-
1
-
-
15244350607
-
The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050
-
Hodgson J.T., McElvenny D.M., Darnton A.J., Price M.J., Peto J. The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050. Br J Cancer 2005, 92:587-593.
-
(2005)
Br J Cancer
, vol.92
, pp. 587-593
-
-
Hodgson, J.T.1
McElvenny, D.M.2
Darnton, A.J.3
Price, M.J.4
Peto, J.5
-
4
-
-
0026741321
-
Latent period for malignant mesothelioma of occupational origin
-
Lanphear B.P., Buncher C.R. Latent period for malignant mesothelioma of occupational origin. J Occup Med 1992, 34:718-721.
-
(1992)
J Occup Med
, vol.34
, pp. 718-721
-
-
Lanphear, B.P.1
Buncher, C.R.2
-
5
-
-
0030764560
-
The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas
-
De Luca A., Baldi A., Esposito V., et al. The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas. Nat Med 1997, 3:913-916.
-
(1997)
Nat Med
, vol.3
, pp. 913-916
-
-
De Luca, A.1
Baldi, A.2
Esposito, V.3
-
6
-
-
0032532389
-
A multi-institutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas
-
Testa J.R., Carbone M., Hirvonen A., et al. A multi-institutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas. Cancer Res 1998, 58:4505-4509.
-
(1998)
Cancer Res
, vol.58
, pp. 4505-4509
-
-
Testa, J.R.1
Carbone, M.2
Hirvonen, A.3
-
7
-
-
33744913033
-
Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey
-
Dogan A.U., Baris Y.I., Dogan M., et al. Genetic predisposition to fiber carcinogenesis causes a mesothelioma epidemic in Turkey. Cancer Res 2006, 66:5063-5068.
-
(2006)
Cancer Res
, vol.66
, pp. 5063-5068
-
-
Dogan, A.U.1
Baris, Y.I.2
Dogan, M.3
-
8
-
-
0035835437
-
Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey
-
Roushdy-Hammady I., Siegel J., Emri S., Testa J.R., Carbone M. Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey. Lancet 2001, 357:444-445.
-
(2001)
Lancet
, vol.357
, pp. 444-445
-
-
Roushdy-Hammady, I.1
Siegel, J.2
Emri, S.3
Testa, J.R.4
Carbone, M.5
-
9
-
-
0034777549
-
Therapeutic outcome according to histologic subtype in 121 patients with malignant pleural mesothelioma
-
Ceresoli G.L., Locati L.D., Ferreri A.J., et al. Therapeutic outcome according to histologic subtype in 121 patients with malignant pleural mesothelioma. Lung Cancer 2001, 34:279-287.
-
(2001)
Lung Cancer
, vol.34
, pp. 279-287
-
-
Ceresoli, G.L.1
Locati, L.D.2
Ferreri, A.J.3
-
10
-
-
77954317620
-
Group ObotEGW. Malignant pleural mesothelioma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
-
Stahel R.A., Weder W., Lievens Y., Felip E. Group ObotEGW. Malignant pleural mesothelioma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010, 21:v126-v128.
-
(2010)
Ann Oncol
, vol.21
-
-
Stahel, R.A.1
Weder, W.2
Lievens, Y.3
Felip, E.4
-
11
-
-
0041629528
-
Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
-
Vogelzang N.J., Rusthoven J.J., Symanowski J., et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 2003, 21:2636-2644.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2636-2644
-
-
Vogelzang, N.J.1
Rusthoven, J.J.2
Symanowski, J.3
-
12
-
-
27244447448
-
Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European organisation for research and treatment of cancer lung cancer group and the national cancer institute of Canada
-
van Meerbeeck J.P., Gaafar R., Manegold C., et al. Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European organisation for research and treatment of cancer lung cancer group and the national cancer institute of Canada. J Clin Oncol 2005, 23:6881-6889.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6881-6889
-
-
van Meerbeeck, J.P.1
Gaafar, R.2
Manegold, C.3
-
13
-
-
0001047311
-
Purification of a nerve-growth promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum
-
Cohen S. Purification of a nerve-growth promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum. Proc Natl Acad Sci USA 1960;46:302-11.
-
(1960)
Proc Natl Acad Sci USA
, vol.46
, pp. 302-11
-
-
Cohen, S.1
-
14
-
-
0016592056
-
Characterization of the binding of I25l-labeled epidermal growth factor to human fibroblasts
-
Carpenter G.K.J.L., Morrison M.M., Cohen S. Characterization of the binding of I25l-labeled epidermal growth factor to human fibroblasts. J Biol Chem 1975, 250:4297-4304.
-
(1975)
J Biol Chem
, vol.250
, pp. 4297-4304
-
-
Carpenter, G.K.J.L.1
Morrison, M.M.2
Cohen, S.3
-
15
-
-
0020068317
-
A native 170, 000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles
-
Cohen S., Ushiro H., Stoscheck C., Chinkers M. A native 170, 000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles. J Biol Chem 1982, 257:1523-1531.
-
(1982)
J Biol Chem
, vol.257
, pp. 1523-1531
-
-
Cohen, S.1
Ushiro, H.2
Stoscheck, C.3
Chinkers, M.4
-
16
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
-
Downward J., Yarden Y., Mayes E., et al. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature 1984, 307:521-527.
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
-
17
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon D.S., Brandt R., Ciardiello F., Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995, 19:183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
18
-
-
33745828702
-
EGF-ERBB signalling: towards the systems level
-
Citri A., Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006, 7:505-516.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
19
-
-
18344390418
-
ERBB receptors and cancer: the complexity of targeted inhibitors
-
Hynes N.E., Lane H.A. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005, 5:341-354.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
20
-
-
0035901570
-
Epidermal growth factor receptor signaling
-
Bogdan S., Klambt C. Epidermal growth factor receptor signaling. Curr Biol 2001, 11:R292-R295.
-
(2001)
Curr Biol
, vol.11
-
-
Bogdan, S.1
Klambt, C.2
-
21
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F., Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008, 358:1160-1174.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
22
-
-
0036118262
-
Epidermal growth factor receptor family in lung cancer and premalignancy
-
Franklin W.A., Veve R., Hirsch F.R., Helfrich B.A., Bunn P.A. Epidermal growth factor receptor family in lung cancer and premalignancy. Seminars in Oncology 2002, 29:3-14.
-
(2002)
Seminars in Oncology
, vol.29
, pp. 3-14
-
-
Franklin, W.A.1
Veve, R.2
Hirsch, F.R.3
Helfrich, B.A.4
Bunn, P.A.5
-
23
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V., Baselga J., Cordon-Cardo C., et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 1993, 53:2379-2385.
-
(1993)
Cancer Res
, vol.53
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
-
24
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis
-
Hirsch F.R., Varella-Garcia M., Bunn P.A., et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003, 21:3798-3807.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn, P.A.3
-
25
-
-
32544443644
-
Survival impact of epidermal growth factor receptor overexpression in patients with non-small cell lung cancer: a meta-analysis
-
Nakamura H., Kawasaki N., Taguchi M., Kabasawa K. Survival impact of epidermal growth factor receptor overexpression in patients with non-small cell lung cancer: a meta-analysis. Thorax 2006, 61:140-145.
-
(2006)
Thorax
, vol.61
, pp. 140-145
-
-
Nakamura, H.1
Kawasaki, N.2
Taguchi, M.3
Kabasawa, K.4
-
26
-
-
12144287534
-
United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets
-
Cohen M.H., Williams G.A., Sridhara R., et al. United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res 2004, 10:1212-1218.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1212-1218
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
-
27
-
-
0043210670
-
FDA drug approval summary: gefitinib (ZD1839) (Iressa(R)) tablets
-
Cohen M.H., Williams G.A., Sridhara R., Chen G., Pazdur R. FDA drug approval summary: gefitinib (ZD1839) (Iressa(R)) tablets. Oncologist 2003, 8:303-306.
-
(2003)
Oncologist
, vol.8
, pp. 303-306
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
Chen, G.4
Pazdur, R.5
-
28
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Fukuoka M., Yano S., Giaccone G., et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003, 21:2237-2246.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
-
29
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial
-
Kris M.G., Natale R.B., Herbst R.S., et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003, 290:2149-2158.
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
30
-
-
24644458654
-
FDA drug approval summary: erlotinib (Tarceva(R)) tablets
-
Cohen M.H., Johnson J.R., Chen Y.-F., Sridhara R., Pazdur R. FDA drug approval summary: erlotinib (Tarceva(R)) tablets. Oncologist 2005, 10:461-466.
-
(2005)
Oncologist
, vol.10
, pp. 461-466
-
-
Cohen, M.H.1
Johnson, J.R.2
Chen, Y.-F.3
Sridhara, R.4
Pazdur, R.5
-
31
-
-
4344646459
-
Determinants of Tumor Response and Survival With Erlotinib in Patients With Non-Small-Cell Lung Cancer
-
Perez-Soler R., Chachoua A., Hammond L.A., et al. Determinants of Tumor Response and Survival With Erlotinib in Patients With Non-Small-Cell Lung Cancer. J Clin Oncol 2004, 22:3238-3247.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
-
32
-
-
22044445517
-
Erlotinib in Previously Treated Non-Small-Cell Lung Cancer
-
Shepherd F.A., Rodrigues Pereira J., Ciuleanu T., et al. Erlotinib in Previously Treated Non-Small-Cell Lung Cancer. N Engl J Med 2005, 353:123-132.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
33
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N., Chang A., Parikh P., et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). The Lancet 2005, 366:1527-1537.
-
(2005)
The Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
-
34
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2
-
Herbst R.S., Giaccone G., Schiller J.H., et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2. J Clin Oncol 2004, 22:785-794.
-
(2004)
J Clin Oncol
, vol.22
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
-
35
-
-
22044438962
-
Asian ethnicity and adenocarcinoma histology continues to predict response to gefitinib in patients treated for advanced non-small cell carcinoma of the lung in North America
-
Ho C., Murray N., Laskin J., Melosky B., Anderson H., Bebb G. Asian ethnicity and adenocarcinoma histology continues to predict response to gefitinib in patients treated for advanced non-small cell carcinoma of the lung in North America. Lung Cancer 2005, 49:225-231.
-
(2005)
Lung Cancer
, vol.49
, pp. 225-231
-
-
Ho, C.1
Murray, N.2
Laskin, J.3
Melosky, B.4
Anderson, H.5
Bebb, G.6
-
36
-
-
1842509828
-
Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
-
Miller V.A., Kris M.G., Shah N., et al. Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 2004, 22:1103-1109.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1103-1109
-
-
Miller, V.A.1
Kris, M.G.2
Shah, N.3
-
37
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
38
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
39
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
Sharma S.V., Bell D.W., Settleman J., Haber D.A. Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 2007, 7:169-181.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
Haber, D.A.4
-
40
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H., Lin L., Takahashi T., et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005, 97:339-346.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
-
41
-
-
29144496089
-
Mutations of the epidermal growth factor receptor in non-small cell lung cancer-search and destroy
-
Chan S.K., Gullick W.J., Hill M.E. Mutations of the epidermal growth factor receptor in non-small cell lung cancer-search and destroy. Eur J Cancer 2006, 42:17-23.
-
(2006)
Eur J Cancer
, vol.42
, pp. 17-23
-
-
Chan, S.K.1
Gullick, W.J.2
Hill, M.E.3
-
42
-
-
33847406095
-
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity
-
Yun C.H., Boggon T.J., Li Y., et al. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell 2007, 11:217-227.
-
(2007)
Cancer Cell
, vol.11
, pp. 217-227
-
-
Yun, C.H.1
Boggon, T.J.2
Li, Y.3
-
43
-
-
4644274700
-
Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?
-
Gazdar A.F., Shigematsu H., Herz J., Minna J.D. Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?. Trends Mol Med 2004, 10:481-486.
-
(2004)
Trends Mol Med
, vol.10
, pp. 481-486
-
-
Gazdar, A.F.1
Shigematsu, H.2
Herz, J.3
Minna, J.D.4
-
44
-
-
5644293135
-
Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255
-
Tracy S., Mukohara T., Hansen M., Meyerson M., Johnson B.E., Janne P.A. Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255. Cancer Res 2004, 64:7241-7244.
-
(2004)
Cancer Res
, vol.64
, pp. 7241-7244
-
-
Tracy, S.1
Mukohara, T.2
Hansen, M.3
Meyerson, M.4
Johnson, B.E.5
Janne, P.A.6
-
45
-
-
17844390172
-
Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions
-
Pao W., Miller V.A. Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions. J Clin Oncol 2005, 23:2556-2568.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2556-2568
-
-
Pao, W.1
Miller, V.A.2
-
46
-
-
74949117339
-
Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer
-
Dahabreh I.J., Linardou H., Siannis F., Kosmidis P., Bafaloukos D., Murray S. Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 2010, 16:291-303.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 291-303
-
-
Dahabreh, I.J.1
Linardou, H.2
Siannis, F.3
Kosmidis, P.4
Bafaloukos, D.5
Murray, S.6
-
47
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok T.S., Wu Y.-L., Thongprasert S., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361:947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.-L.2
Thongprasert, S.3
-
48
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H., Dahabreh I.J., Kanaloupiti D., et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008, 9:962-972.
-
(2008)
Lancet Oncol
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
-
49
-
-
77957205044
-
Predictive and prognostic value of KRAS mutations in metastatic colorectal cancer patients treated with cetuximab: a meta-analysis of 22 studies
-
Qiu L.-X., Mao C., Zhang J., et al. Predictive and prognostic value of KRAS mutations in metastatic colorectal cancer patients treated with cetuximab: a meta-analysis of 22 studies. European Journal of Cancer 2010, 46:2781-2787.
-
(2010)
European Journal of Cancer
, vol.46
, pp. 2781-2787
-
-
Qiu, L.-X.1
Mao, C.2
Zhang, J.3
-
50
-
-
33144481184
-
Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancer
-
Robert F., Blumenschein G., Herbst R.S., et al. Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancer. J Clin Oncol 2005, 23:9089-9096.
-
(2005)
J Clin Oncol
, vol.23
, pp. 9089-9096
-
-
Robert, F.1
Blumenschein, G.2
Herbst, R.S.3
-
51
-
-
37649022615
-
Randomized phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer
-
Butts C.A., Bodkin D., Middleman E.L., et al. Randomized phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer. J Clin Oncol 2007, 25:5777-5784.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5777-5784
-
-
Butts, C.A.1
Bodkin, D.2
Middleman, E.L.3
-
52
-
-
38849114239
-
Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer
-
Rosell R., Robinet G., Szczesna A., et al. Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-line therapy in EGFR-expressing advanced non-small-cell lung cancer. Ann Oncol 2008, 19:362-369.
-
(2008)
Ann Oncol
, vol.19
, pp. 362-369
-
-
Rosell, R.1
Robinet, G.2
Szczesna, A.3
-
53
-
-
77952542715
-
Emerging profile of cetuximab in non-small cell lung cancer
-
Ettinger D.S. Emerging profile of cetuximab in non-small cell lung cancer. Lung cancer 2010, 68:332-337.
-
(2010)
Lung cancer
, vol.68
, pp. 332-337
-
-
Ettinger, D.S.1
-
54
-
-
65349116059
-
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
-
Pirker R., Pereira J.R., Szczesna A., et al. Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial. The Lancet 2009, 373:1525-1531.
-
(2009)
The Lancet
, vol.373
, pp. 1525-1531
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
-
55
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
Saltz L.B., Meropol N.J., Loehrer P.J., Needle M.N., Kopit J., Mayer R.J. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004, 22:1201-1208.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer, P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
56
-
-
33750615769
-
Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
-
Lenz H.J., Van Cutsem E., Khambata-Ford S., et al. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol 2006, 24:4914-4921.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4914-4921
-
-
Lenz, H.J.1
Van Cutsem, E.2
Khambata-Ford, S.3
-
57
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D., Humblet Y., Siena S., et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004, 351:337-345.
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
58
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
-
Van Cutsem E., Peeters M., Siena S., et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007, 25:1658-1664.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
-
59
-
-
36749067866
-
Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer
-
Tabernero J., Van Cutsem E., Diaz-Rubio E., et al. Phase II trial of cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2007, 25:5225-5232.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5225-5232
-
-
Tabernero, J.1
Van Cutsem, E.2
Diaz-Rubio, E.3
-
60
-
-
33644697486
-
Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma
-
Folprecht G., Lutz M.P., Schoffski P., et al. Cetuximab and irinotecan/5-fluorouracil/folinic acid is a safe combination for the first-line treatment of patients with epidermal growth factor receptor expressing metastatic colorectal carcinoma. Ann Oncol 2006, 17:450-456.
-
(2006)
Ann Oncol
, vol.17
, pp. 450-456
-
-
Folprecht, G.1
Lutz, M.P.2
Schoffski, P.3
-
61
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CAmutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
-
De Roock W., Claes B., Bernasconi D., et al. Effects of KRAS, BRAF, NRAS, and PIK3CAmutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. The Lancet Oncology 2010, 11:753-762.
-
(2010)
The Lancet Oncology
, vol.11
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
-
63
-
-
0035444798
-
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study
-
Andreyev H.J., Norman A.R., Cunningham D., et al. Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer 2001, 85:692-696.
-
(2001)
Br J Cancer
, vol.85
, pp. 692-696
-
-
Andreyev, H.J.1
Norman, A.R.2
Cunningham, D.3
-
64
-
-
78049443211
-
Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies
-
Hawkes E., Cunningham D. Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies. Journal of Clinical Oncology 2010, 28:e529-e531.
-
(2010)
Journal of Clinical Oncology
, vol.28
-
-
Hawkes, E.1
Cunningham, D.2
-
65
-
-
73349094741
-
Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer
-
Laurent-Puig P., Cayre A., Manceau G., et al. Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer. Journal of Clinical Oncology 2009, 27:5924-5930.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 5924-5930
-
-
Laurent-Puig, P.1
Cayre, A.2
Manceau, G.3
-
66
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H., Bignell G.R., Cox C., et al. Mutations of the BRAF gene in human cancer. Nature 2002, 417:949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
67
-
-
0037112438
-
Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia
-
Yuen S.T., Davies H., Chan T.L., et al. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 2002, 62:6451-6455.
-
(2002)
Cancer Res
, vol.62
, pp. 6451-6455
-
-
Yuen, S.T.1
Davies, H.2
Chan, T.L.3
-
68
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
Di Nicolantonio F., Martini M., Molinari F., et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008, 26:5705-5712.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
-
69
-
-
68749119351
-
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
Loupakis F., Ruzzo A., Cremolini C., et al. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer 2009, 101:715-721.
-
(2009)
Br J Cancer
, vol.101
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
-
70
-
-
67649652208
-
BRAF mutation in metastatic colorectal cancer
-
Tol J., Nagtegaal I.D., Punt C.J. BRAF mutation in metastatic colorectal cancer. N Engl J Med 2009, 361:98-99.
-
(2009)
N Engl J Med
, vol.361
, pp. 98-99
-
-
Tol, J.1
Nagtegaal, I.D.2
Punt, C.J.3
-
71
-
-
77951945506
-
Status of PI3K inhibition and biomarker development in cancer therapeutics
-
Markman B., Atzori F., Pérez-García J., Tabernero J., Baselga J. Status of PI3K inhibition and biomarker development in cancer therapeutics. Annals of Oncology 2010, 21:683-691.
-
(2010)
Annals of Oncology
, vol.21
, pp. 683-691
-
-
Markman, B.1
Atzori, F.2
Pérez-García, J.3
Tabernero, J.4
Baselga, J.5
-
72
-
-
59049089201
-
PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
-
Perrone F., Lampis A., Orsenigo M., et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients. Ann Oncol 2009, 20:84-90.
-
(2009)
Ann Oncol
, vol.20
, pp. 84-90
-
-
Perrone, F.1
Lampis, A.2
Orsenigo, M.3
-
73
-
-
62449302407
-
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
-
Sartore-Bianchi A., Martini M., Molinari F., et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res 2009, 69:1851-1857.
-
(2009)
Cancer Res
, vol.69
, pp. 1851-1857
-
-
Sartore-Bianchi, A.1
Martini, M.2
Molinari, F.3
-
74
-
-
77956236877
-
PI(3)king apart PTEN's role in cancer
-
Zhang S., Yu D. PI(3)king apart PTEN's role in cancer. Clinical Cancer Research 2010, 16:4325-4330.
-
(2010)
Clinical Cancer Research
, vol.16
, pp. 4325-4330
-
-
Zhang, S.1
Yu, D.2
-
75
-
-
35348908314
-
PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients
-
Frattini M., Saletti P., Romagnani E., et al. PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients. Br J Cancer 2007, 97:1139-1145.
-
(2007)
Br J Cancer
, vol.97
, pp. 1139-1145
-
-
Frattini, M.1
Saletti, P.2
Romagnani, E.3
-
76
-
-
77949435827
-
Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
-
Bardelli A., Siena S. Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer. Journal of Clinical Oncology 2010, 28:1254-1261.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 1254-1261
-
-
Bardelli, A.1
Siena, S.2
-
77
-
-
77956190650
-
Tissue and serum EGFR as prognostic factors in malignant pleural mesothelioma
-
Gaafar R., Bahnassy A., Abdelsalam I., et al. Tissue and serum EGFR as prognostic factors in malignant pleural mesothelioma. Lung Cancer 2010, 70:43-50.
-
(2010)
Lung Cancer
, vol.70
, pp. 43-50
-
-
Gaafar, R.1
Bahnassy, A.2
Abdelsalam, I.3
-
78
-
-
50249128105
-
Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma
-
Okuda K., Sasaki H., Kawano O., et al. Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma. J Cancer Res Clin Oncol 2008, 134:1105-1111.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 1105-1111
-
-
Okuda, K.1
Sasaki, H.2
Kawano, O.3
-
79
-
-
31344449869
-
EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinico-pathological correlations
-
Destro A., Ceresoli G.L., Falleni M., et al. EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinico-pathological correlations. Lung Cancer 2006, 51:207-215.
-
(2006)
Lung Cancer
, vol.51
, pp. 207-215
-
-
Destro, A.1
Ceresoli, G.L.2
Falleni, M.3
-
80
-
-
3142752597
-
Clinico-pathological and biological prognostic factors in pleural malignant mesothelioma
-
O'Byrne K.J., Edwards J.G., Waller D.A. Clinico-pathological and biological prognostic factors in pleural malignant mesothelioma. Lung Cancer 2004, 45(Suppl. 1):S45-S48.
-
(2004)
Lung Cancer
, vol.45
, Issue.SUPPL. 1
-
-
O'Byrne, K.J.1
Edwards, J.G.2
Waller, D.A.3
-
81
-
-
0025330611
-
Malignant pleural mesothelioma and epidermal growth factor receptor (EGF-R). Relationship of EGF-R with histology and survival using fixed paraffin embedded tissue and the F4, monoclonal antibody
-
Dazzi H., Hasleton P.S., Thatcher N., Wilkes S., Swindell R., Chatterjee A.K. Malignant pleural mesothelioma and epidermal growth factor receptor (EGF-R). Relationship of EGF-R with histology and survival using fixed paraffin embedded tissue and the F4, monoclonal antibody. Br J Cancer 1990, 61:924-926.
-
(1990)
Br J Cancer
, vol.61
, pp. 924-926
-
-
Dazzi, H.1
Hasleton, P.S.2
Thatcher, N.3
Wilkes, S.4
Swindell, R.5
Chatterjee, A.K.6
-
82
-
-
33750313674
-
EGFR expression: associations with outcome and clinicopathological variables in malignant pleural mesothelioma
-
Edwards J.G., Swinson D.E., Jones J.L., Waller D.A., O'Byrne K.J. EGFR expression: associations with outcome and clinicopathological variables in malignant pleural mesothelioma. Lung Cancer 2006, 54:399-407.
-
(2006)
Lung Cancer
, vol.54
, pp. 399-407
-
-
Edwards, J.G.1
Swinson, D.E.2
Jones, J.L.3
Waller, D.A.4
O'Byrne, K.J.5
-
83
-
-
0037105665
-
Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma
-
Janne P.A., Taffaro M.L., Salgia R., Johnson B.E. Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma. Cancer Res 2002, 62:5242-5247.
-
(2002)
Cancer Res
, vol.62
, pp. 5242-5247
-
-
Janne, P.A.1
Taffaro, M.L.2
Salgia, R.3
Johnson, B.E.4
-
84
-
-
18244363577
-
The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro
-
Cole G.W., Alleva A.M., Reddy R.M., et al. The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro. J Thorac Cardiovasc Surg 2005, 129:1010-1017.
-
(2005)
J Thorac Cardiovasc Surg
, vol.129
, pp. 1010-1017
-
-
Cole, G.W.1
Alleva, A.M.2
Reddy, R.M.3
-
85
-
-
16844372990
-
Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B
-
Govindan R., Kratzke R.A., Herndon J.E., et al. Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. Clin Cancer Res 2005, 11:2300-2304.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2300-2304
-
-
Govindan, R.1
Kratzke, R.A.2
Herndon, J.E.3
-
86
-
-
0031887839
-
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B
-
Herndon J.E., Green M.R., Chahinian A.P., Corson J.M., Suzuki Y., Vogelzang N.J. Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B. Chest 1998, 113:723-731.
-
(1998)
Chest
, vol.113
, pp. 723-731
-
-
Herndon, J.E.1
Green, M.R.2
Chahinian, A.P.3
Corson, J.M.4
Suzuki, Y.5
Vogelzang, N.J.6
-
87
-
-
34347273808
-
Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study
-
Garland L.L., Rankin C., Gandara D.R., et al. Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study. J Clin Oncol 2007, 25:2406-2413.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2406-2413
-
-
Garland, L.L.1
Rankin, C.2
Gandara, D.R.3
-
88
-
-
28844461559
-
Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma
-
Cortese J.F., Gowda A.L., Wali A., Eliason J.F., Pass H.I., Everson R.B. Common EGFR mutations conferring sensitivity to gefitinib in lung adenocarcinoma are not prevalent in human malignant mesothelioma. Int J Cancer 2006, 118:521-522.
-
(2006)
Int J Cancer
, vol.118
, pp. 521-522
-
-
Cortese, J.F.1
Gowda, A.L.2
Wali, A.3
Eliason, J.F.4
Pass, H.I.5
Everson, R.B.6
-
89
-
-
0026682649
-
P53 and Kirsten-ras mutations in human mesothelioma cell lines
-
Metcalf R.A., Welsh J.A., Bennett W.P., et al. P53 and Kirsten-ras mutations in human mesothelioma cell lines. Cancer Res 1992, 52:2610-2615.
-
(1992)
Cancer Res
, vol.52
, pp. 2610-2615
-
-
Metcalf, R.A.1
Welsh, J.A.2
Bennett, W.P.3
-
90
-
-
0031936707
-
Assessment of mutations of Ha- and Ki-ras oncogenes and the p53 suppressor gene in seven malignant mesothelioma patients exposed to asbestos-PCR-SSCP and sequencing analyses of paraffin-embedded primary tumors
-
Kitamura F., Araki S., Tanigawa T., Miura H., Akabane H., Iwasaki R. Assessment of mutations of Ha- and Ki-ras oncogenes and the p53 suppressor gene in seven malignant mesothelioma patients exposed to asbestos-PCR-SSCP and sequencing analyses of paraffin-embedded primary tumors. Ind Health 1998, 36:52-56.
-
(1998)
Ind Health
, vol.36
, pp. 52-56
-
-
Kitamura, F.1
Araki, S.2
Tanigawa, T.3
Miura, H.4
Akabane, H.5
Iwasaki, R.6
-
91
-
-
0036257247
-
Assessment of the mutations of p53 suppressor gene and Ha- and Ki-ras oncogenes in malignant mesothelioma in relation to asbestos exposure: a study of 12 American patients
-
Kitamura F., Araki S., Suzuki Y., Yokoyama K., Tanigawa T., Iwasaki R. Assessment of the mutations of p53 suppressor gene and Ha- and Ki-ras oncogenes in malignant mesothelioma in relation to asbestos exposure: a study of 12 American patients. Ind Health 2002, 40:175-181.
-
(2002)
Ind Health
, vol.40
, pp. 175-181
-
-
Kitamura, F.1
Araki, S.2
Suzuki, Y.3
Yokoyama, K.4
Tanigawa, T.5
Iwasaki, R.6
-
92
-
-
0034702353
-
Analysis of K-ras and p53 mutations in mesotheliomas from humans and rats exposed to asbestos
-
Ni Z., Liu Y., Keshava N., Zhou G., Whong W., Ong T. Analysis of K-ras and p53 mutations in mesotheliomas from humans and rats exposed to asbestos. Mutat Res 2000, 468:87-92.
-
(2000)
Mutat Res
, vol.468
, pp. 87-92
-
-
Ni, Z.1
Liu, Y.2
Keshava, N.3
Zhou, G.4
Whong, W.5
Ong, T.6
-
93
-
-
3242810674
-
Mutation analysis of the BRAF codon 599 in malignant pleural mesothelioma by enriched PCR-RFLP
-
Dote H., Tsukuda K., Toyooka S., Yano M., Pass H.I., Shimizu N. Mutation analysis of the BRAF codon 599 in malignant pleural mesothelioma by enriched PCR-RFLP. Oncol Rep 2004, 11:361-363.
-
(2004)
Oncol Rep
, vol.11
, pp. 361-363
-
-
Dote, H.1
Tsukuda, K.2
Toyooka, S.3
Yano, M.4
Pass, H.I.5
Shimizu, N.6
-
94
-
-
67650099861
-
Activation of the PI3K-AKT pathway in human malignant mesothelioma cells
-
Yutaro Suzuki, Hideki Murakami, Koji Kawaguchi, et al. Activation of the PI3K-AKT pathway in human malignant mesothelioma cells. Mol Med Rep 2009, 2:181-188.
-
(2009)
Mol Med Rep
, vol.2
, pp. 181-188
-
-
Yutaro, S.1
Hideki, M.2
Koji, K.3
-
95
-
-
24944539840
-
Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth
-
Altomare D.A., You H., Xiao G.H., et al. Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth. Oncogene 2005, 24:6080-6089.
-
(2005)
Oncogene
, vol.24
, pp. 6080-6089
-
-
Altomare, D.A.1
You, H.2
Xiao, G.H.3
-
96
-
-
39149121845
-
PTEN expression is a strong predictor of survival in mesothelioma patients
-
Opitz I., Soltermann A., Abaecherli M., et al. PTEN expression is a strong predictor of survival in mesothelioma patients. Eur J Cardiothorac Surg 2008, 33:502-506.
-
(2008)
Eur J Cardiothorac Surg
, vol.33
, pp. 502-506
-
-
Opitz, I.1
Soltermann, A.2
Abaecherli, M.3
-
97
-
-
70349739221
-
The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer
-
Kono S.A., Marshall M.E., Ware K.E., Heasley L.E. The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer. Drug Resist Updat 2009, 12:95-102.
-
(2009)
Drug Resist Updat
, vol.12
, pp. 95-102
-
-
Kono, S.A.1
Marshall, M.E.2
Ware, K.E.3
Heasley, L.E.4
-
98
-
-
57349116915
-
Mechanisms of resistance to EGFR tyrosine kinase inhibitors: implications for patient selection and drug combination strategies
-
Eyzaguirre A., Buck E., Iwata K., Haley J., Miglarese M. Mechanisms of resistance to EGFR tyrosine kinase inhibitors: implications for patient selection and drug combination strategies. Target Oncol 2008, 3:235-243.
-
(2008)
Target Oncol
, vol.3
, pp. 235-243
-
-
Eyzaguirre, A.1
Buck, E.2
Iwata, K.3
Haley, J.4
Miglarese, M.5
-
99
-
-
49649127657
-
Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
-
Engelman J.A., Janne P.A. Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 2008, 14:2895-2899.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2895-2899
-
-
Engelman, J.A.1
Janne, P.A.2
-
100
-
-
31544482729
-
Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma
-
Jagadeeswaran R., Ma P.C., Seiwert T.Y., et al. Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma. Cancer Res 2006, 66:352-361.
-
(2006)
Cancer Res
, vol.66
, pp. 352-361
-
-
Jagadeeswaran, R.1
Ma, P.C.2
Seiwert, T.Y.3
-
101
-
-
5644280150
-
Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes
-
Hoang C.D., Zhang X., Scott P.D., et al. Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes. Cancer Res 2004, 64:7479-7485.
-
(2004)
Cancer Res
, vol.64
, pp. 7479-7485
-
-
Hoang, C.D.1
Zhang, X.2
Scott, P.D.3
-
102
-
-
33747371111
-
Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Thoracic surgery directors association resident research award
-
[discussion-2]
-
Whitson B.A., Jacobson B.A., Frizelle S., et al. Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Thoracic surgery directors association resident research award. Ann Thorac Surg 2006, 82:996-1001. [discussion-2].
-
(2006)
Ann Thorac Surg
, vol.82
, pp. 996-1001
-
-
Whitson, B.A.1
Jacobson, B.A.2
Frizelle, S.3
-
103
-
-
63449104490
-
Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
-
Kai K., D'Costa S., Sills R.C., Kim Y. Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines. Cancer Lett 2009, 278:49-55.
-
(2009)
Cancer Lett
, vol.278
, pp. 49-55
-
-
Kai, K.1
D'Costa, S.2
Sills, R.C.3
Kim, Y.4
-
104
-
-
13744254574
-
Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention
-
Dannenberg A.J., Lippman S.M., Mann J.R., Subbaramaiah K., DuBois R.N. Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention. J Clin Oncol 2005, 23:254-266.
-
(2005)
J Clin Oncol
, vol.23
, pp. 254-266
-
-
Dannenberg, A.J.1
Lippman, S.M.2
Mann, J.R.3
Subbaramaiah, K.4
DuBois, R.N.5
-
105
-
-
27644555091
-
Cyclooxygenase-2: how good is it as a target for cancer chemoprevention?
-
Hull M.A. Cyclooxygenase-2: how good is it as a target for cancer chemoprevention?. Eur J Cancer 2005, 41:1854-1863.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1854-1863
-
-
Hull, M.A.1
-
106
-
-
23844462448
-
Role of COX-2 selective inhibitors for prevention and treatment of cancer
-
Amir M., Agarwal H.K. Role of COX-2 selective inhibitors for prevention and treatment of cancer. Pharmazie 2005, 60:563-570.
-
(2005)
Pharmazie
, vol.60
, pp. 563-570
-
-
Amir, M.1
Agarwal, H.K.2
-
107
-
-
0141963117
-
Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?
-
Gasparini G., Longo R., Sarmiento R., Morabito A. Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?. Lancet Oncol 2003, 4:605-615.
-
(2003)
Lancet Oncol
, vol.4
, pp. 605-615
-
-
Gasparini, G.1
Longo, R.2
Sarmiento, R.3
Morabito, A.4
-
108
-
-
2442467100
-
Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma
-
Baldi A., Santini D., Vasaturo F., et al. Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma. Thorax 2004, 59:428-433.
-
(2004)
Thorax
, vol.59
, pp. 428-433
-
-
Baldi, A.1
Santini, D.2
Vasaturo, F.3
-
109
-
-
0036278887
-
Cyclooxygenase-2 expression is a novel prognostic factor in malignant mesothelioma
-
Edwards J.G., Faux S.P., Plummer S.M., et al. Cyclooxygenase-2 expression is a novel prognostic factor in malignant mesothelioma. Clin Cancer Res 2002, 8:1857-1862.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1857-1862
-
-
Edwards, J.G.1
Faux, S.P.2
Plummer, S.M.3
-
110
-
-
22144439371
-
Cyclooxygenase-2 expression predicts survival in malignant pleural mesothelioma
-
O'Kane S.L., Cawkwell L., Campbell A., Lind M.J. Cyclooxygenase-2 expression predicts survival in malignant pleural mesothelioma. Eur J Cancer 2005, 41:1645-1648.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1645-1648
-
-
O'Kane, S.L.1
Cawkwell, L.2
Campbell, A.3
Lind, M.J.4
-
111
-
-
1342330958
-
Preclinical evaluation of the nonsteroidal anti-inflammatory agent celecoxib on malignant mesothelioma chemoprevention
-
Catalano A., Graciotti L., Rinaldi L., et al. Preclinical evaluation of the nonsteroidal anti-inflammatory agent celecoxib on malignant mesothelioma chemoprevention. Int J Cancer 2004, 109:322-328.
-
(2004)
Int J Cancer
, vol.109
, pp. 322-328
-
-
Catalano, A.1
Graciotti, L.2
Rinaldi, L.3
-
112
-
-
72449176844
-
COX-2 specific inhibitors enhance the cytotoxic effects of pemetrexed in mesothelioma cell lines
-
O'Kane S.L., Eagle G.L., Greenman J., Lind M.J., Cawkwell L. COX-2 specific inhibitors enhance the cytotoxic effects of pemetrexed in mesothelioma cell lines. Lung Cancer 2010, 67:160-165.
-
(2010)
Lung Cancer
, vol.67
, pp. 160-165
-
-
O'Kane, S.L.1
Eagle, G.L.2
Greenman, J.3
Lind, M.J.4
Cawkwell, L.5
-
113
-
-
27244432279
-
Phase I study of gefitinib plus celecoxib in recurrent or metastatic squamous cell carcinoma of the head and neck
-
Wirth L.J., Haddad R.I., Lindeman N.I., et al. Phase I study of gefitinib plus celecoxib in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2005, 23:6976-6981.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6976-6981
-
-
Wirth, L.J.1
Haddad, R.I.2
Lindeman, N.I.3
-
114
-
-
34247882824
-
Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC)
-
Gadgeel S.M., Ruckdeschel J.C., Heath E.I., Heilbrun L.K., Venkatramanamoorthy R., Wozniak A. Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC). J Thorac Oncol 2007, 2:299-305.
-
(2007)
J Thorac Oncol
, vol.2
, pp. 299-305
-
-
Gadgeel, S.M.1
Ruckdeschel, J.C.2
Heath, E.I.3
Heilbrun, L.K.4
Venkatramanamoorthy, R.5
Wozniak, A.6
-
115
-
-
34548212389
-
Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non small-cell lung cancer
-
O'Byrne K.J., Danson S., Dunlop D., et al. Combination therapy with gefitinib and rofecoxib in patients with platinum-pretreated relapsed non small-cell lung cancer. J Clin Oncol 2007, 25:3266-3273.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3266-3273
-
-
O'Byrne, K.J.1
Danson, S.2
Dunlop, D.3
-
116
-
-
33745219813
-
A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer
-
Reckamp K.L., Krysan K., Morrow J.D., et al. A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. Clin Cancer Res 2006, 12:3381-3388.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3381-3388
-
-
Reckamp, K.L.1
Krysan, K.2
Morrow, J.D.3
|