메뉴 건너뛰기




Volumn 1845, Issue 2, 2014, Pages 232-247

The role of key genes and pathways involved in the tumorigenesis of Malignant Mesothelioma

Author keywords

Erionite SV40; Genes and pathways; Malignant Mesothelioma; NF2; PI3K AKT

Indexed keywords

ASBESTOS; BRCA1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; NEUROFIBROMATOSIS TYPE 2 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P14; RAF PROTEIN; RAS PROTEIN; SMOOTHENED PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84894044731     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2014.01.008     Document Type: Review
Times cited : (51)

References (252)
  • 1
    • 27144548037 scopus 로고    scopus 로고
    • Mesothelioma: time to take stock
    • Tan C., Treasure T. Mesothelioma: time to take stock. J. R. Soc. Med. 2005, 98:455-458.
    • (2005) J. R. Soc. Med. , vol.98 , pp. 455-458
    • Tan, C.1    Treasure, T.2
  • 2
    • 34247158183 scopus 로고    scopus 로고
    • Asbestos-related diseases of the lungs and pleura: uses, trends and management over the last century
    • Becklake M.R., Bagatin E., Neder J.A. Asbestos-related diseases of the lungs and pleura: uses, trends and management over the last century. Int. J. Tuberc. Lung Dis. 2007, 11:356-369.
    • (2007) Int. J. Tuberc. Lung Dis. , vol.11 , pp. 356-369
    • Becklake, M.R.1    Bagatin, E.2    Neder, J.A.3
  • 3
    • 84858663671 scopus 로고    scopus 로고
    • Mesothelioma: a review
    • Mott F.E. Mesothelioma: a review. Ochsner J. 2012, 12:70-79.
    • (2012) Ochsner J. , vol.12 , pp. 70-79
    • Mott, F.E.1
  • 4
    • 79955031861 scopus 로고    scopus 로고
    • Genetics and molecular biology of mesothelioma
    • Springer, Berlin Heidelberg
    • Fennell D.A. Genetics and molecular biology of mesothelioma. Malignant Mesothelioma 2012, vol. 189:149-167. Springer, Berlin Heidelberg.
    • (2012) Malignant Mesothelioma , vol.189 , pp. 149-167
    • Fennell, D.A.1
  • 5
    • 58149092839 scopus 로고    scopus 로고
    • Mesothelioma epidemiology, carcinogenesis, and pathogenesis
    • Yang H., Testa J., Carbone M. Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr. Treat. Options in Oncol. 2008, 9:147-157.
    • (2008) Curr. Treat. Options in Oncol. , vol.9 , pp. 147-157
    • Yang, H.1    Testa, J.2    Carbone, M.3
  • 6
    • 27244447448 scopus 로고    scopus 로고
    • Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada
    • van Meerbeeck J.P., Gaafar R., Manegold C., Van Klaveren R.J., Van Marck E.A., Vincent M., Legrand C., Bottomley A., Debruyne C., Giaccone G. Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada. J. Clin. Oncol. 2005, 23:6881-6889.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 6881-6889
    • van Meerbeeck, J.P.1    Gaafar, R.2    Manegold, C.3    Van Klaveren, R.J.4    Van Marck, E.A.5    Vincent, M.6    Legrand, C.7    Bottomley, A.8    Debruyne, C.9    Giaccone, G.10
  • 7
    • 84910467774 scopus 로고
    • Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province
    • Wagner J.C., Sleggs C.A., Marchand P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br. J. Ind. Med. 1960, 17:260-271.
    • (1960) Br. J. Ind. Med. , vol.17 , pp. 260-271
    • Wagner, J.C.1    Sleggs, C.A.2    Marchand, P.3
  • 10
    • 0027092289 scopus 로고
    • Intrapleural administration of fibres induces mesothelioma in rats in the same relative order of hazard as occurs in man after exposure
    • Carthew P., Hill R., Edwards R., Lee P. Intrapleural administration of fibres induces mesothelioma in rats in the same relative order of hazard as occurs in man after exposure. Hum. Exp. Toxicol. 1992, 11:530-534.
    • (1992) Hum. Exp. Toxicol. , vol.11 , pp. 530-534
    • Carthew, P.1    Hill, R.2    Edwards, R.3    Lee, P.4
  • 14
    • 20444411897 scopus 로고    scopus 로고
    • Implications of P16/CDKN2A deletion in pleural mesotheliomas
    • (Amsterdam, Netherlands)
    • Ladanyi M. Implications of P16/CDKN2A deletion in pleural mesotheliomas. Lung Cancer 2005, 49:S95-S98. (Amsterdam, Netherlands).
    • (2005) Lung Cancer , vol.49
    • Ladanyi, M.1
  • 17
    • 84870524947 scopus 로고    scopus 로고
    • From tumor prevention to therapy: empowering p53 to fight back
    • Frezza C., Martins C.P. From tumor prevention to therapy: empowering p53 to fight back. Drug Resist. Updat. 2012, 15:258-267.
    • (2012) Drug Resist. Updat. , vol.15 , pp. 258-267
    • Frezza, C.1    Martins, C.P.2
  • 18
    • 71849098457 scopus 로고    scopus 로고
    • Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells
    • Sekido Y. Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells. Cancer Sci. 2009, 101:1-6.
    • (2009) Cancer Sci. , vol.101 , pp. 1-6
    • Sekido, Y.1
  • 21
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T., Dixon J.E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 1998, 273:13375-13378.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 27
    • 34247146844 scopus 로고    scopus 로고
    • Update on the molecular biology of malignant mesothelioma
    • Lee A.Y., Raz D.J., He B., Jablons D.M. Update on the molecular biology of malignant mesothelioma. Cancer 2007, 109:1454-1461.
    • (2007) Cancer , vol.109 , pp. 1454-1461
    • Lee, A.Y.1    Raz, D.J.2    He, B.3    Jablons, D.M.4
  • 28
    • 33750313674 scopus 로고    scopus 로고
    • EGFR expression: associations with outcome and clinicopathological variables in malignant pleural mesothelioma
    • (Amsterdam, Netherlands)
    • Edwards J.G., Swinson D.E.B., Jones J.L., Waller D.A., O'Byrne K.J. EGFR expression: associations with outcome and clinicopathological variables in malignant pleural mesothelioma. Lung Cancer 2006, 54:399-407. (Amsterdam, Netherlands).
    • (2006) Lung Cancer , vol.54 , pp. 399-407
    • Edwards, J.G.1    Swinson, D.E.B.2    Jones, J.L.3    Waller, D.A.4    O'Byrne, K.J.5
  • 29
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86:353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 31
    • 3142731985 scopus 로고    scopus 로고
    • Moving beyond chemotherapy: novel cytostatic agents for malignant mesothelioma
    • (Amsterdam, Netherlands)
    • Kindler H.L. Moving beyond chemotherapy: novel cytostatic agents for malignant mesothelioma. Lung Cancer 2004, 45:S125-S127. (Amsterdam, Netherlands).
    • (2004) Lung Cancer , vol.45
    • Kindler, H.L.1
  • 33
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: progress and puzzles
    • Lowe S.W., Sherr C.J. Tumor suppression by Ink4a-Arf: progress and puzzles. Curr. Opin. Genet. Dev. 2003, 13:77-83.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 35
    • 0032758427 scopus 로고    scopus 로고
    • Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma
    • Soini Y., Kinnula V., Kaarteenaho-Wiik R., Kurttila E., Linnainmaa K., Pääkkö P. Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma. Clin. Cancer Res. 1999, 5:3508-3515.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3508-3515
    • Soini, Y.1    Kinnula, V.2    Kaarteenaho-Wiik, R.3    Kurttila, E.4    Linnainmaa, K.5    Pääkkö, P.6
  • 37
    • 84874257648 scopus 로고    scopus 로고
    • The Hippo pathway: regulators and regulations
    • Yu F.-X., Guan K.-L. The Hippo pathway: regulators and regulations. Genes Dev. 2013, 27:355-371.
    • (2013) Genes Dev. , vol.27 , pp. 355-371
    • Yu, F.-X.1    Guan, K.-L.2
  • 42
    • 84894030900 scopus 로고    scopus 로고
    • The function, mechanisms, and role of the genes PTEN and TP53 and the effects of asbestos in the development of malignant mesothelioma: a review focused on the genes' molecular mechanisms
    • de Assis L.V., Isoldi M.C. The function, mechanisms, and role of the genes PTEN and TP53 and the effects of asbestos in the development of malignant mesothelioma: a review focused on the genes' molecular mechanisms. Tumor Biol. 2013, 1-13.
    • (2013) Tumor Biol. , pp. 1-13
    • de Assis, L.V.1    Isoldi, M.C.2
  • 44
    • 0042968914 scopus 로고    scopus 로고
    • New developments about the association of SV40 with human mesothelioma
    • Carbone M., Pass H.I., Miele L., Bocchetta M. New developments about the association of SV40 with human mesothelioma. Oncogene 2003, 22:5173-5180.
    • (2003) Oncogene , vol.22 , pp. 5173-5180
    • Carbone, M.1    Pass, H.I.2    Miele, L.3    Bocchetta, M.4
  • 46
    • 4644231356 scopus 로고    scopus 로고
    • Evidence against a role for SV40 infection in human mesotheliomas and high risk of false-positive PCR results owing to presence of SV40 sequences in common laboratory plasmids
    • Lopez-Rios F., Illei P.B., Rusch V., Ladanyi M. Evidence against a role for SV40 infection in human mesotheliomas and high risk of false-positive PCR results owing to presence of SV40 sequences in common laboratory plasmids. Lancet 2004, 364:1157-1166.
    • (2004) Lancet , vol.364 , pp. 1157-1166
    • Lopez-Rios, F.1    Illei, P.B.2    Rusch, V.3    Ladanyi, M.4
  • 48
    • 0036119472 scopus 로고    scopus 로고
    • Reappraisal of the strong association between simian virus 40 and human malignant mesothelioma of the pleura (Belgium)
    • Hubner R., Van Marck E. Reappraisal of the strong association between simian virus 40 and human malignant mesothelioma of the pleura (Belgium). Cancer Causes Control 2002, 13:121-129.
    • (2002) Cancer Causes Control , vol.13 , pp. 121-129
    • Hubner, R.1    Van Marck, E.2
  • 50
    • 78650455185 scopus 로고    scopus 로고
    • No implication of Simian virus 40 in pathogenesis of malignant pleural mesothelioma in Slovenia
    • Hmeljak J., Kern I., Cör A. No implication of Simian virus 40 in pathogenesis of malignant pleural mesothelioma in Slovenia. Tumori 2010, 96:667-673.
    • (2010) Tumori , vol.96 , pp. 667-673
    • Hmeljak, J.1    Kern, I.2    Cör, A.3
  • 51
    • 80053369730 scopus 로고    scopus 로고
    • Simian virus 40 transformation, malignant mesothelioma and brain tumors
    • Qi F., Carbone M., Yang H., Gaudino G. Simian virus 40 transformation, malignant mesothelioma and brain tumors. Expert Rev. Respir. Med. 2012, 5:683-697.
    • (2012) Expert Rev. Respir. Med. , vol.5 , pp. 683-697
    • Qi, F.1    Carbone, M.2    Yang, H.3    Gaudino, G.4
  • 52
    • 0027764515 scopus 로고
    • SV40 induces mesotheliomas in hamsters
    • Cicala C., Pompetti F., Carbone M. SV40 induces mesotheliomas in hamsters. Am. J. Pathol. 1993, 142:1524-1533.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1524-1533
    • Cicala, C.1    Pompetti, F.2    Carbone, M.3
  • 54
    • 84893411845 scopus 로고    scopus 로고
    • Long-term exposure of mesothelial cells to SV40 and asbestos leads to malignant transformation and chemotherapy resistance
    • Cleaver A.L., Bhamidipaty K., Wylie B., Connor T., Robinson C., Robinson B.W., Mutsaers S.E., Lake R.A. Long-term exposure of mesothelial cells to SV40 and asbestos leads to malignant transformation and chemotherapy resistance. Carcinogenesis 2013, 35(2):407-414.
    • (2013) Carcinogenesis , vol.35 , Issue.2 , pp. 407-414
    • Cleaver, A.L.1    Bhamidipaty, K.2    Wylie, B.3    Connor, T.4    Robinson, C.5    Robinson, B.W.6    Mutsaers, S.E.7    Lake, R.A.8
  • 55
    • 0037427078 scopus 로고    scopus 로고
    • Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells
    • Bocchetta M., Miele L., Pass H., Carbone M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene 2003, 22:81-89.
    • (2003) Oncogene , vol.22 , pp. 81-89
    • Bocchetta, M.1    Miele, L.2    Pass, H.3    Carbone, M.4
  • 56
    • 39449104247 scopus 로고    scopus 로고
    • The SV40 large T antigen-p53 complexes bind and activate the insulin-like growth factor-I promoter stimulating cell growth
    • Bocchetta M., Eliasz S., De Marco M.A., Rudzinski J., Zhang L., Carbone M. The SV40 large T antigen-p53 complexes bind and activate the insulin-like growth factor-I promoter stimulating cell growth. Cancer Res. 2008, 68:1022-1029.
    • (2008) Cancer Res. , vol.68 , pp. 1022-1029
    • Bocchetta, M.1    Eliasz, S.2    De Marco, M.A.3    Rudzinski, J.4    Zhang, L.5    Carbone, M.6
  • 57
    • 0037171944 scopus 로고    scopus 로고
    • Enhanced expression of vascular endothelial growth factor (VEGF) plays a critical role in the tumor progression potential induced by simian virus 40 large T antigen
    • Catalano A., Romano M., Martinotti S., Procopio A. Enhanced expression of vascular endothelial growth factor (VEGF) plays a critical role in the tumor progression potential induced by simian virus 40 large T antigen. Oncogene 2002, 25:2896-2900.
    • (2002) Oncogene , vol.25 , pp. 2896-2900
    • Catalano, A.1    Romano, M.2    Martinotti, S.3    Procopio, A.4
  • 59
    • 34248562292 scopus 로고    scopus 로고
    • SV40 oncoproteins enhance asbestos-induced DNA double-strand breaks and abrogate senescence in murine mesothelial cells
    • Pietruska J.R., Kane A.B. SV40 oncoproteins enhance asbestos-induced DNA double-strand breaks and abrogate senescence in murine mesothelial cells. Cancer Res. 2007, 67:3637-3645.
    • (2007) Cancer Res. , vol.67 , pp. 3637-3645
    • Pietruska, J.R.1    Kane, A.B.2
  • 60
    • 63949087814 scopus 로고    scopus 로고
    • Occupational, domestic and environmental mesothelioma risks in the British population: a case-control study
    • Rake C., Gilham C., Hatch J., Darnton A., Hodgson J., Peto J. Occupational, domestic and environmental mesothelioma risks in the British population: a case-control study. Br. J. Cancer 2009, 100:1175-1183.
    • (2009) Br. J. Cancer , vol.100 , pp. 1175-1183
    • Rake, C.1    Gilham, C.2    Hatch, J.3    Darnton, A.4    Hodgson, J.5    Peto, J.6
  • 61
    • 84863068162 scopus 로고
    • Relative mesothelioma induction in rats by mineral fibers: comparison with residual pulmonary mineral fiber number and epidemiology
    • Coffin D.L., Cook P.M., Creason J.P. Relative mesothelioma induction in rats by mineral fibers: comparison with residual pulmonary mineral fiber number and epidemiology. Inhal. Toxicol. 1992, 4:273-300.
    • (1992) Inhal. Toxicol. , vol.4 , pp. 273-300
    • Coffin, D.L.1    Cook, P.M.2    Creason, J.P.3
  • 63
    • 0023088676 scopus 로고
    • Epidemiological and environmental evidence of the health effects of exposure to erionite fibres: a four-year study in the Cappadocian region of Turkey
    • Baris I., Simonato L., Artvinli M., Pooley F., Saracci R., Skidmore J., Wagner C. Epidemiological and environmental evidence of the health effects of exposure to erionite fibres: a four-year study in the Cappadocian region of Turkey. Int. J. Cancer 1987, 39:10-17.
    • (1987) Int. J. Cancer , vol.39 , pp. 10-17
    • Baris, I.1    Simonato, L.2    Artvinli, M.3    Pooley, F.4    Saracci, R.5    Skidmore, J.6    Wagner, C.7
  • 66
    • 67149134686 scopus 로고    scopus 로고
    • North American erionite-associated mesothelioma with pleural plaques and pulmonary fibrosis: a case report
    • Kliment C., Clemens K., Oury T. North American erionite-associated mesothelioma with pleural plaques and pulmonary fibrosis: a case report. Int. J. Clin. Exp. Pathol. 2009, 2:407-410.
    • (2009) Int. J. Clin. Exp. Pathol. , vol.2 , pp. 407-410
    • Kliment, C.1    Clemens, K.2    Oury, T.3
  • 69
    • 84863012595 scopus 로고    scopus 로고
    • Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma
    • Carbone M., Yang H. Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. Clin. Cancer Res. 2013, 18:598-604.
    • (2013) Clin. Cancer Res. , vol.18 , pp. 598-604
    • Carbone, M.1    Yang, H.2
  • 70
    • 21644469663 scopus 로고    scopus 로고
    • Interleukin-1beta and tumour necrosis factor-alpha promote the transformation of human immortalised mesothelial cells by erionite
    • Wang Y., Faux S., Hallden G., Kirn D., Houghton C., Lemoine N., Patrick G. Interleukin-1beta and tumour necrosis factor-alpha promote the transformation of human immortalised mesothelial cells by erionite. Int. J. Oncol. 2004, 25:173-180.
    • (2004) Int. J. Oncol. , vol.25 , pp. 173-180
    • Wang, Y.1    Faux, S.2    Hallden, G.3    Kirn, D.4    Houghton, C.5    Lemoine, N.6    Patrick, G.7
  • 72
    • 0032517341 scopus 로고    scopus 로고
    • The p16INK4a/CDKN2A tumor suppressor and its relatives
    • Ruas M., Peters G. The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochim. Biophys. Acta 1998, 1378:F115-F177.
    • (1998) Biochim. Biophys. Acta , vol.1378
    • Ruas, M.1    Peters, G.2
  • 73
    • 84861968669 scopus 로고    scopus 로고
    • TGF-beta-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex
    • Thillainadesan G., Chitilian J.M., Isovic M., Ablack J.N., Mymryk J.S., Tini M., Torchia J. TGF-beta-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex. Mol. Cell 2012, 46:636-649.
    • (2012) Mol. Cell , vol.46 , pp. 636-649
    • Thillainadesan, G.1    Chitilian, J.M.2    Isovic, M.3    Ablack, J.N.4    Mymryk, J.S.5    Tini, M.6    Torchia, J.7
  • 76
    • 0038507189 scopus 로고    scopus 로고
    • Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer
    • Chang L.L., Yeh W.T., Yang S.Y., Wu W.J., Huang C.H. Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer. J. Urol. 2003, 170:595-600.
    • (2003) J. Urol. , vol.170 , pp. 595-600
    • Chang, L.L.1    Yeh, W.T.2    Yang, S.Y.3    Wu, W.J.4    Huang, C.H.5
  • 77
    • 2442566420 scopus 로고    scopus 로고
    • P16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma
    • Brown V.L., Harwood C.A., Crook T., Cronin J.G., Kelsell D.P., Proby C.M. p16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma. J. Invest. Dermatol. 2004, 122:1284-1292.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 1284-1292
    • Brown, V.L.1    Harwood, C.A.2    Crook, T.3    Cronin, J.G.4    Kelsell, D.P.5    Proby, C.M.6
  • 78
    • 18744377513 scopus 로고    scopus 로고
    • P16INK4A and p14ARF expression pattern by immunohistochemistry in human papillomavirus-related cervical neoplasia
    • Wang J.L., Zheng B.Y., Li X.D., Nokelainen K., Angstrom T., Lindstrom M.S., Wallin K.L. p16INK4A and p14ARF expression pattern by immunohistochemistry in human papillomavirus-related cervical neoplasia. Mod. Pathol. 2005, 18:629-637.
    • (2005) Mod. Pathol. , vol.18 , pp. 629-637
    • Wang, J.L.1    Zheng, B.Y.2    Li, X.D.3    Nokelainen, K.4    Angstrom, T.5    Lindstrom, M.S.6    Wallin, K.L.7
  • 80
    • 0038515139 scopus 로고    scopus 로고
    • Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas
    • Illei P.B., Rusch V.W., Zakowski M.F., Ladanyi M. Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas. Clin. Cancer Res. 2003, 9:2108-2113.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2108-2113
    • Illei, P.B.1    Rusch, V.W.2    Zakowski, M.F.3    Ladanyi, M.4
  • 81
    • 47049096400 scopus 로고    scopus 로고
    • 9p21 Deletion in the diagnosis of malignant mesothelioma in serous effusions additional to immunocytochemistry, DNA-ICM, and AgNOR analysis
    • Onofre F.B., Onofre A.S., Pomjanski N., Buckstegge B., Grote H.J., Bocking A. 9p21 Deletion in the diagnosis of malignant mesothelioma in serous effusions additional to immunocytochemistry, DNA-ICM, and AgNOR analysis. Cancer 2008, 114:204-215.
    • (2008) Cancer , vol.114 , pp. 204-215
    • Onofre, F.B.1    Onofre, A.S.2    Pomjanski, N.3    Buckstegge, B.4    Grote, H.J.5    Bocking, A.6
  • 88
    • 62549148264 scopus 로고    scopus 로고
    • Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice
    • Altomare D.A., Menges C.W., Pei J., Zhang L., Skele-Stump K.L., Carbone M., Kane A.B., Testa J.R. Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:3420-3425.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 3420-3425
    • Altomare, D.A.1    Menges, C.W.2    Pei, J.3    Zhang, L.4    Skele-Stump, K.L.5    Carbone, M.6    Kane, A.B.7    Testa, J.R.8
  • 90
    • 0032543305 scopus 로고    scopus 로고
    • Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression
    • Frizelle S., Grim J., Zhou J., Gupta P., Curiel D., Geradts J., Kratzke R. Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression. Oncogene 1998, 16:3087-3095.
    • (1998) Oncogene , vol.16 , pp. 3087-3095
    • Frizelle, S.1    Grim, J.2    Zhou, J.3    Gupta, P.4    Curiel, D.5    Geradts, J.6    Kratzke, R.7
  • 91
    • 0033664624 scopus 로고    scopus 로고
    • Gene therapy of established mesothelioma xenografts with recombinant p16INK4a adenovirus
    • Frizelle S., Rubins J., Zhou J., Curiel D., Kratzke R. Gene therapy of established mesothelioma xenografts with recombinant p16INK4a adenovirus. Cancer Gene Ther. 2000, 7:1421-1425.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1421-1425
    • Frizelle, S.1    Rubins, J.2    Zhou, J.3    Curiel, D.4    Kratzke, R.5
  • 92
    • 0344405743 scopus 로고    scopus 로고
    • A comparison analysis of anti-tumor efficacy of adenoviral gene replacement therapy (p14ARF and p16INK4A) in human mesothelioma cells
    • Yang C., You L., Lin Y., Lin C., McCormick F., Jablons D. A comparison analysis of anti-tumor efficacy of adenoviral gene replacement therapy (p14ARF and p16INK4A) in human mesothelioma cells. Anticancer Res. 2003, 23:33-38.
    • (2003) Anticancer Res. , vol.23 , pp. 33-38
    • Yang, C.1    You, L.2    Lin, Y.3    Lin, C.4    McCormick, F.5    Jablons, D.6
  • 93
    • 84874625850 scopus 로고    scopus 로고
    • A potential therapeutic strategy for malignant mesothelioma with gene medicine
    • Tada Y., Shimada H., Hiroshima K., Tagawa M. A potential therapeutic strategy for malignant mesothelioma with gene medicine. Biomed. Res. Int. 2013, 2013:8.
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 8
    • Tada, Y.1    Shimada, H.2    Hiroshima, K.3    Tagawa, M.4
  • 94
    • 70349706038 scopus 로고    scopus 로고
    • Neurofibromatosis 2 [bilateral acoustic neurofibromatosis, central neurofibromatosis, NF2, neurofibromatosis type II]
    • Evans D.G.R. Neurofibromatosis 2 [bilateral acoustic neurofibromatosis, central neurofibromatosis, NF2, neurofibromatosis type II]. Genet. Med. 2009, 11:599.
    • (2009) Genet. Med. , vol.11 , pp. 599
    • Evans, D.G.R.1
  • 95
    • 0028907620 scopus 로고
    • Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer
    • Sekido Y., Pass H.I., Bader S., Mew D.J.Y., Christman M.F., Gazdar A.F., Minna J.D. Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res. 1995, 55:1227-1231.
    • (1995) Cancer Res. , vol.55 , pp. 1227-1231
    • Sekido, Y.1    Pass, H.I.2    Bader, S.3    Mew, D.J.Y.4    Christman, M.F.5    Gazdar, A.F.6    Minna, J.D.7
  • 99
  • 101
    • 0032747316 scopus 로고    scopus 로고
    • Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer
    • Ikeda K., Saeki Y., Gonzalez-Agosti C., Ramesh V., Chiocca E.A. Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer. J. Neurosurg. 1999, 91:85-92.
    • (1999) J. Neurosurg. , vol.91 , pp. 85-92
    • Ikeda, K.1    Saeki, Y.2    Gonzalez-Agosti, C.3    Ramesh, V.4    Chiocca, E.A.5
  • 102
    • 0036154164 scopus 로고    scopus 로고
    • Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis
    • Schulze K.M.M., Hanemann C.O., Müller H.W., Hanenberg H. Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis. Hum. Mol. Genet. 2002, 11:69-76.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 69-76
    • Schulze, K.M.M.1    Hanemann, C.O.2    Müller, H.W.3    Hanenberg, H.4
  • 103
    • 3042626692 scopus 로고    scopus 로고
    • Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation
    • Fraenzer J., Pan H., Minimo L.J., Smith G., Knauer D., Hung G. Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation. Int. J. Oncol. 2003, 2003:1493-1500.
    • (2003) Int. J. Oncol. , vol.2003 , pp. 1493-1500
    • Fraenzer, J.1    Pan, H.2    Minimo, L.J.3    Smith, G.4    Knauer, D.5    Hung, G.6
  • 104
    • 77956296330 scopus 로고    scopus 로고
    • Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma
    • Morales F.C., Molina J.R., Hayashi Y., Georgescu M.-M. Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma. Neuro-Oncology 2010, 12:528-539.
    • (2010) Neuro-Oncology , vol.12 , pp. 528-539
    • Morales, F.C.1    Molina, J.R.2    Hayashi, Y.3    Georgescu, M.-M.4
  • 105
    • 33749188461 scopus 로고    scopus 로고
    • Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK
    • Poulikakos P., Xiao G., Gallagher R., Jablonski S., Jhanwar S., Testa J. Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK. Oncogene 2006, 25:5960-5980.
    • (2006) Oncogene , vol.25 , pp. 5960-5980
    • Poulikakos, P.1    Xiao, G.2    Gallagher, R.3    Jablonski, S.4    Jhanwar, S.5    Testa, J.6
  • 106
    • 14844355090 scopus 로고    scopus 로고
    • The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression
    • Xiao G.H., Gallagher R., Shetler J., Skele K., Altomare D.A., Pestell R.G., Jhanwar S., Testa J.R. The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression. Mol. Cell. Biol. 2005, 25:2384-2394.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2384-2394
    • Xiao, G.H.1    Gallagher, R.2    Shetler, J.3    Skele, K.4    Altomare, D.A.5    Pestell, R.G.6    Jhanwar, S.7    Testa, J.R.8
  • 107
    • 0035835437 scopus 로고    scopus 로고
    • Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey
    • Roushdy-Hammady I., Siegel J., Emri S., Testa J.R., Carbone M. Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey. Lancet 2001, 357:444-445.
    • (2001) Lancet , vol.357 , pp. 444-445
    • Roushdy-Hammady, I.1    Siegel, J.2    Emri, S.3    Testa, J.R.4    Carbone, M.5
  • 108
    • 33744913033 scopus 로고    scopus 로고
    • Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey
    • Dogan A.U., Baris Y.I., Dogan M., Emri S., Steele I., Elmishad A.G., Carbone M. Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey. Cancer Res. 2006, 66:5063-5068.
    • (2006) Cancer Res. , vol.66 , pp. 5063-5068
    • Dogan, A.U.1    Baris, Y.I.2    Dogan, M.3    Emri, S.4    Steele, I.5    Elmishad, A.G.6    Carbone, M.7
  • 109
    • 77952136510 scopus 로고    scopus 로고
    • Endemic malignant mesothelioma: exposure to erionite is more important than genetic factors
    • Metintas M., Hillerdal G., Metintas S., Dumortier P. Endemic malignant mesothelioma: exposure to erionite is more important than genetic factors. Arch. Environ. Occup. Health 2010, 65:86-93.
    • (2010) Arch. Environ. Occup. Health , vol.65 , pp. 86-93
    • Metintas, M.1    Hillerdal, G.2    Metintas, S.3    Dumortier, P.4
  • 114
    • 84886466708 scopus 로고    scopus 로고
    • Clinical characteristics of patients with malignant pleural mesothelioma harboring somatic BAP1 mutations
    • Zauderer M., Bott M., McMillan R., Sima C., Rusch V., Krug L., Ladanyi M. Clinical characteristics of patients with malignant pleural mesothelioma harboring somatic BAP1 mutations. J. Thorac. Oncol. 2013, 8:1430-1433.
    • (2013) J. Thorac. Oncol. , vol.8 , pp. 1430-1433
    • Zauderer, M.1    Bott, M.2    McMillan, R.3    Sima, C.4    Rusch, V.5    Krug, L.6    Ladanyi, M.7
  • 116
    • 84873827063 scopus 로고    scopus 로고
    • Tumours associated with BAP1 mutations
    • Murali R., Wiesner T., Scolyer R. Tumours associated with BAP1 mutations. Pathology 2013, 45:116-126.
    • (2013) Pathology , vol.45 , pp. 116-126
    • Murali, R.1    Wiesner, T.2    Scolyer, R.3
  • 118
    • 0028902594 scopus 로고
    • The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
    • Justice R.W., Zilian O., Woods D.F., Noll M., Bryant P.J. The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev. 1995, 9:534-546.
    • (1995) Genes Dev. , vol.9 , pp. 534-546
    • Justice, R.W.1    Zilian, O.2    Woods, D.F.3    Noll, M.4    Bryant, P.J.5
  • 120
    • 84984578438 scopus 로고    scopus 로고
    • Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11
    • Chen C.F., Yeh S.H., Chen D.S., Chen P.J., Jou Y.S. Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11. Genes Chromosom. Cancer 2005, 44:320-328.
    • (2005) Genes Chromosom. Cancer , vol.44 , pp. 320-328
    • Chen, C.F.1    Yeh, S.H.2    Chen, D.S.3    Chen, P.J.4    Jou, Y.S.5
  • 121
    • 33749334018 scopus 로고    scopus 로고
    • A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization
    • Aylon Y., Michael D., Shmueli A., Yabuta N., Nojima H., Oren M. A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. Genes Dev. 2006, 20:2687-2700.
    • (2006) Genes Dev. , vol.20 , pp. 2687-2700
    • Aylon, Y.1    Michael, D.2    Shmueli, A.3    Yabuta, N.4    Nojima, H.5    Oren, M.6
  • 122
    • 78049435859 scopus 로고    scopus 로고
    • The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1
    • Aylon Y., Ofir-Rosenfeld Y., Yabuta N., Lapi E., Nojima H., Lu X., Oren M. The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1. Genes Dev. 2010, 24:2420-2429.
    • (2010) Genes Dev. , vol.24 , pp. 2420-2429
    • Aylon, Y.1    Ofir-Rosenfeld, Y.2    Yabuta, N.3    Lapi, E.4    Nojima, H.5    Lu, X.6    Oren, M.7
  • 123
    • 77958494807 scopus 로고    scopus 로고
    • LATS tumor suppressor: a new governor of cellular homeostasis
    • Visser S., Yang X. LATS tumor suppressor: a new governor of cellular homeostasis. Cell Cycle 2010, 9:3922-3933.
    • (2010) Cell Cycle , vol.9 , pp. 3922-3933
    • Visser, S.1    Yang, X.2
  • 134
    • 0037162714 scopus 로고    scopus 로고
    • Salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
    • Tapon N., Harvey K.F., Bell D.W., Wahrer D.C.R., Schiripo T.A., Haber D.A., Hariharan I.K. salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 2002, 110:467-478.
    • (2002) Cell , vol.110 , pp. 467-478
    • Tapon, N.1    Harvey, K.F.2    Bell, D.W.3    Wahrer, D.C.R.4    Schiripo, T.A.5    Haber, D.A.6    Hariharan, I.K.7
  • 138
    • 84890547769 scopus 로고    scopus 로고
    • Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro
    • You M., Varona-Santos J., Singh S., Robbins D.J., Savaraj N., Nguyen D.M. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. J. Thorac. Cardiovasc. Surg. 2013, 147(1):508-516.
    • (2013) J. Thorac. Cardiovasc. Surg. , vol.147 , Issue.1 , pp. 508-516
    • You, M.1    Varona-Santos, J.2    Singh, S.3    Robbins, D.J.4    Savaraj, N.5    Nguyen, D.M.6
  • 140
    • 84881261418 scopus 로고    scopus 로고
    • Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines
    • Klorin G., Rozenblum E., Glebov O., Walker R.L., Park Y., Meltzer P.S., Kirsch I.R., Kaye F.J., Roschke A.V. Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines. Cancer Genet. 2013, 206:191-205.
    • (2013) Cancer Genet. , vol.206 , pp. 191-205
    • Klorin, G.1    Rozenblum, E.2    Glebov, O.3    Walker, R.L.4    Park, Y.5    Meltzer, P.S.6    Kirsch, I.R.7    Kaye, F.J.8    Roschke, A.V.9
  • 141
    • 84869125804 scopus 로고    scopus 로고
    • Circadian rhythm disruption in cancer biology
    • Savvidis C., Koutsilieris M. Circadian rhythm disruption in cancer biology. Mol. Med. 2012, 18:1249-1260.
    • (2012) Mol. Med. , vol.18 , pp. 1249-1260
    • Savvidis, C.1    Koutsilieris, M.2
  • 142
    • 14644415433 scopus 로고    scopus 로고
    • Circadian disruption and breast cancer: from melatonin to clock genes
    • Stevens R.G. Circadian disruption and breast cancer: from melatonin to clock genes. Epidemiology 2005, 16:254-258.
    • (2005) Epidemiology , vol.16 , pp. 254-258
    • Stevens, R.G.1
  • 144
  • 146
    • 79955459524 scopus 로고    scopus 로고
    • Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy
    • Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B., Rusch V., Ladanyi M. Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy. J. Thorac. Oncol. 2011, 6:864-874.
    • (2011) J. Thorac. Oncol. , vol.6 , pp. 864-874
    • Brevet, M.1    Shimizu, S.2    Bott, M.J.3    Shukla, N.4    Zhou, Q.5    Olshen, A.B.6    Rusch, V.7    Ladanyi, M.8
  • 147
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Lemmon M.A., Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010, 141:1117-1134.
    • (2010) Cell , vol.141 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 148
    • 80052367585 scopus 로고    scopus 로고
    • Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand?
    • Agarwal V., Lind M.J., Cawkwell L. Targeted epidermal growth factor receptor therapy in malignant pleural mesothelioma: where do we stand?. Cancer Treat. Rev. 2011, 37:533-542.
    • (2011) Cancer Treat. Rev. , vol.37 , pp. 533-542
    • Agarwal, V.1    Lind, M.J.2    Cawkwell, L.3
  • 153
    • 0031879683 scopus 로고    scopus 로고
    • Independent expression of serum vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in patients with carcinoma and sarcoma
    • Linder C., Linder S., Munck-Wikland E., Strander H. Independent expression of serum vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in patients with carcinoma and sarcoma. Anticancer Res. 1998, 18:2063-2068.
    • (1998) Anticancer Res. , vol.18 , pp. 2063-2068
    • Linder, C.1    Linder, S.2    Munck-Wikland, E.3    Strander, H.4
  • 154
    • 0032818742 scopus 로고    scopus 로고
    • Angiogenic cytokines in mesothelioma: a study of VEGF, FGF-1 and -2, and TGF beta expression
    • Kumar-Singh S., Weyler J., Martin M.J., Vermeulen P.B., Van Marck E. Angiogenic cytokines in mesothelioma: a study of VEGF, FGF-1 and -2, and TGF beta expression. J. Pathol. 1999, 189:72-78.
    • (1999) J. Pathol. , vol.189 , pp. 72-78
    • Kumar-Singh, S.1    Weyler, J.2    Martin, M.J.3    Vermeulen, P.B.4    Van Marck, E.5
  • 155
    • 28144446498 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial growth factor, tumor necrosis, and mitotic activity index in malignant pleural mesothelioma*
    • Demirag F., UÌ̂nsal E., Yilmaz A., Çağlar A. Prognostic significance of vascular endothelial growth factor, tumor necrosis, and mitotic activity index in malignant pleural mesothelioma*. Chest J. 2005, 128:3382-3387.
    • (2005) Chest J. , vol.128 , pp. 3382-3387
    • Demirag, F.1    Uì̂nsal, E.2    Yilmaz, A.3    Cì§ağlar, A.4
  • 157
    • 84859889071 scopus 로고    scopus 로고
    • Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma
    • Favoni R.E., Daga A., Malatesta P., Florio T. Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma. Br. J. Pharmacol. 2012, 166:532-553.
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 532-553
    • Favoni, R.E.1    Daga, A.2    Malatesta, P.3    Florio, T.4
  • 159
    • 33745684876 scopus 로고    scopus 로고
    • Molecular pathways in malignant pleural mesothelioma
    • Whitson B.A., Kratzke R.A. Molecular pathways in malignant pleural mesothelioma. Cancer Lett. 2006, 239:183-189.
    • (2006) Cancer Lett. , vol.239 , pp. 183-189
    • Whitson, B.A.1    Kratzke, R.A.2
  • 161
    • 5644280150 scopus 로고    scopus 로고
    • Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes
    • Hoang C.D., Zhang X., Scott P.D., Guillaume T.J., Maddaus M.A., Yee D., Kratzke R.A. Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes. Cancer Res. 2004, 64:7479-7485.
    • (2004) Cancer Res. , vol.64 , pp. 7479-7485
    • Hoang, C.D.1    Zhang, X.2    Scott, P.D.3    Guillaume, T.J.4    Maddaus, M.A.5    Yee, D.6    Kratzke, R.A.7
  • 162
    • 84865544289 scopus 로고    scopus 로고
    • Efficacy of anti-insulin-like growth factor I receptor monoclonal antibody cixutumumab in mesothelioma is highly correlated with insulin growth factor-I receptor sites/cell
    • Kalra N., Zhang J., Yu Y., Ho M., Merino M., Cao L., Hassan R. Efficacy of anti-insulin-like growth factor I receptor monoclonal antibody cixutumumab in mesothelioma is highly correlated with insulin growth factor-I receptor sites/cell. Int. J. Cancer 2012, 131:2143-2152.
    • (2012) Int. J. Cancer , vol.131 , pp. 2143-2152
    • Kalra, N.1    Zhang, J.2    Yu, Y.3    Ho, M.4    Merino, M.5    Cao, L.6    Hassan, R.7
  • 165
    • 0034039427 scopus 로고    scopus 로고
    • Immunoreactivity for cadherins, HGF/SF, met, and erbB-2 in pleural malignant mesotheliomas
    • Thirkettle I., Harvey P., Hasleton P.S., Ball R.Y., Warn R.M. Immunoreactivity for cadherins, HGF/SF, met, and erbB-2 in pleural malignant mesotheliomas. Histopathology 2000, 36:522-528.
    • (2000) Histopathology , vol.36 , pp. 522-528
    • Thirkettle, I.1    Harvey, P.2    Hasleton, P.S.3    Ball, R.Y.4    Warn, R.M.5
  • 170
    • 80052204526 scopus 로고    scopus 로고
    • Evolutionary expansion of the Ras switch regulatory module in eukaryotes
    • Díez D., Sánchez-Jiménez F., Ranea J. Evolutionary expansion of the Ras switch regulatory module in eukaryotes. Nucleic Acids Res. 2011, 39(13):5526-5537.
    • (2011) Nucleic Acids Res. , vol.39 , Issue.13 , pp. 5526-5537
    • Díez, D.1    Sánchez-Jiménez, F.2    Ranea, J.3
  • 172
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer?
    • Mebratu Y., Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer?. Cell Cycle 2009, 8:1168-1175.
    • (2009) Cell Cycle , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 174
    • 33746278685 scopus 로고    scopus 로고
    • Phosphorylated extracellular signal-regulated kinases are significantly increased in malignant mesothelioma
    • Melo M.d., Gerbase M.W., Curran J., Pache J.C. Phosphorylated extracellular signal-regulated kinases are significantly increased in malignant mesothelioma. J. Histochem. Cytochem. 2006, 54:855-861.
    • (2006) J. Histochem. Cytochem. , vol.54 , pp. 855-861
    • Melo, M.1    Gerbase, M.W.2    Curran, J.3    Pache, J.C.4
  • 175
    • 18844401069 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells
    • Vintman L., Nielsen S., Berner A., Reich R., Davidson B. Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells. Cancer 2005, 103:2427-2433.
    • (2005) Cancer , vol.103 , pp. 2427-2433
    • Vintman, L.1    Nielsen, S.2    Berner, A.3    Reich, R.4    Davidson, B.5
  • 176
    • 0030447748 scopus 로고    scopus 로고
    • Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor
    • Zanella C.L., Posada J., Tritton T.R., Mossman B.T. Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor. Cancer Res. 1996, 56:5334-5338.
    • (1996) Cancer Res. , vol.56 , pp. 5334-5338
    • Zanella, C.L.1    Posada, J.2    Tritton, T.R.3    Mossman, B.T.4
  • 177
    • 0037370828 scopus 로고    scopus 로고
    • Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis
    • Cummins A.B., Palmer C., Mossman B.T., Taatjes D.J. Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis. Am. J. Pathol. 2003, 162:713-720.
    • (2003) Am. J. Pathol. , vol.162 , pp. 713-720
    • Cummins, A.B.1    Palmer, C.2    Mossman, B.T.3    Taatjes, D.J.4
  • 179
    • 0035190026 scopus 로고    scopus 로고
    • Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer
    • Katso R., Okkenhaug K., Ahmadi K., White S., Timms J., Waterfield M.D. Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 2001, 17:615-675.
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 615-675
    • Katso, R.1    Okkenhaug, K.2    Ahmadi, K.3    White, S.4    Timms, J.5    Waterfield, M.D.6
  • 180
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • Engelman J.A., Luo J., Cantley L.C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 2006, 7:606-619.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 181
    • 66149141021 scopus 로고    scopus 로고
    • PTEN and the PI3-kinase pathway in cancer
    • Chalhoub N., Baker S.J. PTEN and the PI3-kinase pathway in cancer. Annu. Rev. Pathol. 2009, 4:127-150.
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 127-150
    • Chalhoub, N.1    Baker, S.J.2
  • 183
    • 51849111556 scopus 로고    scopus 로고
    • PI3K pathway alterations in cancer: variations on a theme
    • Yuan T.L., Cantley L.C. PI3K pathway alterations in cancer: variations on a theme. Oncogene 2008, 27:5497-5510.
    • (2008) Oncogene , vol.27 , pp. 5497-5510
    • Yuan, T.L.1    Cantley, L.C.2
  • 184
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning B.D., Cantley L.C. AKT/PKB signaling: navigating downstream. Cell 2007, 129:1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 186
    • 77957288035 scopus 로고    scopus 로고
    • Expanding therapeutic targets in bladder cancer: the PI3K/Akt/mTOR pathway
    • Ching C.B., Hansel D.E. Expanding therapeutic targets in bladder cancer: the PI3K/Akt/mTOR pathway. Lab. Invest. 2010, 90:1406-1414.
    • (2010) Lab. Invest. , vol.90 , pp. 1406-1414
    • Ching, C.B.1    Hansel, D.E.2
  • 187
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5' cap-binding protein eIF4E and control of cell growth
    • Sonenberg N., Gingras A.C. The mRNA 5' cap-binding protein eIF4E and control of cell growth. Curr. Opin. Cell Biol. 1998, 10:268-275.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 188
    • 0030740005 scopus 로고    scopus 로고
    • The modular phosphorylation and activation of p70s6k
    • Pullen N., Thomas G. The modular phosphorylation and activation of p70s6k. FEBS Lett. 1997, 410:78-82.
    • (1997) FEBS Lett. , vol.410 , pp. 78-82
    • Pullen, N.1    Thomas, G.2
  • 189
    • 20044374361 scopus 로고    scopus 로고
    • Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase
    • Ramos-Nino M.E., Vianale G., Sabo-Attwood T., Mutti L., Porta C., Heintz N., Mossman B.T. Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase. Mol. Cancer Ther. 2005, 4:835-842.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 835-842
    • Ramos-Nino, M.E.1    Vianale, G.2    Sabo-Attwood, T.3    Mutti, L.4    Porta, C.5    Heintz, N.6    Mossman, B.T.7
  • 191
    • 35348820823 scopus 로고    scopus 로고
    • Targeting the mTOR signaling network in cancer
    • Chiang G.G., Abraham R.T. Targeting the mTOR signaling network in cancer. Trends Mol. Med. 2007, 13:433-442.
    • (2007) Trends Mol. Med. , vol.13 , pp. 433-442
    • Chiang, G.G.1    Abraham, R.T.2
  • 192
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: one gene, many syndromes
    • Eng C. PTEN: one gene, many syndromes. Hum. Mutat. 2003, 22:183-198.
    • (2003) Hum. Mutat. , vol.22 , pp. 183-198
    • Eng, C.1
  • 193
    • 0035863411 scopus 로고    scopus 로고
    • AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells
    • Tanno S., Tanno S., Mitsuuchi Y., Altomare D.A., Xiao G.H., Testa J.R. AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res. 2001, 61:589-593.
    • (2001) Cancer Res. , vol.61 , pp. 589-593
    • Tanno, S.1    Tanno, S.2    Mitsuuchi, Y.3    Altomare, D.A.4    Xiao, G.H.5    Testa, J.R.6
  • 195
    • 0032527913 scopus 로고    scopus 로고
    • AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells
    • Liu A.-x., Testa J.R., Hamilton T.C., Jove R., Nicosia S.V., Cheng J.Q. AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells. Cancer Res. 1998, 58:2973-2977.
    • (1998) Cancer Res. , vol.58 , pp. 2973-2977
    • Liu, A.-X.1    Testa, J.R.2    Hamilton, T.C.3    Jove, R.4    Nicosia, S.V.5    Cheng, J.Q.6
  • 197
    • 0242499482 scopus 로고    scopus 로고
    • Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3'-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas
    • Knobbe C.B., Reifenberger G. Genetic alterations and aberrant expression of genes related to the phosphatidyl-inositol-3'-kinase/protein kinase B (Akt) signal transduction pathway in glioblastomas. Brain Pathol. 2003, 13:507-518.
    • (2003) Brain Pathol. , vol.13 , pp. 507-518
    • Knobbe, C.B.1    Reifenberger, G.2
  • 198
  • 199
    • 33745888913 scopus 로고    scopus 로고
    • PTEN function in normal and neoplastic growth
    • Chow L.M., Baker S.J. PTEN function in normal and neoplastic growth. Cancer Lett. 2006, 241:184-196.
    • (2006) Cancer Lett. , vol.241 , pp. 184-196
    • Chow, L.M.1    Baker, S.J.2
  • 201
    • 0036221096 scopus 로고    scopus 로고
    • Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation
    • Mohiuddin I., Cao X., Ozvaran M.K., Zumstein L., Chada S., Smythe W.R. Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation. Ann. Surg. Oncol. 2002, 9:310-316.
    • (2002) Ann. Surg. Oncol. , vol.9 , pp. 310-316
    • Mohiuddin, I.1    Cao, X.2    Ozvaran, M.K.3    Zumstein, L.4    Chada, S.5    Smythe, W.R.6
  • 203
    • 77951884299 scopus 로고    scopus 로고
    • Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS
    • Zhao L., Vogt P.K. Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS. Cell Cycle 2010, 9:596-600.
    • (2010) Cell Cycle , vol.9 , pp. 596-600
    • Zhao, L.1    Vogt, P.K.2
  • 205
    • 78650997009 scopus 로고    scopus 로고
    • Activation of the phosphoinositide-3-kinase and mammalian target of rapamycin signaling pathways are associated with shortened survival in patients with malignant peritoneal mesothelioma
    • Varghese S., Chen Z., Bartlett D.L., Pingpank J.F., Libutti S.K., Steinberg S.M., Wunderlich J., Alexander H.R. Activation of the phosphoinositide-3-kinase and mammalian target of rapamycin signaling pathways are associated with shortened survival in patients with malignant peritoneal mesothelioma. Cancer 2011, 117:361-371.
    • (2011) Cancer , vol.117 , pp. 361-371
    • Varghese, S.1    Chen, Z.2    Bartlett, D.L.3    Pingpank, J.F.4    Libutti, S.K.5    Steinberg, S.M.6    Wunderlich, J.7    Alexander, H.R.8
  • 206
    • 2542443539 scopus 로고    scopus 로고
    • Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development
    • Fennell D.A., Rudd R.M. Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development. Lancet Oncol. 2004, 5:354-362.
    • (2004) Lancet Oncol. , vol.5 , pp. 354-362
    • Fennell, D.A.1    Rudd, R.M.2
  • 207
    • 33846230965 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model
    • Bedogni B., Welford S.M., Kwan A.C., Ranger-Moore J., Saboda K., Powell M.B. Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model. Mol. Cancer Ther. 2006, 5:3071-3077.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 3071-3077
    • Bedogni, B.1    Welford, S.M.2    Kwan, A.C.3    Ranger-Moore, J.4    Saboda, K.5    Powell, M.B.6
  • 208
    • 33645805911 scopus 로고    scopus 로고
    • Suppression of Pro-metastasis phenotypes expression in malignant pleural mesothelioma by the PI3K inhibitor LY294002 or the MEK inhibitor UO126
    • Cole G.W., Alleva A.M., Zuo J.T., Sehgal S.S., Yeow W.-S., Schrump D.S., Nguyen D.M. Suppression of Pro-metastasis phenotypes expression in malignant pleural mesothelioma by the PI3K inhibitor LY294002 or the MEK inhibitor UO126. Anticancer Res. 2006, 26:809-821.
    • (2006) Anticancer Res. , vol.26 , pp. 809-821
    • Cole, G.W.1    Alleva, A.M.2    Zuo, J.T.3    Sehgal, S.S.4    Yeow, W.-S.5    Schrump, D.S.6    Nguyen, D.M.7
  • 209
    • 45149094559 scopus 로고    scopus 로고
    • Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids
    • Barbone D., Yang T.M., Morgan J.R., Gaudino G., Broaddus V.C. Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids. J. Biol. Chem. 2008, 283:13021-13030.
    • (2008) J. Biol. Chem. , vol.283 , pp. 13021-13030
    • Barbone, D.1    Yang, T.M.2    Morgan, J.R.3    Gaudino, G.4    Broaddus, V.C.5
  • 210
    • 34247163550 scopus 로고    scopus 로고
    • Chemically targeting the PI3K family
    • Knight Z.A., Shokat K.M. Chemically targeting the PI3K family. Biochem. Soc. Trans. 2007, 35:245-249.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 245-249
    • Knight, Z.A.1    Shokat, K.M.2
  • 213
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 214
    • 6044233149 scopus 로고    scopus 로고
    • Mesothelial cell proliferation and apoptosis
    • Leard L.E., Broaddus V.C. Mesothelial cell proliferation and apoptosis. Respirology 2004, 9:292-299.
    • (2004) Respirology , vol.9 , pp. 292-299
    • Leard, L.E.1    Broaddus, V.C.2
  • 215
    • 0031817980 scopus 로고    scopus 로고
    • Resistance of pleural mesothelioma cell lines to apoptosis: relation to expression of Bcl-2 and Bax
    • Narasimhan S.R., Yang L., Gerwin B.I., Broaddus V.C. Resistance of pleural mesothelioma cell lines to apoptosis: relation to expression of Bcl-2 and Bax. Am. J. Physiol. 1998, 275:L165-L171.
    • (1998) Am. J. Physiol. , vol.275
    • Narasimhan, S.R.1    Yang, L.2    Gerwin, B.I.3    Broaddus, V.C.4
  • 216
    • 0034602188 scopus 로고    scopus 로고
    • Role of BAX in the apoptotic response to anticancer agents
    • Zhang L., Yu J., Park B.H., Kinzler K.W., Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science 2000, 290:989-992.
    • (2000) Science , vol.290 , pp. 989-992
    • Zhang, L.1    Yu, J.2    Park, B.H.3    Kinzler, K.W.4    Vogelstein, B.5
  • 218
  • 219
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a strategy for cancer drug discovery
    • Fesik S.W. Promoting apoptosis as a strategy for cancer drug discovery. Nat. Rev. Cancer 2005, 5:876-885.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 220
    • 0035184066 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma
    • Cao X.X., Mohuiddin I., Ece F., McConkey D.J., Smythe W.R. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. Am. J. Respir. Cell Mol. Biol. 2001, 25:562-568.
    • (2001) Am. J. Respir. Cell Mol. Biol. , vol.25 , pp. 562-568
    • Cao, X.X.1    Mohuiddin, I.2    Ece, F.3    McConkey, D.J.4    Smythe, W.R.5
  • 221
    • 0036621573 scopus 로고    scopus 로고
    • Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product
    • Smythe W.R., Mohuiddin I., Ozveran M., Cao X.X. Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product. J. Thorac. Cardiovasc. Surg. 2002, 123:1191-1198.
    • (2002) J. Thorac. Cardiovasc. Surg. , vol.123 , pp. 1191-1198
    • Smythe, W.R.1    Mohuiddin, I.2    Ozveran, M.3    Cao, X.X.4
  • 222
    • 43949111975 scopus 로고    scopus 로고
    • Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts
    • Littlejohn J.E., Cao X., Miller S.D., Ozvaran M.K., Jupiter D., Zhang L., Rodarte C., Smythe W.R. Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. Int. J. Cancer 2008, 123:202-208.
    • (2008) Int. J. Cancer , vol.123 , pp. 202-208
    • Littlejohn, J.E.1    Cao, X.2    Miller, S.D.3    Ozvaran, M.K.4    Jupiter, D.5    Zhang, L.6    Rodarte, C.7    Smythe, W.R.8
  • 225
    • 69249211723 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells
    • Yuan B.Z., Chapman J.A., Reynolds S.H. Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells. Transl. Oncol. 2008, 1:129-140.
    • (2008) Transl. Oncol. , vol.1 , pp. 129-140
    • Yuan, B.Z.1    Chapman, J.A.2    Reynolds, S.H.3
  • 226
    • 84864063110 scopus 로고    scopus 로고
    • Merlin: the wizard requires protein stability to function as a tumor suppressor
    • Morrow K.A., Shevde L.A. Merlin: the wizard requires protein stability to function as a tumor suppressor. Biochim. Biophys. Acta, Rev. Cancer 2012, 1826:400-406.
    • (2012) Biochim. Biophys. Acta, Rev. Cancer , vol.1826 , pp. 400-406
    • Morrow, K.A.1    Shevde, L.A.2
  • 227
    • 0028229539 scopus 로고
    • ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons
    • Tsukita S., Oishi K., Sato N., Sagara J., Kawai A. ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J. Cell Biol. 1994, 126:391-401.
    • (1994) J. Cell Biol. , vol.126 , pp. 391-401
    • Tsukita, S.1    Oishi, K.2    Sato, N.3    Sagara, J.4    Kawai, A.5
  • 228
    • 78649631289 scopus 로고    scopus 로고
    • Merlin, a "Magic" linker between the extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival
    • Stamenkovic I., Yu Q. Merlin, a "Magic" linker between the extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival. Curr. Protein Pept. Sci. 2010, 11:471-484.
    • (2010) Curr. Protein Pept. Sci. , vol.11 , pp. 471-484
    • Stamenkovic, I.1    Yu, Q.2
  • 229
    • 11144229268 scopus 로고    scopus 로고
    • Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L
    • Rong R., Tang X., Gutmann D.H., Ye K. Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L. Proc. Natl. Acad. Sci. 2004, 101:18200-18205.
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 18200-18205
    • Rong, R.1    Tang, X.2    Gutmann, D.H.3    Ye, K.4
  • 230
  • 232
    • 63049127084 scopus 로고    scopus 로고
    • Functional inactivation of NF2/merlin in human mesothelioma
    • (Amsterdam, Netherlands)
    • Thurneysen C., Opitz I., Kurtz S., Weder W., Stahel R.A., Felley-Bosco E. Functional inactivation of NF2/merlin in human mesothelioma. Lung Cancer 2009, 64:140-147. (Amsterdam, Netherlands).
    • (2009) Lung Cancer , vol.64 , pp. 140-147
    • Thurneysen, C.1    Opitz, I.2    Kurtz, S.3    Weder, W.4    Stahel, R.A.5    Felley-Bosco, E.6
  • 234
    • 8444251784 scopus 로고    scopus 로고
    • The WNT signaling pathway in development and disease
    • Logan C.Y., Nusse R. The WNT signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 2004, 20:781-810.
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 235
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A., Birchmeier W. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 2008, 8:387-398.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 236
    • 67650230896 scopus 로고    scopus 로고
    • 2-catenin signaling: components, mechanisms, and diseases
    • 2-catenin signaling: components, mechanisms, and diseases. Dev. Cell 2009, 17:9-26.
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 237
  • 240
    • 0242643649 scopus 로고    scopus 로고
    • Cadherins, catenins and APC in pleural malignant mesothelioma
    • Abutaily A.S., Collins J.E., Roche W.R. Cadherins, catenins and APC in pleural malignant mesothelioma. J. Pathol. 2003, 201:355-362.
    • (2003) J. Pathol. , vol.201 , pp. 355-362
    • Abutaily, A.S.1    Collins, J.E.2    Roche, W.R.3
  • 241
    • 84856698418 scopus 로고    scopus 로고
    • Beta-catenin expression in benign and malignant pleural disorders
    • Anani W., Bruggeman R., Zander D.S. Beta-catenin expression in benign and malignant pleural disorders. Int. J. Clin. Exp. Pathol. 2011, 4:742-747.
    • (2011) Int. J. Clin. Exp. Pathol. , vol.4 , pp. 742-747
    • Anani, W.1    Bruggeman, R.2    Zander, D.S.3
  • 246
    • 27744567974 scopus 로고    scopus 로고
    • The expression pattern of β-catenin in mesothelial proliferative lesions and its diagnostic utilities
    • Dai Y., Bedrossian C.W.M., Michael C.W. The expression pattern of β-catenin in mesothelial proliferative lesions and its diagnostic utilities. Diagn. Cytopathol. 2005, 33:320-324.
    • (2005) Diagn. Cytopathol. , vol.33 , pp. 320-324
    • Dai, Y.1    Bedrossian, C.W.M.2    Michael, C.W.3
  • 247
    • 33846674993 scopus 로고    scopus 로고
    • Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32
    • Taniguchi T., Karnan S., Fukui T., Yokoyama T., Tagawa H., Yokoi K., Ueda Y., Mitsudomi T., Horio Y., Hida T., Yatabe Y., Seto M., Sekido Y. Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32. Cancer Sci. 2007, 98:438-446.
    • (2007) Cancer Sci. , vol.98 , pp. 438-446
    • Taniguchi, T.1    Karnan, S.2    Fukui, T.3    Yokoyama, T.4    Tagawa, H.5    Yokoi, K.6    Ueda, Y.7    Mitsudomi, T.8    Horio, Y.9    Hida, T.10    Yatabe, Y.11    Seto, M.12    Sekido, Y.13
  • 250
    • 84880265119 scopus 로고    scopus 로고
    • Morphology of 9p21 homozygous deletion-positive pleural mesothelioma cells analyzed using fluorescence in situ hybridization and virtual microscope system in effusion cytology
    • Matsumoto S., Nabeshima K., Kamei T., Hiroshima K., Kawahara K., Hata S., Marukawa K., Matsuno Y., Taguchi K., Tsujimura T. Morphology of 9p21 homozygous deletion-positive pleural mesothelioma cells analyzed using fluorescence in situ hybridization and virtual microscope system in effusion cytology. Cancer Cytopathol. 2013, 121:415-422.
    • (2013) Cancer Cytopathol. , vol.121 , pp. 415-422
    • Matsumoto, S.1    Nabeshima, K.2    Kamei, T.3    Hiroshima, K.4    Kawahara, K.5    Hata, S.6    Marukawa, K.7    Matsuno, Y.8    Taguchi, K.9    Tsujimura, T.10
  • 251
    • 0001387683 scopus 로고    scopus 로고
    • Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation
    • Cheng J.Q., Lee W.C., Klein M.A., Cheng G.Z., Jhanwar S.C., Testa J.R. Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation. Genes Chromosom. Cancer 1999, 24:238-242.
    • (1999) Genes Chromosom. Cancer , vol.24 , pp. 238-242
    • Cheng, J.Q.1    Lee, W.C.2    Klein, M.A.3    Cheng, G.Z.4    Jhanwar, S.C.5    Testa, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.