The impact of ageing on natural killer cell function and potential consequences for health in older adults

Ageing Research Reviews

Volumn 12, Issue 4, 2013, Pages 1069-1078

  Hazeldine, Jon ^a   Lord, Janet M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Ageing; Immunesenescence; Natural killer (NK) cells

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CD94 ANTIGEN; CHEMOKINE RECEPTOR CCR3; CYTOCHROME C; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 8; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; L SELECTIN; LAMIN B; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2A; PERFORIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADAPTIVE IMMUNITY; AGING; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; BACTERIAL CLEARANCE; BACTERIAL INFECTION; CELL DEATH; CELL MATURATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOLOGY; CYTOSOL; DENDRITIC CELL; DNA REPAIR; ENZYME ACTIVATION; EXOCYTOSIS; HUMAN; INCIDENCE; INFLUENZA VACCINATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LEUKOCYTE MIGRATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTOTOXICITY; MACROPHAGE; MICROBIAL IMMUNITY; MONOCYTE; MYCOBACTERIUM TUBERCULOSIS; MYCOSIS; NATURAL KILLER CELL; NONHUMAN; PHAGOCYTE; PHENOTYPE; PROTEIN EXPRESSION; REVIEW; SENESCENCE; VACCINATION; VIRUS INFECTION;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

ADCC; AGEING; ANTIBODY DEPENDENT CELL CYTOTOXICITY; APAF-1; APOPTOSIS-ACTIVATING FACTOR 1; BH3-INTERACTING DOMAIN; BID; CAD; CASPASE-ACTIVATED DNASE; CMV; CYTOMEGALOVIRUS; DC; DENDRITIC CELL; DLN; DRAINING LYMPH NODE; FADD; FAS LIGAND; FAS-ASSOCIATED PROTEIN WITH DEATH DOMAIN; FASL; ICAD; IFN-Γ; IL-8; IMMUNESENESCENCE; INHIBITOR OF CASPASE-ACTIVATED DNASE; INTERFERON GAMMA; INTERLEUKIN 8; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KIR; MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA; MAJOR HISTOCOMPATIBILITY COMPLEX; MHC; MHC CLASS I-CHAIN-RELATED PROTEIN; MIC; MIP-1Α; MYCOBACTERIUM TUBERCULOSIS; NATURAL CYTOTOXICITY RECEPTOR; NATURAL KILLER (NK) CELLS; NATURAL KILLER CELL; NATURAL KILLER CELL CYTOTOXICITY; NCR; NK CELL; NKCC; PARP; PBLS; PERIPHERAL BLOOD LYMPHOCYTES; PHORBOL 12-MYRISTATE 13-ACETATE; PMA; POLY ADPRIBOSE POLYMERASE; T HELPER 1 CELL; TB; TBID; TH-1; TNF-Α; TRAIL; TRUNCATED BH3-INTERACTING DOMAIN; TUMOR NECROSIS FACTOR RELATED APOPTOTIC-INDUCING LIGAND; TUMOUR NECROSIS FACTOR ALPHA;

ADULT; AGED; AGING; APOPTOSIS; CELL AGING; HEALTH STATUS; HUMANS; KILLER CELLS, NATURAL; MIDDLE AGED;

EID: 84888206218     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2013.04.003     Document Type: Review

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