Emodin inhibits tumor necrosis factor-α-induced migration and inflammatory responses in rat aortic smooth muscle cells

International Journal of Molecular Medicine

Volumn 29, Issue 6, 2012, Pages 999-1006

  Meng, Liang ^a   Yan, Dongming ^a   Xu, Weidong ^b   Ma, Jian ^a   Chen, Bin ^c   Feng, Hong ^a  

^a SHENYANG MEDICAL COLLEGE   (China)

^b Fengtian Hospital   (China)

^c Fourth People's Hospital of Shenyang   (China)

Author keywords

Emodin; Inflammation; Matrix metalloproteinase 9 2; Migration; Nuclear factor B; Vascular smooth muscle cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA ACTIN; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; EMODIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN CINC 2BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; AORTA MEDIA; ARTICLE; ATHEROSCLEROSIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HERBAL MEDICINE; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ANIMALS; AORTA; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMODIN; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MATRIX METALLOPROTEINASES; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860525324     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.940     Document Type: Article

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