Apoptosis signal regulating kinase 1 (ASK1): Potential as a therapeutic target for Alzheimer's disease

International Journal of Molecular Sciences

Volumn 15, Issue 2, 2014, Pages 2119-2129

  Song, Juhyun ^a   Park, Kyung Ah ^a   Lee, Won Taek ^a   Lee, Jong Eun ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

A Neurotoxicity; Alzheimer's disease (AD); Apoptosis signal regulating kinase 1 (ASK1); Endoplasmic reticulum (ER) stress; Insulin signal transduction; Oxidative stress; Tau protein phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN; APOPTOSIS SIGNAL REGULATING KINASE 1; INSULIN; INSULIN RECEPTOR SUBSTRATE; MITOGEN ACTIVATED PROTEIN KINASE; PRESENILIN 1; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TAU PROTEIN; TUMOR NECROSIS FACTOR ALPHA; MAP3K5 PROTEIN, HUMAN;

ALZHEIMER DISEASE; COGNITIVE DEFECT; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; HUMAN; NERVE CELL NECROSIS; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; REVIEW; SENILE PLAQUE; SIGNAL TRANSDUCTION; ANIMAL; METABOLISM;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ENDOPLASMIC RETICULUM STRESS; HUMANS; INSULIN; MAP KINASE KINASE KINASE 5; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84893161647     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15022119     Document Type: Review

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