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Volumn 117, Issue 2, 2001, Pages 333-340

The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis

Author keywords

Bax; Bcl 2 ratio; Cd95; Ceramide; Fas; Melanoma

Indexed keywords

BETULIC ACID; CASPASE; CERAMIDE; CYTOCHROME C; DNA FRAGMENT; FAS ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; SPHINGOSINE DERIVATIVE;

EID: 0035720233     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202x.2001.01409.x     Document Type: Article
Times cited : (478)

References (48)
  • 3
    • 8944230657 scopus 로고    scopus 로고
    • Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice
    • (1996) J Clin Invest , vol.97 , pp. 2651-2659
    • Bargou, R.C.1    Wagener, C.2    Bommert, K.3
  • 11
    • 0030815250 scopus 로고    scopus 로고
    • Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors
    • (1997) Cancer Res , vol.57 , pp. 4956-4964
    • Fulda, S.1    Friesen, C.2    Los, M.3
  • 27
    • 0028883179 scopus 로고
    • Tumor suppressor p 53 is a direct transcriptional activator of the human bax gene
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 31
    • 0028847024 scopus 로고
    • Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis
    • (1995) Nat Med , vol.1 , pp. 1046-1051
    • Pisha, E.1    Chai, H.2    Lee, I.S.3
  • 32
    • 0033832590 scopus 로고    scopus 로고
    • Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2-ratio and loss of spontaneous caspase-3 processing in vivo
    • (2000) Leukemia , vol.14 , pp. 1606-1613
    • Prokop, A.1    Wieder, T.2    Sturm, I.3
  • 34
  • 35
    • 0030162560 scopus 로고    scopus 로고
    • Balancing cell life and death: Bax, apoptosis, and breast cancer
    • (1996) J Clin Invest , vol.97 , pp. 2403-2404
    • Reed, J.C.1
  • 41
    • 0344348993 scopus 로고    scopus 로고
    • Analysis of the p53/BAX pathway in colorectal cancer: Low BAX is a negative prognostic factor in patients with resected liver metastases
    • (1999) J Clin Oncol , vol.17 , pp. 1364-1374
    • Sturm, I.1    Kohne, C.H.2    Wolff, G.3
  • 48


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.