Regulation of Fas and Fas-ligand expression in NK cells by cytokines and the involvement of FAS-ligand in NK/LAK cell-mediated cytotoxicity

Cytokine

Volumn 9, Issue 6, 1997, Pages 394-404

  Medvedev, Andrei E ^a   Johnsen, Ann Charlotte ^a   Haux, Johan ^a   Steinkjer, Bjørg ^a   Egeberg, Kjartan ^a   Lynch, David H ^b   Sundan, Anders ^a   Espevik, Terje ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b AMGEN INC   (United States)

Author keywords

Cytotoxicity; Fas; Fas ligand; LAK; NK

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; CYTOKINE; FAS ANTIGEN; HYBRID PROTEIN; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 7; LIGAND; MONOCLONAL ANTIBODY;

ARTICLE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOKINE ACTIVATED KILLER CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN INDUCTION;

EID: 0031172517     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0181     Document Type: Article

References (45)

1. 1. Trauth BC, Klas C, Peters AMJ, Matzku, S, Moller P, Falk W, Debatin K-M, Krammer PH (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245:301-305.
2. 2. Yonehara S, Ishii A, Yonehara M (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 169:1747-1756.
3. 3. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S-I, Sameshima M, Hase A, Seto Y, Nagata S (1991) The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233-243.
4. 4. Krammer PH, Dhein J, Walczak H, Behrman I, Mariani S, Matiba B, Fath M, Daniel PT, Knipping E, Westendorp MO, Stricker K, Baumler C, Hellbard S, Germer M, Peter ME, Debatin KM (1994) The role of APO-1 mediated apoptosis in the immune system. Immunol Rev 142:175-191.
5. 5. Nagata S, Golstein P (1995) The Fas death factor. Science 267:1449-1456.
6. 6. Suda T, Takahashi T, Golstein P, Nagata S (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169-1178.
7. 7. Beutler B, van Huffel C (1994) Unraveling function in the TNF ligand and receptor families. Science 264:667-668.
8. 8. Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S (1995) Expression of the Fas ligand in cells of T cell lineage. J Immunol 5:3806-3813.
9. 9. Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboul A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF, Green DR (1995) Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441-448.
10. 10. Badley AD, McElhinny JA, Leibson PJ, Lynch DH, Alderson MR, Paya CV (1996) Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J Virol 70:199-206.
11. 11. Arase H, Arase N, Saito TJ (1995) Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 181: 1235-1238.
12. 12. Montel AH, Bochan MR, Hobbs JA, Lynch DH, Brahmi A (1995) Fas involvement in cytotoxicity mediated by human NK cells. Cell Immunol 166:236-246.
13. 13. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S (1992) Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317.
14. 14. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S (1994) Generalized lympho-proliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976.
15. 15. Lynch DH, Watson ML, Alderson MR, Baum PR, Miller RE, Tough T, Gibson M, Davis-Smith T, Smith CA, Hunter K, Bhat D, Goodwin RG, Seldin MF (1994) The mouse Fas-ligand gene is mutated in gld mice and is a part of the TNF family gene cluster. Immunity 1:131-136.
16. 16. Alderson MR, Tough T, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F, Lynch DH (1995) Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 181:71-77.
17. 17. Hanabuchi S, Koyanagi M, Kawasaki A, Shinohara N, Matsuzawa A, Nishimura Y, Kobayashi Y, Yonehara S, Yagita H, Okumura K (1994) Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci USA 91:4930-4934.
18. 18. Ramsdell F, Seaman MS, Miller RE, Picha KS, Kennedy MK, Lynch DH (1994) Differntial ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. Int Immunol 6:1545-1553.
19. 19. Alderson MR, Armitage RJ, Maraskovsky E, Tough TW, Roux E, Schooley K, Ramsdell F, Lynch DH (1993) Fas transduces activation signals in normal human T lymphocytes. J Exp Med 178:2231-2235.
20. 20. Lynch DH, Ramsdell F, Alderson MR (1995) Fas and FasL in the homeostatic regulation of immune responses. Immunol Today 16:569-574.
21. 21. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA (1995) Fas ligand-induced apoptosis is a mechanism of immune priviledge. Science 270:1189-1192.
22. 22. Bellgrau D, Gold D, Selawry H, Moore J, Franzusoff A, Duke RC (1995) A role for CD95 ligand in preventing graft rejection. Nature 377:630-632.
23. 23. Hiramatsu N, Hayashi N, Katayama K, Mochizuki K, Kawanishi Y, Kasahara A, Fusamoto H, Kamada T (1994) Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 19:1354-1359.
24. 24. Debatin KM, Fahrig-Faissner A, Enenkel-Stoodt S, Kreuz W, Benner A, Krammer PH (1994) High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children. Blood 83:3101-3103.
25. 25. Katsikis P, Wunderlich E, Smith C, Herzenberg L, Herzenberg L (1995) Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 181:2029-2036.
26. 26. Falk MH, Trauth BC, Debatin KM, Klas C, Gregory CD, Rickinson AB, Calender A, Lenoir GM, Ellwart JW, Krammer PH, et al. (1992) Expression of the APO-1 antigen in Burkitt lymphoma cell line correlates with a shift towards a lymphoblastoid phenotype. Blood 79:3300-3333.
27. 27. Tanaka M, Suda T, Haze K, Nakamura N, Sato K, Kimura F, Motoyashi K, Mizuki M, Tagawa S, Ohga S, Hatake K, Drummond AH, Nagata S (1996) Fas ligand in human serum. Nature Medicine 2:317-322.
28. 28. Mariani SM, Matiba B, Baumler C, Krammer PH (1995) Regulation of cell surface APO-1/Fas (CD95) ligand expression by metalloproteases. Eur J Immunol 25:2303-2307.
29. 29. Yagita H, Hanabuchi S, Asano Y, Tamura T, Nariuchi H, Okumura K (1995) Fas-mediated cytotoxicity - a new immuno-regulatory and pathogenic function of Th1 CD4 + T cells. Immunol Rev 146:223-239.
30. 30. Naume B, Nonstad U, Steinkjer B, Funderud S, Smeland E, Espevik T (1991) Immunomagnetic isolation of NK and LAK cells. J Immunol Methods 1136:1-9.
31. 31. Takahashi T, Tanaka M, Inazawa J, Abe T, Suda T, Nagata S (1994) Human Fas ligand: gene structure, chromosomal location and species specificity. Int Immunol 6:1567-1674.
32. + natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. Eur J Immunol 23:1831-1838.
33. 33. Robertson MJ, Manley TJ, Pichert G, Cameron C, Cochran KJ, Levine H, Ritz J (1995) Functional consequences of APO-1/Fas (CD95) antigen expression by normal and neoplastic hematopoietic cells. Leukemia and Lymphoma 17:51-61.
34. 34. Ramsdell F, Seaman MS, Miller RE, Tough TW, Alderson MR, Lynch DH (1994) gld/gld mice are unable to express a functional ligand for Fas. Eur J Immunol 24:928-933.
35. 35. Yang Y, Mercep M, Ware CF, Ashwell JD (1995) Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids. J Exp Med 181:1673-1682.
36. + NK cells. J Immunol 148:2429-2436.
37. 37. Lanier LL, Buck DW, Rhodes L, Ding A, Evans E, Barney C, Phillips JH (1988) Interleukin-2 activation of natural killer cells rapidly induces the expression and phosphorilation of the Leu-23 antigen. J Exp Med 167:1572-1585.
38. 38. Seaman WE, Niemi EC, Stark MR, Goldfien RD, Pollock AS, Imboden JB (1991) Molecular cloning of gp42, a cell surface molecule that is selectively induced on rat natural killer cells by interleukin-2: glycolipid membrane anchoring and capacity for transmembrane signaling. J Exp Med 173:251-260.
39. 39. Sugita K, Robertson MJ, Torimoto Y, Ritz J, Schlossman SF, Morimoto C (1992) Participation of the CD27 antigen in the regulation of IL-2-activated human natural killer cells. J Immunol 149:1199-1203.
40. 40. Rivoltini L, Cattoretti G, Arienti F, Mastroianni A, Melani C, Colombo MP, Parmiani G (1991) The high lysability by LAK cells of colon-carcinoma cells resistant to doxorubicin is associated with a high expression of ICAM-1, LFA-3, NCA and a less-differentiated phenotype. Int J Cancer 47:746-754.
41. 41. Velotti F, Palmieri G, D'Ambrosio D, Piccoli M, Frati M, Santoni A (1992) Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine-activated killer cells with NK phenotype (LAK-NK) Eur J Immunol 22:1049-1053.
42. 42. Darmon AJ, Nicholson DW, Bleackley, RC (1995) Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377:446-448.
43. 43. Podack ER, Hengartner H, Lichtenheld MG (1991) A central role of perforin in cytolysis? Annu Rev Immunol 9:129-157.
44. 44. Nakajima H., Henkart PA (1994) Cytotoxic lymphocytes granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown. J Immunol 152: 1057-1063.
45. 45. Gough NM (1988) Rapid and quantitative preparation of cytoplasmic RNA from small number of cells. Anal Biochem 173:93-95.