메뉴 건너뛰기




Volumn 66, Issue , 2012, Pages 39-63

Yeast ATP-binding cassette transporters conferring multidrug resistance

Author keywords

Cdr1p; nucleotide binding domain; Pdr5p; pleiotropic drug resistance; transmembrane domain

Indexed keywords

ABC TRANSPORTER; FUNGAL PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PHOSPHOLIPID; STEROL;

EID: 84858704434     PISSN: 00664227     EISSN: 15453251     Source Type: Book Series    
DOI: 10.1146/annurev-micro-092611-150111     Document Type: Article
Times cited : (188)

References (111)
  • 1
    • 63449139456 scopus 로고    scopus 로고
    • Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
    • Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, et al. 2009. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 323:1718-22
    • (2009) Science , vol.323 , pp. 1718-1722
    • Aller, S.G.1    Yu, J.2    Ward, A.3    Weng, Y.4    Chittaboina, S.5
  • 2
    • 0030716391 scopus 로고    scopus 로고
    • The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter
    • Balan I, Alarco AM, Raymond M. 1997. The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter. J. Bacteriol. 179:7210-18
    • (1997) J. Bacteriol , vol.179 , pp. 7210-7218
    • Balan, I.1    Alarco, A.M.2    Raymond, M.3
  • 4
    • 0028932101 scopus 로고
    • Yeast multidrug resistance: The PDR network
    • Balzi E, Goffeau A. 1995. Yeast multidrug resistance: the PDR network. J. Bioenerg. Biomembr. 27:71-76
    • (1995) J. Bioenerg. Biomembr , vol.27 , pp. 71-76
    • Balzi, E.1    Goffeau, A.2
  • 5
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi E, Wang M, Leterme S, Van Dyck L, Goffeau A. 1994. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J. Biol. Chem. 269:2206-14
    • (1994) J. Biol. Chem , vol.269 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 6
    • 0028111508 scopus 로고
    • Molecular cloning and expression of Saccharomyces cerevisiae STS1 gene product, a yeast ABC transporter conferring mycotoxin resistance
    • Bissinger PH, Kuchler K. 1994. Molecular cloning and expression of Saccharomyces cerevisiae STS1 gene product, a yeast ABC transporter conferring mycotoxin resistance. J. Biol. Chem. 269:4180-86
    • (1994) J. Biol. Chem , vol.269 , pp. 4180-4186
    • Bissinger, P.H.1    Kuchler, K.2
  • 7
    • 84857635727 scopus 로고
    • The mammalian ABC transporter ABCA1 induces lipid-dependent drug sensitivity in yeast
    • Bocer T, Zarubica A, Roussel A, Flis K, Trombik T, et al. 2012. The mammalian ABC transporter ABCA1 induces lipid-dependent drug sensitivity in yeast. Biochim. Biophys. Acta 1821:373-80
    • (1821) Biochim. Biophys. Acta , pp. 373-380
    • Bocer, T.1    Zarubica, A.2    Roussel, A.3    Flis, K.4    Trombik, T.5
  • 9
    • 0025726687 scopus 로고
    • Physical, transcriptional and genetical mapping of a 24 kb DNA fragment located between the PMA1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae
    • Capieaux E, Ulaszewski S, Balzi E, Goffeau A. 1991. Physical, transcriptional and genetical mapping of a 24 kb DNA fragment located between the PMA1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae. Yeast 7:275-80
    • (1991) Yeast , vol.7 , pp. 275-280
    • Capieaux, E.1    Ulaszewski, S.2    Balzi, E.3    Goffeau, A.4
  • 10
    • 0030671457 scopus 로고    scopus 로고
    • Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes
    • Carvajal E, Van Den Hazel HB, Cybularz-Kolaczkowska A, Balzi E, Goffeau A. 1997. Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes. Mol. Gen. Genet. 256:406-15
    • (1997) Mol. Gen. Genet , vol.256 , pp. 406-415
    • Carvajal, E.1    Van Den Hazel, H.B.2    Cybularz-Kolaczkowska, A.3    Balzi, E.4    Goffeau, A.5
  • 11
    • 0035724486 scopus 로고    scopus 로고
    • Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains
    • Daumke O, Knittler MR. 2001. Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains. Eur. J. Biochem. 268:4776-86
    • (2001) Eur. J. Biochem , vol.268 , pp. 4776-4786
    • Daumke, O.1    Knittler, M.R.2
  • 12
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M, Andrey R, Rando A. 2001. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 11:1156-66
    • (2001) Genome Res , vol.11 , pp. 1156-1166
    • Dean, M.1    Andrey, R.2    Rando, A.3
  • 13
    • 0031056684 scopus 로고    scopus 로고
    • Complete inventory of the yeast ABC proteins
    • Decottignies A, Goffeau A. 1997. Complete inventory of the yeast ABC proteins. Nat. Genet. 15:137-45
    • (1997) Nat. Genet , vol.15 , pp. 137-145
    • Decottignies, A.1    Goffeau, A.2
  • 15
    • 0028352302 scopus 로고
    • Solubilisation and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast
    • Decottignies A, Kolaczkowski M, Balzi E, Goffeau A. 1994. Solubilisation and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast. J. Biol. Chem. 269:12797-803
    • (1994) J. Biol. Chem , vol.269 , pp. 12797-12803
    • Decottignies, A.1    Kolaczkowski, M.2    Balzi, E.3    Goffeau, A.4
  • 16
    • 0029073576 scopus 로고
    • Identification and characterisation of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane
    • Decottignies A, Lambert L, Catty P, Degand H, Eppings EA, et al. 1995. Identification and characterisation of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane. J. Biol. Chem. 270:18150-57
    • (1995) J. Biol. Chem , vol.270 , pp. 18150-18157
    • Decottignies, A.1    Lambert, L.2    Catty, P.3    Degand, H.4    Eppings, E.A.5
  • 17
    • 0027998450 scopus 로고
    • PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon
    • Delaveau T, Delahodde A, Carvajal E, Subik J, Jacq C. 1994. PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon. Mol. Gen. Genet. 244:501-11
    • (1994) Mol. Gen. Genet , vol.244 , pp. 501-511
    • Delaveau, T.1    Delahodde, A.2    Carvajal, E.3    Subik, J.4    Jacq, C.5
  • 18
    • 0029994749 scopus 로고    scopus 로고
    • Role of translocases in the generation of phosphatidylserine asymmetry
    • Diaz C, Schroit AJ. 1996. Role of translocases in the generation of phosphatidylserine asymmetry. J. Membr. Biol. 151:1-9
    • (1996) J. Membr. Biol , vol.151 , pp. 1-9
    • Diaz, C.1    Schroit, A.J.2
  • 19
    • 0034669176 scopus 로고    scopus 로고
    • Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis
    • Diederichs K, Diez J, Greller G, Muller C, Breed J, et al. 2000. Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J. 19:5951-61
    • (2000) EMBO J , vol.19 , pp. 5951-5961
    • Diederichs, K.1    Diez, J.2    Greller, G.3    Muller, C.4    Breed, J.5
  • 20
    • 0033616421 scopus 로고    scopus 로고
    • Asymmetric distribution of phosphatidylethanolamine in C. albicans: Possiblemediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily
    • Dogra S, Krishnamurthy S, Gupta V, Dixit BL, Gupta CM, et al. 1999. Asymmetric distribution of phosphatidylethanolamine in C. albicans: possiblemediation by CDR1, a multidrug transporter belonging to ATP binding cassette (ABC) superfamily. Yeast 15:111-21
    • (1999) Yeast , vol.15 , pp. 111-121
    • Dogra, S.1    Krishnamurthy, S.2    Gupta, V.3    Dixit, B.L.4    Gupta, C.M.5
  • 21
    • 0034063860 scopus 로고    scopus 로고
    • The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines the substrate specificity and inhibitor susceptibility
    • Egner R, Bauer BE, Kuchler K. 2000. The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines the substrate specificity and inhibitor susceptibility. Mol. Microbiol. 35:1255-63
    • (2000) Mol. Microbiol , vol.35 , pp. 1255-1263
    • Egner, R.1    Bauer, B.E.2    Kuchler, K.3
  • 22
    • 0028783747 scopus 로고
    • Endocytosis and vacuolar degradation of the plasma membrane localized Pdr5 ATP binding cassette multidrug transporter in Saccharomyces cerevisiae
    • Egner R, Mahe Y, Pandjaitan R, Kuchler K. 1995. Endocytosis and vacuolar degradation of the plasma membrane localized Pdr5 ATP binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:5879-87
    • (1995) Mol. Cell. Biol , vol.15 , pp. 5879-5887
    • Egner, R.1    Mahe, Y.2    Pandjaitan, R.3    Kuchler, K.4
  • 23
    • 77955175082 scopus 로고    scopus 로고
    • Asymmetrically inheritedmultidrug resistance transporters are recessive determinants in cellular replicative ageing
    • Eldakak A, RancatiG, Rubinstein B, Paul P, ConawayV, Li R. 2010. Asymmetrically inheritedmultidrug resistance transporters are recessive determinants in cellular replicative ageing. Nat. Cell Biol. 12:799-805
    • (2010) Nat. Cell Biol , vol.12 , pp. 799-805
    • Eldakak, A.1    Rancatig Rubinstein, B.2    Paul, P.3    Conawayv Li, R.4
  • 25
    • 64349101278 scopus 로고    scopus 로고
    • Topological polar surface area defines substrate transport by multidrug resistance associated protein 1 (MRP1/ABCC1)
    • Fernandes J, Gattass CR. 2009. Topological polar surface area defines substrate transport by multidrug resistance associated protein 1 (MRP1/ABCC1). J. Med. Chem. 52:1214-18
    • (2009) J. Med. Chem , vol.52 , pp. 1214-1218
    • Fernandes, J.1    Gattass, C.R.2
  • 26
    • 0038485609 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p
    • Ferreira-Pereira A, Marco S, Decottignies A, Nader J, Goffeau A, Rigaud JL. 2003. Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p. J. Biol. Chem. 278:11995-99
    • (2003) J. Biol. Chem , vol.278 , pp. 11995-11999
    • Ferreira-Pereira, A.1    Marco, S.2    Decottignies, A.3    Nader, J.4    Goffeau, A.5    Rigaud, J.L.6
  • 27
    • 0032487393 scopus 로고    scopus 로고
    • A fourth gene from the Candida albicans CDR family of ABC transporters
    • Franz R, Michel S, Morschhauser J. 1998. A fourth gene from the Candida albicans CDR family of ABC transporters. Gene 220:91-98
    • (1998) Gene , vol.220 , pp. 91-98
    • Franz, R.1    Michel, S.2    Morschhauser, J.3
  • 28
    • 0033616630 scopus 로고    scopus 로고
    • Evidence for altered ion transport in Saccharomyces cerevisiae overexpressing human MDR1 protein
    • Fritz F, Howard EM, HoffmanMM, Roepe PD. 1999. Evidence for altered ion transport in Saccharomyces cerevisiae overexpressing human MDR1 protein. Biochemistry 38:4214-26
    • (1999) Biochemistry , vol.38 , pp. 4214-4226
    • Fritz, F.1    Howard, E.M.2    Hoffman, M.M.3    Roepe, P.D.4
  • 29
    • 33645307384 scopus 로고    scopus 로고
    • The ABC protein turned chloride channel whose failure causes cystic fibrosis
    • Gadsby DC, Vergani P, Csanady L. 2006. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 440:477-83
    • (2006) Nature , vol.440 , pp. 477-483
    • Gadsby, D.C.1    Vergani, P.2    Csanady, L.3
  • 30
    • 27544514993 scopus 로고    scopus 로고
    • Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans
    • Gaur M, Choudhury D, Prasad R. 2005. Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans. J. Mol. Microbiol. Biotechnol. 9:3-15
    • (2005) J. Mol. Microbiol. Biotechnol , vol.9 , pp. 3-15
    • Gaur, M.1    Choudhury, D.2    Prasad, R.3
  • 31
    • 0037458550 scopus 로고    scopus 로고
    • Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux
    • Golin J, Ambudkar SV, Gottesman MM, Habib AD, Sczepanski J, et al. 2003. Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux. J. Biol. Chem. 278:5963-69
    • (2003) J. Biol. Chem , vol.278 , pp. 5963-5969
    • Golin, J.1    Ambudkar, S.V.2    Gottesman, M.M.3    Habib, A.D.4    Sczepanski, J.5
  • 32
    • 22244472651 scopus 로고    scopus 로고
    • The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5p, a major yeast drug transporter
    • Hanson L, May L, Tuma P, Keeven J, Mehl P, et al. 2005. The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5p, a major yeast drug transporter. Biochemistry 44:9703-13
    • (2005) Biochemistry , vol.44 , pp. 9703-9713
    • Hanson, L.1    May, L.2    Tuma, P.3    Keeven, J.4    Mehl, P.5
  • 33
    • 0035019469 scopus 로고    scopus 로고
    • ABC transporters: Physiology, structure andmechanism-an overview
    • Higgins CF. 2001. ABC transporters: physiology, structure andmechanism-an overview. Res. Microbiol. 152:205-10
    • (2001) Res. Microbiol , vol.152 , pp. 205-210
    • Higgins, C.F.1
  • 34
    • 0028041072 scopus 로고
    • Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance
    • Hirata D, Yano K, Miyahara K, Miyakawa T. 1994. Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance. Curr. Genet. 26:285-94
    • (1994) Curr. Genet , vol.26 , pp. 285-294
    • Hirata, D.1    Yano, K.2    Miyahara, K.3    Miyakawa, T.4
  • 35
    • 63149175755 scopus 로고    scopus 로고
    • Putative role for ABC multidrug exporters in yeast quorum sensing
    • Hlavacek O, Kucerova H, Harant K, Palkova Z, Vachova L. 2009. Putative role for ABC multidrug exporters in yeast quorum sensing. FEBS Lett. 583:1107-13
    • (2009) FEBS Lett , vol.583 , pp. 1107-1113
    • Hlavacek, O.1    Kucerova, H.2    Harant, K.3    Palkova, Z.4    Vachova, L.5
  • 36
    • 0033866297 scopus 로고    scopus 로고
    • 2+-calmodulin-dependent protein kinase in yeasts results in constitutive weak organic acid resistance, associated with a post-transcriptional activation of the Pdr12 ATP-binding cassette transporter
    • 2+-calmodulin-dependent protein kinase in yeasts results in constitutive weak organic acid resistance, associated with a post-transcriptional activation of the Pdr12 ATP-binding cassette transporter. Mol. Microbiol. 37:595-605
    • (2000) Mol. Microbiol , vol.37 , pp. 595-605
    • Holyoak, C.D.1    Thompson, S.2    Calderon, C.O.3    Hatzixanthis, K.4    Bauer, B.5
  • 37
    • 0034705293 scopus 로고    scopus 로고
    • Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
    • Hopfner KP, Karcher A, Shin DS, Craig L, Arthur LM, et al. 2000. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell 101:789-800
    • (2000) Cell , vol.101 , pp. 789-800
    • Hopfner, K.P.1    Karcher, A.2    Shin, D.S.3    Craig, L.4    Arthur, L.M.5
  • 38
  • 39
    • 4744371579 scopus 로고    scopus 로고
    • ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry
    • Jha S, Dabas N, Karnani N, Saini P, Prasad R. 2004. ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry. FEMS Yeast Res. 5:63-72
    • (2004) FEMS Yeast Res , vol.5 , pp. 63-72
    • Jha, S.1    Dabas, N.2    Karnani, N.3    Saini, P.4    Prasad, R.5
  • 40
    • 0042318833 scopus 로고    scopus 로고
    • Purification and characterization of N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: Uncommon cysteine 193 of Walker A is critical for ATP hydrolysis
    • Jha S, Karnani N, Dhar SK, Mukhopadhyay K, Shukla S, et al. 2003. Purification and characterization of N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Biochemistry 42:10822-32
    • (2003) Biochemistry , vol.42 , pp. 10822-10832
    • Jha, S.1    Karnani, N.2    Dhar, S.K.3    Mukhopadhyay, K.4    Shukla, S.5
  • 41
    • 0033958086 scopus 로고    scopus 로고
    • Multiple physiological functions for multidrug transporter P-glycoprotein
    • Johnstone RW, Ruefli AA, Smyth MJ. 2000. Multiple physiological functions for multidrug transporter P-glycoprotein. Trends Biochem. Sci. 25:1-6
    • (2000) Trends Biochem. Sci , vol.25 , pp. 1-6
    • Johnstone, R.W.1    Ruefli, A.A.2    Smyth, M.J.3
  • 42
    • 34547943910 scopus 로고    scopus 로고
    • Nucleotide-dependent allostery within the ABC transporter ATP-binding cassette: A computational study of the MJ0796 dimer
    • Jones PM, George AM. 2007. Nucleotide-dependent allostery within the ABC transporter ATP-binding cassette: a computational study of the MJ0796 dimer. J. Biol. Chem. 282:22793-803
    • (2007) J. Biol. Chem , vol.282 , pp. 22793-22803
    • Jones, P.M.1    George, A.M.2
  • 44
    • 0029836129 scopus 로고    scopus 로고
    • Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATPbinding cassette transporter protein-encoding gene PDR5
    • Katzmann DJ, Hallstrom TC, Mahe Y, Moye-Rowley WS. 1996. Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATPbinding cassette transporter protein-encoding gene PDR5. J. Biol. Chem. 271:23049-54
    • (1996) J. Biol. Chem , vol.271 , pp. 23049-23054
    • Katzmann, D.J.1    Hallstrom, T.C.2    Mahe, Y.3    Moye-Rowley, W.S.4
  • 45
    • 78650886911 scopus 로고    scopus 로고
    • The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study
    • Kohut P, Wustner D, Hronska L, Kuchler K, Hapala I, Valachovic M. 2011. The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: dehydroergosterol fluorescence study. Biochem. Biophys. Res. Commun. 404:233-38
    • (2011) Biochem. Biophys. Res. Commun , vol.404 , pp. 233-238
    • Kohut, P.1    Wustner, D.2    Hronska, L.3    Kuchler, K.4    Hapala, I.5    Valachovic, M.6
  • 46
    • 0033495495 scopus 로고    scopus 로고
    • Regulation of pleiotropic drug resistance in yeast
    • Kolaczkowska A, Goffeau A. 1999. Regulation of pleiotropic drug resistance in yeast. Drug Resist. Updates 2:403-14
    • (1999) Drug Resist. Updates , vol.2 , pp. 403-414
    • Kolaczkowska, A.1    Goffeau, A.2
  • 47
    • 0031796062 scopus 로고    scopus 로고
    • In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network
    • Kolaczkowski M, Kolaczkowska A, Luczynski J, Witek S, Goffeau A. 1998. In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network. Microbial Drug Resist. 4:143-58
    • (1998) Microbial Drug Resist , vol.4 , pp. 143-158
    • Kolaczkowski, M.1    Kolaczkowska, A.2    Luczynski, J.3    Witek, S.4    Goffeau, A.5
  • 49
    • 77951887229 scopus 로고    scopus 로고
    • Phylogenetic analysis of fungalABCtransporters
    • Kovalchuk A, Driessen AJ. 2010. Phylogenetic analysis of fungalABCtransporters. BMCGenomics 11:177
    • (2010) BMCGenomics , vol.11 , pp. 177
    • Kovalchuk, A.1    Driessen, A.J.2
  • 50
    • 0032580522 scopus 로고    scopus 로고
    • Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: Expression of a yeast multidrug transporter in baculovirus expression system
    • Krishnamurthy S, Chatterjee U, Gupta V, Prasad R, Das P, et al. 1998. Deletion of transmembrane domain 12 of CDR1, a multidrug transporter from Candida albicans, leads to altered drug specificity: expression of a yeast multidrug transporter in baculovirus expression system. Yeast 14:535-50
    • (1998) Yeast , vol.14 , pp. 535-550
    • Krishnamurthy, S.1    Chatterjee, U.2    Gupta, V.3    Prasad, R.4    Das, P.5
  • 51
    • 0032521514 scopus 로고    scopus 로고
    • Expression of CDR1, a multidrug resistance gene of Candida albicans: In vitro transcriptional activation by heat shock, drugs and human steroid hormones
    • Krishnamurthy S, Gupta V, Prasad R, Panwar SL, Prasad R. 1998. Expression of CDR1, a multidrug resistance gene of Candida albicans: in vitro transcriptional activation by heat shock, drugs and human steroid hormones. FEMS Microbiol. Lett. 160:191-97
    • (1998) FEMS Microbiol. Lett , vol.160 , pp. 191-197
    • Krishnamurthy, S.1    Gupta, V.2    Prasad, R.3    Panwar, S.L.4    Prasad, R.5
  • 52
    • 0031909801 scopus 로고    scopus 로고
    • Characterisation of human steroid hormone transport mediated by Cdr1p, multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family
    • Krishnamurthy S, Gupta V, Snehlata P, Prasad R. 1998. Characterisation of human steroid hormone transport mediated by Cdr1p, multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family. FEMS Microbiol. Lett. 158:69-74
    • (1998) FEMS Microbiol. Lett , vol.158 , pp. 69-74
    • Krishnamurthy, S.1    Gupta, V.2    Snehlata, P.3    Prasad, R.4
  • 53
    • 77954659343 scopus 로고    scopus 로고
    • Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable
    • Kumar A, Shukla S, Mandal A, Shukla S, Ambudkar SV, Prasad R. 2010. Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable. Biochim. Biophys. Acta 1798:1757-66
    • (2010) Biochim. Biophys. Acta , vol.1798 , pp. 1757-1766
    • Kumar, A.1    Shukla, S.2    Mandal, A.3    Shukla, S.4    Ambudkar, S.V.5    Prasad, R.6
  • 55
    • 34447579240 scopus 로고    scopus 로고
    • Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae
    • Lamping E, Monk BC, Niimi K, Holmes AR, Tsao S, et al. 2007. Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot. Cell 6:1150-65
    • (2007) Eukaryot. Cell , vol.6 , pp. 1150-1165
    • Lamping, E.1    Monk, B.C.2    Niimi, K.3    Holmes, A.R.4    Tsao, S.5
  • 56
    • 0036207991 scopus 로고    scopus 로고
    • New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system
    • Le Crom S, Devaux PF, Marc P, Zhang X, Moye-Rowley WS, Jacq C. 2002. New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol. Cell. Biol. 22:2642-49
    • (2002) Mol. Cell. Biol , vol.22 , pp. 2642-2649
    • Le Crom, S.1    Devaux, P.F.2    Marc, P.3    Zhang, X.4    Moye-Rowley, W.S.5    Jacq, C.6
  • 57
    • 0025237430 scopus 로고
    • Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces
    • Leppert G, McDevitt R, Falco SC, Van DykTK, FickeMB, Golin J. 1990. Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces. Genetics 125:13-20
    • (1990) Genetics , vol.125 , pp. 13-20
    • Leppert, G.1    McDevitt, R.2    Falco, S.C.3    Van Dyk, T.K.4    Ficke, M.B.5    Golin, J.6
  • 58
    • 0037449746 scopus 로고    scopus 로고
    • Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains
    • Loo TW, Bartlett MC, Clarke DM. 2003. Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains. J. Biol. Chem. 278:1575-78
    • (2003) J. Biol. Chem , vol.278 , pp. 1575-1578
    • Loo, T.W.1    Bartlett, M.C.2    Clarke, D.M.3
  • 59
    • 33749236250 scopus 로고    scopus 로고
    • A fungal family of transcriptional regulators: The zinc cluster proteins
    • MacPherson S, Larochelle M, Turcotte B. 2006. A fungal family of transcriptional regulators: the zinc cluster proteins. Microbiol. Mol. Biol. Rev. 70:583-604
    • (2006) Microbiol. Mol. Biol. Rev , vol.70 , pp. 583-604
    • MacPherson, S.1    Larochelle, M.2    Turcotte, B.3
  • 60
    • 0029815138 scopus 로고    scopus 로고
    • The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo
    • Mahe Y, Lemoine Y, Kuchler K. 1996. The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo. J. Biol. Chem. 271:26167-72
    • (1996) J. Biol. Chem , vol.271 , pp. 26167-26172
    • Mahe, Y.1    Lemoine, Y.2    Kuchler, K.3
  • 62
    • 0035165769 scopus 로고    scopus 로고
    • Unusual susceptibility of a multidrug-resistance yeast strain to peptidic antifungals
    • Milewski S, Mignini F, Prasad R, Borowski E. 2001. Unusual susceptibility of a multidrug-resistance yeast strain to peptidic antifungals. Antimicrob. Agents Chemother. 45:223-28
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 223-228
    • Milewski, S.1    Mignini, F.2    Prasad, R.3    Borowski, E.4
  • 64
    • 73749084037 scopus 로고    scopus 로고
    • Regulation ofmultidrug resistance in pathogenic fungi
    • Morschhauser J. 2010. Regulation ofmultidrug resistance in pathogenic fungi. Fungal Genet. Biol. 47:94-106
    • (2010) Fungal Genet. Biol , vol.47 , pp. 94-106
    • Morschhauser, J.1
  • 65
    • 80053267267 scopus 로고    scopus 로고
    • Genome-wide association analysis of clinical versus nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis
    • Muller LA, Lucas JE, Georgianna DR, McCusker JH. 2011. Genome-wide association analysis of clinical versus nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis. Mol. Ecol. 20:4085-97
    • (2011) Mol. Ecol , vol.20 , pp. 4085-4097
    • Muller, L.A.1    Lucas, J.E.2    Georgianna, D.R.3    McCusker, J.H.4
  • 66
    • 0035185602 scopus 로고    scopus 로고
    • Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters
    • Nakamura K, Niimi M, Niimi K, Holmes AR, Yates JE, et al. 2001. Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters. Antimicrob. Agents Chemother. 45:3366-74
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 3366-3374
    • Nakamura, K.1    Niimi, M.2    Niimi, K.3    Holmes, A.R.4    Yates, J.E.5
  • 67
    • 38649112299 scopus 로고    scopus 로고
    • Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: Both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts
    • Pasrija R, Panwar SL, Prasad R. 2008. Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts. Antimicrob. Agents Chemother. 52:694-704
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 694-704
    • Pasrija, R.1    Panwar, S.L.2    Prasad, R.3
  • 68
    • 71449097048 scopus 로고    scopus 로고
    • ABC transporters in Saccharomyces cerevisiae and their interactors: New technology advances the biology of the ABCC (MRP) subfamily
    • Paumi CM, Chuk M, Snider J, Stagljar I, Michaelis S. 2009. ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily. Microbiol. Mol. Biol. Rev. 73:577-93
    • (2009) Microbiol. Mol. Biol. Rev , vol.73 , pp. 577-593
    • Paumi, C.M.1    Chuk, M.2    Snider, J.3    Stagljar, I.4    Michaelis, S.5
  • 69
    • 0037171818 scopus 로고    scopus 로고
    • A computational ensemble pharmacophore model for identifying substrates of P-glycoprotein
    • Penzotti JE, LambML, Evensen E, Grootenhuis PD. 2002. A computational ensemble pharmacophore model for identifying substrates of P-glycoprotein. J. Med. Chem. 45:1737-40
    • (2002) J. Med. Chem , vol.45 , pp. 1737-1740
    • Penzotti, J.E.1    Lamb, M.L.2    Evensen, E.3    Grootenhuis, P.D.4
  • 70
    • 33747734734 scopus 로고    scopus 로고
    • ER-associated degradation of membrane proteins in yeast
    • Pety de Thoźee C, Ghislain M. 2006. ER-associated degradation of membrane proteins in yeast. Sci. World J. 6:967-83
    • (2006) Sci. World J , vol.6 , pp. 967-983
    • Pety De Thoźee, C.1    Ghislain, M.2
  • 71
    • 0032479995 scopus 로고    scopus 로고
    • The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast
    • Piper P, Mahe Y, Thompson S, Pandjaitan R, Holyoak C, et al. 1998. The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast. EMBO J. 17:4257-65
    • (1998) EMBO J , vol.17 , pp. 4257-4265
    • Piper, P.1    Mahe, Y.2    Thompson, S.3    Pandjaitan, R.4    Holyoak, C.5
  • 72
    • 0032484024 scopus 로고    scopus 로고
    • Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome
    • Plemper RK, Egner R, Kuchler K, Wolf DH. 1998. Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome. J. Biol. Chem. 273:32848-56
    • (1998) J. Biol. Chem , vol.273 , pp. 32848-32856
    • Plemper, R.K.1    Egner, R.2    Kuchler, K.3    Wolf, D.H.4
  • 73
    • 84869109254 scopus 로고    scopus 로고
    • Functionally relevant residues of Cdr1p: A multidrug ABC transporter of human pathogenic Candida albicans
    • Prasad R, Sharma M, Rawal MK. 2011. Functionally relevant residues of Cdr1p: a multidrug ABC transporter of human pathogenic Candida albicans. J. Amino Acids 2011:531412
    • (2011) J. Amino Acids , vol.2011 , pp. 531412
    • Prasad, R.1    Sharma, M.2    Rawal, M.K.3
  • 74
    • 0035985631 scopus 로고    scopus 로고
    • Drug resistance in yeasts-an emerging scenario
    • Prasad R, Snehlata P, Smriti. 2002. Drug resistance in yeasts-an emerging scenario. Adv. Microb. Physiol. 46:155-201
    • (2002) Adv. Microb. Physiol , vol.46 , pp. 155-201
    • Prasad, R.1    Smriti, S.P.2
  • 75
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of C. albicans, CDR1, conferring multiple resistance to drugs and antifungals
    • Prasad R, Worgifosse PD, Goffeau A, Balzi E. 1995. Molecular cloning and characterization of a novel gene of C. albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr. Genet. 27:320-29
    • (1995) Curr. Genet , vol.27 , pp. 320-329
    • Prasad, R.1    Worgifosse, P.D.2    Goffeau, A.3    Balzi, E.4
  • 76
    • 68749120814 scopus 로고    scopus 로고
    • The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport
    • Puri N, Gaur M, Sharma M, Shukla S, Ambudkar SV, Prasad R. 2009. The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport. Biochim. Biophys. Acta 1788:1752-61
    • (2009) Biochim. Biophys. Acta , vol.1788 , pp. 1752-1761
    • Puri, N.1    Gaur, M.2    Sharma, M.3    Shukla, S.4    Ambudkar, S.V.5    Prasad, R.6
  • 77
    • 78650852825 scopus 로고    scopus 로고
    • Overcoming the heterologous bias: An in vivo functional analysis of multidrug efflux transporter, CgCdr1p in matched pair clinical isolates of Candida glabrata
    • Puri N, Manoharlal R, Sharma M, Sanglard D, Prasad R. 2011. Overcoming the heterologous bias: an in vivo functional analysis of multidrug efflux transporter, CgCdr1p in matched pair clinical isolates of Candida glabrata. Biochem. Biophys. Res. Commun. 404:357-63
    • (2011) Biochem. Biophys. Res. Commun , vol.404 , pp. 357-363
    • Puri, N.1    Manoharlal, R.2    Sharma, M.3    Sanglard, D.4    Prasad, R.5
  • 78
    • 77957827706 scopus 로고    scopus 로고
    • Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans
    • Puri N, Prakash O, Manoharlal R, Sharma M, Ghosh I, Prasad R. 2010. Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. Eur. J. Med. Chem. 45:4813-26
    • (2010) Eur. J. Med. Chem , vol.45 , pp. 4813-4826
    • Puri, N.1    Prakash, O.2    Manoharlal, R.3    Sharma, M.4    Ghosh, I.5    Prasad, R.6
  • 79
    • 52049084793 scopus 로고    scopus 로고
    • A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans
    • Rai V, Gaur M, Kumar A, Shukla S, Komath SS, Prasad R. 2008. A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans. Biochim. Biophys. Acta 1778:2143-53
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2143-2153
    • Rai, V.1    Gaur, M.2    Kumar, A.3    Shukla, S.4    Komath, S.S.5    Prasad, R.6
  • 80
    • 33845422375 scopus 로고    scopus 로고
    • Conserved Asp327 of Walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis
    • Rai V, Gaur M, Shukla S, Shukla S, Ambudkar SV, et al. 2006. Conserved Asp327 of Walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis. Biochemistry 45:14726-39
    • (2006) Biochemistry , vol.45 , pp. 14726-14739
    • Rai, V.1    Gaur, M.2    Shukla, S.3    Shukla, S.4    Ambudkar, S.V.5
  • 81
    • 0343903983 scopus 로고
    • Single nuclear gene inherited cross resistance and collateral sensitivity to 17 inhibitors of mitochondrial function in S. cerevisiae
    • Rank GH, Bech-Hansen NT. 1973. Single nuclear gene inherited cross resistance and collateral sensitivity to 17 inhibitors of mitochondrial function in S. cerevisiae. Mol. Gen. Genet. 126:93-102
    • (1973) Mol. Gen. Genet , vol.126 , pp. 93-102
    • Rank, G.H.1    Bech-Hansen, N.T.2
  • 83
    • 78751582384 scopus 로고    scopus 로고
    • Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study
    • Rutledge RM, Esser L, Ma J, Xia D. 2011. Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: a molecular modeling study. J. Struct. Biol. 173:333-44
    • (2011) J. Struct. Biol , vol.173 , pp. 333-344
    • Rutledge, R.M.1    Esser, L.2    Ma, J.3    Xia, D.4
  • 84
    • 0347125101 scopus 로고    scopus 로고
    • Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators
    • Safa AR. 2004. Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators. Curr. Med. Chem. Anticancer Agents 4:1-17
    • (2004) Curr. Med. Chem. Anticancer Agents , vol.4 , pp. 1-17
    • Safa, A.R.1
  • 85
    • 0028345374 scopus 로고
    • Computer-aided analyses of transport protein sequences: Gleaning evidence concerning function, structure, biogenesis, and evolution
    • Saier MH Jr. 1994. Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution. Microbiol. Rev. 58:71-93
    • (1994) Microbiol. Rev , vol.58 , pp. 71-93
    • Saier Jr., M.H.1
  • 86
    • 33646813997 scopus 로고    scopus 로고
    • Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the nondrug transporter Cdr3p
    • Saini P, Gaur NA, Prasad R. 2006. Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the nondrug transporter Cdr3p. Microbiology 152:1559-73
    • (2006) Microbiology , vol.152 , pp. 1559-1573
    • Saini, P.1    Gaur, N.A.2    Prasad, R.3
  • 87
    • 0031047670 scopus 로고    scopus 로고
    • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: Characterisation of CDR2, a newmultidrug ABC transporter gene
    • Sanglard D, Ischer F, Monod M, Bille J. 1997. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterisation of CDR2, a newmultidrug ABC transporter gene. Microbiology 143:405-16
    • (1997) Microbiology , vol.143 , pp. 405-416
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 88
    • 0002424707 scopus 로고    scopus 로고
    • Analysis of the ATP binding cassette (ABC)-transporter gene CDR4 from Candida albicans
    • Charleston, SC, 1-4 March
    • Sanglard D, Ischer F, Monod M, Dogra S, Prasad R, Bille J. 1999. Analysis of the ATP binding cassette (ABC)-transporter gene CDR4 from Candida albicans. In ASM Conf. Candida Candidiasis, Charleston, SC, 1-4 March, pp. 56.
    • (1999) ASM Conf. Candida Candidiasis , pp. 56
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Dogra, S.4    Prasad, R.5    Bille, J.6
  • 89
    • 0036488166 scopus 로고    scopus 로고
    • Resistance of Candida species to antifungal agents: Molecular mechanisms and clinical consequences
    • Sanglard D, Odds FC. 2002. Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet Infect. Dis. 2:73-85
    • (2002) Lancet Infect. Dis , vol.2 , pp. 73-85
    • Sanglard, D.1    Odds, F.C.2
  • 90
    • 58049197842 scopus 로고    scopus 로고
    • Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: Possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport
    • Sauna ZE, Bohn SS, Rutledge R, Dougherty MP, Cronin S, et al. 2008. Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport. J. Biol. Chem. 283:35010-22
    • (2008) J. Biol. Chem , vol.283 , pp. 35010-35022
    • Sauna, Z.E.1    Bohn, S.S.2    Rutledge, R.3    Dougherty, M.P.4    Cronin, S.5
  • 91
    • 0031158805 scopus 로고    scopus 로고
    • The physiological function of drug-transporting P-glycoproteins
    • Schinkel AH. 1997. The physiological function of drug-transporting P-glycoproteins. Sem. Cancer Biol. 8:161-70
    • (1997) Sem. Cancer Biol , vol.8 , pp. 161-170
    • Schinkel, A.H.1
  • 92
    • 0033485380 scopus 로고    scopus 로고
    • Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK
    • Schmees G, Stein A, Hunke S, Landmesser H, Schneider E. 1999. Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK. Eur. J. Biochem. 266:420-30
    • (1999) Eur. J. Biochem , vol.266 , pp. 420-430
    • Schmees, G.1    Stein, A.2    Hunke, S.3    Landmesser, H.4    Schneider, E.5
  • 93
    • 33744921864 scopus 로고    scopus 로고
    • Unraveling membrane-mediated substrate-transporter interactions
    • Seelig A. 2006. Unraveling membrane-mediated substrate-transporter interactions. Biophys. J. 90:3825-26
    • (2006) Biophys. J , vol.90 , pp. 3825-3826
    • Seelig, A.1
  • 94
    • 70449510475 scopus 로고    scopus 로고
    • Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts
    • Seret ML, Diffels JF, Goffeau A, Baret PV. 2009. Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeasts. BMC Genomics 10:459
    • (2009) BMC Genomics , vol.10 , pp. 459
    • Seret, M.L.1    Diffels, J.F.2    Goffeau, A.3    Baret, P.V.4
  • 95
    • 79958060479 scopus 로고    scopus 로고
    • Regulatory circuitry governing fungal development, drug resistance, and disease
    • Shapiro RS, Robbins N, Cowen LE. 2011. Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol. Mol. Biol. Rev. 75:213-67
    • (2011) Microbiol. Mol. Biol. Rev , vol.75 , pp. 213-267
    • Shapiro, R.S.1    Robbins, N.2    Cowen, L.E.3
  • 96
    • 33144465390 scopus 로고    scopus 로고
    • Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: Purified protein is amenable to intrinsic fluorescence analysis
    • Shukla S, Rai V, Banerjee D, Prasad R. 2006. Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: Purified protein is amenable to intrinsic fluorescence analysis. Biochemistry 45:2425-35
    • (2006) Biochemistry , vol.45 , pp. 2425-2435
    • Shukla, S.1    Rai, V.2    Banerjee, D.3    Prasad, R.4
  • 98
    • 39749084704 scopus 로고    scopus 로고
    • Development of inhibitors of ATP-binding cassette drug transporters: Present status and challenges
    • Shukla S, Wu CP, Ambudkar SV. 2008. Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges. Expert. Opin. Drug Metab. Toxicol. 4:205-23
    • (2008) Expert. Opin. Drug Metab. Toxicol , vol.4 , pp. 205-223
    • Shukla, S.1    Wu, C.P.2    Ambudkar, S.V.3
  • 99
    • 0037085683 scopus 로고    scopus 로고
    • ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators
    • Smriti, Krishnamurthy S, Dixit BL, Gupta CM, Milewski S, Prasad R. 2002. ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators. Yeast 19:303-18
    • (2002) Yeast , vol.19 , pp. 303-318
    • Smriti Krishnamurthy, S.1    Dixit, B.L.2    Gupta, C.M.3    Milewski, S.4    Prasad, R.5
  • 100
    • 0035038018 scopus 로고    scopus 로고
    • Effect of potassium on Saccharomyces cerevisiae resistance to fluconazole
    • Stella CA, Burgos HI. 2001. Effect of potassium on Saccharomyces cerevisiae resistance to fluconazole. Antimicrob. Agents Chemother. 45:1-2
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 1-2
    • Stella, C.A.1    Burgos, H.I.2
  • 101
    • 0022852857 scopus 로고
    • Genetic mapping of nuclear mucidin resistance mutations in Saccharomyces cerevisiae
    • Subik J, Ulaszewski S, Goffeau A. 1986. Genetic mapping of nuclear mucidin resistance mutations in Saccharomyces cerevisiae. Curr. Genet. 10:665-70
    • (1986) Curr. Genet , vol.10 , pp. 665-670
    • Subik, J.1    Ulaszewski, S.2    Goffeau, A.3
  • 102
    • 0027169843 scopus 로고
    • Proliferation of intracellular structures upon overexpression of the PMA2 ATPase in Saccharomyces cerevisiae
    • Supply P, Wach P, Thines-Sempoux D, Goffeau A. 1993. Proliferation of intracellular structures upon overexpression of the PMA2 ATPase in Saccharomyces cerevisiae. J. Biol. Chem. 268:19744-52
    • (1993) J. Biol. Chem , vol.268 , pp. 19744-19752
    • Supply, P.1    Wach, P.2    Thines-Sempoux, D.3    Goffeau, A.4
  • 103
    • 0031577724 scopus 로고    scopus 로고
    • Another link between phospholipid transmembrane migration and ABC transporter gene family, inferred from a rare inherited disorder of phosphatidylserine externalization
    • Toti F, Schindler V, Riou J-F, Lombard-Platet G, Fressinaud E, et al. 1997. Another link between phospholipid transmembrane migration and ABC transporter gene family, inferred from a rare inherited disorder of phosphatidylserine externalization. Biochem. Biophys. Res. Commun. 241:548-52
    • (1997) Biochem. Biophys. Res. Commun , vol.241 , pp. 548-552
    • Toti, F.1    Schindler, V.2    Riou, J.-F.3    Lombard-Platet, G.4    Fressinaud, E.5
  • 104
    • 0026487058 scopus 로고
    • Human P-glycoprotein transports cortisol, aldosterone and dexamethasone, but not progesterone
    • Ueda K, Okamura N, Hirai M, Tanigawara Y, Saeki T, et al. 1992. Human P-glycoprotein transports cortisol, aldosterone and dexamethasone, but not progesterone. J. Biol. Chem. 267:24248-52
    • (1992) J. Biol. Chem , vol.267 , pp. 24248-24252
    • Ueda, K.1    Okamura, N.2    Hirai, M.3    Tanigawara, Y.4    Saeki, T.5
  • 105
    • 80053361325 scopus 로고    scopus 로고
    • Aging and longevity of yeast colony populations: Metabolic adaptation and differentiation
    • Vachova L, Palkova Z. 2011. Aging and longevity of yeast colony populations: metabolic adaptation and differentiation. Biochem. Soc. Trans. 39:1471-75
    • (2011) Biochem. Soc. Trans , vol.39 , pp. 1471-1475
    • Vachova, L.1    Palkova, Z.2
  • 106
    • 0026536805 scopus 로고
    • Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein
    • Valverde MA, Diaz M, Sepulveda FV. 1992. Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature 355:830-33
    • (1992) Nature , vol.355 , pp. 830-833
    • Valverde, M.A.1    Diaz, M.2    Sepulveda, F.V.3
  • 107
    • 0007544439 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
    • Van Helvoort A, Smith AJ, Sprong H, Fritzche I, Schinkel AH, et al. 1996. MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 87:507-17
    • (1996) Cell , vol.87 , pp. 507-517
    • Van Helvoort, A.1    Smith, A.J.2    Sprong, H.3    Fritzche, I.4    Schinkel, A.H.5
  • 109
    • 0034210896 scopus 로고    scopus 로고
    • Disruption of the ABC transporter genes PDR5, YOR1, and SNQ2, and their participation in improved fermentative activity of a sake yeast mutant showing pleiotropic drug resistance
    • Watanabe M, Mizoguchi H, Nishimura A. 2000. Disruption of the ABC transporter genes PDR5, YOR1, and SNQ2, and their participation in improved fermentative activity of a sake yeast mutant showing pleiotropic drug resistance. J. Biosci. Bioeng. 89:569-76
    • (2000) J. Biosci. Bioeng , vol.89 , pp. 569-576
    • Watanabe, M.1    Mizoguchi, H.2    Nishimura, A.3
  • 110
    • 1642483020 scopus 로고    scopus 로고
    • The yeast Pdr15p ATP-binding cassette (ABC) protein is a general stress response factor implicated in cellular detoxification
    • Wolfger H, Mamnun YM, Kuchler K. 2003. The yeast Pdr15p ATP-binding cassette (ABC) protein is a general stress response factor implicated in cellular detoxification. J. Biol. Chem. 279:11593-99
    • (2003) J. Biol. Chem , vol.279 , pp. 11593-11599
    • Wolfger, H.1    Mamnun, Y.M.2    Kuchler, K.3
  • 111
    • 0035943735 scopus 로고    scopus 로고
    • The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter
    • Yuan YR, Blecker S, Martsinkevich O, Millen L, Thomas PJ, Hunt JF. 2001. The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter. J. Biol. Chem. 276:32313-21
    • (2001) J. Biol. Chem , vol.276 , pp. 32313-32321
    • Yuan, Y.R.1    Blecker, S.2    Martsinkevich, O.3    Millen, L.4    Thomas, P.J.5    Hunt, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.