Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

Cancer Letters

Volumn 341, Issue 2, 2013, Pages 139-149

  Shrimali, Deepti ^a   Shanmugam, Muthu K ^a   Kumar, Alan Prem ^a,b,c,d   Zhang, Jingwen ^a   Tan, Benny K H ^a   Ahn, Kwang Seok ^e   Sethi, Gautam ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c CURTIN UNIVERSITY   (Australia)

^d UNIVERSITY OF NORTH TEXAS   (United States)

^e Kyung Hee University   (South Korea)

Author keywords

Angiogenesis; Apoptosis; Cancer; Emodin; Metastasis

Indexed keywords

BAICALIN; CAPECITABINE; CISPLATIN; EMODIN; GEMCITABINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOMYCIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SIMVASTATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROTEIN KINASE INHIBITOR;

ACUTE HEART INFARCTION; ACUTE HEMORRHAGIC PANCREATITIS; ACUTE PANCREATITIS; ALZHEIMER DISEASE; ANAPHYLAXIS; ANTIANGIOGENIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTHRITIS; ASTHMA; ATHEROSCLEROSIS; CANCER INHIBITION; CANCER RESISTANCE; CELL CYCLE ARREST; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; DRUG POTENTIATION; GLOMERULONEPHRITIS; HEART PROTECTION; HUMAN; INFLAMMATORY DISEASE; LEUKEMIA; LIVER CELL CARCINOMA; LYMPHOMA; METASTASIS INHIBITION; MULTIDRUG RESISTANCE; MYOCARDITIS; NEOPLASM; NEUROPROTECTION; NONHUMAN; PANCREAS CANCER; PANCREATITIS; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; SKIN TUMOR; TUMOR REGRESSION; BIOLOGICAL MODEL; DRUG EFFECTS; INFLAMMATION; METABOLISM; NEOPLASMS; PATHOPHYSIOLOGY;

BACTERIA (MICROORGANISMS); RHEUM PALMATUM;

EMODIN; HUMANS; INFLAMMATION; MODELS, BIOLOGICAL; NEOPLASMS; NF-KAPPA B; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84887178584     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.08.023     Document Type: Review

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