Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 52, 2004, Pages 18200-18205

  Rong, Rong ^a   Tang, Xiaoling ^a   Gutmann, David H ^b   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MERLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE ENHANCER L PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOTHESIS; NEURILEMOMA; NEUROFIBROMATOSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOVIRIDAE; ANIMALS; CELL LINE; CELL PROLIFERATION; COLORING AGENTS; GLUTATHIONE TRANSFERASE; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HUMANS; IMMUNOPRECIPITATION; LEUCINE; MICROSCOPY, FLUORESCENCE; MUTATION; NEURILEMMOMA; NEUROFIBROMATOSIS 2; NEUROFIBROMIN 2; POINT MUTATION; PROTEIN BINDING; RATS; RNA INTERFERENCE; SUBCELLULAR FRACTIONS; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

ANIMALIA; FALCO COLUMBARIUS;

EID: 11144229268     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0405971102     Document Type: Article

References (40)

1. Eldridge, R. (1981) Adv. Neurol. 29, 57-65.
2. Rouleau, G. A., Merel, P., Lutchman, M., Sanson, M., Zucman, J., Marincau, C., Hoang-Xuan, K., Demezuk, S., Desmaze, C., Plougastel, B., et al. (1993) Nature 363, 515-521.
3. Trofatter, J. A., MacCollin, M. M., Rutter, J. L., Murrell, J. R., Duyao, M. P., Parry, D. M., Eldridge, R., Kley, N., Menon, A. G., Pulaski, K., et al. (1993) Cell 72, 791-800.
4. Gutmann, D. H. (1997) Neurobiol. Dis. 3, 247-261.
5. Gonzalez-Agosti, C., Xu, L., Pinney, D., Beauchamp, R., Hobbs, W., Gusella, J. & Ramesh, V. (1996) Oncogene 13, 1239-1247.
6. Scherer, S. S. & Gutmann, D. H. (1996) J. Neurosci. Res. 46, 595-605.
7. Gutmann, D. H., Sherman, L., Seftor, L., Haipek, C., Hoang Lu, K. & Hendrix, M. (1999) Hum. Mol. Genet. 8, 267-275.
8. Sherman, L., Xu, H. M., Geist, R. T., Saporito-Irwin, S., Howells, N., Ponta, H., Herrlich, P. & Gutmann, D. H. (1997) Oncogene 15, 2505-2509.
9. Huynh, D. P. & Pulst, S. M. (1996) Oncogene 13, 73-84.
10. Gonzalez-Agosti, C., Wiederhold, T., Herndon, M. E., Gusella, J. & Ramesh, V. (1999) J. Biol. Chem. 274, 34438-34442.
11. Gutmann, D. H., Geist, R. T., Xu, H., Kim, J. S. & Saporito-Irwin, S. (1998) Hum. Mol. Genet. 7, 335-345.
12. Gutmann, D. H., Haipek, C. A. & Hoang Lu, K. (1999) J. Neurosci. Res. 58, 706-716.
13. Meng, J. J., Lowrie, D. J., Sun, H., Dorsey, E., Pelton, P. D., Bashour, A. M., Groden, J., Ratner, N. & Ip, W. (2000) J. Neurosci. Res. 62, 491-502.
14. Gutmann, D. H. (2001) Hum. Mol. Genet. 10, 747-755.
15. Ye, K., Hurt, K. J., Wu, F. Y., Fang, M., Luo, H. R., Hong, J. J., Blackshaw, S., Ferris, C. D. & Snyder, S. H. (2000) Cell 103, 919-930.
16. Ye, K., Aghdasi, B., Luo, H. R., Moriarity, J. L., Wu, F. Y., Hong, J. J., Hurt, K. J., Bae, S. S., Suh, P. G. & Snyder, S. H. (2002) Nature 415, 541-544.
17. Rong, R., Ahn, J. Y., Huang, H., Nagata, E., Kalman, D., Kapp, J. A., Tu, J., Worley, P. F., Snyder, S. H. & Ye, K. (2003) Nat. Neurosci. 6, 1153-1161.
18. Ye, K., Compton, D. A., Lai, M. M., Walensky, L. D. & Snyder, S. H. (1999) J. Neurosci. 19, 10747-10756.
19. Ye, K., Ke, Y., Keshava, N., Shanks, J., Kapp, J. A., Tekmal, R. R., Petros, J. & Joshi, H. C. (1998) Proc. Natl. Acad. Sci. USA 95, 1601-1606.
20. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W. & Vogelstein, B. (1998) Proc. Natl. Acad. Sci. USA 95, 2509-2514.
21. Ahn, J. Y., Rong, R., Kroll, T. G., Van Meir, E. G., Snyder, S. H. & Ye, K. (2004) J. Biol. Chem. 279, 16441-16451.
22. Shaw, R. J., McClatchey, A. I. & Jacks, T. (1998) J. Biol. Chem. 273, 7757-7764.
23. Schulze, K. M., Hanemann, C. O., Muller, H. W. & Hanenberg, H. (2002) Hum. Mol. Genet. 11, 69-76.
24. Kissil, J. L., Johnson, K. C., Eckman, M. S. & Jacks, T. (2002) J. Biol. Chem. 277, 10394-10399.
25. Xiao, G. H., Beeser, A., Chernoff, J. & Testa, J. R. (2002) J. Biol. Chem. 277, 883-886.
26. Surace, E. I., Haipek, C. A. & Gutmann, D. H. (2004) Oncogene 23, 580-587.
27. Sainio, M., Zhao, F., Heiska, L., Turunen, O., den Bakker, M., Zwarthoff, E., Lutchman, M., Rouleau, G. A., Jaaskelainen, J., Vaheri, A. & Carpen, O. (1997) J. Cell. Sci. 110, 2249-2260.
28. Morrison, H., Sherman, L. S., Legg, J., Banine, F., Isacke, C., Haipek, C. A., Gutmann, D. H., Ponta, H. & Herrlich, P. (2001) Genes Dev. 15, 968-980.
29. Scoles, D. R., Huynh, D. P., Morcos, P. A., Coulsell, E. R., Robinson, N. G., Tamanoi, F. & Pulst, S. M. (1998) Nat. Genet. 18, 354-359.
30. Goutebroze, L., Brault, E., Muchardt, C., Camonis, J. & Thomas, G. (2000) Mol. Cell. Biol. 20, 1699-1712.
31. Scoles, D. R., Huynh, D. P., Chen, M. S., Burke, S. P., Gutmann, D. H. & Pulst, S. M. (2000) Hum. Mol. Genet. 9, 1567-1574.
32. Murthy, A., Gonzalez-Agosti, C., Cordero, E., Pinney, D., Candia, C., Solomon, F., Gusella, J. & Ramesh, V. (1998) J. Biol. Chem. 273, 1273-1276.
33. Obremski, V. J., Hall, A. M. & Fernandez-Valle, C. (1998) J. Neurobiol. 37, 487-501.
34. Krasnoselsky, A., Massay, M. J., DeFrances, M. C., Michalopoulos, G., Zarnegar, R. & Ratner, N. (1994) J. Neurosci. 14, 7284-7290.
35. Shaw, R. J., Paez, J. G., Curto, M., Yaktine, A., Pruitt, W. M., Saotome, I., O'Bryan, J. P., Gupta, V., Ratner, N., Der, C. J., et al. (2001) Dev. Cell 1, 63-72.
36. Kissil, J. L., Wilker, E. W., Johnson, K. C., Eckman, M. S., Yaffe, M. B. & Jacks, T. (2003) Mol. Cell 12, 841-849.
37. Hirokawa, Y., Tikoo, A., Huynh, J., Utermark, T., Hanemann, C. O., Giovannini, M., Xiao, G. H., Testa, J. R., Wood, J. & Maruta, H. (2004) Cancer J. 10, 20-26.
38. Lim, J. Y., Kim, H., Kim, Y. H., Kim, S. W., Huh, P. W., Lee, K. H., Jeun, S. S., Rha, H. K. & Kang, J. K. (2003) Biochem. Biophys. Res. Commun. 302, 238-245.
39. Gautreau, A., Poullet, P., Louvard, D. & Arpin, M. (1999) Proc. Natl. Acad. Sci. USA 96, 7300-7305.
40. Kondo, T., Takeuchi, K., Doi, Y., Yonemura, S., Nagata, S. & Tsukita, S. (1997) J. Cell Biol. 139, 749-758.