Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice

Phytotherapy Research

Volumn 26, Issue 4, 2012, Pages 605-612

  Jun, Min Soo ^a   Kim, Hee Sook ^a   Kim, Young Min ^a   Kim, Hye Jung ^a   Park, Eun Jung ^a   Lee, Jae Heun ^a   Lee, Kang Ro ^b   Kim, Yeong Shik ^c   Chang, Ki Churl ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

antiinflammation; HMGB1; HO 1; NF B; Nrf2; Prunella vulgaris var. lilacina

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOOXYGENASE 2; HEME OXYGENASE 1; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PRUNELLA VULGARIS EXTRACT; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CECUM; CONTROLLED STUDY; DRUG ISOLATION; ENZYME INDUCTION; EXPERIMENTAL LIGATION; FLOWER; IN VIVO STUDY; LUNG; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PHYTOCHEMISTRY; PROSTAGLANDIN SYNTHESIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TRANSPORT; SEPSIS;

ANIMALS; ANTHRACENES; CECUM; CELL LINE; CELL SURVIVAL; CHROMONES; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; ENZYME INDUCTION; ETHANOL; FLAVONOIDS; FLOWERS; GENETIC VECTORS; HEME OXYGENASE-1; HMGB1 PROTEIN; IMIDAZOLES; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MORPHOLINES; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PROTEIN TRANSPORT; PRUNELLA; PYRIDINES; SEPSIS; SIGNAL TRANSDUCTION; TRANSFECTION;

EUROPEAN ELK PAPILLOMAVIRUS; MUS; PRUNELLA VULGARIS;

EID: 84859621252     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3613     Document Type: Article

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