Emodin and rhein inhibit LIGHT-induced monocytes migration by blocking of ROS production

Vascular Pharmacology

Volumn 53, Issue 1-2, 2010, Pages 28-37

  Heo, Sook Kyoung ^a   Yun, Hyun Jeong ^a   Noh, Eui Kyu ^b   Park, Sun Dong ^a  

^a Dongguk University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Anti atherosclerosis agent; Emodin; Inflammatory response; LIGHT; Rhein

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYLFLUORIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; EMODIN; ENZYME INHIBITOR; HERPESVIRUS ENTRY MEDIATOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; LIGHT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; RHEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CELL MIGRATION; CELL STRAIN THP 1; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL;

ANTHRAQUINONES; ATHEROSCLEROSIS; CELL LINE; CELL MOVEMENT; EMODIN; ENZYME INHIBITORS; HUMANS; MONOCYTES; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14;

EID: 77952426455     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2010.03.002     Document Type: Article

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