152
, pp. 1197-1206
-
-
Degryse, B.1
Bonaldi, T.2
Scaffidi, P.3
-
58
-
-
0141459720
-
The nuclear protein HMGB1, a new kind of chemokine?
-
Degryse B, de Virgilio M. The nuclear protein HMGB1, a new kind of chemokine? FEBS Lett 2003;553: 11-17
-
(2003)
FEBS Lett
, vol.553
, pp. 11-17
-
-
Degryse, B.1
De Virgilio, M.2
-
59
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
-
Tian J, Avalos AM, Mao SY, et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 2007;8: 487-96 • These authors first reported that HMGB1 amplified inflammation by facilitating innate recognition of microbial CpG-DNA.
-
(2007)
Nat Immunol
, vol.8
, pp. 487-496
-
-
Tian, J.1
Avalos, A.M.2
Mao, S.Y.3
-
60
-
-
33746731651
-
HMGB1 signals through Toll-like receptor (TLR) 4 and TLR2
-
Yu M, Wang H, Ding A, et al. HMGB1 signals through Toll-like receptor (TLR) 4 and TLR2. Shock 2006;26: 174-9
-
(2006)
Shock
, vol.26
, pp. 174-179
-
-
Yu, M.1
Wang, H.2
Ding, A.3
-
61
-
-
80052330985
-
Glucan phosphate attenuates myocardial HMGB1 translocation in severe sepsis through inhibiting NF-kappaB activation
-
Ha T, Xia Y, Liu X, et al. Glucan phosphate attenuates myocardial HMGB1 translocation in severe sepsis through inhibiting NF-kappaB activation. Am J Physiol Heart Circ Physiol 2011;301:H848-55
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Ha, T.1
Xia, Y.2
Liu, X.3
-
62
-
-
80555126061
-
Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells
-
Xiang M, Shi X, Li Y, et al. Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells. J Immunol 2011;187: 4809-17
-
(2011)
J Immunol
, vol.187
, pp. 4809-4817
-
-
Xiang, M.1
Shi, X.2
Li, Y.3
-
63
-
-
63149171602
-
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses
-
Chen GY, Tang J, Zheng P, Liu Y. CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. Science 2009;323: 1722-5 • These authors first reported CD24 as another potential cell surface receptor for HMGB1.
-
(2009)
Science
, vol.323
, pp. 1722-1725
-
-
Chen, G.Y.1
Tang, J.2
Zheng, P.3
Liu, Y.4
-
64
-
-
20944436774
-
The N-terminal domain of thrombomodulin sequesters high-mobility group- B1 protein, a novel antiinflammatory mechanism
-
Abeyama K, Stern DM, Ito Y, et al. The N-terminal domain of thrombomodulin sequesters high-mobility group- B1 protein, a novel antiinflammatory mechanism. J Clin Invest 2005;115: 1267-74 • These authors first reported the presence of endogenous HMGB1- binding protein that functions as HMGB1-inhibiting agent.
-
(2005)
J Clin Invest
, vol.115
, pp. 1267-1274
-
-
Abeyama, K.1
Stern, D.M.2
Ito, Y.3
-
65
-
-
0026736041
-
Neurite growth-promoting protein (amphoterin, p30) binds syndecan
-
Salmivirta M, Rauvala H, Elenius K, et al. Neurite growth-promoting protein (amphoterin, p30) binds syndecan. Exp Cell Res 1992;200: 444-51 • These authors first reported the presence of HMGB1 outside of the nucleus (on the cytoplasmic membrane).
-
(1992)
Exp Cell Res
, vol.200
, pp. 444-451
-
-
Salmivirta, M.1
Rauvala, H.2
Elenius, K.3
-
66
-
-
1542380035
-
Involvement of TLR 2 and TLR 4 in cellular activation by high mobility group box 1 protein (HMGB1)
-
Park JS, Svetkauskaite D, He Q, et al. Involvement of TLR 2 and TLR 4 in cellular activation by high mobility group box 1 protein (HMGB1). J Biol Chem 2004;279: 7370-7
-
(2004)
J Biol Chem
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
-
67
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park JS, Gamboni-Robertson F, He Q, et al. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 2006;290:C917-24
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Park, J.S.1
Gamboni-Robertson, F.2
He, Q.3
-
68
-
-
19944431800
-
RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
-
Kokkola R, Andersson A, Mullins G, et al. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol 2005;61: 1-9
-
(2005)
Scand J Immunol
, vol.61
, pp. 1-9
-
-
Kokkola, R.1
Andersson, A.2
Mullins, G.3
-
69
-
-
40049101198
-
Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling
-
Pedrazzi M, Patrone M, Passalacqua M, et al. Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling. J Immunol 2007;179: 8525-32
-
(2007)
J Immunol
, vol.179
, pp. 8525-8532
-
-
Pedrazzi, M.1
Patrone, M.2
Passalacqua, M.3
-
70
-
-
0037769813
-
Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
-
Fiuza C, Bustin M, Talwar S, et al. Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 2003;101: 2652-60
-
(2003)
Blood
, vol.101
, pp. 2652-2660
-
-
Fiuza, C.1
Bustin, M.2
Talwar, S.3
-
71
-
-
0141750710
-
High mobility group 1 B-box mediates activation of human endothelium
-
Treutiger CJ, Mullins GE, Johansson AS, et al. High mobility group 1 B-box mediates activation of human endothelium. J Intern Med 2003;254: 375-85 • These authors first reported that HMGB1 activates non-immune cells.
-
(2003)
J Intern Med
, vol.254
, pp. 375-385
-
-
Treutiger, C.J.1
Mullins, G.E.2
Johansson, A.S.3
-
72
-
-
46749136790
-
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
-
Kazama H, Ricci JE, Herndon JM, et al. Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein. Immunity 2008;29: 21-32
-
(2008)
Immunity
, vol.29
, pp. 21-32
-
-
Kazama, H.1
Ricci, J.E.2
Herndon, J.M.3
-
73
-
-
84860862890
-
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
-
Yang H, Lundback P, Ottosson L, et al. Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med 2012;18: 250-9
-
(2012)
Mol Med
, vol.18
, pp. 250-259
-
-
Yang, H.1
Lundback, P.2
Ottosson, L.3
-
74
-
-
84866378556
-
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
-
Venereau E, Casalgrandi M, Schiraldi M, et al. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med 2012;209: 1519-28 • These authors further examined the effects of the redox status of HMGB1 affects its cytokine activities.
-
(2012)
J Exp Med
, vol.209
, pp. 1519-1528
-
-
Venereau, E.1
Casalgrandi, M.2
Schiraldi, M.3
-
75
-
-
84870781509
-
A Janus tale of two active high mobility group box 1 (HMGB1) redox states
-
Tang D, Billiar TR, Lotze MT. A Janus tale of two active high mobility group box 1 (HMGB1) redox states. Mol Med 2012;18: 1360-2
-
(2012)
Mol Med
, vol.18
, pp. 1360-1362
-
-
Tang, D.1
Billiar, T.R.2
Lotze, M.T.3
-
76
-
-
0018964280
-
Sepsis and septic shock - A review of laboratory models and a proposal
-
Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock - A review of laboratory models and a proposal. J Surg Res 1980;29: 189-201
-
(1980)
J Surg Res
, vol.29
, pp. 189-201
-
-
Wichterman, K.A.1
Baue, A.E.2
Chaudry, I.H.3
-
77
-
-
84860688160
-
Use of animal model of sepsis to evaluate novel herbal therapies
-
Li W, Zhu S, Zhang Y, et al. Use of animal model of sepsis to evaluate novel herbal therapies. J Vis Exp 2012((62)): 3926
-
(2012)
J Vis Exp
, Issue.62
, pp. 3926
-
-
Li, W.1
Zhu, S.2
Zhang, Y.3
-
78
-
-
9144241208
-
Reversing established sepsis with antagonists of endogenous high-mobility group box 1
-
Yang H, Ochani M, Li J, et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci USA 2004;101: 296-301 • These authors first reported the extracellular role of HMGB1 as a late mediator of lethal sepsis.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 296-301
-
-
Yang, H.1
Ochani, M.2
Li, J.3
-
79
-
-
0035891570
-
HMGB1 as a Late Mediator of Lethal Systemic Inflammation
-
Wang H, Yang H, Czura CJ, et al. HMGB1 as a Late Mediator of Lethal Systemic Inflammation. Am J Respir Crit Care Med 2001;164: 1768-73
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1768-1773
-
-
Wang, H.1
Yang, H.2
Czura, C.J.3
-
80
-
-
0034664791
-
HMG-1 as a mediator of acute lung inflammation
-
Abraham E, Arcaroli J, Carmody A, et al. HMG-1 as a mediator of acute lung inflammation. J Immunol 2000;165: 2950-4
-
(2000)
J Immunol
, vol.165
, pp. 2950-2954
-
-
Abraham, E.1
Arcaroli, J.2
Carmody, A.3
-
81
-
-
33745854493
-
Role of HMGB1 in apoptosis-mediated sepsis lethality
-
Qin S, Wang H, Yuan R, et al. Role of HMGB1 in apoptosis-mediated sepsis lethality. J Exp Med 2006;203: 1637-42
-
(2006)
J Exp Med
, vol.203
, pp. 1637-1642
-
-
Qin, S.1
Wang, H.2
Yuan, R.3
-
82
-
-
33748760336
-
Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis
-
Suda K, Kitagawa Y, Ozawa S, et al. Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. World J Surg 2006;30: 1755-62
-
(2006)
World J Surg
, vol.30
, pp. 1755-1762
-
-
Suda, K.1
Kitagawa, Y.2
Ozawa, S.3
-
83
-
-
0029036182
-
Steroid controversy in sepsis and septic shock: A meta-analysis
-
Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit Care Med 1995;23: 1294-303
-
(1995)
Crit Care Med
, vol.23
, pp. 1294-1303
-
-
Lefering, R.1
Neugebauer, E.A.2
-
84
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002;288: 862-71
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
-
85
-
-
38049110809
-
Hydrocortisone therapy for patients with septic shock
-
Sprung CL, Annane D, Keh D, et al. Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008;358: 111-24
-
(2008)
N Engl J Med
, vol.358
, pp. 111-124
-
-
Sprung, C.L.1
Annane, D.2
Keh, D.3
-
86
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345: 1368-77
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
87
-
-
40049109098
-
Vasopressin versus norepinephrine infusion in patients with septic shock
-
Russell JA, Walley KR, Singer J, et al. Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med 2008;358: 877-87
-
(2008)
N Engl J Med
, vol.358
, pp. 877-887
-
-
Russell, J.A.1
Walley, K.R.2
Singer, J.3
-
88
-
-
52949139051
-
High-dose intravenous immunoglobulin G improves systemic inflammation in a rat model of CLPinduced sepsis
-
Hagiwara S, Iwasaka H, Hasegawa A, et al. High-dose intravenous immunoglobulin G improves systemic inflammation in a rat model of CLPinduced sepsis. Intensive Care Med 2008;34: 1812-19
-
(2008)
Intensive Care Med
, vol.34
, pp. 1812-1819
-
-
Hagiwara, S.1
Iwasaka, H.2
Hasegawa, A.3
-
89
-
-
38849155079
-
High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats
-
Hagiwara S, Iwasaka H, Matsumoto S, Noguchi T. High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats. Intensive Care Med 2008;34: 361-7
-
(2008)
Intensive Care Med
, vol.34
, pp. 361-367
-
-
Hagiwara, S.1
Iwasaka, H.2
Matsumoto, S.3
Noguchi, T.4
-
90
-
-
79951559422
-
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation
-
Li W, Zhu S, Li J, et al. A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. PLoS One 2011;6:e16945
-
(2011)
PLoS One
, vol.6
-
-
Li, W.1
Zhu, S.2
Li, J.3
-
91
-
-
49949089651
-
Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model
-
Hagiwara S, Iwasaka H, Hasegawa A, et al. Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model. Crit Care Med 2008;36: 2407-13
-
(2008)
Crit Care Med
, vol.36
, pp. 2407-2413
-
-
Hagiwara, S.1
Iwasaka, H.2
Hasegawa, A.3
-
92
-
-
43449087928
-
Neuropeptides rescue mice from lethal sepsis by downregulating secretion of the late-acting inflammatory mediator high mobility group box 1
-
Chorny A, Delgado M. Neuropeptides rescue mice from lethal sepsis by downregulating secretion of the late-acting inflammatory mediator high mobility group box 1. Am J Pathol 2008;172: 1297-307
-
(2008)
Am J Pathol
, vol.172
, pp. 1297-1307
-
-
Chorny, A.1
Delgado, M.2
-
93
-
-
50949098239
-
Ghrelin protects against experimental sepsis by inhibiting highmobility group box 1 release and by killing bacteria
-
Chorny A, Anderson P, Gonzalez-Rey E, Delgado M. Ghrelin protects against experimental sepsis by inhibiting highmobility group box 1 release and by killing bacteria. J Immunol 2008;180: 8369-77
-
(2008)
J Immunol
, vol.180
, pp. 8369-8377
-
-
Chorny, A.1
Anderson, P.2
Gonzalez-Rey, E.3
Delgado, M.4
-
94
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
-
Wang H, Yu M, Ochani M, et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003;421: 384-8
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
-
95
-
-
1642602647
-
Lipid unites disparate syndromes of sepsis
-
Wang H, Czura CJ, Tracey KJ. Lipid unites disparate syndromes of sepsis. Nat Med 2004;10: 124-5
-
(2004)
Nat Med
, vol.10
, pp. 124-125
-
-
Wang, H.1
Czura, C.J.2
Tracey, K.J.3
-
96
-
-
83455196941
-
Glutamine administration ameliorates sepsis-induced kidney injury by downregulating the high-mobility group box protein-1-mediated pathway in mice
-
Hu YM, Pai MH, Yeh CL, et al. Glutamine administration ameliorates sepsis-induced kidney injury by downregulating the high-mobility group box protein-1-mediated pathway in mice. Am J Physiol Renal Physiol 2012;302:F150-8
-
(2012)
Am J Physiol Renal Physiol
, vol.302
-
-
Hu, Y.M.1
Pai, M.H.2
Yeh, C.L.3
-
97
-
-
32544438027
-
The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis
-
Wang H, Li W, Li J, et al. The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis. J Nutr 2006;136: 360-5 • This is the first report showing that herbal extract inhibited HMGB1 release and protected against lethal sepsis.
-
(2006)
J Nutr
, vol.136
, pp. 360-365
-
-
Wang, H.1
Li, W.2
Li, J.3
-
98
-
-
84870207332
-
It is not just folklore: The aqueous extract of mung bean coat is protective against Sepsis
-
Zhu S, Li W, Li J, et al. It is not just folklore: the aqueous extract of mung bean coat is protective against Sepsis. Evid Based Complement Alternat Med 2012;2012: 498467
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 498467
-
-
Zhu, S.1
Li, W.2
Li, J.3
-
99
-
-
84859621252
-
Ethanol extract of Prunella vulgaris var lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPSactivated RAW 264.7 cells and CLPinduced septic mice
-
Jun MS, Kim HS, Kim YM, et al. Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPSactivated RAW 264.7 cells and CLPinduced septic mice. Phytother Res 2012;26: 605-12
-
(2012)
Phytother Res
, vol.26
, pp. 605-612
-
-
Jun, M.S.1
Kim, H.S.2
Kim, Y.M.3
-
100
-
-
9144263639
-
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
-
Wang H, Liao H, Ochani M, et al. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med 2004;10: 1216-21
-
(2004)
Nat Med
, vol.10
, pp. 1216-1221
-
-
Wang, H.1
Liao, H.2
Ochani, M.3
-
101
-
-
42649094198
-
A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1
-
Li W, Ashok M, Li J, et al. A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. PLoS One 2007;2:e1153
-
(2007)
PLoS One
, vol.2
-
-
Li, W.1
Ashok, M.2
Li, J.3
-
102
-
-
33947194239
-
A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1
-
Li W, Li J, Ashok M, et al. A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1. J Immunol 2007;178: 3856-64
-
(2007)
J Immunol
, vol.178
, pp. 3856-3864
-
-
Li, W.1
Li, J.2
Ashok, M.3
-
103
-
-
84874672440
-
Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response
-
Wang W, Zhao F, Fang Y, et al. Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response. Crit Care 2013;17:R44
-
(2013)
Crit Care
, vol.17
-
-
Wang, W.1
Zhao, F.2
Fang, Y.3
-
104
-
-
84872224514
-
Chlorogenic acid attenuates high mobility group box 1 (HMGB1) and enhances host defense mechanisms in murine sepsis
-
Lee CH, Yoon SJ, Lee SM. Chlorogenic acid attenuates high mobility group box 1 (HMGB1) and enhances host defense mechanisms in murine sepsis. Mol Med 2013;18: 1437-48
-
(2013)
Mol Med
, vol.18
, pp. 1437-1448
-
-
Lee, C.H.1
Yoon, S.J.2
Lee, S.M.3
-
105
-
-
84870544257
-
Emodin-6-O-beta-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo
-
Lee W, Ku SK, Kim TH, Bae JS. Emodin-6-O-beta-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem Toxicol 2013;52: 97-104
-
(2013)
Food Chem Toxicol
, vol.52
, pp. 97-104
-
-
Lee, W.1
Ku, S.K.2
Kim, T.H.3
Bae, J.S.4
-
106
-
-
84873837572
-
Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatory responses in vitro and in vivo
-
Yang EJ, Ku SK, Lee W, et al. Barrier protective effects of rosmarinic acid on HMGB1-induced inflammatory responses in vitro and in vivo. J Cell Physiol 2013;228: 975-82
-
(2013)
J Cell Physiol
, vol.228
, pp. 975-982
-
-
Yang, E.J.1
Ku, S.K.2
Lee, W.3
-
107
-
-
84872735026
-
Anti-inflammatory activities of isorhamnetin-3-O-galactoside against HMGB1-induced inflammatory responses in both HUVECs and CLPinduced septic mice
-
Kim TH, Ku SK, Bae JS. Anti-inflammatory activities of isorhamnetin-3-O-galactoside against HMGB1-induced inflammatory responses in both HUVECs and CLPinduced septic mice. J Cell Biochem 2013;114: 336-45
-
(2013)
J Cell Biochem
, vol.114
, pp. 336-345
-
-
Kim, T.H.1
Ku, S.K.2
Bae, J.S.3
-
108
-
-
84871699273
-
Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLPinduced sepsis mice
-
Kim TH, Ku SK, Bae JS. Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLPinduced sepsis mice. J Cell Physiol 2013;228: 696-703
-
(2013)
J Cell Physiol
, vol.228
, pp. 696-703
-
-
Kim, T.H.1
Ku, S.K.2
Bae, J.S.3
-
109
-
-
84863723893
-
Forsythoside B protects against experimental sepsis by modulating inflammatory factors
-
Jiang WL, Yong X, Zhang SP, et al. Forsythoside B protects against experimental sepsis by modulating inflammatory factors. Phytother Res 2012;26: 981-7
-
(2012)
Phytother Res
, vol.26
, pp. 981-987
-
-
Jiang, W.L.1
Yong, X.2
Zhang, S.P.3
-
110
-
-
84884540574
-
Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis
-
Yang M, Cao L, Xie M, et al. Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis. Biochem Pharmacol 2013;86(3): 410-18
-
(2013)
Biochem Pharmacol
, vol.86
, Issue.3
, pp. 410-418
-
-
Yang, M.1
Cao, L.2
Xie, M.3
-
111
-
-
84880698787
-
Acteoside improves survival in cecal ligation and puncture-induced septic mice via blocking of high mobility group box 1 release
-
Seo ES, Oh BK, Pak JH, et al. Acteoside improves survival in cecal ligation and puncture-induced septic mice via blocking of high mobility group box 1 release. Mol Cells 2013;35: 348-54
-
(2013)
Mol Cells
, vol.35
, pp. 348-354
-
-
Seo, E.S.1
Oh, B.K.2
Pak, J.H.3
-
112
-
-
79953685881
-
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxinstimulated macrophages
-
Li W, Zhu S, Li J, et al. EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxinstimulated macrophages. Biochem Pharmacol 2011;81: 1152-63
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 1152-1163
-
-
Li, W.1
Zhu, S.2
Li, J.3
-
113
-
-
84868503604
-
Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake
-
Zhang Y, Li W, Zhu S, et al. Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake. Biochem Pharmacol 2012;84: 1492-500
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 1492-1500
-
-
Zhang, Y.1
Li, W.2
Zhu, S.3
-
114
-
-
84874919170
-
Regulation of HMGB1 release by inflammasomes
-
Lu B, Wang H, Andersson U, et al. Regulation of HMGB1 release by inflammasomes. Protein Cell 2013;4: 163-7
-
(2013)
Protein Cell
, vol.4
, pp. 163-167
-
-
Lu, B.1
Wang, H.2
Andersson, U.3
-
115
-
-
0032411659
-
Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model
-
Yang F, de Villiers WJ, McClain CJ, Varilek GW. Green tea polyphenols block endotoxin-induced tumor necrosis factor-production and lethality in a murine model. J Nutr 1998;128: 2334-40
-
(1998)
J Nutr
, vol.128
, pp. 2334-2340
-
-
Yang, F.1
De Villiers, W.J.2
McClain, C.J.3
Varilek, G.W.4
-
116
-
-
16644391108
-
Effect of various catechins on the IL- 12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.1
-
Ichikawa D, Matsui A, Imai M, et al. Effect of various catechins on the IL- 12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.1. Biol Pharm Bull 2004;27: 1353-8
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 1353-1358
-
-
Ichikawa, D.1
Matsui, A.2
Imai, M.3
-
117
-
-
33746190736
-
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality
-
Osuchowski MF, Welch K, Siddiqui J, Remick DG. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol 2006;177: 1967-74
-
(2006)
J Immunol
, vol.177
, pp. 1967-1974
-
-
Osuchowski, M.F.1
Welch, K.2
Siddiqui, J.3
Remick, D.G.4
-
118
-
-
3142730480
-
Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis
-
Heuer JG, Sharma GR, Gerlitz B, et al. Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis. Crit Care Med 2004;32: 1570-8
-
(2004)
Crit Care Med
, vol.32
, pp. 1570-1578
-
-
Heuer, J.G.1
Sharma, G.R.2
Gerlitz, B.3
-
119
-
-
84880656352
-
Carbenoxolone Blocks Endotoxin- Induced Protein Kinase R (PKR) Activation and High Mobility Group Box 1 (HMGB1) Release
-
Li W, Li J, Sama AE, et al. Carbenoxolone Blocks Endotoxin- Induced Protein Kinase R (PKR) Activation and High Mobility Group Box 1 (HMGB1) Release. Mol Med 2013;19: 203-11
-
(2013)
Mol Med
, vol.19
, pp. 203-211
-
-
Li, W.1
Li, J.2
Sama, A.E.3
-
120
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial
-
The HA- 1A Sepsis Study Group
-
Ziegler EJ, Fisher CJ Jr, Sprung CL, et al. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA- 1A Sepsis Study Group. N Engl J Med 1991;324: 429-36
-
(1991)
N Engl J Med
, vol.324
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher Jr., C.J.2
Sprung, C.L.3
-
121
-
-
0034675328
-
Recombinant bactericidal/permeabilityincreasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: A randomised trial
-
rBPI21 Meningococcal Sepsis Study Group
-
Levin M, Quint PA, Goldstein B, et al. Recombinant bactericidal/ permeabilityincreasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. Lancet 2000;356: 961-7
-
(2000)
Lancet
, vol.356
, pp. 961-967
-
-
Levin, M.1
Quint, P.A.2
Goldstein, B.3
-
122
-
-
84875124740
-
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: The ACCESS randomized trial
-
Opal SM, Laterre PF, Francois B, et al. Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial. JAMA 2013;309: 1154-62
-
(2013)
JAMA
, vol.309
, pp. 1154-1162
-
-
Opal, S.M.1
Laterre, P.F.2
Francois, B.3
-
123
-
-
84883790050
-
Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock
-
Hagar JA, Powell DA, Aachoui Y, et al. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science 2013;341: 1250-3 • These authors first reported a TLR4- independent cytoplasmic signaling pathway for endotoxin-mediated inflammasome activation and cytokine release.
-
(2013)
Science
, vol.341
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
-
124
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N, Wong MT, Stowe IB, et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 2013;341: 1246-9 • These authors first reported a cytoplasmic signaling pathway involved in endotoxin-mediated inflammasome activation and cytokine release.
-
(2013)
Science
, vol.341
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
-
125
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 1985;229: 869-71 • These authors first reported a pathogenic role of TNF in lethal endotoxemia.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.C.3
-
126
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial
-
TNF-alpha MAb Sepsis Study Group
-
Abraham E, Wunderink R, Silverman H, et al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group. JAMA 1995;273: 934-41
-
(1995)
JAMA
, vol.273
, pp. 934-941
-
-
Abraham, E.1
Wunderink, R.2
Silverman, H.3
-
127
-
-
0035056003
-
Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned?
-
Feldmann M, Maini RN. Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? Annu Rev Immunol 2001;19: 163-96
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
128
-
-
79951848606
-
The potential effect and mechanism of highmobility group box 1 protein on regulatory T cell-mediated immunosuppression
-
Zhang Y, Yao YM, Huang LF, et al. The potential effect and mechanism of highmobility group box 1 protein on regulatory T cell-mediated immunosuppression. J Interferon Cytokine Res 2011;31: 249-57
-
(2011)
J Interferon Cytokine Res
, vol.31
, pp. 249-257
-
-
Zhang, Y.1
Yao, Y.M.2
Huang, L.F.3
-
129
-
-
84865084552
-
HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells
-
Wild CA, Bergmann C, Fritz G, et al. HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells. Int Immunol 2012;24: 485-94
-
(2012)
Int Immunol
, vol.24
, pp. 485-494
-
-
Wild, C.A.1
Bergmann, C.2
Fritz, G.3
-
130
-
-
55549133613
-
Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance
-
Aneja RK, Tsung A, Sjodin H, et al. Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance. J Leukoc Biol 2008;84: 1326-34
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1326-1334
-
-
Aneja, R.K.1
Tsung, A.2
Sjodin, H.3
-
131
-
-
77955172640
-
Preconditioning with high mobility group box 1 (HMGB1) induces lipoteichoic acid (LTA) tolerance
-
Robert SM, Sjodin H, Fink MP, et al. Preconditioning with high mobility group box 1 (HMGB1) induces lipoteichoic acid (LTA) tolerance. J Immunother 2010;33: 663-71
-
(2010)
J Immunother
, vol.33
, pp. 663-671
-
-
Robert, S.M.1
Sjodin, H.2
Fink, M.P.3
-
132
-
-
84865631414
-
Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis
-
Entezari M, Weiss DJ, Sitapara R, et al. Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis. Mol Med 2012;18: 477-85 • These author first reported the extracellular role of HMGB1 in the impairment of bacterial elimination by macrophages.
-
(2012)
Mol Med
, vol.18
, pp. 477-485
-
-
Entezari, M.1
Weiss, D.J.2
Sitapara, R.3
-
133
-
-
84874877646
-
High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice
-
Patel VS, Sitapara RA, Gore A, et al. High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice. Am J Respir Cell Mol Biol 2013;48: 280-7
-
(2013)
Am J Respir Cell Mol Biol
, vol.48
, pp. 280-287
-
-
Patel, V.S.1
Sitapara, R.A.2
Gore, A.3
-
134
-
-
56049106702
-
High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine
-
Liu G, Wang J, Park YJ, et al. High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine. J Immunol 2008;181: 4240-6
-
(2008)
J Immunol
, vol.181
, pp. 4240-4246
-
-
Liu, G.1
Wang, J.2
Park, Y.J.3
-
135
-
-
0034534954
-
Salvia miltiorrhiza and ischemic diseases
-
Ji XY, Tan BK, Zhu YZ. Salvia miltiorrhiza and ischemic diseases. Acta Pharmacol Sin 2000;21: 1089-94
-
(2000)
Acta Pharmacol Sin
, vol.21
, pp. 1089-1094
-
-
Ji, X.Y.1
Tan, B.K.2
Zhu, Y.Z.3
|