-
1
-
-
0034015682
-
Cytokine signaling: Regulation of the immune response in normal and critically ill states
-
Oberholzer, A., C. Oberholzer, and L. L. Moldawer. 2000. Cytokine signaling: regulation of the immune response in normal and critically ill states. Crit. Care Med. 28:N3.
-
(2000)
Crit. Care Med.
, vol.28
-
-
Oberholzer, A.1
Oberholzer, C.2
Moldawer, L.L.3
-
2
-
-
0001012615
-
TNF,IL-6, MIF and MIP-1 in inflammation
-
J. I. Gallin and R. Snyderman, eds. Lippincott-Raven, Philadelphia
-
Wang, H., and K. J. Tracey. 1999. TNF, IL-6, MIF and MIP-1 in inflammation. In Inflammation: Basic Principles and Clinical Correlates. J. I. Gallin and R. Snyderman, eds. Lippincott-Raven, Philadelphia, p. 471.
-
(1999)
Inflammation: Basic Principles and Clinical Correlates
, pp. 471
-
-
Wang, H.1
Tracey, K.J.2
-
3
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang, H., O. Bloom, M. Zhang, J. M. Vishnubhakat, M. Ombrellino, J. Che, A. Frazier, H. Yang, S. Ivanova, L. Borovikova, et al. 1999. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285:248.
-
(1999)
Science
, vol.285
, pp. 248
-
-
Wang, H.1
Bloom, O.2
Zhang, M.3
Vishnubhakat, J.M.4
Ombrellino, M.5
Che, J.6
Frazier, A.7
Yang, H.8
Ivanova, S.9
Borovikova, L.10
-
4
-
-
0035891570
-
HMGB1 as a late mediator of lethal systemic inflammation
-
Wang, H., H. Yang, C. J. Czura, A. E. Sama, and K. J. Tracey. 2001. HMGB1 as a late mediator of lethal systemic inflammation. Am. J. Respir. Crit. Care Med. 164:1768.
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
, pp. 1768
-
-
Wang, H.1
Yang, H.2
Czura, C.J.3
Sama, A.E.4
Tracey, K.J.5
-
5
-
-
0002606174
-
History, definitions and problems
-
E. W. Johns, ed. Academic, London
-
Johns, E. W. 1982. History, definitions and problems. In The HMG Chromosomal Proteins. E. W. Johns, ed. Academic, London. p. 1.
-
(1982)
The HMG Chromosomal Proteins
, pp. 1
-
-
Johns, E.W.1
-
6
-
-
0032814140
-
Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins
-
Bustin, M. 1999. Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol. Cell. Biol. 19:5237.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5237
-
-
Bustin, M.1
-
7
-
-
17144385352
-
HMGB1
-
A. Thomson and M. T. Lotze, eds. Academic, Oxford. In press
-
Wang, H., C. J. Czura, and K. J. Tracey. 2003. HMGB1. In The Cytokine Handbook. A. Thomson and M. T. Lotze, eds. Academic, Oxford. In press.
-
(2003)
The Cytokine Handbook
-
-
Wang, H.1
Czura, C.J.2
Tracey, K.J.3
-
8
-
-
0025994836
-
30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth: Amino acid sequence and localization in the filopodia of the advancing plasma membrane
-
Merenmies, J., R. Pihlaskari, J. Laitinen, J. Wartiovaara, and H. Rauvala. 1991. 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth: amino acid sequence and localization in the filopodia of the advancing plasma membrane. J. Biol. Chem. 266:16722.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16722
-
-
Merenmies, J.1
Pihlaskari, R.2
Laitinen, J.3
Wartiovaara, J.4
Rauvala, H.5
-
9
-
-
0034682315
-
Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases
-
Taguchi, A., D. C. Blood, G. del Toro, A. Canet, D. C. Lee, W. Qu, N. Tanji, Y. Lu, E. Lalla, C. Fu, et al. 2000. Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature 405:354.
-
(2000)
Nature
, vol.405
, pp. 354
-
-
Taguchi, A.1
Blood, D.C.2
Del Toro, G.3
Canet, A.4
Lee, D.C.5
Qu, W.6
Tanji, N.7
Lu, Y.8
Lalla, E.9
Fu, C.10
-
10
-
-
0028851635
-
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin: Mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system
-
Hori, O., J. Brett, T. Slattery, R. Cao, J. Zhang, J. X. Chen, M. Nagashima, E. R. Lundh, S. Vijay, and D. Nitecki. 1995. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin: mediation of neurite outgrowth and co-expression of RAGE and amphoterin in the developing nervous system. J. Biol. Chem. 270:25752.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25752
-
-
Hori, O.1
Brett, J.2
Slattery, T.3
Cao, R.4
Zhang, J.5
Chen, J.X.6
Nagashima, M.7
Lundh, E.R.8
Vijay, S.9
Nitecki, D.10
-
11
-
-
0035911959
-
The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
-
Degryse, B., T. Bonaldi, P. Scaffidi, S. Muller, M. Resnati, F. Sanvito, G. Arrigoni, and M. E. Bianchi. 2001. The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J. Cell Biol. 152:1197.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 1197
-
-
Degryse, B.1
Bonaldi, T.2
Scaffidi, P.3
Muller, S.4
Resnati, M.5
Sanvito, F.6
Arrigoni, G.7
Bianchi, M.E.8
-
12
-
-
0033598645
-
Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock
-
Ombrellino, M., H. Wang, M. S. Ajemian, A. Talhouk, L. A. Scher, S. G. Friedman, and K. J. Tracey. 1999. Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock. Lancet 354:1446.
-
(1999)
Lancet
, vol.354
, pp. 1446
-
-
Ombrellino, M.1
Wang, H.2
Ajemian, M.S.3
Talhouk, A.4
Scher, L.A.5
Friedman, S.G.6
Tracey, K.J.7
-
13
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi, P., T. Misteli, and M. E. Bianchi. 2002. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:191.
-
(2002)
Nature
, vol.418
, pp. 191
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
14
-
-
0036724929
-
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and causes derangements in intestinal barrier function in mice
-
Sappington, P. L., R. Yang, H. Yang, K. J. Tracey, R. L. Delude, and M. P. Fink. 2002. HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and causes derangements in intestinal barrier function in mice. Gastroenterology 123:790.
-
(2002)
Gastroenterology
, vol.123
, pp. 790
-
-
Sappington, P.L.1
Yang, R.2
Yang, H.3
Tracey, K.J.4
Delude, R.L.5
Fink, M.P.6
-
15
-
-
0034664791
-
HMG-1 as a mediator of acute lung inflammation
-
Abraham, E., J. Arcaroli, A. Carmody, H. Wang, and K. J. Tracey. 2000. HMG-1 as a mediator of acute lung inflammation. J. Immunol. 165:2950.
-
(2000)
J. Immunol.
, vol.165
, pp. 2950
-
-
Abraham, E.1
Arcaroli, J.2
Carmody, A.3
Wang, H.4
Tracey, K.J.5
-
16
-
-
0034698830
-
High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
-
Andersson, U., H. Wang, K. Palmblad, A. C. Aveberger, O. Bloom, H. Erlandsson-Harris, A. Janson, R. Kokkola, M. Zhang, H. Yang, and K. J. Tracey. 2000. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J. Exp. Med. 192:565.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 565
-
-
Andersson, U.1
Wang, H.2
Palmblad, K.3
Aveberger, A.C.4
Bloom, O.5
Erlandsson-Harris, H.6
Janson, A.7
Kokkola, R.8
Zhang, M.9
Yang, H.10
Tracey, K.J.11
-
17
-
-
0035997264
-
HMGB1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion
-
Agnello, D., H. Wang, H. Yang, K. J. Tracey, and P. Ghezzi. 2002. HMGB1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion. Cytokine 18:231.
-
(2002)
Cytokine
, vol.18
, pp. 231
-
-
Agnello, D.1
Wang, H.2
Yang, H.3
Tracey, K.J.4
Ghezzi, P.5
-
18
-
-
0037125985
-
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
-
Ulloa, L., M. Ochani, H. Yang, M. Tanovic, D. Halperin, R. Yang, C. J. Czura, M. P. Fink, and K. J. Tracey. 2002. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc. Natl. Acad. Sci. USA 99:12351.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12351
-
-
Ulloa, L.1
Ochani, M.2
Yang, H.3
Tanovic, M.4
Halperin, D.5
Yang, R.6
Czura, C.J.7
Fink, M.P.8
Tracey, K.J.9
-
19
-
-
0029011218
-
The MAPK signaling cascade
-
Seger, R., and E. G. Krebs. 1995. The MAPK signaling cascade. FASEB J. 9:726.
-
(1995)
FASEB J.
, vol.9
, pp. 726
-
-
Seger, R.1
Krebs, E.G.2
-
20
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha, M., and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cell. Signal. 13:85.
-
(2001)
Cell. Signal.
, vol.13
, pp. 85
-
-
Guha, M.1
Mackman, N.2
-
21
-
-
0025829450
-
Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: The effect of antiinflammatory agents
-
Martich, G. D., R. L. Danner, M. Ceska, and A. F. Suffredini. 1991. Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. J. Exp. Med. 173:1021.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1021
-
-
Martich, G.D.1
Danner, R.L.2
Ceska, M.3
Suffredini, A.F.4
-
22
-
-
0026056197
-
Blocking IL-1: Interleukin 1 receptor antagonist in vivo and in vitro
-
Dinarello, C. A., and R. C. Thompson. 1991. Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunol. Today 12:404.
-
(1991)
Immunol. Today
, vol.12
, pp. 404
-
-
Dinarello, C.A.1
Thompson, R.C.2
-
23
-
-
0036546350
-
Splenectomy ablates endotoxin-induced IFN-γ response in rats
-
Deriy, L. V., D. W. Beno, M. R. Uhing, V. A. Jiyamapa-Serna, and R. E. Kimura. 2002. Splenectomy ablates endotoxin-induced IFN-γ response in rats. Shock 17:312.
-
(2002)
Shock
, vol.17
, pp. 312
-
-
Deriy, L.V.1
Beno, D.W.2
Uhing, M.R.3
Jiyamapa-Serna, V.A.4
Kimura, R.E.5
-
24
-
-
0031001334
-
Mechanism of hepatocellular dysfunction during early sepsis: Key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6
-
Wang, P., Z. F. Ba, and I. H. Chaudry. 1997. Mechanism of hepatocellular dysfunction during early sepsis: key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6. Arch. Surg. 132:364.
-
(1997)
Arch. Surg.
, vol.132
, pp. 364
-
-
Wang, P.1
Ba, Z.F.2
Chaudry, I.H.3
-
25
-
-
0027442237
-
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
-
Bernhagen, J., T. Calandra, R. A. Mitchell, S. B. Martin, K. J. Tracey, W. Voelter, K. R. Manogue, A. Cerami, and R. Bucala. 1993. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 365:756.
-
(1993)
Nature
, vol.365
, pp. 756
-
-
Bernhagen, J.1
Calandra, T.2
Mitchell, R.A.3
Martin, S.B.4
Tracey, K.J.5
Voelter, W.6
Manogue, K.R.7
Cerami, A.8
Bucala, R.9
-
26
-
-
0001611329
-
Protection from septic shock by neutralization of macrophage migration inhibitory factor
-
Calandra, T., B. Echtenacher, D. L. Roy, J. Pugin, C. N. Metz, L. Hultner, D. Heumann, D. Mannel, R. Bucala, and M. P. Glauser. 2000. Protection from septic shock by neutralization of macrophage migration inhibitory factor. Nat. Med. 6:164.
-
(2000)
Nat. Med.
, vol.6
, pp. 164
-
-
Calandra, T.1
Echtenacher, B.2
Roy, D.L.3
Pugin, J.4
Metz, C.N.5
Hultner, L.6
Heumann, D.7
Mannel, D.8
Bucala, R.9
Glauser, M.P.10
-
27
-
-
0033579884
-
Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis
-
Bozza, M., A. R. Satoskar, G. Lin, B. Lu, A. A. Humbles, C. Gerard, and J. R. David. 1999. Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. J. Exp. Med. 189:341.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 341
-
-
Bozza, M.1
Satoskar, A.R.2
Lin, G.3
Lu, B.4
Humbles, A.A.5
Gerard, C.6
David, J.R.7
-
28
-
-
0023793266
-
Modulation of major histocompatibility complex (MHC) expression by interferons and microbial agents: Independent regulation of MHC class II expression and induction of tumoricidal activity in bone marrow-derived mononuclear phagocytes
-
Keller, R., P. Joller, R. Keist, H. Binz, and P. H. van der Meide. 1988. Modulation of major histocompatibility complex (MHC) expression by interferons and microbial agents: independent regulation of MHC class II expression and induction of tumoricidal activity in bone marrow-derived mononuclear phagocytes. Scand. J. Immunol. 28:113.
-
(1988)
Scand. J. Immunol.
, vol.28
, pp. 113
-
-
Keller, R.1
Joller, P.2
Keist, R.3
Binz, H.4
Van der Meide, P.H.5
-
29
-
-
0025141256
-
Interferon-γ drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells
-
Ucla, C., P. Roux-Lombard, S. Fey, J. M. Dayer, and B. Mach. 1990. Interferon-γ drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells. J. Clin. Invest. 85:185.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 185
-
-
Ucla, C.1
Roux-Lombard, P.2
Fey, S.3
Dayer, J.M.4
Mach, B.5
-
30
-
-
0030890586
-
Cellular responses to interferon-γ
-
Boehm, U., T. Klamp, M. Groot, and J. C. Howard. 1997. Cellular responses to interferon-γ. Annu. Rev. Immunol. 15:749.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 749
-
-
Boehm, U.1
Klamp, T.2
Groot, M.3
Howard, J.C.4
-
31
-
-
0023032728
-
Effect of γ-interferon on cachectin expression by mononuclear phagocytes: Reversal of the lpsd (endotoxin resistance) phenotype
-
Beutler, B., V. Tkacenko, I. Milsark, N. Krochin, and A. Cerami. 1986. Effect of γ-interferon on cachectin expression by mononuclear phagocytes: reversal of the lpsd (endotoxin resistance) phenotype. J. Exp. Med. 164:1791.
-
(1986)
J. Exp. Med.
, vol.164
, pp. 1791
-
-
Beutler, B.1
Tkacenko, V.2
Milsark, I.3
Krochin, N.4
Cerami, A.5
-
32
-
-
0028270957
-
Interferon-γ increases mortality following cecal ligation and puncture
-
Miles, R. H., T. P. Paxton, D. J. Dries, and R. L. Gamelli. 1994. Interferon-γ increases mortality following cecal ligation and puncture. J. Trauma 36:607.
-
(1994)
J. Trauma
, vol.36
, pp. 607
-
-
Miles, R.H.1
Paxton, T.P.2
Dries, D.J.3
Gamelli, R.L.4
-
33
-
-
0026661026
-
Evidence for IFN-γ as a mediator of the lethality of endotoxin and tumor necrosis factor-α
-
Doherty, G. M., J. R. Lange, H. N. Langstein, H. R. Alexander, C. M. Buresh, and J. A. Norton. 1992. Evidence for IFN-γ as a mediator of the lethality of endotoxin and tumor necrosis factor-α. J. Immunol. 149:1666.
-
(1992)
J. Immunol.
, vol.149
, pp. 1666
-
-
Doherty, G.M.1
Lange, J.R.2
Langstein, H.N.3
Alexander, H.R.4
Buresh, C.M.5
Norton, J.A.6
-
34
-
-
0025134961
-
The role of IFN-γ in the pathology of experimental endotoxemia
-
Heinzel, F. P. 1990. The role of IFN-γ in the pathology of experimental endotoxemia. J. Immunol. 145:2920.
-
(1990)
J. Immunol.
, vol.145
, pp. 2920
-
-
Heinzel, F.P.1
-
35
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-γ genes
-
Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739.
-
(1993)
Science
, vol.259
, pp. 1739
-
-
Dalton, D.K.1
Pitts-Meek, S.2
Keshav, S.3
Figari, I.S.4
Bradley, A.5
Stewart, T.A.6
-
36
-
-
0030467174
-
A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection
-
Newport, M. J., C. M. Huxley, S. Huston, C. M. Hawrylowicz, B. A. Oostra, R. Williamson, and M. Levin. 1996. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection. N. Engl. J. Med. 335:1941.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1941
-
-
Newport, M.J.1
Huxley, C.M.2
Huston, S.3
Hawrylowicz, C.M.4
Oostra, B.A.5
Williamson, R.6
Levin, M.7
-
37
-
-
0028222122
-
Interferon-γ receptor deficient mice are resistant to endotoxic shock
-
Car, B. D., V. M. Eng, B. Schnyder, L. Ozmen, S. Huang, P. Gallay, D. Heumann, M. Aguet, and B. Ryffel. 1994. Interferon-γ receptor deficient mice are resistant to endotoxic shock. J. Exp. Med. 179:1437.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1437
-
-
Car, B.D.1
Eng, V.M.2
Schnyder, B.3
Ozmen, L.4
Huang, S.5
Gallay, P.6
Heumann, D.7
Aguet, M.8
Ryffel, B.9
-
39
-
-
0034254991
-
Spinophilin regulates the formation and function of dendritic spines
-
Feng, J., Z. Yan, A. Ferreira, K. Tomizawa, J. A. Liauw, M. Zhuo, P. B. Allen, C. C. Ouimet, and P. Greengard. 2000. Spinophilin regulates the formation and function of dendritic spines. Proc. Natl. Acad. Sci. USA 97:9287.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9287
-
-
Feng, J.1
Yan, Z.2
Ferreira, A.3
Tomizawa, K.4
Liauw, J.A.5
Zhuo, M.6
Allen, P.B.7
Ouimet, C.C.8
Greengard, P.9
-
40
-
-
0030965838
-
Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counterregulatory mechanism that restrains the immune response
-
Zhang, M., T. Caragine, H. Wang, P. S. Cohen, G. Botchkina, K. Soda, M. Bianchi, P. Ulrich, A. Cerami, B. Sherry, and K. J. Tracey. 1997. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. J. Exp. Med. 185: 1759.
-
(1997)
J. Exp. Med
, vol.185
, pp. 1759
-
-
Zhang, M.1
Caragine, T.2
Wang, H.3
Cohen, P.S.4
Botchkina, G.5
Soda, K.6
Bianchi, M.7
Ulrich, P.8
Cerami, A.9
Sherry, B.10
Tracey, K.J.11
-
41
-
-
0029258451
-
An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality
-
Bianchi, M., P. Ulrich, O. Bloom, M. Meistrell, G. A. Zimmerman, H. Schmidtmayerova, M. Bukrinsky, T. Donnelley, R. Bucala, and B. Sherry. 1995. An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality. Mol. Med. 1:254.
-
(1995)
Mol. Med.
, vol.1254
-
-
Bianchi, M.1
Ulrich, P.2
Bloom, O.3
Meistrell, M.4
Zimmerman, G.A.5
Schmidtmayerova, H.6
Bukrinsky, M.7
Donnelley, T.8
Bucala, R.9
Sherry, B.10
-
42
-
-
0036142395
-
Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease
-
Hommes, D., B. van den Blink, T. Plasse, J. Bartelsman, C. Xu, B. Macpherson, G. Tytgat, M. Peppelenbosch, and S. Van Deventer. 2002. Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease. Gastroenterology 122:7.
-
(2002)
Gastroenterology
, vol.122
, pp. 7
-
-
Hommes, D.1
Van Den Blink, B.2
Plasse, T.3
Bartelsman, J.4
Xu, C.5
Macpherson, B.6
Tytgat, G.7
Peppelenbosch, M.8
Van Deventer, S.9
-
43
-
-
0034658583
-
Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
-
Kotenko, S. V., and S. Pestka. 2000. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19:2557.
-
(2000)
Oncogene
, vol.19
, pp. 2557
-
-
Kotenko, S.V.1
Pestka, S.2
-
44
-
-
0033563170
-
Tyrphostin B42 inhibits IL-12-induced tyrosine phosphorylation and activation of Janus kinase-2 and prevents experimental allergic encephalomyelitis
-
Bright, J. J., C. Du, and S. Sriram. 1999. Tyrphostin B42 inhibits IL-12-induced tyrosine phosphorylation and activation of Janus kinase-2 and prevents experimental allergic encephalomyelitis. J. Immunol. 162:6255.
-
(1999)
J. Immunol.
, vol.162
, pp. 6255
-
-
Bright, J.J.1
Du, C.2
Sriram, S.3
-
45
-
-
0036775236
-
The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
-
955.5
-
Gardella, S., C. Andrei, D. Ferrera, L. V. Lotti, M. R. Torrisi, M. E. Bianchi, and A. Rubartelli. 2002. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep. 3:955.5.
-
(2002)
EMBO Rep.
, vol.3
-
-
Gardella, S.1
Andrei, C.2
Ferrera, D.3
Lotti, L.V.4
Torrisi, M.R.5
Bianchi, M.E.6
Rubartelli, A.7
-
46
-
-
0021885782
-
γ-interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis
-
Robinson, B. W., T. L. McLemore, and R. G. Crystal. 1985. γ-Interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis. J. Clin. Invest. 75:1488.
-
(1985)
J. Clin. Invest.
, vol.75
, pp. 1488
-
-
Robinson, B.W.1
McLemore, T.L.2
Crystal, R.G.3
-
47
-
-
0027366571
-
Induction of IFN-γ in macrophages by lipopolysaccharide
-
Fultz, M. J., S. A. Barber, C. W. Dieffenbach, and S. N. Vogel. 1993. Induction of IFN-γ in macrophages by lipopolysaccharide. Int. Immunol. 5:1383.
-
(1993)
Int. Immunol.
, vol.5
, pp. 1383
-
-
Fultz, M.J.1
Barber, S.A.2
Dieffenbach, C.W.3
Vogel, S.N.4
-
48
-
-
0025942326
-
Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation: Role of IFN-γ in the induction of the nitric oxide-synthesizing pathway
-
Albina, J. E., J. A. Abate, and W. L. Henry, Jr. 1991. Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation: role of IFN-γ in the induction of the nitric oxide-synthesizing pathway. J. Immunol. 147:144.
-
(1991)
J. Immunol.
, vol.14
, pp. 7144
-
-
Albina, J.E.1
Abate, J.A.2
Henry W.L., Jr.3
-
49
-
-
0026575339
-
IFN-γ-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-α
-
Langermans, J. A., M. E. Van der Hulst, P. H. Nibbering, P. S. Hiemstra, L. Fransen, and R. Van Furth. 1992. IFN-γ-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-α. J. Immunol. 148:568.
-
(1992)
J. Immunol.
, vol.148
, pp. 568
-
-
Langermans, J.A.1
Van der Hulst, M.E.2
Nibbering, P.H.3
Hiemstra, P.S.4
Fransen, L.5
Van Furth, R.6
-
50
-
-
0035904232
-
S-Nitrosylation of mitochondrial caspases
-
Mannick, J. B., C. Schonhoff, N. Papeta, P. Ghafourifar, M. Szibor, K. Fang, and B. Gaston. 2001. S-Nitrosylation of mitochondrial caspases. J. Cell Biol. 154:1111.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 1111
-
-
Mannick, J.B.1
Schonhoff, C.2
Papeta, N.3
Ghafourifar, P.4
Szibor, M.5
Fang, K.6
Gaston, B.7
-
51
-
-
0032526891
-
Blockade of endogenous TNF-α exacerbates primary and secondary pulmonary histoplasmosis by differential mechanisms
-
Allendoerfer, R., and G. S. Deepe, Jr. 1998. Blockade of endogenous TNF-α exacerbates primary and secondary pulmonary histoplasmosis by differential mechanisms. J. Immunol. 160:6072.
-
(1998)
J. Immunol.
, vol.160
, pp. 6072
-
-
Allendoerfer, R.1
Deepe G.S., Jr.2
-
52
-
-
0347816925
-
TNF
-
A. Thomson and M. T. Lotze, eds. Academic, Oxford. In Press
-
Czura, C. J., H. Wang, and K. J. Tracey. 2003. TNF. In The Cytokine Handbook. A. Thomson and M. T. Lotze, eds. Academic, Oxford. In Press.
-
(2003)
The Cytokine Handbook
-
-
Czura, C.J.1
Wang, H.2
Tracey, K.J.3
-
53
-
-
0036822347
-
High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis
-
Kokkola, R., E. Sundberg, A. K. Ulfgren, K. Palmblad, J. Li, H. Wang, L. Ulloa, H. Yang, X. J. Yan, N. Chiorazzi, et al. 2002. High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. Arthritis Rheum. 46:2598.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2598
-
-
Kokkola, R.1
Sundberg, E.2
Ulfgren, A.K.3
Palmblad, K.4
Li, J.5
Wang, H.6
Ulloa, L.7
Yang, H.8
Yan, X.J.9
Chiorazzi, N.10
-
54
-
-
0034045949
-
Inhibition of p38 MAP kinase as a therapeutic strategy
-
Lee, J. C., S. Kumar, D. E. Griswold, D. C. Underwood, B. J. Votta, and J. L. Adams. 2000. Inhibition of p38 MAP kinase as a therapeutic strategy. Immunopharmacology 47:185.
-
(2000)
Immunopharmacology
, vol.47
, pp. 185
-
-
Lee, J.C.1
Kumar, S.2
Griswold, D.E.3
Underwood, D.C.4
Votta, B.J.5
Adams, J.L.6
-
55
-
-
0035000643
-
Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers
-
Fijen, J. W., J. G. Zijlstra, P. De Boer, R. Spanjersberg, T. J. Cohen, T. S. Van Der Werf, J. J. Ligtenberg, and J. E. Tulleken. 2001. Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers. Clin. Exp. Immunol. 124:16.
-
(2001)
Clin. Exp. Immunol.
, vol.124
, pp. 16
-
-
Fijen, J.W.1
Zijlstra, J.G.2
De Boer, P.3
Spanjersberg, R.4
Cohen, T.J.5
Van Der Werf, T.S.6
Ligtenberg, J.J.7
Tulleken, J.E.8
-
56
-
-
0035229054
-
Evolution of an immune suppressive macrophage phenotype as a product of p38 MAPK activation in polymicrobial sepsis
-
Song, G. Y., C. S. Chung, D. Jarrar, I. H. Chaudry, and A. Ayala. 2001. Evolution of an immune suppressive macrophage phenotype as a product of p38 MAPK activation in polymicrobial sepsis. Shock 15:42.
-
(2001)
Shock
, vol.15
, pp. 42
-
-
Song, G.Y.1
Chung, C.S.2
Jarrar, D.3
Chaudry, I.H.4
Ayala, A.5
-
57
-
-
0034121690
-
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis
-
Badger, A. M., D. E. Griswold, R. Kapadia, S. Blake, B. A. Swift, S. J. Hoffman, G. B. Stroup, E. Webb, D. J. Rieman, M. Gowen, et al. 2000. Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis. Arthritis Rheum. 43:175.
-
(2000)
Arthritis Rheum.
, vol.43
, pp. 175
-
-
Badger, A.M.1
Griswold, D.E.2
Kapadia, R.3
Blake, S.4
Swift, B.A.5
Hoffman, S.J.6
Stroup, G.B.7
Webb, E.8
Rieman, D.J.9
Gowen, M.10
-
58
-
-
13844288120
-
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung
-
Underwood, D. C., R. R. Osborn, S. Bochnowicz, E. F. Webb, D. J. Rieman, J. C. Lee, A. M. Romanic, J. L. Adams, D. W. Hay, and D. E. Griswold. 2000. SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am. J. Physiol. 279:L895.
-
(2000)
Am. J. Physiol.
, vol.279
-
-
Underwood, D.C.1
Osborn, R.R.2
Bochnowicz, S.3
Webb, E.F.4
Rieman, D.J.5
Lee, J.C.6
Romanic, A.M.7
Adams, J.L.8
Hay, D.W.9
Griswold, D.E.10
-
59
-
-
0035142857
-
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia
-
Barone, F. C., E. A. Irving, A. M. Ray, J. C. Lee, S. Kassis, S. Kumar, A. M. Badger, R. F. White, M. J. McVey, J. J. Legos, et al. 2001. SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J. Pharmacol. Exp. Ther. 296:312.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.29
, pp. 6312
-
-
Barone, F.C.1
Irving, E.A.2
Ray, A.M.3
Lee, J.C.4
Kassis, S.5
Kumar, S.6
Badger, A.M.7
White, R.F.8
McVey, M.J.9
Legos, J.J.10
-
60
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea, J. J., M. Gadina, and R. D. Schreiber. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109(Suppl):S121.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
61
-
-
0028979707
-
Stat recruitment by tyrosine-phosphorylated cytokine receptors: An ordered reversible affinity-driven process
-
Greenlund, A. C., M. O. Morales, B. L. Viviano, H. Yan, J. Krolewski, and R. D. Schreiber. 1995. Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. Immunity 2:677.
-
(1995)
Immunity
, vol.2
, pp. 677
-
-
Greenlund, A.C.1
Morales, M.O.2
Viviano, B.L.3
Yan, H.4
Krolewski, J.5
Schreiber, R.D.6
-
62
-
-
0032547850
-
Interferon induction of TAP1: The phosphatase SHP-1 regulates crossover between the IFN-α/β and the IFN-γ signal-transduction pathways
-
Min, W., J. S. Pober, and D. R. Johnson. 1998. Interferon induction of TAP1: the phosphatase SHP-1 regulates crossover between the IFN-α/β and the IFN-γ signal-transduction pathways. Circ. Res. 83:815.
-
(1998)
Circ. Res.
, vol.83
, pp. 815
-
-
Min, W.1
Pober, J.S.2
Johnson, D.R.3
-
63
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E. J., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415.
-
(1994)
Science
, vol.264
, pp. 1415
-
-
Darnell, J.E.J.1
Kerr, I.M.2
Stark, G.R.3
-
64
-
-
0034120709
-
IFN regulatory factor-I-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-I gene promoter by IFN-γ
-
Saito H., Y. Morita, M. Fujimoto, M. Narazaki, T. Naka, and T. Kishimoto. 2000. IFN regulatory factor-I-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-I gene promoter by IFN-γ. J. Immunol. 164:5833.
-
(2000)
J. Immunol.
, vol.164
, pp. 5833
-
-
Saito, H.1
Morita, Y.2
Fujimoto, M.3
Narazaki, M.4
Naka, T.5
Kishimoto, T.6
-
65
-
-
0036889113
-
The role of IFN-γ in immune responses to viral infections of the central nervous system
-
Chesler, D. A., and C. S. Reiss. 2002. The role of IFN-γ in immune responses to viral infections of the central nervous system. Cytokine Growth Factor Rev. 13:441.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 441
-
-
Chesler, D.A.1
Reiss, C.S.2
-
66
-
-
0032076183
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
-
Rodig, S. J., M. A. Meraz, J. M. White, P. A. Lampe, J. K. Riley, C. D. Arthur, K. L. King, K. C. Sheehan, L. Yin, D. Pennica, et al. 1998. Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93:373.
-
(1998)
Cell
, vol.93
, pp. 373
-
-
Rodig, S.J.1
Meraz, M.A.2
White, J.M.3
Lampe, P.A.4
Riley, J.K.5
Arthur, C.D.6
King, K.L.7
Sheehan, K.C.8
Yin, L.9
Pennica, D.10
-
67
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas, E., D. Wang, D. Stravopodis, D. J. Topham, J. C. Marine, S. Teglund, E. F. Vanin, S. Bodner, O. R. Colamonici, J. M. van Deursen, et al. 1998. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93:385.
-
(1998)
Cell
, vol.93
, pp. 385
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
Topham, D.J.4
Marine, J.C.5
Teglund, S.6
Vanin, E.F.7
Bodner, S.8
Colamonici, O.R.9
Van Deursen, J.M.10
-
68
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A., J. M: White, K. C. Sheehan, E. A. Bach, S. J. Rodig, A. S. Dighe, D. H. Kaplan, J. K. Riley, A. C. Greenlund, D. Campbell, et al. 1996. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84:431.
-
(1996)
Cell
, vol.84
, pp. 431
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
-
69
-
-
0032719182
-
Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-γ (IFN-γ)
-
Ochiai, K., E. Tanabe, C. Ishihara, M. Kagami, T. Sugiyama, M. Sueishi, N. Koya, and H. Tomioka. 1999. Role of JAK2 signal transductional pathway in activation and survival of human peripheral eosinophils by interferon-γ (IFN-γ). Clin. Exp. Immunol. 118:340.
-
(1999)
Clin. Exp. Immunol.
, vol.118
, pp. 340
-
-
Ochiai, K.1
Tanabe, E.2
Ishihara, C.3
Kagami, M.4
Sugiyama, T.5
Sueishi, M.6
Koya, N.7
Tomioka, H.8
-
70
-
-
0033061032
-
Protein tyrosine kinase inhibitors as novel therapeutic agents
-
Levitzki, A. 1999. Protein tyrosine kinase inhibitors as novel therapeutic agents. Pharmacol. Ther. 82:231.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 231
-
-
Levitzki, A.1
|