Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells

British Journal of Pharmacology

Volumn 161, Issue 7, 2010, Pages 1628-1644

  Meng, Guoquan ^a   Liu, Yiyao ^a   Lou, Changchun ^a   Yang, Hong ^a  

^a UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Anti inflammation; Emodin; HUVECs; NF B; TLR 4

Indexed keywords

CD14 ANTIGEN; EMODIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; METHYL BETA CYCLODEXTRIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 4;

ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LIPID RAFT; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTIGENS, CD14; ATHEROSCLEROSIS; BETA-CYCLODEXTRINS; CELL SURVIVAL; CELLS, CULTURED; CHOLESTEROL; CYTOKINES; EMODIN; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MEMBRANE MICRODOMAINS; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 78149405277     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00993.x     Document Type: Article

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