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Volumn 45, Issue 13, 2013, Pages 960-966

The brain: A new organ for the metabolic actions of SIRT1

Author keywords

adipose tissue; impaired glucose tolerance; insulin sensitivity; obesity

Indexed keywords

SIRTUIN 1; STEROIDOGENIC FACTOR 1;

EID: 84890570433     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0033-1351322     Document Type: Review
Times cited : (9)

References (68)
  • 2
    • 84859977895 scopus 로고    scopus 로고
    • Sirtuins mediate mammalian metabolic responses to nutrient availability
    • Chalkiadaki A., Guarente L. Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat Rev Endocrinol: 2012; 8 287 296
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 287-296
    • Chalkiadaki, A.1    Guarente, L.2
  • 3
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: Biological insights and disease relevance
    • Haigis M. C., Sinclair D. A. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol: 2012; 5 253 295
    • (2012) Annu Rev Pathol , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 4
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • DOI 10.1038/35001622
    • Imai S., Armstrong C. M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature: 2000; 403 795 800 (Pubitemid 30111843)
    • (2000) Nature , vol.403 , Issue.6771 , pp. 795-800
    • Imai, S.-I.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 5
    • 0037130175 scopus 로고    scopus 로고
    • Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
    • DOI 10.1038/nature00829
    • Lin S. J., Kaeberlein M., Andalis A. A., Sturtz L. A., Defossez P. A., Culotta V. C., Fink G. R., Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature: 2002; 418 344 348 (Pubitemid 34790687)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 344-348
    • Lin, S.-J.1    Kaeberlein, M.2    Andalis, A.A.3    Sturtz, L.A.4    Defossez, P.-A.5    Culotta, V.C.6    Fink, G.R.7    Guarente, L.8
  • 7
    • 34247259630 scopus 로고    scopus 로고
    • Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
    • DOI 10.1038/sj.emboj.7601633, PII 7601633
    • Gerhart-Hines Z., Rodgers J. T., Bare O., Lerin C., Kim S. H., Mostoslavsky R., Alt F. W., Wu Z., Puigserver P. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J: 2007; 26 1913 1923 (Pubitemid 46624046)
    • (2007) EMBO Journal , vol.26 , Issue.7 , pp. 1913-1923
    • Gerhart-Hines, Z.1    Rodgers, J.T.2    Bare, O.3    Lerin, C.4    Kim, S.-H.5    Mostoslavsky, R.6    Alt, F.W.7    Wu, Z.8    Puigserver, P.9
  • 8
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B
    • DOI 10.1016/j.cmet.2007.08.014, PII S1550413107002598
    • Sun C., Zhang F., Ge X., Yan T., Chen X., Shi X., Zhai Q. 2007 SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab: 2007; 6 307 319 (Pubitemid 47468091)
    • (2007) Cell Metabolism , vol.6 , Issue.4 , pp. 307-319
    • Sun, C.1    Zhang, F.2    Ge, X.3    Yan, T.4    Chen, X.5    Shi, X.6    Zhai, Q.7
  • 19
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • DOI 10.1126/science.1098014
    • Araki T., Sasaki Y., Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science: 2004; 305 1010 1013 (Pubitemid 39071777)
    • (2004) Science , vol.305 , Issue.5686 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 22
    • 77955046461 scopus 로고    scopus 로고
    • SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
    • Donmez G., Wang D., Cohen D. E., Guarente L. SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell: 2010; 142 320 332
    • (2010) Cell , vol.142 , pp. 320-332
    • Donmez, G.1    Wang, D.2    Cohen, D.E.3    Guarente, L.4
  • 25
    • 77955344258 scopus 로고    scopus 로고
    • SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus
    • Satoh A., Brace C. S., Ben-Josef G., West T., Wozniak D. F., Holtzman D. M., Herzog E. D., Imai S. SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J Neurosci: 2010; 30 10220 10232
    • (2010) J Neurosci , vol.30 , pp. 10220-10232
    • Satoh, A.1    Brace, C.S.2    Ben-Josef, G.3    West, T.4    Wozniak, D.F.5    Holtzman, D.M.6    Herzog, E.D.7    Imai, S.8
  • 28
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
    • DOI 10.1038/nature03354
    • Rodgers J. T., Lerin C., Haas W., Gygi S. P., Spiegelman B. M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature: 2005; 434 113 118 (Pubitemid 40349395)
    • (2005) Nature , vol.434 , Issue.7029 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 29
    • 77953292242 scopus 로고    scopus 로고
    • Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
    • Dominy J. E. Jr, Lee Y., Gerhart-Hines Z., Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochim Biophy Acta: 2010; 1804 1676 1683
    • (2010) Biochim Biophy Acta , vol.1804 , pp. 1676-1683
    • Dominy Jr., J.E.1    Lee, Y.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 33
    • 63449112017 scopus 로고    scopus 로고
    • Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation
    • Purushotham A., Schug T. T., Xu Q., Surapureddi S., Guo X., Li X. Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metab: 2009; 9 327 338
    • (2009) Cell Metab , vol.9 , pp. 327-338
    • Purushotham, A.1    Schug, T.T.2    Xu, Q.3    Surapureddi, S.4    Guo, X.5    Li, X.6
  • 34
    • 78650533816 scopus 로고    scopus 로고
    • Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition
    • Wang R. H., Li C., Deng C. X. Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition. Inter J Biol Sci: 2010; 6 682 690
    • (2010) Inter J Biol Sci , vol.6 , pp. 682-690
    • Wang, R.H.1    Li, C.2    Deng, C.X.3
  • 35
    • 34948883324 scopus 로고    scopus 로고
    • SIRT1 Deacetylates and Positively Regulates the Nuclear Receptor LXR
    • DOI 10.1016/j.molcel.2007.07.032, PII S109727650700620X
    • Li X., Zhang S., Blander G., Tse J. G., Krieger M., Guarente L. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell: 2007; 28 91 106 (Pubitemid 47531974)
    • (2007) Molecular Cell , vol.28 , Issue.1 , pp. 91-106
    • Li, X.1    Zhang, S.2    Blander, G.3    Tse, J.G.4    Krieger, M.5    Guarente, L.6
  • 37
  • 39
    • 79953206276 scopus 로고    scopus 로고
    • Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism
    • Vetterli L., Brun T., Giovannoni L., Bosco D., Maechler P. Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. J Biol Chem: 2011; 286 6049 6060
    • (2011) J Biol Chem , vol.286 , pp. 6049-6060
    • Vetterli, L.1    Brun, T.2    Giovannoni, L.3    Bosco, D.4    Maechler, P.5
  • 42
    • 65249102660 scopus 로고    scopus 로고
    • The deacetylase enzyme SIRT1 is not associated with oxidative capacity in rat heart and skeletal muscle and its overexpression reduces mitochondrial biogenesis
    • Gurd B. J., Yoshida Y., Lally J., Holloway G. P., Bonen A. The deacetylase enzyme SIRT1 is not associated with oxidative capacity in rat heart and skeletal muscle and its overexpression reduces mitochondrial biogenesis. J Physiol: 2009; 587 1817 1828
    • (2009) J Physiol , vol.587 , pp. 1817-1828
    • Gurd, B.J.1    Yoshida, Y.2    Lally, J.3    Holloway, G.P.4    Bonen, A.5
  • 46
    • 33845985335 scopus 로고    scopus 로고
    • SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer- binding protein α transcriptional complex
    • DOI 10.1074/jbc.M607215200
    • Qiao L., Shao J. SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. J Biol Chem: 2006; 281 39915 39924 (Pubitemid 46041795)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.52 , pp. 39915-39924
    • Qiao, L.1    Shao, J.2
  • 47
    • 37549052177 scopus 로고    scopus 로고
    • Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes
    • Wang H., Qiang L., Farmer S. R. Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes. Mol Cell Biol: 2008; 28 188 200
    • (2008) Mol Cell Biol , vol.28 , pp. 188-200
    • Wang, H.1    Qiang, L.2    Farmer, S.R.3
  • 49
    • 82255183479 scopus 로고    scopus 로고
    • SirT1: A guardian at the gates of adipose tissue inflammation
    • Cho K. W., Lumeng C. N. SirT1: a guardian at the gates of adipose tissue inflammation. Diabetes: 2011; 60 3100 3102
    • (2011) Diabetes , vol.60 , pp. 3100-3102
    • Cho, K.W.1    Lumeng, C.N.2
  • 50
    • 84869805159 scopus 로고    scopus 로고
    • The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1
    • Yang Z., Wang X., He Y., Qi L., Yu L., Xue B., Shi H. The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1. PloS One: 2012; 7 e49935
    • (2012) PloS One , vol.7
    • Yang, Z.1    Wang, X.2    He, Y.3    Qi, L.4    Yu, L.5    Xue, B.6    Shi, H.7
  • 55
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M., Smiley D. L., Heiman M. L. Ghrelin induces adiposity in rodents. Nature: 2000; 407 908 913
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 59
    • 79959726080 scopus 로고    scopus 로고
    • Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function
    • Wu D., Qiu Y., Gao X., Yuan X. B., Zhai Q. Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function. PloS One: 2011; 6 e21759
    • (2011) PloS One , vol.6
    • Wu, D.1    Qiu, Y.2    Gao, X.3    Yuan, X.B.4    Zhai, Q.5
  • 61
    • 84875431034 scopus 로고    scopus 로고
    • High-dose resveratrol supplementation in obese men: An investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
    • Poulsen M. M., Vestergaard P. F., Clasen B. F., Radko Y., Christensen L. P., Stodkilde-Jorgensen H., Moller N., Jessen N., Pedersen S. B., Jorgensen J. O. High-dose resveratrol supplementation in obese men: an investigator- initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes: 2013; 62 1186 1195
    • (2013) Diabetes , vol.62 , pp. 1186-1195
    • Poulsen, M.M.1    Vestergaard, P.F.2    Clasen, B.F.3    Radko, Y.4    Christensen, L.P.5    Stodkilde-Jorgensen, H.6    Moller, N.7    Jessen, N.8    Pedersen, S.B.9    Jorgensen, J.O.10
  • 66
    • 72849130743 scopus 로고    scopus 로고
    • Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
    • Cohen D. E., Supinski A. M., Bonkowski M. S., Donmez G., Guarente L. P. Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev: 2009; 23 2812 2817
    • (2009) Genes Dev , vol.23 , pp. 2812-2817
    • Cohen, D.E.1    Supinski, A.M.2    Bonkowski, M.S.3    Donmez, G.4    Guarente, L.P.5
  • 67
    • 82255183409 scopus 로고    scopus 로고
    • WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis
    • Wu J., Zhang F., Yan M., Wu D., Yu Q., Zhang Y., Zhou B., McBurney M. W., Zhai Q. WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis. Diabetes: 2011; 60 3197 3207
    • (2011) Diabetes , vol.60 , pp. 3197-3207
    • Wu, J.1    Zhang, F.2    Yan, M.3    Wu, D.4    Yu, Q.5    Zhang, Y.6    Zhou, B.7    McBurney, M.W.8    Zhai, Q.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.