-
1
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009;182:4499-4506
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
2
-
-
33846434093
-
The terminology issue for myeloid-derived suppressor cells [1]
-
DOI 10.1158/0008-5472.CAN-06-3037
-
Gabrilovich DI, Bronte V, Chen SH, et al. The terminology issue for myeloid-derived suppressor cells. Cancer Res 2007;67:425, author reply 6. (Pubitemid 46142802)
-
(2007)
Cancer Research
, vol.67
, Issue.1
, pp. 425
-
-
Gabrilovich, D.I.1
Bronte, V.2
Chen, S.-H.3
Colombo, M.P.4
Ochoa, A.5
Ostrand-Rosenberg, S.6
Schreiber, H.7
-
3
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009;9:162-174
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
4
-
-
33749425534
-
+ T cells
-
DOI 10.1172/JCI28828
-
Gallina G, Dolcetti L, Serafini P, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 2006;116:2777-2790 (Pubitemid 44511641)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.10
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
De Santo, C.4
Marigo, I.5
Colombo, M.P.6
Basso, G.7
Brombacher, F.8
Borrello, I.9
Zanovello, P.10
Bicciato, S.11
Bronte, V.12
-
5
-
-
25844501447
-
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma
-
DOI 10.1084/jem.20050715
-
Rodriguez PC, Hernandez CP, Quiceno D, et al. Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma. J Exp Med 2005;202:931-939 (Pubitemid 41396893)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.7
, pp. 931-939
-
-
Rodriguez, P.C.1
Hernandez, C.P.2
Quiceno, D.3
Dubinett, S.M.4
Zabaleta, J.5
Ochoa, J.B.6
Gilbert, J.7
Ochoa, A.C.8
-
6
-
-
34447118098
-
+ T cell tolerance in cancer
-
DOI 10.1038/nm1609, PII NM1609
-
Nagaraj S, Gupta K, Pisarev V, et al. Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer. Nat Med 2007;13:828-835 (Pubitemid 47038194)
-
(2007)
Nature Medicine
, vol.13
, Issue.7
, pp. 828-835
-
-
Nagaraj, S.1
Gupta, K.2
Pisarev, V.3
Kinarsky, L.4
Sherman, S.5
Kang, L.6
Herber, D.L.7
Schneck, J.8
Gabrilovich, D.I.9
-
7
-
-
0041850021
-
Inhibition of myeloid cell differentiation in cancer: The role of reactive oxygen species
-
DOI 10.1189/jlb.0103010
-
Kusmartsev S, Gabrilovich DI. Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species. J Leukoc Biol 2003;74:186-196 (Pubitemid 38040415)
-
(2003)
Journal of Leukocyte Biology
, vol.74
, Issue.2
, pp. 186-196
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
8
-
-
70350133511
-
IL4Rα+ myeloid-derived suppressor cell expansion in cancer patients
-
Mandruzzato S, Solito S, Falisi E, et al. IL4Rα+ myeloid-derived suppressor cell expansion in cancer patients. J Immunol 2009;182:6562-6568
-
(2009)
J Immunol
, vol.182
, pp. 6562-6568
-
-
Mandruzzato, S.1
Solito, S.2
Falisi, E.3
-
9
-
-
54049134747
-
Subsets of myeloid-derived suppressor cells in tumor-bearing mice
-
Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008;181:5791-5802
-
(2008)
J Immunol
, vol.181
, pp. 5791-5802
-
-
Youn, J.I.1
Nagaraj, S.2
Collazo, M.3
Gabrilovich, D.I.4
-
10
-
-
43249130187
-
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
-
Movahedi K, Guilliams M, Van den Bossche J, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 2008;111:4233-4244
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
Guilliams, M.2
Van Den Bossche, J.3
-
11
-
-
0035164478
-
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
-
Almand B, Clark JI, Nikitina E, et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 2001;166:678-689 (Pubitemid 32038493)
-
(2001)
Journal of Immunology
, vol.166
, Issue.1
, pp. 678-689
-
-
Almand, B.1
Clark, J.I.2
Nikitina, E.3
Van Beynen, J.4
English, N.R.5
Knight, S.C.6
Carbone, D.P.7
Gabrilovich, D.I.8
-
12
-
-
0035201127
-
Tumor-induced immune dysfunctions caused by myeloid suppressor cells
-
DOI 10.1097/00002371-200111000-00001
-
Bronte V, Serafini P, Apolloni E, Zanovello P, et al. Tumor-induced immune dysfunctions caused by myeloid suppressor cells. J Immunother 2001;24:431-446 (Pubitemid 33104863)
-
(2001)
Journal of Immunotherapy
, vol.24
, Issue.6
, pp. 431-446
-
-
Bronte, V.1
Serafini, P.2
Apolloni, E.3
Zanovello, P.4
-
13
-
-
41149119143
-
Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
-
DOI 10.1111/j.1600-065X.2008.00602.x
-
Marigo I, Dolcetti L, Serafini P, Zanovello P, Bronte V. Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev 2008;222:162-179 (Pubitemid 351430364)
-
(2008)
Immunological Reviews
, vol.222
, Issue.1
, pp. 162-179
-
-
Marigo, I.1
Dolcetti, L.2
Serafini, P.3
Zanovello, P.4
Bronte, V.5
-
14
-
-
25144466458
-
+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
DOI 10.1158/1078-0432.CCR-05-0883
-
Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 2005;11:6713-6721 (Pubitemid 41339014)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.18
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
15
-
-
34547630506
-
A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
-
Ko HJ, Kim YJ, Kim YS, et al. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res 2007;67:7477-7486
-
(2007)
Cancer Res
, vol.67
, pp. 7477-7486
-
-
Ko, H.J.1
Kim, Y.J.2
Kim, Y.S.3
-
17
-
-
41549145181
-
Immunogenicity of anthracyclines: Moving towards more personalized medicine
-
Apetoh L, Mignot G, Panaretakis T, Kroemer G, Zitvogel L. Immunogenicity of anthracyclines: moving towards more personalized medicine. Trends Mol Med 2008;14:141-151
-
(2008)
Trends Mol Med
, vol.14
, pp. 141-151
-
-
Apetoh, L.1
Mignot, G.2
Panaretakis, T.3
Kroemer, G.4
Zitvogel, L.5
-
18
-
-
62049085194
-
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
-
Panaretakis T, Kepp O, Brockmeier U, et al. Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J 2009;28:578-590
-
(2009)
EMBO J
, vol.28
, pp. 578-590
-
-
Panaretakis, T.1
Kepp, O.2
Brockmeier, U.3
-
19
-
-
76649097628
-
Membrane Hsp72 from tumor-derived exosomes mediates pStat3 dependent immunosuppressive function of myeloid derived suppressor cells
-
Chalmin F, Ladoire S, Mignot G, et al. Membrane Hsp72 from tumor-derived exosomes mediates pStat3 dependent immunosuppressive function of myeloid derived suppressor cells. J Clin Invest 2010:120.
-
(2010)
J Clin Invest
, vol.120
-
-
Chalmin, F.1
Ladoire, S.2
Mignot, G.3
-
20
-
-
0034671610
-
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes
-
Apolloni E, Bronte V, Mazzoni A, et al. Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes. J Immunol 2000;165:6723-6730 (Pubitemid 32001135)
-
(2000)
Journal of Immunology
, vol.165
, Issue.12
, pp. 6723-6730
-
-
Apolloni, E.1
Bronte, V.2
Mazzoni, A.3
Serafini, P.4
Cabrelle, A.5
Segal, D.M.6
Young, H.A.7
Zanovello, P.8
-
21
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
DOI 10.1038/nrc1074
-
Longley DB, Harkin DP, Johnston PG. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330-338 (Pubitemid 37328853)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
23
-
-
12244262239
-
Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency
-
DOI 10.1258/000456303321016150
-
van Kuilenburg AB, De Abreu RA, van Gennip AH. Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency. Ann Clin Biochem 2003;40:41-45 (Pubitemid 36051408)
-
(2003)
Annals of Clinical Biochemistry
, vol.40
, Issue.1
, pp. 41-45
-
-
Van Kuilenburg, A.B.P.1
De Abreu, R.A.2
Van Gennip, A.H.3
-
24
-
-
25844504654
-
+ regulatory T cell proliferation
-
DOI 10.1084/jem.20050463
-
Ghiringhelli F, Puig PE, Roux S, et al. Tumor cells convert immature myeloid dendritic cells into TGF-β-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J Exp Med 2005;202:919-929 (Pubitemid 41396892)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.7
, pp. 919-929
-
-
Ghiringhelli, F.1
Puig, P.E.2
Roux, S.3
Parcellier, A.4
Schmitt, E.5
Solary, E.6
Kroemer, G.7
Martin, F.8
Chauffert, B.9
Zitvogel, L.10
-
25
-
-
1642378018
-
+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
-
DOI 10.1002/eji.200324181
-
Ghiringhelli F, Larmonier N, Schmitt E, et al. CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative. Eur J Immunol 2004;34:336-344 (Pubitemid 39255944)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.2
, pp. 336-344
-
-
Ghiringhelli, F.1
Larmonier, N.2
Schmitt, E.3
Parcellier, A.4
Cathelin, D.5
Garrido, C.6
Chauffert, B.7
Solary, E.8
Bonnotte, B.9
Martin, F.10
-
26
-
-
55849130757
-
CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer
-
Roux S, Apetoh L, Chalmin F, et al. CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer. J Clin Invest 2008;118:3751-3761
-
(2008)
J Clin Invest
, vol.118
, pp. 3751-3761
-
-
Roux, S.1
Apetoh, L.2
Chalmin, F.3
-
27
-
-
70149097098
-
Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation
-
Tanaka H, Matsushima H, Nishibu A, Clausen BE, Takashima A. Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation. Cancer Res 2009;69:6987-6994
-
(2009)
Cancer Res
, vol.69
, pp. 6987-6994
-
-
Tanaka, H.1
Matsushima, H.2
Nishibu, A.3
Clausen, B.E.4
Takashima, A.5
-
28
-
-
68349123372
-
Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism
-
Shurin GV, Tourkova IL, Kaneno R, Shurin MR. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism. J Immunol 2009;183:137-144
-
(2009)
J Immunol
, vol.183
, pp. 137-144
-
-
Shurin, G.V.1
Tourkova, I.L.2
Kaneno, R.3
Shurin, M.R.4
-
29
-
-
34948820602
-
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
-
DOI 10.1038/nm1622, PII NM1622
-
Apetoh L, Ghiringhelli F, Tesniere A, et al. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 2007;13:1050-1059 (Pubitemid 47517504)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1050-1059
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Obeid, M.4
Ortiz, C.5
Criollo, A.6
Mignot, G.7
Maiuri, M.C.8
Ullrich, E.9
Saulnier, P.10
Yang, H.11
Amigorena, S.12
Ryffel, B.13
Barrat, F.J.14
Saftig, P.15
Levi, F.16
Lidereau, R.17
Nogues, C.18
Mira, J.-P.19
Chompret, A.20
Joulin, V.21
Clavel-Chapelon, F.22
Bourhis, J.23
Andre, F.24
Delaloge, S.25
Tursz, T.26
Kroemer, G.27
Zitvogel, L.28
more..
-
30
-
-
26844464792
-
+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-β-dependent manner
-
DOI 10.1084/jem.20051511
-
Ghiringhelli F, Menard C, Terme M, et al. CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-β-dependent manner. J Exp Med 2005;202:1075-1085 (Pubitemid 41464501)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.8
, pp. 1075-1085
-
-
Ghiringhelli, F.1
Menard, C.2
Terme, M.3
Flament, C.4
Taieb, J.5
Chaput, N.6
Puig, P.E.7
Novault, S.8
Escudier, B.9
Vivier, E.10
Lecesne, A.11
Robert, C.12
Blay, J.-Y.13
Bernard, J.14
Caillat-Zucman, S.15
Freitas, A.16
Tursz, T.17
Wagner-Ballon, O.18
Capron, C.19
Vainchencker, W.20
Martin, F.21
Zitvogel, L.22
more..
-
31
-
-
34248194231
-
Tregs and rethinking cancer immunotherapy
-
Curiel TJ. Tregs and rethinking cancer immunotherapy. J Clin Invest 2007;117:1167-1174
-
(2007)
J Clin Invest
, vol.117
, pp. 1167-1174
-
-
Curiel, T.J.1
-
32
-
-
33847368549
-
+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
-
DOI 10.1007/s00262-006-0225-8
-
Ghiringhelli F, Menard C, Puig PE, et al. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 2007;56:641-648 (Pubitemid 46348738)
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.5
, pp. 641-648
-
-
Ghiringhelli, F.1
Menard, C.2
Puig, P.E.3
Ladoire, S.4
Roux, S.5
Martin, F.6
Solary, E.7
Le Cesne, A.8
Zitvogel, L.9
Chauffert, B.10
-
33
-
-
68849128500
-
Therapeutic targeting of myeloid-derived suppressor cells
-
Ugel S, Delpozzo F, Desantis G, et al. Therapeutic targeting of myeloid-derived suppressor cells. Curr Opin Pharmacol 2009;9:470-481
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 470-481
-
-
Ugel, S.1
Delpozzo, F.2
Desantis, G.3
-
34
-
-
15944410592
-
+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
-
DOI 10.1182/blood-2004-06-2410
-
Lutsiak ME, Semnani RT, De Pascalis R, Kashmiri SV, Schlom J, Sabzevari H. Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 2005;105:2862-2868 (Pubitemid 40446280)
-
(2005)
Blood
, vol.105
, Issue.7
, pp. 2862-2868
-
-
Lutsiak, M.E.C.1
Semnani, R.T.2
De Pascalis, R.3
Kashmiri, S.V.S.4
Schlom, J.5
Sabzevari, H.6
-
35
-
-
67349250111
-
Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: A role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy
-
van der Most RG, Currie AJ, Mahendran S, et al. Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy. Cancer Immunol Immunother 2009;58:1219-1228
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1219-1228
-
-
Van Der Most, R.G.1
Currie, A.J.2
Mahendran, S.3
-
36
-
-
21144454780
-
Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
-
Ercolini AM, Ladle BH, Manning EA, et al. Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. J Exp Med 2005;201:1591-1602
-
(2005)
J Exp Med
, vol.201
, pp. 1591-1602
-
-
Ercolini, A.M.1
Ladle, B.H.2
Manning, E.A.3
-
37
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Sakaguchi S, Houghton AN. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 2004;200:771-782
-
(2004)
J Exp Med
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
Guevara-Patino, J.A.2
Rizzuto, G.A.3
Engelhorn, M.E.4
Sakaguchi, S.5
Houghton, A.N.6
-
38
-
-
33751531874
-
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
-
DOI 10.1084/jem.20061104
-
Serafini P, Meckel K, Kelso M, et al. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med 2006;203:2691-2702 (Pubitemid 44833345)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2691-2702
-
-
Serafini, P.1
Meckel, K.2
Kelso, M.3
Noonan, K.4
Califano, J.5
Koch, W.6
Dolcetti, L.7
Bronte, V.8
Borrello, I.9
-
39
-
-
0033562982
-
+ T cell responses by dysregulating antigen-presenting cell maturation
-
Bronte V, Chappell DB, Apolloni E, et al. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. J Immunol 1999;162:5728-5737 (Pubitemid 29314923)
-
(1999)
Journal of Immunology
, vol.162
, Issue.10
, pp. 5728-5737
-
-
Bronte, V.1
Chappell, D.B.2
Apolloni, E.3
Cabrelle, A.4
Wang, M.5
Hwu, P.6
Restifo, N.P.7
-
40
-
-
10744220561
-
Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte-mediated Tumor Immunosurveillance: Abrogation Prevents Tumor Recurrence
-
DOI 10.1084/jem.20022227
-
Terabe M, Matsui S, Park JM, et al. Transforming growth factor-β production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 2003;198:1741-1752 (Pubitemid 37494166)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.11
, pp. 1741-1752
-
-
Terabe, M.1
Matsui, S.2
Park, J.-M.3
Mamura, M.4
Noben-Trauth, N.5
Donaldson, D.D.6
Chen, W.7
Wahl, S.M.8
Ledbetter, S.9
Pratt, B.10
Letterio, J.J.11
Paul, W.E.12
Berzofsky, J.A.13
|