The Full Capacity of AICAR to Reduce Obesity-Induced Inflammation and Insulin Resistance Requires Myeloid SIRT1

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Yang, Zhenggang ^a,b   Wang, Xianfeng ^a   He, Yin ^c   Qi, Ling ^c   Yu, Liqing ^d   Xue, Bingzhong ^a,e   Shi, Hang ^a,e  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c Department of Obstetrics Gynecology   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

^e GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; CD206 ANTIGEN; DEOXYGLUCOSE C 14; GLUCOSE; GLUCOSE TRITIUM; GLYCOPROTEIN P 15095; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOPHANE INSULIN; LYMPHOCYTE ANTIGEN; MONOCYTE CHEMOTACTIC PROTEIN 1; RADIOPHARMACEUTICAL AGENT; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY WEIGHT; CHRONIC DRUG ADMINISTRATION; CONTINUOUS INFUSION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; EPIDIDYMIS FAT; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID DIET; LIVER; LOW DRUG DOSE; MACROPHAGE ACTIVATION; MACROPHAGE ALTERNATIVE POLARIZATION; MALE; MOUSE; NONHUMAN; OBESITY; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; DIET, HIGH-FAT; GLUCOSE; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; MACROPHAGE-1 ANTIGEN; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MYELOID CELLS; OBESITY; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; SIRTUIN 1;

ANIMALIA; MUS;

EID: 84869805159     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049935     Document Type: Article

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