Carbenoxolone blocks endotoxin-induced protein kinase R (PKR) activation and high mobility group box 1 (HMGB1) release

Molecular Medicine

Volumn 19, Issue 1, 2013, Pages 203-211

  Li, Wei ^a,b   Li, Jianhua ^a   Sama, Andrew E ^b   Wang, Haichao ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBENOXOLONE; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; GRANULOCYTE COLONY STIMULATING FACTOR; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; NITRIC OXIDE; PADGEM PROTEIN; PROTEIN KINASE R; PURINERGIC P2X RECEPTOR; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; INNATE IMMUNITY; LETHARGY; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM LAVAGE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REFLEX; SEPSIS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CARBENOXOLONE; CELL LINE; CELLS, CULTURED; EIF-2 KINASE; HMGB1 PROTEIN; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; RECEPTORS, PURINERGIC P2X7; SEPSIS;

EID: 84880656352     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2013.00064     Document Type: Article

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