-
1
-
-
1642362408
-
Asbestos and the pleura: a review
-
Cugell,D.W. et al. (2004) Asbestos and the pleura: a review. Chest, 125, 1103-1117.
-
(2004)
Chest
, vol.125
, pp. 1103-1117
-
-
Cugell, D.W.1
-
2
-
-
65349131853
-
Malignant pleural mesothelioma
-
Tsao,A.S. et al. (2009) Malignant pleural mesothelioma. J. Clin. Oncol., 27, 2081-2090.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2081-2090
-
-
Tsao, A.S.1
-
3
-
-
34547100275
-
The resurgence of platinum-based cancer chemotherapy
-
Kelland,L. (2007) The resurgence of platinum-based cancer chemotherapy. Nat. Rev. Cancer, 7, 573-584.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 573-584
-
-
Kelland, L.1
-
4
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
Fulda,S. et al. (2006) Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene, 25, 4798-4811.
-
(2006)
Oncogene
, vol.25
, pp. 4798-4811
-
-
Fulda, S.1
-
5
-
-
42649124337
-
Resistance mechanisms to cancer chemotherapy
-
Redmond,K.M. et al. (2008) Resistance mechanisms to cancer chemotherapy. Front. Biosci., 13, 5138-5154.
-
(2008)
Front. Biosci.
, vol.13
, pp. 5138-5154
-
-
Redmond, K.M.1
-
6
-
-
33745953139
-
BCL-2 in the crosshairs: tipping the balance of life and death
-
Walensky,L.D. (2006) BCL-2 in the crosshairs: tipping the balance of life and death. Cell Death Differ., 13, 1339-1350.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1339-1350
-
-
Walensky, L.D.1
-
7
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle,R.J. et al. (2008) The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol., 9, 47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
-
8
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Yip,K.W. et al. (2008) Bcl-2 family proteins and cancer. Oncogene, 27, 6398-6406.
-
(2008)
Oncogene
, vol.27
, pp. 6398-6406
-
-
Yip, K.W.1
-
9
-
-
1442286330
-
The role of Bcl-2 family members in tumorigenesis
-
Kirkin,V. et al. (2004) The role of Bcl-2 family members in tumorigenesis. Biochim. Biophys. Acta, 1644, 229-249.
-
(2004)
Biochim. Biophys. Acta
, vol.1644
, pp. 229-249
-
-
Kirkin, V.1
-
10
-
-
0032758427
-
Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma
-
Soini,Y. et al. (1999) Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma. Clin. Cancer Res., 5, 3508-3515.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 3508-3515
-
-
Soini, Y.1
-
11
-
-
33745113791
-
Expression of bcl-2 family members in malignant pleural mesothelioma
-
O'Kane,S.L. et al. (2006) Expression of bcl-2 family members in malignant pleural mesothelioma. Acta Oncol., 45, 449-453.
-
(2006)
Acta Oncol.
, vol.45
, pp. 449-453
-
-
O'Kane, S.L.1
-
12
-
-
38549145044
-
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
-
Letai,A.G. (2008) Diagnosing and exploiting cancer's addiction to blocks in apoptosis. Nat. Rev. Cancer, 8, 121-132.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 121-132
-
-
Letai, A.G.1
-
13
-
-
0036621573
-
Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product
-
Smythe,W.R. et al. (2002) Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product. J. Thorac. Cardiovasc. Surg., 123, 1191-1198.
-
(2002)
J. Thorac. Cardiovasc. Surg.
, vol.123
, pp. 1191-1198
-
-
Smythe, W.R.1
-
14
-
-
0037817461
-
Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment
-
Hopkins-Donaldson,S. et al. (2003) Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment. Int. J. Cancer, 106, 160-166.
-
(2003)
Int. J. Cancer
, vol.106
, pp. 160-166
-
-
Hopkins-Donaldson, S.1
-
15
-
-
4444342586
-
Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma
-
Ozvaran,M.K. et al. (2004) Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma. Mol. Cancer Ther., 3, 545-550.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 545-550
-
-
Ozvaran, M.K.1
-
16
-
-
43949111975
-
Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts
-
Littlejohn,J.E. et al. (2008) Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. Int. J. Cancer, 123, 202-208.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 202-208
-
-
Littlejohn, J.E.1
-
17
-
-
33751542949
-
Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
-
Yeow,W.S. et al. (2006) Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Thorac. Cardiovasc. Surg., 132, 1356-1362.
-
(2006)
J. Thorac. Cardiovasc. Surg.
, vol.132
, pp. 1356-1362
-
-
Yeow, W.S.1
-
18
-
-
34247336873
-
Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma
-
Cao,X. et al. (2007) Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma. Cancer Biol. Ther., 6, 246-252.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 246-252
-
-
Cao, X.1
-
19
-
-
22244464818
-
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
-
Willis,S.N. et al. (2005) Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev., 19, 1294-1305.
-
(2005)
Genes Dev.
, vol.19
, pp. 1294-1305
-
-
Willis, S.N.1
-
20
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya,Y. et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J., 19, 5720-5728.
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
-
21
-
-
33745778238
-
Regulation of PUMA-alpha by p53 in cisplatininduced renal cell apoptosis
-
Jiang,M. et al. (2006) Regulation of PUMA-alpha by p53 in cisplatininduced renal cell apoptosis. Oncogene, 25, 4056-4066.
-
(2006)
Oncogene
, vol.25
, pp. 4056-4066
-
-
Jiang, M.1
-
22
-
-
37849052807
-
Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells
-
Zhang,L.J. et al. (2008) Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells. Anticancer Drugs, 19, 159-166.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 159-166
-
-
Zhang, L.J.1
-
23
-
-
58149127992
-
Recent advances in the treatment of malignant pleural mesothelioma
-
Ramalingam,S.S. et al. (2008) Recent advances in the treatment of malignant pleural mesothelioma. J. Thorac. Oncol., 3, 1056-1064.
-
(2008)
J. Thorac. Oncol.
, vol.3
, pp. 1056-1064
-
-
Ramalingam, S.S.1
-
24
-
-
42049116901
-
Malignant mesothelioma resistance to apoptosis: recent discoveries and their implication for effective therapeutic strategies
-
Villanova,F. et al. (2008) Malignant mesothelioma resistance to apoptosis: recent discoveries and their implication for effective therapeutic strategies. Curr. Med. Chem., 15, 631-641.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 631-641
-
-
Villanova, F.1
-
25
-
-
2542443539
-
Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development
-
Fennell,D.A. et al. (2004) Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development. Lancet Oncol., 5, 354-362.
-
(2004)
Lancet Oncol.
, vol.5
, pp. 354-362
-
-
Fennell, D.A.1
-
26
-
-
64949128867
-
Effect of citrate on malignant pleural mesothelioma cells: a synergistic effect with cisplatin
-
Zhang,X. et al. (2009) Effect of citrate on malignant pleural mesothelioma cells: a synergistic effect with cisplatin. Anticancer Res., 29, 1249-1254.
-
(2009)
Anticancer Res.
, vol.29
, pp. 1249-1254
-
-
Zhang, X.1
-
27
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis
-
Leist,M. et al. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med., 185, 1481-1486.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1481-1486
-
-
Leist, M.1
-
28
-
-
1542329621
-
Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)and PKB/AKT-independent fashion
-
Gramaglia,D. et al. (2004) Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)and PKB/AKT-independent fashion. Cell Death Differ., 11, 342-353.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 342-353
-
-
Gramaglia, D.1
-
29
-
-
47949125299
-
Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptor-interacting protein and inhibition of lysosomal cathepsin
-
Sato,T. et al. (2008) Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptor-interacting protein and inhibition of lysosomal cathepsin. J. Immunol., 181, 197-207.
-
(2008)
J. Immunol.
, vol.181
, pp. 197-207
-
-
Sato, T.1
-
30
-
-
0036309455
-
Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma
-
Gordon,G.J. et al. (2002) Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. Carcinogenesis, 23, 1017-1024.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1017-1024
-
-
Gordon, G.J.1
-
31
-
-
0030698810
-
The apoptosis-necrosis paradox Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
-
Hirsch,T. et al. (1997) The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene, 15, 1573-1581.
-
(1997)
Oncogene
, vol.15
, pp. 1573-1581
-
-
Hirsch, T.1
-
32
-
-
34447635894
-
Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells
-
Yang,C. et al. (2007) Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells. Am. J. Physiol. Renal Physiol., 292, F1710-F1717.
-
(2007)
Am. J. Physiol. Renal Physiol.
, vol.292
-
-
Yang, C.1
-
33
-
-
27544446991
-
Life in the balance: how BH3-only proteins induce apoptosis
-
Willis,S.N. et al. (2005) Life in the balance: how BH3-only proteins induce apoptosis. Curr. Opin. Cell Biol., 17, 617-625.
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 617-625
-
-
Willis, S.N.1
-
34
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
Roos,W.P. et al. (2006) DNA damage-induced cell death by apoptosis. Trends Mol. Med., 12, 440-450.
-
(2006)
Trends Mol. Med.
, vol.12
, pp. 440-450
-
-
Roos, W.P.1
-
35
-
-
66449130084
-
Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737
-
Hauck,P. et al. (2009) Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737. Mol. Cancer Ther., 8, 883-892.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 883-892
-
-
Hauck, P.1
-
36
-
-
7644231187
-
Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis
-
Herrant,M. et al. (2004) Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis. Oncogene, 23, 7863-7873.
-
(2004)
Oncogene
, vol.23
, pp. 7863-7873
-
-
Herrant, M.1
-
37
-
-
25144453314
-
Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells
-
Song,L. et al. (2005) Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells. Cancer Biol. Ther., 4, 267-276.
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 267-276
-
-
Song, L.1
-
38
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft,M.F. et al. (2006) The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell, 10, 389-399.
-
(2006)
Cancer Cell
, vol.10
, pp. 389-399
-
-
van Delft, M.F.1
-
39
-
-
33846674886
-
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
-
Chen,S. et al. (2007) Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation. Cancer Res., 67, 782-791.
-
(2007)
Cancer Res.
, vol.67
, pp. 782-791
-
-
Chen, S.1
-
40
-
-
33847061737
-
Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737
-
Tahir,S.K. et al. (2007) Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res., 67, 1176-1183.
-
(2007)
Cancer Res.
, vol.67
, pp. 1176-1183
-
-
Tahir, S.K.1
-
41
-
-
74049125626
-
Bcl-x(L) and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis
-
Brotin,E. et al. (2010) Bcl-x(L) and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis. Int J Cancer, 126(4), 885-895.
-
(2010)
Int J Cancer
, vol.126
, Issue.4
, pp. 885-895
-
-
Brotin, E.1
-
42
-
-
38949123709
-
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer
-
Mohammad,R. et al. (2008) Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer. Recent Pat. Anticancer Drug Discov., 3, 20-30.
-
(2008)
Recent Pat. Anticancer Drug Discov.
, vol.3
, pp. 20-30
-
-
Mohammad, R.1
-
43
-
-
67649386118
-
Concepts in in vivo siRNA delivery for cancer therapy
-
Gondi,C.S. et al. (2009) Concepts in in vivo siRNA delivery for cancer therapy. J. Cell. Physiol., 220, 285-291.
-
(2009)
J. Cell. Physiol.
, vol.220
, pp. 285-291
-
-
Gondi, C.S.1
-
44
-
-
65749110883
-
Small silencing RNAs: state-of-the-art
-
Grimm,D. (2009) Small silencing RNAs: state-of-the-art. Adv. Drug Deliv. Rev., 61, 672-703.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 672-703
-
-
Grimm, D.1
|