The effects of emodin on the expression of cytokines and functions of leukocytes from Sprague-Dawley rats

In Vivo

Volumn 20, Issue 1, 2006, Pages 147-152

  Yu, Fu Shun ^a   Yu, Chun Shu ^a   Chan, Jack Kai Sheng ^b   Kuo, Hsiu Maan ^a   Lin, Jing Pin ^a   Tang, Nou Ying ^a   Chang, Yung Hsien ^a   Chung, Jing Gung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cytokines; Emodin; Leukocyte function

Indexed keywords

CYTOKINE; EMODIN; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL ISOLATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; LEUKOCYTE CULTURE; LEUKOCYTE FUNCTION; MACROPHAGE FUNCTION; MALE; NATURAL KILLER CELL; NONHUMAN; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RAT; RAT STRAIN;

EID: 30844459014     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Stern EI, Quan N, Proescholdt MG and Herkenham M: Spatiotemporal induction patterns of cytokine and related immune signal molecule mRNAs in response to intrastriatal injection of lipopolysaccharide. J Neuroimmunol 109: 245-260, 2000.
2. Schnell I, Fearn S, Klassen H, Schwab ME and Perry VH: Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord. Eur J Neurosci 11: 3648-3658, 1999.
3. Tsai TH: Analytical approaches for traditional Chinese medicines exhibiting antineoplastic activity. J Chromator B Biomed Sci Appl 764: 27-48, 2001.
4. Yang F, Zhang T, Tian G, Cao H, Liu Q and Ito Y: Preparative isolation and purification of hydroxyanthraquinones from Rheum officinale Baill by high-speed counter-current chromatography using pH-modulated stepwise elution. J Chromatog A 858: 103-178, 1999.
5. Wang HH and Chung JG: Emodin-induced inhibition of growth and DNA damage in Helicobacter pylori. Curr Microbiol 35: 262-266, 1997.
6. Chung JG, Wang HH, Wu LT, Chang SS and Chang WC: Inhibitory actions of emodin on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients. Food Chem Toxicol 35: 1001-1007, 1997.
7. Barnard DL, Huffman JH, Morris JL, Wood SG, Hughes BG and Sidwell RW: Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus. Antivir Res 17: 63-77, 1992.
8. Chang CJ, Ashendel CL, Geahlen RL, McLaughlin JL and Waters DJ: Oncogene signal transduction inhibitors from medicinal plants. In Vivo 10: 185-190, 1996.
9. Huang HC, Chang JH, Tung SF, Wu RT, Foegh ML and Chu SH: Immunosuppressive effect of emodin, a free radical generator. Eur J Pharmacol 211: 359-364, 1992.
10. Kuo YC, Sun CM, Ou JC and Tsai WJ: A tumor cell growth inhibitor from Polygonum hypolecucum Ohwi. Life Sci 61: 2335-2344, 1997.
11. Zhang L, Chang CJ, Bacus SS and Hung MC: Suppressed transformation and induced differentiation of HER-2/neuoverexpressing breast cancer cells by emodin. Cancer Res 55: 3890-3896, 1995.
12. Cha TL, Qiu L, Chen CT, Wen Y and Hung MC: Emodin downregulates androgen receptor and inhibits prostate cancer cell growth. Cancer Res 65: 2287-2295, 2005.
13. Nagashima H, Nakamura K and Goto T: Hepatotoxin rubratoxin B induced the secretion of TNF-α, IL-8, and MCP-1 in HL60 cells. Biochem Biophys Res Commun 287: 829-832, 2001.
14. Yang JS, Kok LF, Lin YH, Kao CC, Yang JL, Lin CC, Chen GW, Huang WW and Chung JG: Diallyl disulfide inhibits WEHI-3 leukemia cells in Balb/C mice in vivo. Anticancer Res 2006 (in press).
15. Li TM, Chen GW, Su CC, Lin JG, Yeh CC, Cheng KC and Chung JG: Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells. Anticancer Res 25: 971-979, 2005.
16. Yeh CC, Wu LT, Lin SY, Li TM and Chung JG: The inhibition of N-acetyltransferase activity and gene expression in human bladder cancer cells (T24) by shikonin. In Vivo 18: 21-32, 2004.
17. Chung JG, Lu HF, Yeh CC, Cheng KC, Liu SS and Lee JH: Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide. Food Chem Toxicol 42: 195-202, 2004.
18. Yang J, Li H, Chen YY, Wang XJ, Shi GY, Hu QS, Kang XL, Lu Y, Tang XM, Guo QS and Yi J: Anthraquinones sensitize tumor cells to arsenic cytotoxicity in vitro and in vivo via reactive oxygen species-mediated dual regulation of apoptosis. Free Radic Biol Med 37: 2027-2041, 2004.
19. Chan TM, Leung K Tsang RC, Liu ZH, Li LS and Yung S: Emodin ameliorates glucose-induced matrix synthesis in human peritoneal mesothelial cells. Kidney Int 64: 519-533, 2003.
20. Shieh DE, Chen YY, Yen MH, Chiang LC and Lin CC: Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells. Life Sci 74: 2279-2290, 2004.
21. Lin CC, Chang CH, Yang JJ, Namba T and Hattori M: Hepatoprotective effects of emodin from Ventilago leiocarpa. J Ethnopharmacol 52: 107-111, 1996.
22. Huang YS, Wu JC, Chang FY and Lee SD: Interleukin-8 and alcoholic liver disease. Chin Med J 62: 395-401, 1999.
23. Dy M, Pacilio M, Arnould A, Machavoine F, Mayeux P, Hermine O, Bodger M and Schneider E: Modulation of histidine decarboxylase activity and cytokine synthesis in human leukemic cell lines: relationship with basophilic and/or megakaryocytic differentiation. Exp Hematol 27: 1295-1305, 1999.
24. Kasahara T, Mukaida N, Yamashita K, Yagisawa H, Akahoshi T and Matsushima K: IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line. Immunology 74: 60-67, 1991.
25. Luster MI, Simeonova PP, Gallucci R and Matheson J: Tumor necrosis factor and toxicology. Crit Rev Toxicol 29: 91-511, 1999.