-
1
-
-
63049136592
-
A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
-
M. Adorno, M. Cordenonsi, M. Montagner, S. Dupont, C. Wong, B. Hann, A. Solari, S. Bobisse, M.B. Rondina, and V. Guzzardo A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis Cell 137 2009 87 98
-
(2009)
Cell
, vol.137
, pp. 87-98
-
-
Adorno, M.1
Cordenonsi, M.2
Montagner, M.3
Dupont, S.4
Wong, C.5
Hann, B.6
Solari, A.7
Bobisse, S.8
Rondina, M.B.9
Guzzardo, V.10
-
3
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
S.J. Baker, E.R. Fearon, J.M. Nigro, S.R. Hamilton, A.C. Preisinger, J.M. Jessup, P. vanTuinen, D.H. Ledbetter, D.F. Barker, and Y. Nakamura Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas Science 244 1989 217 221
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
Fearon, E.R.2
Nigro, J.M.3
Hamilton, S.R.4
Preisinger, A.C.5
Jessup, J.M.6
Vantuinen, P.7
Ledbetter, D.H.8
Barker, D.F.9
Nakamura, Y.10
-
4
-
-
0027459198
-
Mdm2 expression is induced by wild type p53 activity
-
Y. Barak, T. Juven, R. Haffner, and M. Oren mdm2 expression is induced by wild type p53 activity EMBO Journal 12 1993 461 468
-
(1993)
EMBO Journal
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
5
-
-
70350575440
-
Modulation of intracellular ROS levels by TIGAR controls autophagy
-
K. Bensaad, E.C. Cheung, and K.H. Vousden Modulation of intracellular ROS levels by TIGAR controls autophagy EMBO Journal 28 2009 3015 3026
-
(2009)
EMBO Journal
, vol.28
, pp. 3015-3026
-
-
Bensaad, K.1
Cheung, E.C.2
Vousden, K.H.3
-
6
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
K. Bensaad, A. Tsuruta, M.A. Selak, M.N. Vidal, K. Nakano, R. Bartrons, E. Gottlieb, and K.H. Vousden TIGAR, a p53-inducible regulator of glycolysis and apoptosis Cell 126 2006 107 120
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
7
-
-
34249811206
-
Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion
-
A. Bourdon, L. Minai, V. Serre, J.P. Jais, E. Sarzi, S. Aubert, D. Chretien, P. de Lonlay, V. Paquis-Flucklinger, and H. Arakawa Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion Nature Genetics 39 2007 776 780
-
(2007)
Nature Genetics
, vol.39
, pp. 776-780
-
-
Bourdon, A.1
Minai, L.2
Serre, V.3
Jais, J.P.4
Sarzi, E.5
Aubert, S.6
Chretien, D.7
De Lonlay, P.8
Paquis-Flucklinger, V.9
Arakawa, H.10
-
8
-
-
79955795151
-
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression
-
C.A. Brady, D. Jiang, S.S. Mello, T.M. Johnson, L.A. Jarvis, M.M. Kozak, D. Kenzelmann Broz, S. Basak, E.J. Park, and M.E. McLaughlin Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression Cell 145 2011 571 583
-
(2011)
Cell
, vol.145
, pp. 571-583
-
-
Brady, C.A.1
Jiang, D.2
Mello, S.S.3
Johnson, T.M.4
Jarvis, L.A.5
Kozak, M.M.6
Kenzelmann Broz, D.7
Basak, S.8
Park, E.J.9
McLaughlin, M.E.10
-
9
-
-
0034737292
-
Drosophila p53 binds a damage response element at the reaper locus
-
M.H. Brodsky, W. Nordstrom, G. Tsang, E. Kwan, G.M. Rubin, and J.M. Abrams Drosophila p53 binds a damage response element at the reaper locus Cell 101 2000 103 113
-
(2000)
Cell
, vol.101
, pp. 103-113
-
-
Brodsky, M.H.1
Nordstrom, W.2
Tsang, G.3
Kwan, E.4
Rubin, G.M.5
Abrams, J.M.6
-
10
-
-
70349443284
-
When mutants gain new powers: News from the mutant p53 field
-
R. Brosh, and V. Rotter When mutants gain new powers: news from the mutant p53 field Nature Reviews Cancer 9 2009 701 713
-
(2009)
Nature Reviews Cancer
, vol.9
, pp. 701-713
-
-
Brosh, R.1
Rotter, V.2
-
11
-
-
0036128899
-
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
-
V.J. Bykov, N. Issaeva, A. Shilov, M. Hultcrantz, E. Pugacheva, P. Chumakov, J. Bergman, K.G. Wiman, and G. Selivanova Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound Nature Medicine 8 2002 282 288
-
(2002)
Nature Medicine
, vol.8
, pp. 282-288
-
-
Bykov, V.J.1
Issaeva, N.2
Shilov, A.3
Hultcrantz, M.4
Pugacheva, E.5
Chumakov, P.6
Bergman, J.7
Wiman, K.G.8
Selivanova, G.9
-
13
-
-
22844445705
-
Temporal dissection of p53 function in vitro and in vivo
-
M.A. Christophorou, D. Martin-Zanca, L. Soucek, E.R. Lawlor, L. Brown-Swigart, E.W. Verschuren, and G.I. Evan Temporal dissection of p53 function in vitro and in vivo Nature Genetics 37 2005 718 726
-
(2005)
Nature Genetics
, vol.37
, pp. 718-726
-
-
Christophorou, M.A.1
Martin-Zanca, D.2
Soucek, L.3
Lawlor, E.R.4
Brown-Swigart, L.5
Verschuren, E.W.6
Evan, G.I.7
-
14
-
-
33748670457
-
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
-
M.A. Christophorou, I. Ringshausen, A.J. Finch, L.B. Swigart, and G.I. Evan The pathological response to DNA damage does not contribute to p53-mediated tumour suppression Nature 443 2006 214 217
-
(2006)
Nature
, vol.443
, pp. 214-217
-
-
Christophorou, M.A.1
Ringshausen, I.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
-
15
-
-
84866488967
-
Metabolomics in cancer: A bench-to-bedside intersection
-
W.M. Claudino, P.H. Goncalves, A. di Leo, P.A. Philip, and F.H. Sarkar Metabolomics in cancer: a bench-to-bedside intersection Critical Reviews in Oncology/Hematology 84 1 2012 1 7
-
(2012)
Critical Reviews in Oncology/Hematology
, vol.84
, Issue.1
, pp. 1-7
-
-
Claudino, W.M.1
Goncalves, P.H.2
Di Leo, A.3
Philip, P.A.4
Sarkar, F.H.5
-
16
-
-
84859171807
-
MYC on the path to cancer
-
C.V. Dang MYC on the path to cancer Cell 149 2012 22 35
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
17
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
L.A. Donehower, M. Harvey, B.L. Slagle, M.J. McArthur, C.A. Montgomery Jr., J.S. Butel, and A. Bradley Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours Nature 356 1992 215 221
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, Jr.C.A.5
Butel, J.S.6
Bradley, A.7
-
18
-
-
33748674375
-
Tumour biology: Policing of oncogene activity by p53
-
A. Efeyan, I. Garcia-Cao, D. Herranz, S. Velasco-Miguel, and M. Serrano Tumour biology: policing of oncogene activity by p53 Nature 443 2006 159
-
(2006)
Nature
, vol.443
, pp. 159
-
-
Efeyan, A.1
Garcia-Cao, I.2
Herranz, D.3
Velasco-Miguel, S.4
Serrano, M.5
-
19
-
-
79951701976
-
Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells
-
S. Endo, K. Yamato, S. Hirai, T. Moriwaki, K. Fukuda, H. Suzuki, M. Abei, I. Nakagawa, and I. Hyodo Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells Cancer Science 102 2011 605 613
-
(2011)
Cancer Science
, vol.102
, pp. 605-613
-
-
Endo, S.1
Yamato, K.2
Hirai, S.3
Moriwaki, T.4
Fukuda, K.5
Suzuki, H.6
Abei, M.7
Nakagawa, I.8
Hyodo, I.9
-
20
-
-
78649491016
-
Stage-specific sensitivity to p53 restoration during lung cancer progression
-
D.M. Feldser, K.K. Kostova, M.M. Winslow, S.E. Taylor, C. Cashman, C.A. Whittaker, F.J. Sanchez-Rivera, R. Resnick, R. Bronson, and M.T. Hemann Stage-specific sensitivity to p53 restoration during lung cancer progression Nature 468 2010 572 575
-
(2010)
Nature
, vol.468
, pp. 572-575
-
-
Feldser, D.M.1
Kostova, K.K.2
Winslow, M.M.3
Taylor, S.E.4
Cashman, C.5
Whittaker, C.A.6
Sanchez-Rivera, F.J.7
Resnick, R.8
Bronson, R.9
Hemann, M.T.10
-
22
-
-
0024382760
-
The p53 proto-oncogene can act as a suppressor of transformation
-
C.A. Finlay, P.W. Hinds, and A.J. Levine The p53 proto-oncogene can act as a suppressor of transformation Cell 57 1989 1083 1093
-
(1989)
Cell
, vol.57
, pp. 1083-1093
-
-
Finlay, C.A.1
Hinds, P.W.2
Levine, A.J.3
-
23
-
-
60249085118
-
Mitochondria in cancer: Not just innocent bystanders
-
C. Frezza, and E. Gottlieb Mitochondria in cancer: not just innocent bystanders Seminars in Cancer Biology 19 2009 4 11
-
(2009)
Seminars in Cancer Biology
, vol.19
, pp. 4-11
-
-
Frezza, C.1
Gottlieb, E.2
-
24
-
-
84860389276
-
Validation of MdmX as a therapeutic target for reactivating p53 in tumors
-
D. Garcia, M.R. Warr, C.P. Martins, L. Brown Swigart, E. Passegue, and G.I. Evan Validation of MdmX as a therapeutic target for reactivating p53 in tumors Genes & Development 25 2011 1746 1757
-
(2011)
Genes & Development
, vol.25
, pp. 1746-1757
-
-
Garcia, D.1
Warr, M.R.2
Martins, C.P.3
Brown Swigart, L.4
Passegue, E.5
Evan, G.I.6
-
25
-
-
78650308849
-
Understanding wild-type and mutant p53 activities in human cancer: New landmarks on the way to targeted therapies
-
I. Goldstein, V. Marcel, M. Olivier, M. Oren, V. Rotter, and P. Hainaut Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies Cancer Gene Therapy 18 2011 2 11
-
(2011)
Cancer Gene Therapy
, vol.18
, pp. 2-11
-
-
Goldstein, I.1
Marcel, V.2
Olivier, M.3
Oren, M.4
Rotter, V.5
Hainaut, P.6
-
26
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
D.R. Green, and G. Kroemer Cytoplasmic functions of the tumour suppressor p53 Nature 458 2009 1127 1130
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
27
-
-
3042601281
-
Suppression of tumorigenesis by the p53 target PUMA
-
M.T. Hemann, J.T. Zilfou, Z. Zhao, D.J. Burgess, G.J. Hannon, and S.W. Lowe Suppression of tumorigenesis by the p53 target PUMA Proceedings of the National Academy of Sciences of the United States of America 101 2004 9333 9338
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 9333-9338
-
-
Hemann, M.T.1
Zilfou, J.T.2
Zhao, Z.3
Burgess, D.J.4
Hannon, G.J.5
Lowe, S.W.6
-
28
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
H. Hermeking MicroRNAs in the p53 network: micromanagement of tumour suppression Nature Reviews Cancer 12 2012 613 626
-
(2012)
Nature Reviews Cancer
, vol.12
, pp. 613-626
-
-
Hermeking, H.1
-
29
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
W. Hu, C. Zhang, R. Wu, Y. Sun, A. Levine, and Z. Feng Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function Proceedings of the National Academy of Sciences of the United States of America 107 2010 7455 7460
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
Zhang, C.2
Wu, R.3
Sun, Y.4
Levine, A.5
Feng, Z.6
-
30
-
-
70449093664
-
GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress
-
T. Ide, L. Brown-Endres, K. Chu, P.P. Ongusaha, T. Ohtsuka, W.S. El-Deiry, S.A. Aaronson, and S.W. Lee GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress Molecular Cell 36 2009 379 392
-
(2009)
Molecular Cell
, vol.36
, pp. 379-392
-
-
Ide, T.1
Brown-Endres, L.2
Chu, K.3
Ongusaha, P.P.4
Ohtsuka, T.5
El-Deiry, W.S.6
Aaronson, S.A.7
Lee, S.W.8
-
31
-
-
28544432790
-
The differential effects of mutant p53 alleles on advanced murine lung cancer
-
E.L. Jackson, K.P. Olive, D.A. Tuveson, R. Bronson, D. Crowley, M. Brown, and T. Jacks The differential effects of mutant p53 alleles on advanced murine lung cancer Cancer Research 65 2005 10280 10288
-
(2005)
Cancer Research
, vol.65
, pp. 10280-10288
-
-
Jackson, E.L.1
Olive, K.P.2
Tuveson, D.A.3
Bronson, R.4
Crowley, D.5
Brown, M.6
Jacks, T.7
-
32
-
-
84862124987
-
P53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer
-
J.G. Jackson, V. Pant, Q. Li, L.L. Chang, A. Quintas-Cardama, D. Garza, O. Tavana, P. Yang, T. Manshouri, and Y. Li p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer Cancer Cell 21 2012 793 806
-
(2012)
Cancer Cell
, vol.21
, pp. 793-806
-
-
Jackson, J.G.1
Pant, V.2
Li, Q.3
Chang, L.L.4
Quintas-Cardama, A.5
Garza, D.6
Tavana, O.7
Yang, P.8
Manshouri, T.9
Li, Y.10
-
33
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
S.N. Jones, A.E. Roe, L.A. Donehower, and A. Bradley Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 Nature 378 1995 206 208
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
34
-
-
78649492693
-
Selective activation of p53-mediated tumour suppression in high-grade tumours
-
M.R. Junttila, A.N. Karnezis, D. Garcia, F. Madriles, R.M. Kortlever, F. Rostker, L. Brown Swigart, D.M. Pham, Y. Seo, and G.I. Evan Selective activation of p53-mediated tumour suppression in high-grade tumours Nature 468 2010 567 571
-
(2010)
Nature
, vol.468
, pp. 567-571
-
-
Junttila, M.R.1
Karnezis, A.N.2
Garcia, D.3
Madriles, F.4
Kortlever, R.M.5
Rostker, F.6
Brown Swigart, L.7
Pham, D.M.8
Seo, Y.9
Evan, G.I.10
-
35
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
M. Kaghad, H. Bonnet, A. Yang, L. Creancier, J.C. Biscan, A. Valent, A. Minty, P. Chalon, J.M. Lelias, and X. Dumont Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers Cell 90 1997 809 819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
-
36
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
T. Kamijo, J.D. Weber, G. Zambetti, F. Zindy, M.F. Roussel, and C.J. Sherr Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 Proceedings of the National Academy of Sciences of the United States of America 95 1998 8292 8297
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
37
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
T. Kamijo, F. Zindy, M.F. Roussel, D.E. Quelle, J.R. Downing, R.A. Ashmun, G. Grosveld, and C.J. Sherr Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF Cell 91 1997 649 659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
38
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
M.B. Kastan, O. Onyekwere, D. Sidransky, B. Vogelstein, and R.W. Craig Participation of p53 protein in the cellular response to DNA damage Cancer Research 51 1991 6304 6311
-
(1991)
Cancer Research
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
39
-
-
43049139541
-
P53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
-
K. Kawauchi, K. Araki, K. Tobiume, and N. Tanaka p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation Nature Cell Biology 10 2008 611 618
-
(2008)
Nature Cell Biology
, vol.10
, pp. 611-618
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
40
-
-
0028168643
-
P53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
-
C.J. Kemp, T. Wheldon, and A. Balmain p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis Nature Genetics 8 1994 66 69
-
(1994)
Nature Genetics
, vol.8
, pp. 66-69
-
-
Kemp, C.J.1
Wheldon, T.2
Balmain, A.3
-
41
-
-
39149110563
-
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
-
N. King, M.J. Westbrook, S.L. Young, A. Kuo, M. Abedin, J. Chapman, S. Fairclough, U. Hellsten, Y. Isogai, and I. Letunic The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans Nature 451 2008 783 788
-
(2008)
Nature
, vol.451
, pp. 783-788
-
-
King, N.1
Westbrook, M.J.2
Young, S.L.3
Kuo, A.4
Abedin, M.5
Chapman, J.6
Fairclough, S.7
Hellsten, U.8
Isogai, Y.9
Letunic, I.10
-
42
-
-
0031031049
-
Tumors associated with p53 germline mutations: A synopsis of 91 families
-
P. Kleihues, B. Schauble, A. zur Hausen, J. Esteve, and H. Ohgaki Tumors associated with p53 germline mutations: a synopsis of 91 families The American Journal of Pathology 150 1997 1 13
-
(1997)
The American Journal of Pathology
, vol.150
, pp. 1-13
-
-
Kleihues, P.1
Schauble, B.2
Zur Hausen, A.3
Esteve, J.4
Ohgaki, H.5
-
43
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
H. Kondoh, M.E. Lleonart, J. Gil, J. Wang, P. Degan, G. Peters, D. Martinez, A. Carnero, and D. Beach Glycolytic enzymes can modulate cellular life span Cancer Research 65 2005 177 185
-
(2005)
Cancer Research
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
44
-
-
79955398591
-
Otto Warburg's contributions to current concepts of cancer metabolism
-
W.H. Koppenol, P.L. Bounds, and C.V. Dang Otto Warburg's contributions to current concepts of cancer metabolism Nature Reviews Cancer 11 2011 325 337
-
(2011)
Nature Reviews Cancer
, vol.11
, pp. 325-337
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
45
-
-
65449144050
-
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain
-
J.M. Lambert, P. Gorzov, D.B. Veprintsev, M. Soderqvist, D. Segerback, J. Bergman, A.R. Fersht, P. Hainaut, K.G. Wiman, and V.J. Bykov PRIMA-1 reactivates mutant p53 by covalent binding to the core domain Cancer Cell 15 2009 376 388
-
(2009)
Cancer Cell
, vol.15
, pp. 376-388
-
-
Lambert, J.M.1
Gorzov, P.2
Veprintsev, D.B.3
Soderqvist, M.4
Segerback, D.5
Bergman, J.6
Fersht, A.R.7
Hainaut, P.8
Wiman, K.G.9
Bykov, V.J.10
-
46
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
D.P. Lane Cancer. p53, guardian of the genome Nature 358 1992 15 16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
47
-
-
13644260907
-
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
-
G.A. Lang, T. Iwakuma, Y.A. Suh, G. Liu, V.A. Rao, J.M. Parant, Y.A. Valentin-Vega, T. Terzian, L.C. Caldwell, and L.C. Strong Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome Cell 119 2004 861 872
-
(2004)
Cell
, vol.119
, pp. 861-872
-
-
Lang, G.A.1
Iwakuma, T.2
Suh, Y.A.3
Liu, G.4
Rao, V.A.5
Parant, J.M.6
Valentin-Vega, Y.A.7
Terzian, T.8
Caldwell, L.C.9
Strong, L.C.10
-
48
-
-
70349442548
-
The first 30 years of p53: Growing ever more complex
-
A.J. Levine, and M. Oren The first 30 years of p53: growing ever more complex Nature Reviews Cancer 9 2009 749 758
-
(2009)
Nature Reviews Cancer
, vol.9
, pp. 749-758
-
-
Levine, A.J.1
Oren, M.2
-
49
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
T. Li, N. Kon, L. Jiang, M. Tan, T. Ludwig, Y. Zhao, R. Baer, and W. Gu Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence Cell 149 2012 1269 1283
-
(2012)
Cell
, vol.149
, pp. 1269-1283
-
-
Li, T.1
Kon, N.2
Jiang, L.3
Tan, M.4
Ludwig, T.5
Zhao, Y.6
Baer, R.7
Gu, W.8
-
50
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
T. Lin, C. Chao, S. Saito, S.J. Mazur, M.E. Murphy, E. Appella, and Y. Xu p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression Nature Cell Biology 7 2005 165 171
-
(2005)
Nature Cell Biology
, vol.7
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
Mazur, S.J.4
Murphy, M.E.5
Appella, E.6
Xu, Y.7
-
51
-
-
58049216794
-
P53 regulates hematopoietic stem cell quiescence
-
Y. Liu, S.E. Elf, Y. Miyata, G. Sashida, G. Huang, S. Di Giandomenico, J.M. Lee, A. Deblasio, S. Menendez, and J. Antipin p53 regulates hematopoietic stem cell quiescence Cell Stem Cell 4 2009 37 48
-
(2009)
Cell Stem Cell
, vol.4
, pp. 37-48
-
-
Liu, Y.1
Elf, S.E.2
Miyata, Y.3
Sashida, G.4
Huang, G.5
Di Giandomenico, S.6
Lee, J.M.7
Deblasio, A.8
Menendez, S.9
Antipin, J.10
-
52
-
-
9244224723
-
Intrinsic tumour suppression
-
S.W. Lowe, E. Cepero, and G. Evan Intrinsic tumour suppression Nature 432 2004 307 315
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
57
-
-
77951243028
-
Autophagy regulation by p53
-
M.C. Maiuri, L. Galluzzi, E. Morselli, O. Kepp, S.A. Malik, and G. Kroemer Autophagy regulation by p53 Current Opinion in Cell Biology 22 2010 181 185
-
(2010)
Current Opinion in Cell Biology
, vol.22
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
58
-
-
33646794425
-
Keeping p53 in check: Essential and synergistic functions of Mdm2 and Mdm4
-
J.C. Marine, S. Francoz, M. Maetens, G. Wahl, F. Toledo, and G. Lozano Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4 Cell Death and Differentiation 13 2006 927 934
-
(2006)
Cell Death and Differentiation
, vol.13
, pp. 927-934
-
-
Marine, J.C.1
Francoz, S.2
Maetens, M.3
Wahl, G.4
Toledo, F.5
Lozano, G.6
-
59
-
-
33845611951
-
Modeling the therapeutic efficacy of p53 restoration in tumors
-
C.P. Martins, L. Brown-Swigart, and G.I. Evan Modeling the therapeutic efficacy of p53 restoration in tumors Cell 127 2006 1323 1334
-
(2006)
Cell
, vol.127
, pp. 1323-1334
-
-
Martins, C.P.1
Brown-Swigart, L.2
Evan, G.I.3
-
60
-
-
0030882879
-
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53
-
S.P. Mathupala, C. Heese, and P.L. Pedersen Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53 The Journal of Biological Chemistry 272 1997 22776 22780
-
(1997)
The Journal of Biological Chemistry
, vol.272
, pp. 22776-22780
-
-
Mathupala, S.P.1
Heese, C.2
Pedersen, P.L.3
-
61
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
S. Matoba, J.G. Kang, W.D. Patino, A. Wragg, M. Boehm, O. Gavrilova, P.J. Hurley, F. Bunz, and P.M. Hwang p53 regulates mitochondrial respiration Science 312 2006 1650 1653
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
62
-
-
32244436592
-
P53 suppresses the self-renewal of adult neural stem cells
-
K. Meletis, V. Wirta, S.M. Hede, M. Nister, J. Lundeberg, and J. Frisen p53 suppresses the self-renewal of adult neural stem cells Development 133 2006 363 369
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
63
-
-
0038705141
-
Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53
-
L. Mendoza, E. Orozco, M.A. Rodriguez, G. Garcia-Rivera, T. Sanchez, E. Garcia, and P. Gariglio Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53 Microbiology 149 2003 885 893
-
(2003)
Microbiology
, vol.149
, pp. 885-893
-
-
Mendoza, L.1
Orozco, E.2
Rodriguez, M.A.3
Garcia-Rivera, G.4
Sanchez, T.5
Garcia, E.6
Gariglio, P.7
-
64
-
-
0025111068
-
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
-
D. Michalovitz, O. Halevy, and M. Oren Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell 62 1990 671 680
-
(1990)
Cell
, vol.62
, pp. 671-680
-
-
Michalovitz, D.1
Halevy, O.2
Oren, M.3
-
65
-
-
0033594491
-
P63 is a p53 homologue required for limb and epidermal morphogenesis
-
A.A. Mills, B. Zheng, X.J. Wang, H. Vogel, D.R. Roop, and A. Bradley p63 is a p53 homologue required for limb and epidermal morphogenesis Nature 398 1999 708 713
-
(1999)
Nature
, vol.398
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
66
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
J. Momand, G.P. Zambetti, D.C. Olson, D. George, and A.J. Levine The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation Cell 69 1992 1237 1245
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
67
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
R. Montes de Oca Luna, D.S. Wagner, and G. Lozano Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 Nature 378 1995 203 206
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
68
-
-
72249100428
-
Mutant p53 drives invasion by promoting integrin recycling
-
P.A. Muller, P.T. Caswell, B. Doyle, M.P. Iwanicki, E.H. Tan, S. Karim, N. Lukashchuk, D.A. Gillespie, R.L. Ludwig, and P. Gosselin Mutant p53 drives invasion by promoting integrin recycling Cell 139 2009 1327 1341
-
(2009)
Cell
, vol.139
, pp. 1327-1341
-
-
Muller, P.A.1
Caswell, P.T.2
Doyle, B.3
Iwanicki, M.P.4
Tan, E.H.5
Karim, S.6
Lukashchuk, N.7
Gillespie, D.A.8
Ludwig, R.L.9
Gosselin, P.10
-
70
-
-
56849093474
-
Distinct thresholds govern Myc's biological output in vivo
-
D.J. Murphy, M.R. Junttila, L. Pouyet, A. Karnezis, K. Shchors, D.A. Bui, L. Brown-Swigart, L. Johnson, and G.I. Evan Distinct thresholds govern Myc's biological output in vivo Cancer Cell 14 2008 447 457
-
(2008)
Cancer Cell
, vol.14
, pp. 447-457
-
-
Murphy, D.J.1
Junttila, M.R.2
Pouyet, L.3
Karnezis, A.4
Shchors, K.5
Bui, D.A.6
Brown-Swigart, L.7
Johnson, L.8
Evan, G.I.9
-
71
-
-
0033257077
-
Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system
-
S. Okamura, C.C. Ng, K. Koyama, Y. Takei, H. Arakawa, M. Monden, and Y. Nakamura Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system Oncology Research 11 1999 281 285
-
(1999)
Oncology Research
, vol.11
, pp. 281-285
-
-
Okamura, S.1
Ng, C.C.2
Koyama, K.3
Takei, Y.4
Arakawa, H.5
Monden, M.6
Nakamura, Y.7
-
72
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
J.D. Oliner, K.W. Kinzler, P.S. Meltzer, D.L. George, and B. Vogelstein Amplification of a gene encoding a p53-associated protein in human sarcomas Nature 358 1992 80 83
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
73
-
-
20244385424
-
Drosophila p53 is a structural and functional homolog of the tumor suppressor p53
-
M. Ollmann, L.M. Young, C.J. Di Como, F. Karim, M. Belvin, S. Robertson, K. Whittaker, M. Demsky, W.W. Fisher, and A. Buchman Drosophila p53 is a structural and functional homolog of the tumor suppressor p53 Cell 101 2000 91 101
-
(2000)
Cell
, vol.101
, pp. 91-101
-
-
Ollmann, M.1
Young, L.M.2
Di Como, C.J.3
Karim, F.4
Belvin, M.5
Robertson, S.6
Whittaker, K.7
Demsky, M.8
Fisher, W.W.9
Buchman, A.10
-
75
-
-
24944454988
-
Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
-
Z. Peng Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers Human Gene Therapy 16 2005 1016 1027
-
(2005)
Human Gene Therapy
, vol.16
, pp. 1016-1027
-
-
Peng, Z.1
-
76
-
-
84865181704
-
Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells
-
G. Pontarin, P. Ferraro, L. Bee, P. Reichard, and V. Bianchi Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells Proceedings of the National Academy of Sciences of the United States of America 109 2012 13302 13307
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 13302-13307
-
-
Pontarin, G.1
Ferraro, P.2
Bee, L.3
Reichard, P.4
Bianchi, V.5
-
77
-
-
84862270480
-
P53 dynamics control cell fate
-
J.E. Purvis, K.W. Karhohs, C. Mock, E. Batchelor, A. Loewer, and G. Lahav p53 dynamics control cell fate Science 336 2012 1440 1444
-
(2012)
Science
, vol.336
, pp. 1440-1444
-
-
Purvis, J.E.1
Karhohs, K.W.2
Mock, C.3
Batchelor, E.4
Loewer, A.5
Lahav, G.6
-
79
-
-
33847365838
-
MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis
-
C. Rinaldo, A. Prodosmo, F. Mancini, S. Iacovelli, A. Sacchi, F. Moretti, and S. Soddu MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis Molecular Cell 25 2007 739 750
-
(2007)
Molecular Cell
, vol.25
, pp. 739-750
-
-
Rinaldo, C.1
Prodosmo, A.2
Mancini, F.3
Iacovelli, S.4
Sacchi, A.5
Moretti, F.6
Soddu, S.7
-
80
-
-
33845185824
-
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo
-
I. Ringshausen, C.C. O'Shea, A.J. Finch, L.B. Swigart, and G.I. Evan Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo Cancer Cell 10 2006 501 514
-
(2006)
Cancer Cell
, vol.10
, pp. 501-514
-
-
Ringshausen, I.1
O'Shea, C.C.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
-
81
-
-
0014344270
-
Clinical radiation pathology as applied to curative radiotherapy
-
P. Rubin, and G.W. Casarett Clinical radiation pathology as applied to curative radiotherapy Cancer 22 1968 767 778
-
(1968)
Cancer
, vol.22
, pp. 767-778
-
-
Rubin, P.1
Casarett, G.W.2
-
82
-
-
34247897276
-
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
-
C.J. Sarkisian, B.A. Keister, D.B. Stairs, R.B. Boxer, S.E. Moody, and L.A. Chodosh Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis Nature Cell Biology 9 2007 493 505
-
(2007)
Nature Cell Biology
, vol.9
, pp. 493-505
-
-
Sarkisian, C.J.1
Keister, B.A.2
Stairs, D.B.3
Boxer, R.B.4
Moody, S.E.5
Chodosh, L.A.6
-
83
-
-
0033569423
-
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
-
C.A. Schmitt, M.E. McCurrach, E. de Stanchina, R.R. Wallace-Brodeur, and S.W. Lowe INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53 Genes and Development 13 1999 2670 2677
-
(1999)
Genes and Development
, vol.13
, pp. 2670-2677
-
-
Schmitt, C.A.1
McCurrach, M.E.2
De Stanchina, E.3
Wallace-Brodeur, R.R.4
Lowe, S.W.5
-
84
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
F. Schwartzenberg-Bar-Yoseph, M. Armoni, and E. Karnieli The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression Cancer Research 64 2004 2627 2633
-
(2004)
Cancer Research
, vol.64
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
86
-
-
45849105199
-
Deregulating EMT and senescence: Double impact by a single twist
-
M.A. Smit, and D.S. Peeper Deregulating EMT and senescence: double impact by a single twist Cancer Cell 14 2008 5 7
-
(2008)
Cancer Cell
, vol.14
, pp. 5-7
-
-
Smit, M.A.1
Peeper, D.S.2
-
87
-
-
77952227625
-
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
-
S. Suzuki, T. Tanaka, M.V. Poyurovsky, H. Nagano, T. Mayama, S. Ohkubo, M. Lokshin, H. Hosokawa, T. Nakayama, and Y. Suzuki Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species Proceedings of the National Academy of Sciences of the United States of America 107 2010 7461 7466
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 7461-7466
-
-
Suzuki, S.1
Tanaka, T.2
Poyurovsky, M.V.3
Nagano, H.4
Mayama, T.5
Ohkubo, S.6
Lokshin, M.7
Hosokawa, H.8
Nakayama, T.9
Suzuki, Y.10
-
88
-
-
0034594978
-
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
-
H. Tanaka, H. Arakawa, T. Yamaguchi, K. Shiraishi, S. Fukuda, K. Matsui, Y. Takei, and Y. Nakamura A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage Nature 404 2000 42 49
-
(2000)
Nature
, vol.404
, pp. 42-49
-
-
Tanaka, H.1
Arakawa, H.2
Yamaguchi, T.3
Shiraishi, K.4
Fukuda, S.5
Matsui, K.6
Takei, Y.7
Nakamura, Y.8
-
90
-
-
70449727603
-
Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53
-
T. Van Maerken, L. Ferdinande, J. Taildeman, I. Lambertz, N. Yigit, L. Vercruysse, A. Rihani, M. Michaelis, J. Cinatl Jr., and C.A. Cuvelier Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53 Journal of the National Cancer Institute 101 2009 1562 1574
-
(2009)
Journal of the National Cancer Institute
, vol.101
, pp. 1562-1574
-
-
Van Maerken, T.1
Ferdinande, L.2
Taildeman, J.3
Lambertz, I.4
Yigit, N.5
Vercruysse, L.6
Rihani, A.7
Michaelis, M.8
Cinatl, Jr.J.9
Cuvelier, C.A.10
-
91
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
L.T. Vassilev, B.T. Vu, B. Graves, D. Carvajal, F. Podlaski, Z. Filipovic, N. Kong, U. Kammlott, C. Lukacs, and C. Klein In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 Science 303 2004 844 848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
-
92
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
A. Ventura, D.G. Kirsch, M.E. McLaughlin, D.A. Tuveson, J. Grimm, L. Lintault, J. Newman, E.E. Reczek, R. Weissleder, and T. Jacks Restoration of p53 function leads to tumour regression in vivo Nature 445 2007 661 665
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
94
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
K.H. Vousden, and C. Prives Blinded by the light: the growing complexity of p53 Cell 137 2009 413 431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
96
-
-
84865276622
-
Synthesis of cytochrome c oxidase 2: A p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death
-
C. Wanka, D.P. Brucker, O. Bahr, M. Ronellenfitsch, M. Weller, J.P. Steinbach, and J. Rieger Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death Oncogene 31 2012 3764 3776
-
(2012)
Oncogene
, vol.31
, pp. 3764-3776
-
-
Wanka, C.1
Brucker, D.P.2
Bahr, O.3
Ronellenfitsch, M.4
Weller, M.5
Steinbach, J.P.6
Rieger, J.7
-
97
-
-
12444279265
-
On the origin of cancer cells
-
O. Warburg On the origin of cancer cells Science 123 1956 309 314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
98
-
-
1842536849
-
Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes
-
A. Willis, E.J. Jung, T. Wakefield, and X. Chen Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes Oncogene 23 2004 2330 2338
-
(2004)
Oncogene
, vol.23
, pp. 2330-2338
-
-
Willis, A.1
Jung, E.J.2
Wakefield, T.3
Chen, X.4
-
99
-
-
27744547091
-
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
-
W.S. Wu, S. Heinrichs, D. Xu, S.P. Garrison, G.P. Zambetti, J.M. Adams, and A.T. Look Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma Cell 123 2005 641 653
-
(2005)
Cell
, vol.123
, pp. 641-653
-
-
Wu, W.S.1
Heinrichs, S.2
Xu, D.3
Garrison, S.P.4
Zambetti, G.P.5
Adams, J.M.6
Look, A.T.7
-
100
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
W. Xue, L. Zender, C. Miething, R.A. Dickins, E. Hernando, V. Krizhanovsky, C. Cordon-Cardo, and S.W. Lowe Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas Nature 445 2007 656 660
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
101
-
-
0032161624
-
P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
A. Yang, M. Kaghad, Y. Wang, E. Gillett, M.D. Fleming, V. Dotsch, N.C. Andrews, D. Caput, and F. McKeon p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities Molecular Cell 2 1998 305 316
-
(1998)
Molecular Cell
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dotsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
102
-
-
0033594485
-
P63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
-
A. Yang, R. Schweitzer, D. Sun, M. Kaghad, N. Walker, R.T. Bronson, C. Tabin, A. Sharpe, D. Caput, and C. Crum p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development Nature 398 1999 714 718
-
(1999)
Nature
, vol.398
, pp. 714-718
-
-
Yang, A.1
Schweitzer, R.2
Sun, D.3
Kaghad, M.4
Walker, N.5
Bronson, R.T.6
Tabin, C.7
Sharpe, A.8
Caput, D.9
Crum, C.10
-
103
-
-
17544363909
-
P73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
-
A. Yang, N. Walker, R. Bronson, M. Kaghad, M. Oosterwegel, J. Bonnin, C. Vagner, H. Bonnet, P. Dikkes, and A. Sharpe p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours Nature 404 2000 99 103
-
(2000)
Nature
, vol.404
, pp. 99-103
-
-
Yang, A.1
Walker, N.2
Bronson, R.3
Kaghad, M.4
Oosterwegel, M.5
Bonnin, J.6
Vagner, C.7
Bonnet, H.8
Dikkes, P.9
Sharpe, A.10
-
104
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
-
E. Yonish-Rouach, D. Resnitzky, J. Lotem, L. Sachs, A. Kimchi, and M. Oren Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 Nature 352 1991 345 347
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
105
-
-
0037716990
-
Mitochondrial impairment in p53-deficient human cancer cells
-
S. Zhou, S. Kachhap, and K.K. Singh Mitochondrial impairment in p53-deficient human cancer cells Mutagenesis 18 2003 287 292
-
(2003)
Mutagenesis
, vol.18
, pp. 287-292
-
-
Zhou, S.1
Kachhap, S.2
Singh, K.K.3
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