-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2: 675-680, 2001.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
0034698830
-
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
-
Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, Janson A, Kokkola R, Zhang M, Yang H, Tracey KJ. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 192: 565-570, 2000.
-
(2000)
J Exp Med
, vol.192
, pp. 565-570
-
-
Andersson, U.1
Wang, H.2
Palmblad, K.3
Aveberger, A.C.4
Bloom, O.5
Erlandsson-Harris, H.6
Janson, A.7
Kokkola, R.8
Zhang, M.9
Yang, H.10
Tracey, K.J.11
-
3
-
-
33646347668
-
Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia
-
Baumgarten G, Kneufermann P, Schuhmacher G, Vervolgyi V, von Rappard J, Dreiner U, Fink K, Djoufack C, Hoeft A, Grohe C, Knowlton AA, Meyer R. Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia. Shock 25: 43-49, 2006.
-
(2006)
Shock
, vol.25
, pp. 43-49
-
-
Baumgarten, G.1
Kneufermann, P.2
Schuhmacher, G.3
Vervolgyi, V.4
von Rappard, J.5
Dreiner, U.6
Fink, K.7
Djoufack, C.8
Hoeft, A.9
Grohe, C.10
Knowlton, A.A.11
Meyer, R.12
-
4
-
-
33845951211
-
DAMPs, PAMPs and alarmins: All we need to know about danger
-
Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81: 1-5, 2006.
-
(2006)
J Leukoc Biol
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
5
-
-
0037025994
-
Dectin-1 is a major β-glucan receptor on macrophages
-
Brown GD, Taylor PR, Reid DM, Willment JA, Williams DL, Martinez-Pomares L, Wong SYC, Gordon S. Dectin-1 is a major β-glucan receptor on macrophages. J Exp Med 296: 412, 2002.
-
(2002)
J Exp Med
, vol.296
, pp. 412
-
-
Brown, G.D.1
Taylor, P.R.2
Reid, D.M.3
Willment, J.A.4
Williams, D.L.5
Martinez-Pomares, L.6
Wong, S.Y.C.7
Gordon, S.8
-
6
-
-
20344397715
-
Endotoxin-induced myocardial dysfunction effects of macrophage migration inhibitory factor neutralization
-
Chagnon F, Metz CN, Bucala R, Lesur O. Endotoxin-induced myocardial dysfunction effects of macrophage migration inhibitory factor neutralization. Circ Res 96: 1095-1102, 2005.
-
(2005)
Circ Res
, vol.96
, pp. 1095-1102
-
-
Chagnon, F.1
Metz, C.N.2
Bucala, R.3
Lesur, O.4
-
7
-
-
0037199972
-
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
-
Guha M, Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem 277: 32124-32132, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 32124-32132
-
-
Guha, M.1
Mackman, N.2
-
8
-
-
77955888865
-
TLR2 ligands induce cardioprotection against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism
-
Ha T, Hu Y, Liu L, Lu C, McMullen JR, Shioi T, Isumo S, Kelley J, Kao RL, Williams DL, Gao X, Li C. TLR2 ligands induce cardioprotection against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism. Cardiovasc Res 87: 694-703, 2010.
-
(2010)
Cardiovasc Res
, vol.87
, pp. 694-703
-
-
Ha, T.1
Hu, Y.2
Liu, L.3
Lu, C.4
McMullen, J.R.5
Shioi, T.6
Isumo, S.7
Kelley, J.8
Kao, R.L.9
Williams, D.L.10
Gao, X.11
Li, C.12
-
9
-
-
33749336485
-
Glucan phosphate attenuates cardiac dysfunction and inhibits cardiac MIF expression and apoptosis in septic mice
-
Ha T, Hua F, Grant D, Xia Y, Ma J, Gao X, Kelley J, Williams DL, Kablfleisch J, Browder IW, Li C. Glucan phosphate attenuates cardiac dysfunction and inhibits cardiac MIF expression and apoptosis in septic mice. Am J Physiol Heart Circ Physiol 291: H1910-H1918, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Ha, T.1
Hua, F.2
Grant, D.3
Xia, Y.4
Ma, J.5
Gao, X.6
Kelley, J.7
Williams, D.L.8
Kablfleisch, J.9
Browder, I.W.10
Li, C.11
-
10
-
-
33645750471
-
Blockade of MyD88 attenuates cardiac hypertrophy and decreases cardiac myocyte apoptosis in pressure overload induced cardiac hypertrophy in vivo
-
Ha T, Hua F, Li Y, Ma J, Gao X, Kelley J, Zhao A, Haddad GE, Williams DL, Browder IW, Kao RL, Li C. Blockade of MyD88 attenuates cardiac hypertrophy and decreases cardiac myocyte apoptosis in pressure overload induced cardiac hypertrophy in vivo. Am J Physiol Heart Circ Physiol 290: H985-H994, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Ha, T.1
Hua, F.2
Li, Y.3
Ma, J.4
Gao, X.5
Kelley, J.6
Zhao, A.7
Haddad, G.E.8
Williams, D.L.9
Browder, I.W.10
Kao, R.L.11
Li, C.12
-
11
-
-
77749242763
-
TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide-3-kinase dependent mechanism
-
Ha T, Lu C, Liu L, Hua F, Hu Y, Kelley J, Singh K, Kao RL, Kalbfleisch J, Williams DL, Gao X, Li C. TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide-3-kinase dependent mechanism. Am J Physiol Heart Circ Physiol 298: H984-H991, 2010.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Ha, T.1
Lu, C.2
Liu, L.3
Hua, F.4
Hu, Y.5
Kelley, J.6
Singh, K.7
Kao, R.L.8
Kalbfleisch, J.9
Williams, D.L.10
Gao, X.11
Li, C.12
-
12
-
-
0034975025
-
Overexpression of cardiac I-κBα prevents endotoxininduced myocardial dysfunction
-
Haudek SB, Spencer E, Bryant DD, White DJ, Maass D, Horton JW, Chen ZJ, Giroir BP. Overexpression of cardiac I-κBα prevents endotoxininduced myocardial dysfunction. Am J Physiol Heart Circ Physiol 280: H962-H968, 2001.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Haudek, S.B.1
Spencer, E.2
Bryant, D.D.3
White, D.J.4
Maass, D.5
Horton, J.W.6
Chen, Z.J.7
Giroir, B.P.8
-
13
-
-
34249787873
-
Protection against myocardial ischemia/reperfusion injury in TLR4 deficient mice is mediated through a phosphoinositide 3-kinase dependent mechanism
-
Hua F, Ha T, Ma J, Li Y, Kelley J, Gao X, Browder IW, Kao RL, Williams DL, Li C. Protection against myocardial ischemia/reperfusion injury in TLR4 deficient mice is mediated through a phosphoinositide 3-kinase dependent mechanism. J Immunol 178: 7317-7324, 2007.
-
(2007)
J Immunol
, vol.178
, pp. 7317-7324
-
-
Hua, F.1
Ha, T.2
Ma, J.3
Li, Y.4
Kelley, J.5
Gao, X.6
Browder, I.W.7
Kao, R.L.8
Williams, D.L.9
Li, C.10
-
14
-
-
48149096398
-
HMGB1: Endogenous danger signaling
-
Klune JR, Dhupar R, Cardinal J, Billiar TR, Tsung A. HMGB1: endogenous danger signaling. Mo Med 14: 476-484, 2008.
-
(2008)
Mo Med
, vol.14
, pp. 476-484
-
-
Klune, J.R.1
Dhupar, R.2
Cardinal, J.3
Billiar, T.R.4
Tsung, A.5
-
15
-
-
0032988969
-
Early activation of transcription factor NF-κB during ischemia in perfused rat heart
-
Li C, Browder W, Kao RL. Early activation of transcription factor NF-κB during ischemia in perfused rat heart. Am J Physiol Heart Circ Physiol 276: H543-H552, 1999.
-
(1999)
Am J Physiol Heart Circ Physiol
, vol.276
-
-
Li, C.1
Browder, W.2
Kao, R.L.3
-
16
-
-
1142309739
-
Modulating toll-like receptor mediated signaling by (1->3)-β-Dglucan rapidly induces cardioprotection
-
Li C, Ha T, Kelley J, Gao X, Qiu Y, Kao RL, Browder W, Williams DL. Modulating toll-like receptor mediated signaling by (1->3)-β-Dglucan rapidly induces cardioprotection. Cardiovasc Res 61: 538-547, 2003.
-
(2003)
Cardiovasc Res
, vol.61
, pp. 538-547
-
-
Li, C.1
Ha, T.2
Kelley, J.3
Gao, X.4
Qiu, Y.5
Kao, R.L.6
Browder, W.7
Williams, D.L.8
-
17
-
-
7444265939
-
NK-κB activation is required for the development of cardiac hypertrophy in vivo
-
Li Y, Ha T, Gao X, Kelley J, Williams DL, Browder IW, Kao RL, Li C. NK-κB activation is required for the development of cardiac hypertrophy in vivo. Am J Physiol Heart Circ Physiol 287: H1712-H1720, 2004.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Li, Y.1
Ha, T.2
Gao, X.3
Kelley, J.4
Williams, D.L.5
Browder, I.W.6
Kao, R.L.7
Li, C.8
-
18
-
-
24644495576
-
Implication of toll-like receptor and tumor necrosis factor α signaling in septic shock
-
Lin WJ, Yeh WC. Implication of toll-like receptor and tumor necrosis factor α signaling in septic shock. Shock 24: 206-209, 2005.
-
(2005)
Shock
, vol.24
, pp. 206-209
-
-
Lin, W.J.1
Yeh, W.C.2
-
19
-
-
0030831210
-
A human homologue of the Drosophila toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila toll protein signals activation of adaptive immunity. Nature 388: 394-397, 1997.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
20
-
-
0036086439
-
Escherichia coli LPS-induced LV dysfunction: Role of toll-like receptor-4 in the adult heart
-
Nemoto S, Vallejo JG, Kneufermann P, Misra A, Defreitas G, Carabello BA, Mann DL. Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart. Am J Physiol Heart Circ Physiol 282: H2316-H2323, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Nemoto, S.1
Vallejo, J.G.2
Kneufermann, P.3
Misra, A.4
Defreitas, G.5
Carabello, B.A.6
Mann, D.L.7
-
21
-
-
0036220027
-
Bench-to-bedside review: Toll-like receptors and their role in septic shock
-
Opal SM, Huber CE. Bench-to-bedside review: toll-like receptors and their role in septic shock. Crit Care 6: 125-136, 2002.
-
(2002)
Crit Care
, vol.6
, pp. 125-136
-
-
Opal, S.M.1
Huber, C.E.2
-
22
-
-
35349009132
-
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-κB activation
-
Palumbo R, Galvez BG, Pusterla T, De Marchis F, Cossu G, Marcu KB, Bianchi ME. Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-κB activation. J Cell Biol 179: 33-40, 2007.
-
(2007)
J Cell Biol
, vol.179
, pp. 33-40
-
-
Palumbo, R.1
Galvez, B.G.2
Pusterla, T.3
de Marchis, F.4
Cossu, G.5
Marcu, K.B.6
Bianchi, M.E.7
-
23
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, Strassheim D, Sohn JW, Yamada S, Maruyama I, Banerjee A, Ishizaka A, Abraham E. High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 290: C917-C924, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Park, J.S.1
Gamboni-Robertson, F.2
He, Q.3
Svetkauskaite, D.4
Kim, J.Y.5
Strassheim, D.6
Sohn, J.W.7
Yamada, S.8
Maruyama, I.9
Banerjee, A.10
Ishizaka, A.11
Abraham, E.12
-
24
-
-
1542380035
-
Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, Abraham E. Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 279: 7370-7377, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 7370-7377
-
-
Park, J.S.1
Svetkauskaite, D.2
He, Q.3
Kim, J.Y.4
Strassheim, D.5
Ishizaka, A.6
Abraham, E.7
-
25
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418: 191-195, 2002.
-
(2002)
Nature
, vol.418
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
26
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
-
Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C, Hua J, An LL, Audoly L, La Rosa G, Bierhaus A, Naworth P, Marshak-Rothstein A, Crow MK, Fitzgerald KA, Latz E, Kiener PA, Coyle AJ. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 8: 487-496, 2007.
-
(2007)
Nat Immunol
, vol.8
, pp. 487-496
-
-
Tian, J.1
Avalos, A.M.2
Mao, S.Y.3
Chen, B.4
Senthil, K.5
Wu, H.6
Parroche, P.7
Drabic, S.8
Golenbock, D.9
Sirois, C.10
Hua, J.11
An, L.L.12
Audoly, L.13
la Rosa, G.14
Bierhaus, A.15
Naworth, P.16
Marshak-Rothstein, A.17
Crow, M.K.18
Fitzgerald, K.A.19
Latz, E.20
Kiener, P.A.21
Coyle, A.J.22
more..
-
27
-
-
41049117932
-
Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
-
van Beijnum JR, Buurman WA, Griffioen AW. Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis 11: 91-99, 2008.
-
(2008)
Angiogenesis
, vol.11
, pp. 91-99
-
-
van Beijnum, J.R.1
Buurman, W.A.2
Griffioen, A.W.3
-
28
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285: 248-251, 1999.
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
Vishnubhakat, J.M.4
Ombrellino, M.5
Che, J.6
Frazier, A.7
Yang, H.8
Ivanova, S.9
Borovikova, L.10
Manogue, K.R.11
Faist, E.12
Abraham, E.13
Andersson, J.14
Andersson, U.15
Molina, P.E.16
Abumrad, N.N.17
Sama, A.18
Tracey, K.J.19
-
29
-
-
9144263639
-
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
-
Wang H, Liao H, Ochani M, Justiniani M, Lin X, Yang L, Al-Abed Y, Wang H, Metz C, Miller EJ, Tracey KJ, Ulloa L. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nature Med 10: 1216-1221, 2004.
-
(2004)
Nature Med
, vol.10
, pp. 1216-1221
-
-
Wang, H.1
Liao, H.2
Ochani, M.3
Justiniani, M.4
Lin, X.5
Yang, L.6
Al-Abed, Y.7
Wang, H.8
Metz, C.9
Miller, E.J.10
Tracey, K.J.11
Ulloa, L.12
-
30
-
-
0032779231
-
Inhibiting early activation of tissue nuclear factor-κB and nuclear factor interleukin 6 with (1->3)-β-D-glucan increases long-term survival in polymicrobial sepsis
-
Williams DL, Ha T, Li C, Kalbfleisch JH, Laffan JJ, Ferguson DA. Inhibiting early activation of tissue nuclear factor-κB and nuclear factor interleukin 6 with (1->3)-β-D-glucan increases long-term survival in polymicrobial sepsis. Surgery 126: 54-65, 1999.
-
(1999)
Surgery
, vol.126
, pp. 54-65
-
-
Williams, D.L.1
Ha, T.2
Li, C.3
Kalbfleisch, J.H.4
Laffan, J.J.5
Ferguson, D.A.6
-
31
-
-
0038047587
-
Modulation of tissue toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality
-
Williams DL, Ha T, Li C, Kalbfleisch JH, Schweitzer J, Vogt W, Browder IW. Modulation of tissue toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality. Crit Care Med 31: 1808-1818, 2003.
-
(2003)
Crit Care Med
, vol.31
, pp. 1808-1818
-
-
Williams, D.L.1
Ha, T.2
Li, C.3
Kalbfleisch, J.H.4
Schweitzer, J.5
Vogt, W.6
Browder, I.W.7
-
32
-
-
0346103719
-
Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
-
Williams DL, Li C, Ha T, Ozment-Skelton T, Kalbfleisch JH, Preiszner J, Brooks L, Breuel K, Schweitzer JB. Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol 172: 449-456, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 449-456
-
-
Williams, D.L.1
Li, C.2
Ha, T.3
Ozment-Skelton, T.4
Kalbfleisch, J.H.5
Preiszner, J.6
Brooks, L.7
Breuel, K.8
Schweitzer, J.B.9
-
33
-
-
33646784031
-
Modulation of the phosphoinositide-3-kinase signaling pathway alters host resistance to sepsis, inflammation, and ischemia/reperfusion injury
-
Williams DL, Ozment-Skelton T, Li C. Modulation of the phosphoinositide-3-kinase signaling pathway alters host resistance to sepsis, inflammation, and ischemia/reperfusion injury. Shock 25: 432-439, 2006.
-
(2006)
Shock
, vol.25
, pp. 432-439
-
-
Williams, D.L.1
Ozment-Skelton, T.2
Li, C.3
-
34
-
-
0027111718
-
Development of a water-soluble, sulfated (1-3)-β-D-glucan biological response modifier derived from Saccharomyces cerevisiae
-
Williams DL, Pretus HA, McNamee RB, Jones EL, Ensley HE, Browder IW. Development of a water-soluble, sulfated (1-3)-β-D-glucan biological response modifier derived from Saccharomyces cerevisiae. Carbohydr Res 235: 247-257, 1992.
-
(1992)
Carbohydr Res
, vol.235
, pp. 247-257
-
-
Williams, D.L.1
Pretus, H.A.2
McNamee, R.B.3
Jones, E.L.4
Ensley, H.E.5
Browder, I.W.6
|