Antiparallel EmrE exports drugs by exchanging between asymmetric structures

Nature

Volumn 481, Issue 7379, 2012, Pages 45-52

  Morrison, Emma A ^a   Dekoster, Gregory T ^a   Dutta, Supratik ^a   Vafabakhsh, Reza ^b   Clarkson, Michael W ^c   Bahl, Arjun ^a   Kern, Dorothee ^c   Ha, Taekjip ^b   Henzler Wildman, Katherine A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Illinois at Urbana Champaign   (United States)

^c BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; DIMER; EMRE PROTEIN; MEMBRANE PROTEIN; MONOMER; UNCLASSIFIED DRUG; WATER;

ASYMMETRY; BACTERIUM; CATION; DRUG RESISTANCE; EXPERIMENTAL STUDY; MEMBRANE; SUBSTRATE; SYMMETRY; TOPOLOGY;

ARTICLE; CRYOELECTRON MICROSCOPY; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; MICELLE; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

ANTIPORTERS; BIOLOGICAL TRANSPORT; CATALYTIC DOMAIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHARMACEUTICAL PREPARATIONS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; WATER;

ESCHERICHIA COLI;

EID: 84855455990     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10703     Document Type: Article

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