메뉴 건너뛰기




Volumn 161, Issue 8, 1998, Pages 3957-3965

Molecular mechanisms of immune-mediated lysis of murine renal cancer: Differential contributions of perforin-dependent versus fas-mediated pathways in lysis by NK and T cells

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; GAMMA INTERFERON; PERFORIN; STAUROSPORINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032532283     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (79)

References (71)
  • 1
    • 0023934095 scopus 로고
    • Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for the treatment of murine renal cancer
    • Wiltrout, R. H., M. R. Boyd, T. C. Back, R. R. Salup, J. A. Arthur, and R. L. Hornung. 1988. Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for the treatment of murine renal cancer. J. Immunol. 140:3261.
    • (1988) J. Immunol. , vol.140 , pp. 3261
    • Wiltrout, R.H.1    Boyd, M.R.2    Back, T.C.3    Salup, R.R.4    Arthur, J.A.5    Hornung, R.L.6
  • 2
    • 0023685071 scopus 로고
    • Augmentation of natural killer cell activity, induction of IFN, and development of tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2
    • Hornung, R. L., T. C. Back, D. S. Zaharko, W. J. Urba, D. L. Longo, and R. H. Wiltrout. 1988. Augmentation of natural killer cell activity, induction of IFN, and development of tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2. J. Immunol. 141:3671.
    • (1988) J. Immunol. , vol.141 , pp. 3671
    • Hornung, R.L.1    Back, T.C.2    Zaharko, D.S.3    Urba, W.J.4    Longo, D.L.5    Wiltrout, R.H.6
  • 3
    • 0030067276 scopus 로고    scopus 로고
    • Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal cancer
    • Wigginton, J. W., K. L. Komschlies, T. C. Back, J. L. Franco, M. J. Brunda, and R. H. Wiltrout. 1996. Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal cancer. J. Natl. Cancer Inst. 88:38.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 38
    • Wigginton, J.W.1    Komschlies, K.L.2    Back, T.C.3    Franco, J.L.4    Brunda, M.J.5    Wiltrout, R.H.6
  • 4
    • 0030900415 scopus 로고    scopus 로고
    • Immunostimulatory therapy with anti-CD3 monoclonal antibodies and recombinant interleukin-2: Heightened in vivo expression of mRNA encoding cytotoxic attack molecules and immunoregulatory cytokines and regression of murine renal cancer
    • Asano, T., A. Khanna, M. Lagman, B. Li, and M. Suthanthiran. 1997. Immunostimulatory therapy with anti-CD3 monoclonal antibodies and recombinant interleukin-2: heightened in vivo expression of mRNA encoding cytotoxic attack molecules and immunoregulatory cytokines and regression of murine renal cancer. J. Urol. 157:2396.
    • (1997) J. Urol. , vol.157 , pp. 2396
    • Asano, T.1    Khanna, A.2    Lagman, M.3    Li, B.4    Suthanthiran, M.5
  • 5
    • 0025166798 scopus 로고
    • Antitumor effects of α-interferon and γ-interferon on a murine renal cancer (Renca) in vitro and in vivo
    • Sayers, T. J., T. A. Wiltrout, K. McCormick, C. Husted, and R. H. Wiltrout. 1990. Antitumor effects of α-interferon and γ-interferon on a murine renal cancer (Renca) in vitro and in vivo. Cancer Res. 50:5414.
    • (1990) Cancer Res. , vol.50 , pp. 5414
    • Sayers, T.J.1    Wiltrout, T.A.2    McCormick, K.3    Husted, C.4    Wiltrout, R.H.5
  • 6
    • 3543123639 scopus 로고
    • The immunotherapy of murine renal cancer
    • Wiltrout, R. H. 1991. The immunotherapy of murine renal cancer. Prog. Neuroendocrinimmunol. 4:154.
    • (1991) Prog. Neuroendocrinimmunol. , vol.4 , pp. 154
    • Wiltrout, R.H.1
  • 8
    • 0028940744 scopus 로고
    • Execution and suicide: Cytotoxic lymphocytes enforce draconian laws through separate molecular pathways
    • Podack, E. R. 1995. Execution and suicide: cytotoxic lymphocytes enforce draconian laws through separate molecular pathways. Curr. Opin. Immunol. 7:11.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 11
    • Podack, E.R.1
  • 10
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata, S., and P. Golstein. 1995. The Fas death factor. Science 267:1449.
    • (1995) Science , vol.267 , pp. 1449
    • Nagata, S.1    Golstein, P.2
  • 11
    • 0031001834 scopus 로고    scopus 로고
    • The Fas-based mechanism of lymphocytotoxicity
    • Berke, G. 1997. The Fas-based mechanism of lymphocytotoxicity. Hum. Immunol. 54:1.
    • (1997) Hum. Immunol. , vol.54 , pp. 1
    • Berke, G.1
  • 12
    • 0028483262 scopus 로고
    • Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecules
    • Henkart, P. A. 1994. Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules. Immunity 1:343.
    • (1994) Immunity , vol.1 , pp. 343
    • Henkart, P.A.1
  • 13
    • 0028064701 scopus 로고
    • Segregation of APO-1/Fas antigen- and tumor necrosis factor receptor-mediated apoptosis
    • Grell, M., P. H. Krammer, and P. Scheurich. 1994. Segregation of APO-1/Fas antigen- and tumor necrosis factor receptor-mediated apoptosis. Eur. J. Immunol. 24:2563.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2563
    • Grell, M.1    Krammer, P.H.2    Scheurich, P.3
  • 14
    • 0028204376 scopus 로고
    • Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways
    • Wong, G. H. W., and D. V. Goeddel. 1994. Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways. J. Immunol. 152:1751.
    • (1994) J. Immunol. , vol.152 , pp. 1751
    • Wong, G.H.W.1    Goeddel, D.V.2
  • 15
    • 0026568919 scopus 로고
    • Lymphoproliferative disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferative disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 16
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969.
    • (1994) Cell , vol.76 , pp. 969
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 18
    • 0031307852 scopus 로고    scopus 로고
    • + T cells clear influenza virus by perforin or Fas-dependent processes
    • + T cells clear influenza virus by perforin or Fas-dependent processes. J. Immunol. 159:5197.
    • (1997) J. Immunol. , vol.159 , pp. 5197
    • Topham, D.J.1    Tripp, R.A.2    Doherty, P.C.3
  • 20
    • 0027990763 scopus 로고
    • Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells: Induction and modulation of sensitivity by cytokines
    • Weller, M., K. Frei, P. Groscurth, P. H. Krammer, Y. Yonekawa, and A. Fontana. 1994. Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells: induction and modulation of sensitivity by cytokines. J. Clin. Invest. 94:954.
    • (1994) J. Clin. Invest. , vol.94 , pp. 954
    • Weller, M.1    Frei, K.2    Groscurth, P.3    Krammer, P.H.4    Yonekawa, Y.5    Fontana, A.6
  • 23
    • 0028327190 scopus 로고
    • Anti-Fas on nonhematopoetic tumors: Levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness
    • Owen-Schaub, L. B., R. Radinsky, E. Kruzel, K. Berry, and S. Yonehara. 1994. Anti-Fas on nonhematopoetic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness. Cancer Res. 54:1580.
    • (1994) Cancer Res. , vol.54 , pp. 1580
    • Owen-Schaub, L.B.1    Radinsky, R.2    Kruzel, E.3    Berry, K.4    Yonehara, S.5
  • 25
    • 0030942793 scopus 로고    scopus 로고
    • Xenospecific cytotoxic T lymphocytes: Potent lysis in vitro and in vivo
    • Smyth, M. J., M. H. Kershaw, and J. A. Trapani. 1997. Xenospecific cytotoxic T lymphocytes: potent lysis in vitro and in vivo. Transplantation 63:1171.
    • (1997) Transplantation , vol.63 , pp. 1171
    • Smyth, M.J.1    Kershaw, M.H.2    Trapani, J.A.3
  • 26
    • 0029827025 scopus 로고    scopus 로고
    • Xenospecific cytotoxic T lymphocytes use the perforin- and Fas-mediated lytic pathways
    • Smyth, M. J., V. R. Sutton, M. H. Kershaw, and J. A. Trapani. 1996. Xenospecific cytotoxic T lymphocytes use the perforin- and Fas-mediated lytic pathways. Transplantation 62:1529.
    • (1996) Transplantation , vol.62 , pp. 1529
    • Smyth, M.J.1    Sutton, V.R.2    Kershaw, M.H.3    Trapani, J.A.4
  • 27
    • 0029030247 scopus 로고
    • Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in Eu L-MYC transgenic mice but not in animals infected with MoMuLV
    • Zornig, M., A. Grzeschiczek, M.-B. Kawalski, K.-U. Hartmann, and T. Moroy. 1995. Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in Eu L-MYC transgenic mice but not in animals infected with MoMuLV. Oncogene 10:2397.
    • (1995) Oncogene , vol.10 , pp. 2397
    • Zornig, M.1    Grzeschiczek, A.2    Kawalski, M.-B.3    Hartmann, K.-U.4    Moroy, T.5
  • 30
    • 0031572509 scopus 로고    scopus 로고
    • Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes
    • Hornung, F., L. Zheng, and M. J. Lenardo. 1997. Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes. J. Immunol. 159:3816.
    • (1997) J. Immunol. , vol.159 , pp. 3816
    • Hornung, F.1    Zheng, L.2    Lenardo, M.J.3
  • 34
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff, M. C. 1992. Social controls on cell survival and cell death. Nature 356:397.
    • (1992) Nature , vol.356 , pp. 397
    • Raff, M.C.1
  • 35
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267:1456.
    • (1995) Science , vol.267 , pp. 1456
    • Thompson, C.B.1
  • 39
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S. 1997. Apoptosis by death factor. Cell 88:355.
    • (1997) Cell , vol.88 , pp. 355
    • Nagata, S.1
  • 40
    • 0031252369 scopus 로고    scopus 로고
    • Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
    • Sabelko, K. A., K. A. Kelly, M. H. Cross, and J. H. Russell. 1997. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J. Immunol. 159:3096.
    • (1997) J. Immunol. , vol.159 , pp. 3096
    • Sabelko, K.A.1    Kelly, K.A.2    Cross, M.H.3    Russell, J.H.4
  • 41
    • 0031253737 scopus 로고    scopus 로고
    • Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
    • Waldner, H., R. A. Sobel, E. Howard, and V. K. Kuchroo. 1997. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. J. Immunol. 159:3100.
    • (1997) J. Immunol. , vol.159 , pp. 3100
    • Waldner, H.1    Sobel, R.A.2    Howard, E.3    Kuchroo, V.K.4
  • 42
    • 0031279189 scopus 로고    scopus 로고
    • Fas-mediated liver damage in MRL hematopoetic chimeras undergoing lpr-mediated graft-versus-host disease
    • Bobé, P., D. Bonardelle, M. Reynès, F. Godeau, J. Mahiou, V. Joulin, and N. Kiger. 1997. Fas-mediated liver damage in MRL hematopoetic chimeras undergoing lpr-mediated graft-versus-host disease. J. Immunol. 159:4197.
    • (1997) J. Immunol. , vol.159 , pp. 4197
    • Bobé, P.1    Bonardelle, D.2    Reynès, M.3    Godeau, F.4    Mahiou, J.5    Joulin, V.6    Kiger, N.7
  • 43
    • 0031570449 scopus 로고    scopus 로고
    • Fas ligand-mediated bystander lysis of syngeneic cells in response to an allogeneic stimulus
    • Smyth, M. J. 1997. Fas ligand-mediated bystander lysis of syngeneic cells in response to an allogeneic stimulus. J. Immunol. 158:5765.
    • (1997) J. Immunol. , vol.158 , pp. 5765
    • Smyth, M.J.1
  • 44
    • 0031155385 scopus 로고    scopus 로고
    • Perforin, Fas/Fas ligand, and TNF-α pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL
    • Ando, K., K. Hiroishi, T. Kanedo, T. Moriyama, Y. Muto, N. Kayagaki, H. Yagita, K. Okumura, and M. Imawari. 1997. Perforin, Fas/Fas ligand, and TNF-α pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. J. Immunol. 158:5283.
    • (1997) J. Immunol. , vol.158 , pp. 5283
    • Ando, K.1    Hiroishi, K.2    Kanedo, T.3    Moriyama, T.4    Muto, Y.5    Kayagaki, N.6    Yagita, H.7    Okumura, K.8    Imawari, M.9
  • 45
    • 0030796003 scopus 로고    scopus 로고
    • Modulation of resistance to anti-APO-1-induced apoptosis in osteosarcoma cells by cytokines
    • Fellenberg, J., H. Mau, C. Scheuerflug, V. Ewerbeck, and K. Debatin. 1997. Modulation of resistance to anti-APO-1-induced apoptosis in osteosarcoma cells by cytokines. Int. J. Cancer 72:536.
    • (1997) Int. J. Cancer , vol.72 , pp. 536
    • Fellenberg, J.1    Mau, H.2    Scheuerflug, C.3    Ewerbeck, V.4    Debatin, K.5
  • 46
    • 0030994132 scopus 로고    scopus 로고
    • The interferon receptors
    • Peska, S. 1997. The interferon receptors. Semin. Oncol. 24:S9-18.
    • (1997) Semin. Oncol. , vol.24
    • Peska, S.1
  • 48
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan, A. M., K. O'Rourke, M. Tewari, and V. M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505.
    • (1995) Cell , vol.81 , pp. 505
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 49
    • 0028913550 scopus 로고
    • A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
    • Boldin, M. P., E. E. Varfolomeev, Z. Pancer, I. L. Mett, J. H. Chamonis, and D. Wallach. 1995. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J. Biol. Chem. 270:7795.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7795
    • Boldin, M.P.1    Varfolomeev, E.E.2    Pancer, Z.3    Mett, I.L.4    Chamonis, J.H.5    Wallach, D.6
  • 50
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT/FADD-interacting protease. in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin, M. P., T. M. Goncharov, Y. V. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT/FADD-interacting protease. in Fas/APO-1- and TNF receptor-induced cell death. Cell 85:803.
    • (1996) Cell , vol.85 , pp. 803
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 52
    • 0030892138 scopus 로고    scopus 로고
    • Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GrzB nuclear localization
    • Shi, L., S. Mai, S. Israels, K. Browne, J. A. Trapani, and A. H. Greenberg. 1997. Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GrzB nuclear localization. J. Exp. Med. 185:855.
    • (1997) J. Exp. Med. , vol.185 , pp. 855
    • Shi, L.1    Mai, S.2    Israels, S.3    Browne, K.4    Trapani, J.A.5    Greenberg, A.H.6
  • 53
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon, A. J., D. W. Nicolson, and R. C. Bleackley. 1995. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377:446.
    • (1995) Nature , vol.377 , pp. 446
    • Darmon, A.J.1    Nicolson, D.W.2    Bleackley, R.C.3
  • 58
    • 0023032471 scopus 로고
    • Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells
    • Liu, C.-C. B. Perussia, Z. A. Cohn, and J. D.-E. Young. 1986. Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells. J. Exp. Med. 164:2061.
    • (1986) J. Exp. Med. , vol.164 , pp. 2061
    • Liu, C.-C.1    Perussia, B.2    Cohn, Z.A.3    Young, J.D.-E.4
  • 59
    • 0011830309 scopus 로고
    • Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease
    • Gershenfeld, H. K., R. J. Herschberger, T. B. Shows, and I. L. Weissman. 1988. Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease. Proc. Natl. Acad. Sci. USA 85:1184.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1184
    • Gershenfeld, H.K.1    Herschberger, R.J.2    Shows, T.B.3    Weissman, I.L.4
  • 60
    • 0023688825 scopus 로고
    • Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes
    • Trapani, J. A., J. L. Klein, P. C. White, and B. Dupont. 1988. Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes. Proc. Natl. Acad. Sci. USA 85:6924.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6924
    • Trapani, J.A.1    Klein, J.L.2    White, P.C.3    Dupont, B.4
  • 61
    • 0027265549 scopus 로고
    • Modulation of perforin and granzyme messenger RNA expression in human natural killer cells
    • Salcedo, T. W., L. Azzoni, S. F. Wolf, and B. Perussia. 1993. Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J. Immunol. 151:2511.
    • (1993) J. Immunol. , vol.151 , pp. 2511
    • Salcedo, T.W.1    Azzoni, L.2    Wolf, S.F.3    Perussia, B.4
  • 62
    • 0028962125 scopus 로고
    • Fas-mediated cytotoxicity by freshly isolated natural killer cells
    • Arase, H., N. Arase, and T. Saito. 1995. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J. Exp. Med. 181:1235.
    • (1995) J. Exp. Med. , vol.181 , pp. 1235
    • Arase, H.1    Arase, N.2    Saito, T.3
  • 63
    • 0024326938 scopus 로고
    • Perforin and serine esterase gene expression in stimulated human T cells: Kinetics, mitogen requirements, and effects of cyclosporin A
    • Liu, C., S. Rafii, A. Graniello-Piperno, J. A. Trapani, and J. D-E. Young. 1989. Perforin and serine esterase gene expression in stimulated human T cells: kinetics, mitogen requirements, and effects of cyclosporin A. J. Exp. Med. 170:2105.
    • (1989) J. Exp. Med. , vol.170 , pp. 2105
    • Liu, C.1    Rafii, S.2    Graniello-Piperno, A.3    Trapani, J.A.4    Young, J.D.-E.5
  • 68
    • 0029060187 scopus 로고
    • The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation
    • Luster, A. D., S. M. Greenberg, and P. Leder. 1995. The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J. Exp. Med. 182:219.
    • (1995) J. Exp. Med. , vol.182 , pp. 219
    • Luster, A.D.1    Greenberg, S.M.2    Leder, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.